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Volumn 115, Issue 14, 2010, Pages 2784-2795

Gfi-1B controls human erythroid and megakaryocytic differentiation by regulating TGF-β signaling at the bipotent erythro-megakaryocytic progenitor stage

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH FACTOR; GROWTH FACTOR INDEPENDENCE 1B; SMAD2 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION INTERMEDIARY FACTOR 1 GAMMA; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

EID: 77950986252     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2009-09-241752     Document Type: Article
Times cited : (70)

References (43)
  • 1
    • 0142180052 scopus 로고    scopus 로고
    • Gfi-1 oncoproteins in hematopoiesis
    • Duan Z, Horwitz M. Gfi-1 oncoproteins in hematopoiesis. Hematology. 2003;8(5):339-344.
    • (2003) Hematology , vol.8 , Issue.5 , pp. 339-344
    • Duan, Z.1    Horwitz, M.2
  • 4
    • 0029897536 scopus 로고    scopus 로고
    • Gfi-1 encodes a nuclear zinc finger protein that binds DNA and functions as a transcriptional repressor
    • Zweidler-Mckay PA, Grimes HL, Flubacher MM, Tsichlis PN. Gfi-1 encodes a nuclear zinc finger protein that binds DNA and functions as a transcriptional repressor. Mol Cell Biol. 1996;16(8):4024-4034.
    • (1996) Mol Cell Biol , vol.16 , Issue.8 , pp. 4024-4034
    • Zweidler-Mckay, P.A.1    Grimes, H.L.2    Flubacher, M.M.3    Tsichlis, P.N.4
  • 5
    • 7244231429 scopus 로고    scopus 로고
    • Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells
    • DOI 10.1038/nature02994
    • Hock H, Hamblen MJ, Rooke HM, et al. Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells. Nature. 2004;431(7011):1002-1007. (Pubitemid 39434423)
    • (2004) Nature , vol.431 , Issue.7011 , pp. 1002-1007
    • Hock, H.1    Hamblen, M.J.2    Rooke, H.M.3    Schindler, J.W.4    Saleque, S.5    Fujiwara, Y.6    Orkin, S.H.7
  • 6
    • 8144220648 scopus 로고    scopus 로고
    • Transcription factor Gfi1 regulates self-renewal and engraftment of hematopoietic stem cells
    • DOI 10.1038/sj.emboj.7600419
    • Zeng H, Yucel R, Kosan C, Klein-Hitpass L, Moroy T. Transcription factor Gfi1 regulates self-renewal and engraftment of hematopoietic stem cells. EMBO J. 2004;23(20):4116-4125. (Pubitemid 39472432)
    • (2004) EMBO Journal , vol.23 , Issue.20 , pp. 4116-4125
    • Zeng, H.1    Yucel, R.2    Kosan, C.3    Klein-Hitpass, L.4    Moroy, T.5
  • 7
    • 0036467868 scopus 로고    scopus 로고
    • The zinc-finger proto-oncogene Gfi-1b is essential for development of the erythroid and megakaryocytic lineages
    • DOI 10.1101/gad.959102
    • Saleque S, Cameron S, Orkin SH. The zinc-finger proto-oncogene Gfi-1b is essential for development of the erythroid and megakaryocytic lineages. Genes Dev. 2002;16(3):301-306. (Pubitemid 34111410)
    • (2002) Genes and Development , vol.16 , Issue.3 , pp. 301-306
    • Saleque, S.1    Cameron, S.2    Orkin, S.H.3
  • 8
    • 14244258985 scopus 로고    scopus 로고
    • Direct transcriptional repression of the genes encoding the zinc-finger proteins Gfi1b and Gfi1 by Gfi1b
    • DOI 10.1093/nar/gki243
    • Vassen L, Fiolka K, Mahlmann S, Moroy T. Direct transcriptional repression of the genes encoding the zinc-finger proteins Gfi1b and Gfi1 by Gfi1b. Nucleic Acids Res. 2005;33(3):987-998. (Pubitemid 41430519)
    • (2005) Nucleic Acids Research , vol.33 , Issue.3 , pp. 987-998
    • Vassen, L.1    Fiolka, K.2    Mahlmann, S.3    Moroy, T.4
  • 9
    • 0027462484 scopus 로고
    • Progression of interleukin-2 (IL-2)-dependent rat T cell lymphoma lines to IL-2-independent growth following activation of a gene (Gfi-1) encoding a novel zinc finger protein
    • Gilks CB, Bear SE, Grimes HL, Tsichlis PN. Progression of interleukin-2 (IL-2)-dependent rat T cell lymphoma lines to IL-2-independent growth following activation of a gene (Gfi-1) encoding a novel zinc finger protein. Mol Cell Biol. 1993;13(3):1759-1768.
    • (1993) Mol Cell Biol , vol.13 , Issue.3 , pp. 1759-1768
    • Gilks, C.B.1    Bear, S.E.2    Grimes, H.L.3    Tsichlis, P.N.4
  • 10
    • 0036510161 scopus 로고    scopus 로고
    • Inflammatory reactions and severe neutropenia in mice lacking the transcriptional repressor Gfi1
    • Karsunky H, Zeng H, Schmidt T, et al. Inflammatory reactions and severe neutropenia in mice lacking the transcriptional repressor Gfi1. Nat Genet. 2002;30(3):295-300.
    • (2002) Nat Genet , vol.30 , Issue.3 , pp. 295-300
    • Karsunky, H.1    Zeng, H.2    Schmidt, T.3
  • 11
    • 67049108074 scopus 로고    scopus 로고
    • Gfi1 integrates progenitor versus granulocytic transcriptional programming
    • Horman SR, Velu CS, Chaubey A, et al. Gfi1 integrates progenitor versus granulocytic transcriptional programming. Blood. 2009;113(22):5466-5475.
    • (2009) Blood , vol.113 , Issue.22 , pp. 5466-5475
    • Horman, S.R.1    Velu, C.S.2    Chaubey, A.3
  • 12
    • 13544273833 scopus 로고    scopus 로고
    • Gfi-1B plays a critical role in terminal differentiation of normal and transformed erythroid progenitor cells
    • DOI 10.1182/blood-2003-11-4068
    • Garcon L, Lacout C, Svinartchouk F, et al. Gfi-1B plays a critical role in terminal differentiation of normal and transformed erythroid progenitor cells. Blood. 2005;105(4):1448-1455. (Pubitemid 40223660)
    • (2005) Blood , vol.105 , Issue.4 , pp. 1448-1455
    • Garcon, L.1    Lacout, C.2    Svinartchouk, F.3    Le Couedic, J.-P.4    Villeval, J.-L.5    Vainchenker, W.6    Dumenil, D.7
  • 13
    • 0037108193 scopus 로고    scopus 로고
    • Erythroid expansion mediated by the Gfi-1B zinc finger protein: Role in normal hematopoiesis
    • Osawa M, Yamaguchi T, Nakamura Y, et al. Erythroid expansion mediated by the Gfi-1B zinc finger protein: role in normal hematopoiesis. Blood. 2002;100(8):2769-2777.
    • (2002) Blood , vol.100 , Issue.8 , pp. 2769-2777
    • Osawa, M.1    Yamaguchi, T.2    Nakamura, Y.3
  • 14
    • 33947251378 scopus 로고    scopus 로고
    • Gfi1b:green fluorescent protein knock-in mice reveal a dynamic expression pattern of Gfi1b during hematopoiesis that is largely complementary to Gfi1
    • DOI 10.1182/blood-2006-06-030031
    • Vassen L, Okayama T, Moroy T. Gfi1b:green fluorescent protein knock-in mice reveal a dynamic expression pattern of Gfi1b during hematopoiesis that is largely complementary to Gfi1. Blood. 2007;109(6):2356-2364. (Pubitemid 46425875)
    • (2007) Blood , vol.109 , Issue.6 , pp. 2356-2364
    • Vassen, L.1    Okayama, T.2    Moroy, T.3
  • 15
    • 70349850505 scopus 로고    scopus 로고
    • Gfi-1B promoter remains associated with active chromatin marks throughout erythroid differentiation of human primary progenitor cells
    • Laurent B, Randrianarison-Huetz V, Kadri Z, Romeo PH, Porteu F, Dumenil D. Gfi-1B promoter remains associated with active chromatin marks throughout erythroid differentiation of human primary progenitor cells. Stem Cells. 2009;27(9):2153-2162.
    • (2009) Stem Cells , vol.27 , Issue.9 , pp. 2153-2162
    • Laurent, B.1    Randrianarison-Huetz, V.2    Kadri, Z.3    Romeo, P.H.4    Porteu, F.5    Dumenil, D.6
  • 16
    • 34547785073 scopus 로고    scopus 로고
    • Epigenetic Regulation of Hematopoietic Differentiation by Gfi-1 and Gfi-1b Is Mediated by the Cofactors CoREST and LSD1
    • DOI 10.1016/j.molcel.2007.06.039, PII S1097276507004832
    • Saleque S, Kim J, Rooke HM, Orkin SH. Epigenetic regulation of hematopoietic differentiation by Gfi-1 and Gfi-1b is mediated by the cofactors CoREST and LSD1. Mol Cell. 2007;27(4):562-572. (Pubitemid 47238633)
    • (2007) Molecular Cell , vol.27 , Issue.4 , pp. 562-572
    • Saleque, S.1    Kim, J.2    Rooke, H.M.3    Orkin, S.H.4
  • 17
    • 33750322988 scopus 로고    scopus 로고
    • TGF-beta receptor-binding proteins: Complex interactions
    • Runyan CE, Poncelet AC, Schnaper HW. TGF-beta receptor-binding proteins: complex interactions. Cell Signal. 2006;18(12):2077-2088.
    • (2006) Cell Signal , vol.18 , Issue.12 , pp. 2077-2088
    • Runyan, C.E.1    Poncelet, A.C.2    Schnaper, H.W.3
  • 18
    • 0027276765 scopus 로고
    • Betaglycan presents ligand to the TGFbeta signaling receptor
    • DOI 10.1016/0092-8674(93)90368-Z
    • Lopez-Casillas F, Wrana JL, Massague J. Betaglycan presents ligand to the TGF beta signaling receptor. Cell. 1993;73(7):1435-1444. (Pubitemid 23201155)
    • (1993) Cell , vol.73 , Issue.7 , pp. 1435-1444
    • Lopez-Casillas, F.1    Wrana, J.L.2    Massague, J.3
  • 21
    • 58049195151 scopus 로고    scopus 로고
    • Endocytosis of the type III transforming growth factor-beta (TGF-beta) receptor through the clathrin-independent/lipid raft pathway regulates TGF-beta signaling and receptor down-regulation
    • Finger EC, Lee NY, You HJ, Blobe GC. Endocytosis of the type III transforming growth factor-beta (TGF-beta) receptor through the clathrin-independent/lipid raft pathway regulates TGF-beta signaling and receptor down-regulation. J Biol Chem. 2008;283(50):34808-34818.
    • (2008) J Biol Chem , vol.283 , Issue.50 , pp. 34808-34818
    • Finger, E.C.1    Lee, N.Y.2    You, H.J.3    Blobe, G.C.4
  • 22
    • 66249141288 scopus 로고    scopus 로고
    • The type III TGF-beta receptor regulates epithelial and cancer cell migration through beta-arrestin2-mediated activation of Cdc42
    • Mythreye K, Blobe GC. The type III TGF-beta receptor regulates epithelial and cancer cell migration through beta-arrestin2-mediated activation of Cdc42. Proc Natl Acad Sci U S A. 2009;106(20):8221-8226.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.20 , pp. 8221-8226
    • Mythreye, K.1    Blobe, G.C.2
  • 23
    • 36949015426 scopus 로고    scopus 로고
    • The type III TGF-beta receptor signals through both Smad3 and the p38 MAP kinase pathways to contribute to inhibition of cell proliferation
    • DOI 10.1093/carcin/bgm195
    • You HJ, Bruinsma MW, How T, Ostrander JH, Blobe GC. The type III TGF-beta receptor signals through both Smad3 and the p38 MAP kinase pathways to contribute to inhibition of cell proliferation. Carcinogenesis. 2007;28(12):2491-2500. (Pubitemid 350238951)
    • (2007) Carcinogenesis , vol.28 , Issue.12 , pp. 2491-2500
    • You, H.J.1    Bruinsma, M.W.2    How, T.3    Ostrander, J.H.4    Blobe, G.C.5
  • 24
    • 69449101160 scopus 로고    scopus 로고
    • The type III transforming growth factor-beta receptor negatively regulates nuclear factor kappa B signaling through its interaction with beta-arrestin2
    • You HJ, How T, Blobe GC. The type III transforming growth factor-beta receptor negatively regulates nuclear factor kappa B signaling through its interaction with beta-arrestin2. Carcinogenesis. 2009;30(8):1281-1287.
    • (2009) Carcinogenesis , vol.30 , Issue.8 , pp. 1281-1287
    • You, H.J.1    How, T.2    Blobe, G.C.3
  • 25
    • 35448946457 scopus 로고    scopus 로고
    • Coronary vessel development is dependent on the type III transforming growth factor beta receptor
    • DOI 10.1161/CIRCRESAHA.107.152082
    • Compton LA, Potash DA, Brown CB, Barnett JV. Coronary vessel development is dependent on the type III transforming growth factor beta receptor. Circ Res. 2007;101(8):784-791. (Pubitemid 350287193)
    • (2007) Circulation Research , vol.101 , Issue.8 , pp. 784-791
    • Compton, L.A.1    Potash, D.A.2    Brown, C.B.3    Barnett, J.V.4
  • 26
    • 0037979081 scopus 로고    scopus 로고
    • Heart and liver defects and reduced transforming growth factor beta2 sensitivity in transforming growth factor beta type III receptor-deficient embryos
    • Stenvers KL, Tursky ML, Harder KW, et al. Heart and liver defects and reduced transforming growth factor beta2 sensitivity in transforming growth factor beta type III receptor-deficient embryos. Mol Cell Biol. 2003;23(12):4371-4385.
    • (2003) Mol Cell Biol , vol.23 , Issue.12 , pp. 4371-4385
    • Stenvers, K.L.1    Tursky, M.L.2    Harder, K.W.3
  • 27
    • 33646876973 scopus 로고    scopus 로고
    • Hematopoiesis Controlled by Distinct TIF1gamma and Smad4 Branches of the TGFbeta Pathway
    • DOI 10.1016/j.cell.2006.03.045, PII S0092867406005186
    • He W, Dorn DC, Erdjument-Bromage H, Tempst P, Moore MA, Massague J. Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway. Cell. 2006;125(5):929-941. (Pubitemid 43795187)
    • (2006) Cell , vol.125 , Issue.5 , pp. 929-941
    • He, W.1    Dorn, D.C.2    Erdjument-Bromage, H.3    Tempst, P.4    Moore, M.A.S.5    Massague, J.6
  • 31
    • 0025363266 scopus 로고
    • Induced differentiation of K562 leukemia cells: A model for studies of gene expression in early megakaryoblasts
    • DOI 10.1016/0145-2126(90)90002-Q
    • Alitalo R. Induced differentiation of K562 leukemia cells: a model for studies of gene expression in early megakaryoblasts. Leuk Res. 1990;14(6):501-514. (Pubitemid 20213713)
    • (1990) Leukemia Research , vol.14 , Issue.6 , pp. 501-514
    • Alitalo, R.1
  • 32
    • 0024455089 scopus 로고
    • Effect of transforming growth factor-beta1 on proliferation and induction of hemoglobin accumulation in K-562 cells
    • Chen LL, Dean A, Jenkinson T, Mendelsohn J. Effect of transforming growth factor-beta 1 on proliferation and induction of hemoglobin accumulation in K-562 cells. Blood. 1989;74(7):2368-2375. (Pubitemid 19286454)
    • (1989) Blood , vol.74 , Issue.7 , pp. 2368-2375
    • Chen, L.L.1    Dean, A.2    Jenkinson, T.3    Mendelsohn, J.4
  • 33
    • 33645766023 scopus 로고    scopus 로고
    • Gfi1 and Gfi1b act equivalently in haematopoiesis, but have distinct, non-overlapping functions in inner ear development
    • Fiolka K, Hertzano R, Vassen L, et al. Gfi1 and Gfi1b act equivalently in haematopoiesis, but have distinct, non-overlapping functions in inner ear development. EMBO Rep. 2006;7(3):326-333.
    • (2006) EMBO Rep , vol.7 , Issue.3 , pp. 326-333
    • Fiolka, K.1    Hertzano, R.2    Vassen, L.3
  • 34
    • 0034329453 scopus 로고    scopus 로고
    • The zinc finger protein Gfi-1 can enhance STAT3 signaling by interacting with the STAT3 inhibitor PIAS3
    • Rodel B, Tavassoli K, Karsunky H, et al. The zinc finger protein Gfi-1 can enhance STAT3 signaling by interacting with the STAT3 inhibitor PIAS3. EMBO J. 2000;19(21):5845-5855.
    • (2000) EMBO J , vol.19 , Issue.21 , pp. 5845-5855
    • Rodel, B.1    Tavassoli, K.2    Karsunky, H.3
  • 35
    • 27644494876 scopus 로고    scopus 로고
    • Smad transcription factors
    • Massague J, Seoane J, Wotton D. Smad transcription factors. Genes Dev. 2005;19(23):2783-2810.
    • (2005) Genes Dev , vol.19 , Issue.23 , pp. 2783-2810
    • Massague, J.1    Seoane, J.2    Wotton, D.3
  • 36
    • 33745082823 scopus 로고    scopus 로고
    • Role of transforming growth factor-beta in hematologic malignancies
    • DOI 10.1182/blood-2005-10-4169
    • Dong M, Blobe GC. Role of transforming growth factor-beta in hematologic malignancies. Blood. 2006;107(12):4589-4596. (Pubitemid 43882602)
    • (2006) Blood , vol.107 , Issue.12 , pp. 4589-4596
    • Dong, M.1    Blobe, G.C.2
  • 38
    • 53149103582 scopus 로고    scopus 로고
    • Smad-independent transforming growth factor-beta regulation of early growth response-1 and sustained expression in fibrosis: Implications for scleroderma
    • Bhattacharyya S, Chen SJ, Wu M, et al. Smad-independent transforming growth factor-beta regulation of early growth response-1 and sustained expression in fibrosis: implications for scleroderma. Am J Pathol. 2008;173(4):1085-1099.
    • (2008) Am J Pathol , vol.173 , Issue.4 , pp. 1085-1099
    • Bhattacharyya, S.1    Chen, S.J.2    Wu, M.3
  • 39
    • 24944497786 scopus 로고    scopus 로고
    • Non-Smad TGF-beta signals
    • Moustakas A, Heldin CH. Non-Smad TGF-beta signals. J Cell Sci. 2005;118(16):3573-3584.
    • (2005) J Cell Sci , vol.118 , Issue.16 , pp. 3573-3584
    • Moustakas, A.1    Heldin, C.H.2
  • 40
    • 0034704753 scopus 로고    scopus 로고
    • Betaglycan binds inhibin and can mediate functional antagonism of activin signalling
    • Lewis KA, Gray PC, Blount AL, et al. Betaglycan binds inhibin and can mediate functional antagonism of activin signalling. Nature. 2000;404(6776):411-414.
    • (2000) Nature , vol.404 , Issue.6776 , pp. 411-414
    • Lewis, K.A.1    Gray, P.C.2    Blount, A.L.3
  • 41
    • 43149095145 scopus 로고    scopus 로고
    • Bone morphogenetic proteins signal through the transforming growth factor-beta type III receptor
    • Kirkbride KC, Townsend TA, Bruinsma MW, Barnett JV, Blobe GC. Bone morphogenetic proteins signal through the transforming growth factor-beta type III receptor. J Biol Chem. 2008;283(12):7628-7637.
    • (2008) J Biol Chem , vol.283 , Issue.12 , pp. 7628-7637
    • Kirkbride, K.C.1    Townsend, T.A.2    Bruinsma, M.W.3    Barnett, J.V.4    Blobe, G.C.5
  • 42
    • 0037424231 scopus 로고    scopus 로고
    • Inhibin is an antagonist of bone morphogenetic protein signaling
    • DOI 10.1074/jbc.M209710200
    • Wiater E, Vale W. Inhibin is an antagonist of bone morphogenetic protein signaling. J Biol Chem. 2003;278(10):7934-7941. (Pubitemid 36800530)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.10 , pp. 7934-7941
    • Wiater, E.1    Vale, W.2
  • 43
    • 70350088248 scopus 로고    scopus 로고
    • The transforming growth factor-beta type III receptor mediates distinct subcellular trafficking and downstream signaling of activin-like kinase (ALK)3 and ALK6 receptors
    • Lee NY, Kirkbride KC, Sheu RD, Blobe GC. The transforming growth factor-beta type III receptor mediates distinct subcellular trafficking and downstream signaling of activin-like kinase (ALK)3 and ALK6 receptors. Mol Biol Cell. 2009;20(20):4362-4370.
    • (2009) Mol Biol Cell , vol.20 , Issue.20 , pp. 4362-4370
    • Lee, N.Y.1    Kirkbride, K.C.2    Sheu, R.D.3    Blobe, G.C.4


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