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Volumn 471, Issue 1-2, 2014, Pages 498-506

Oral transmucosal drug delivery - Current status and future prospects

Author keywords

Buccal; Formulations; Models; Oral transmucosal drug delivery; Sublingual

Indexed keywords

ACICLOVIR; ASENAPINE; ATENOLOL; BUPIVACAINE; BUPRENORPHINE; BUSPIRONE; CARBAMAZEPINE; CELECOXIB; CHLORPHENIRAMINE MALEATE; DICLOFENAC; DIDANOSINE; DIETHYLENE GLYCOL MONOETHYL ETHER; DILTIAZEM; DOMPERIDONE; ENDOMORPHIN 1; FENTANYL; FENTANYL CITRATE; GALANTAMINE; GLYCERYL TRINITRATE; MACROGOL 400; MACROGOL DERIVATIVE; METOPROLOL; MIDAZOLAM; NALOXONE; NICOTINE; NIMESULIDE; PHENAZONE; PROCHLORPERAZINE MALEATE; TESTOSTERONE; UNINDEXED DRUG; DRUG;

EID: 84902668945     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.05.043     Document Type: Review
Times cited : (123)

References (113)
  • 1
    • 77952888510 scopus 로고    scopus 로고
    • Construction and in vitro characterization of an optimized porosity-enabled amalgamated matrix for sustained transbuccal drug delivery
    • O.A. Adeleke, V. Pillay, and Y.E. du Toit Construction and in vitro characterization of an optimized porosity-enabled amalgamated matrix for sustained transbuccal drug delivery Int. J. Pharm. 391 2010 79 89
    • (2010) Int. J. Pharm. , vol.391 , pp. 79-89
    • Adeleke, O.A.1    Pillay, V.2    Du Toit, Y.E.3
  • 3
    • 84899584145 scopus 로고    scopus 로고
    • A comparative ex vivo drug permeation study of beta-blockers through porcine buccal mucosa
    • S. Amores, J. Lauroba, A. Calpena, H. Colom, A. Gimeno, and J. Domenech A comparative ex vivo drug permeation study of beta-blockers through porcine buccal mucosa Int. J. Pharm. 468 2014 50 54
    • (2014) Int. J. Pharm. , vol.468 , pp. 50-54
    • Amores, S.1    Lauroba, J.2    Calpena, A.3    Colom, H.4    Gimeno, A.5    Domenech, J.6
  • 4
    • 0037413398 scopus 로고    scopus 로고
    • Buccal delivery of thiocolchicoside: In vitro and in vivo permeation studies
    • DOI 10.1016/S0378-5173(02)00545-8, PII S0378517302005458
    • M. Artusi, P. Santi, P. Colombo, and H.E. Junginger Buccal delivery of thiocolchicoside: in vitro and in vivo permeation studies Int. J. Pharm. 250 2003 203 213 (Pubitemid 35447950)
    • (2003) International Journal of Pharmaceutics , vol.250 , Issue.1 , pp. 203-213
    • Artusi, M.1    Santi, P.2    Colombo, P.3    Junginger, H.E.4
  • 5
    • 84868334616 scopus 로고    scopus 로고
    • Development and evaluation of tamarind seed xyloglucan-based mucoadhesive buccal films of rizatriptan benzoate
    • A.M. Avachat, K.N. Gujar, and K.V. Wagh Development and evaluation of tamarind seed xyloglucan-based mucoadhesive buccal films of rizatriptan benzoate Carbohydr. Polym. 91 2013 537 542
    • (2013) Carbohydr. Polym. , vol.91 , pp. 537-542
    • Avachat, A.M.1    Gujar, K.N.2    Wagh, K.V.3
  • 6
    • 0014180903 scopus 로고
    • Buccal absorption of basic drugs and its application as an in vivo model of passive drug transfer through lipid membranes
    • A.H. Beckett, and E.J. Triggs Buccal absorption of basic drugs and its application as an in vivo model of passive drug transfer through lipid membranes J. Pharm. Pharmacol. 19 1967 31S 41S
    • (1967) J. Pharm. Pharmacol. , vol.19
    • Beckett, A.H.1    Triggs, E.J.2
  • 7
    • 0014370772 scopus 로고
    • The influence of alkyl substitution in acids on their performance in the buccal absorption test
    • A.H. Beckett, and A.C. Moffat The influence of alkyl substitution in acids on their performance in the buccal absorption test J. Pharm. Pharmacol. 20 1968 239S 247S
    • (1968) J. Pharm. Pharmacol. , vol.20
    • Beckett, A.H.1    Moffat, A.C.2
  • 8
    • 0014619329 scopus 로고
    • The influence of substitution in phenylacetic acids on their performance in the buccal absorption test
    • A.H. Beckett, and A.C. Moffat The influence of substitution in phenylacetic acids on their performance in the buccal absorption test J. Pharm. Pharmacol. 21 1969 139S 143S
    • (1969) J. Pharm. Pharmacol. , vol.21
    • Beckett, A.H.1    Moffat, A.C.2
  • 9
    • 0014644381 scopus 로고
    • Correlation of partition coefficients in Il-heptane-aqueous systems with buccal absorption data for a series of amines and acids
    • A.H. Beckett, and A.C. Moffat Correlation of partition coefficients in Il-heptane-aqueous systems with buccal absorption data for a series of amines and acids J. Pharm. Pharmacol. 21 1969 144S 150S
    • (1969) J. Pharm. Pharmacol. , vol.21
    • Beckett, A.H.1    Moffat, A.C.2
  • 10
    • 0014703581 scopus 로고
    • Kinetics of buccal absorption of some carboxylic acids and the correlation of the rate constants and n-heptane: Aqueous phase partition coefficients
    • A.H. Beckett, and A.C. Moffat Kinetics of buccal absorption of some carboxylic acids and the correlation of the rate constants and n-heptane: aqueous phase partition coefficients J. Pharm. Pharmacol. 22 1970 15 19
    • (1970) J. Pharm. Pharmacol. , vol.22 , pp. 15-19
    • Beckett, A.H.1    Moffat, A.C.2
  • 11
    • 0014984229 scopus 로고
    • The buccal absorption of some barbiturates
    • A.H. Beckett, and A.C. Moffat The buccal absorption of some barbiturates J. Pharm. Pharmacol. 23 1971 15 18
    • (1971) J. Pharm. Pharmacol. , vol.23 , pp. 15-18
    • Beckett, A.H.1    Moffat, A.C.2
  • 12
    • 0016821644 scopus 로고
    • A model for steroid transport across biological membranes
    • A.H. Beckett, and M.E. Pickup A model for steroid transport across biological membranes J. Pharm. Pharmacol. 27 1975 226 234
    • (1975) J. Pharm. Pharmacol. , vol.27 , pp. 226-234
    • Beckett, A.H.1    Pickup, M.E.2
  • 13
    • 0035907175 scopus 로고    scopus 로고
    • Transbuccal peptide delivery: Stability and in vitro permeation studies on endomorphin-1
    • DOI 10.1016/S0168-3659(01)00246-2, PII S0168365901002462
    • A.P. Bird, J.R. Faltinek, and A.H. Shojaei Transbuccal peptide delivery: stability and in vitro permeation studies on endomorphin-1 J. Control. Release 73 2001 31 36 (Pubitemid 32406099)
    • (2001) Journal of Controlled Release , vol.73 , Issue.1 , pp. 31-36
    • Bird, A.P.1    Faltinek, J.R.2    Shojaei, A.H.3
  • 14
    • 12244305575 scopus 로고    scopus 로고
    • Buccal permeation of buspirone: Mechanistic studies on transport pathways
    • DOI 10.1002/jps.20208
    • R. Birudaraj, B. Berner, S. Shen, and X. Li Buccal permeation of buspirone: mechanistic studies on transport pathways J. Pharm. Sci. 94 2005 70 78 (Pubitemid 40116371)
    • (2005) Journal of Pharmaceutical Sciences , vol.94 , Issue.1 , pp. 70-78
    • Birudaraj, R.1    Berner, B.2    Shen, S.3    Li, X.4
  • 15
    • 77954310097 scopus 로고    scopus 로고
    • Bioavailability in vivo of naltrexone following transbuccal administration by an electronically-controlled intraoral device: A trial on pigs
    • G. Campisi, L.I. Giannola, A.M. Florena, V. De Caro, A. Schumacher, T. Gottsche, C. Paderni, and A. Wolff Bioavailability in vivo of naltrexone following transbuccal administration by an electronically-controlled intraoral device: a trial on pigs J. Control. Release 145 2010 214 220
    • (2010) J. Control. Release , vol.145 , pp. 214-220
    • Campisi, G.1    Giannola, L.I.2    Florena, A.M.3    De Caro, V.4    Schumacher, A.5    Gottsche, T.6    Paderni, C.7    Wolff, A.8
  • 16
    • 84901281018 scopus 로고    scopus 로고
    • Exploiting the buccal mucosa as an alternative route for the delivery of donepezil hydrochloride
    • T. Caon, Y. Pan, C.M. Simoes, and J.A. Nicolazzo Exploiting the buccal mucosa as an alternative route for the delivery of donepezil hydrochloride J. Pharm. Sci. 103 2014 1643 1651
    • (2014) J. Pharm. Sci. , vol.103 , pp. 1643-1651
    • Caon, T.1    Pan, Y.2    Simoes, C.M.3    Nicolazzo, J.A.4
  • 17
    • 33746047742 scopus 로고    scopus 로고
    • Cyclodextrin-containing poly(ethyleneoxide) tablets for the delivery of poorly soluble drugs: Potential as buccal delivery system
    • DOI 10.1016/j.ijpharm.2006.03.031, PII S0378517306002687
    • B. Cappello, G. De Rosa, L. Giannini, M.I. La Rotonda, G. Mensitieri, A. Miro, F. Quaglia, and R. Russo Cyclodextrin-containing poly(ethyleneoxide) tablets for the delivery of poorly soluble drugs: potential as buccal delivery system Int. J. Pharm. 319 2006 63 70 (Pubitemid 44069630)
    • (2006) International Journal of Pharmaceutics , vol.319 , Issue.1-2 , pp. 63-70
    • Cappello, B.1    De Rosa, G.2    Giannini, L.3    La Rotonda, M.I.4    Mensitieri, G.5    Miro, A.6    Quaglia, F.7    Russo, R.8
  • 18
    • 44849135551 scopus 로고    scopus 로고
    • Development and evaluation of buccoadhesive controlled release tablets of lercanidipine
    • S. Charde, M. Mudgal, L. Kumar, and R. Saha Development and evaluation of buccoadhesive controlled release tablets of lercanidipine AAPS PharmSciTech 9 2008 182 190
    • (2008) AAPS PharmSciTech , vol.9 , pp. 182-190
    • Charde, S.1    Mudgal, M.2    Kumar, L.3    Saha, R.4
  • 19
    • 84861092301 scopus 로고    scopus 로고
    • In vitro characterization of chitosan gels for buccal delivery of celecoxib: Influence of a penetration enhancer
    • Y.P. Cid, V. Pedrazzi, V.P. de Sousa, and M.B. Pierre In vitro characterization of chitosan gels for buccal delivery of celecoxib: influence of a penetration enhancer AAPS PharmSciTech. 13 2012 101 111
    • (2012) AAPS PharmSciTech. , vol.13 , pp. 101-111
    • Cid, Y.P.1    Pedrazzi, V.2    De Sousa, V.P.3    Pierre, M.B.4
  • 20
    • 33845304731 scopus 로고    scopus 로고
    • Rise of testosterone, nortestosterone, and 17ß-estradiol concentrations in peripheral blood plasma of pigs after sublingual application in vivo
    • DOI 10.1016/j.fct.2006.08.003, PII S0278691506002316
    • R. Claus, S. Haussler, and M. Lacorn Rise of testosterone, nortestosterone, and 17beta-estradiol concentrations in peripheral blood plasma of pigs after sublingual application in vivo Food Chem. Toxicol. 45 2007 225 228 (Pubitemid 44872913)
    • (2007) Food and Chemical Toxicology , vol.45 , Issue.2 , pp. 225-228
    • Claus, R.1    Haussler, S.2    Lacorn, M.3
  • 21
  • 22
    • 84859977179 scopus 로고    scopus 로고
    • Statistical optimization of insulin-loaded Pluronic F-127 gels for buccal delivery of basal insulin
    • N. Das, P. Madan, and S. Lin Statistical optimization of insulin-loaded Pluronic F-127 gels for buccal delivery of basal insulin Pharm. Dev. Technol. 17 2012 363 374
    • (2012) Pharm. Dev. Technol. , vol.17 , pp. 363-374
    • Das, N.1    Madan, P.2    Lin, S.3
  • 24
    • 54949136459 scopus 로고    scopus 로고
    • Evaluation of galantaminetransbuccal absorption by reconstituted human oral epithelium andporcine tissue as buccal mucosa models: Part i
    • V. De Caro, G. Giandalia, M.G. Siragusa, C. Paderni, G. Campisi, and L.I. Giannola Evaluation of galantaminetransbuccal absorption by reconstituted human oral epithelium andporcine tissue as buccal mucosa models: part I Eur. J. Pharm. Biopharm. 70 2008 869 873
    • (2008) Eur. J. Pharm. Biopharm. , vol.70 , pp. 869-873
    • De Caro, V.1    Giandalia, G.2    Siragusa, M.G.3    Paderni, C.4    Campisi, G.5    Giannola, L.I.6
  • 25
    • 84859599368 scopus 로고    scopus 로고
    • New prospective in treatment of Parkinson's disease: Studies on permeation of ropinirolethroughbuccal mucosa
    • V. De Caro, G. Giandalia, M.G. Siragua, F.M. Sutera, and L.I. Giannola New prospective in treatment of Parkinson's disease: studies on permeation of ropinirolethroughbuccal mucosa Int. J. Pharm. 429 2012 78 83
    • (2012) Int. J. Pharm. , vol.429 , pp. 78-83
    • De Caro, V.1    Giandalia, G.2    Siragua, M.G.3    Sutera, F.M.4    Giannola, L.I.5
  • 27
    • 24044463565 scopus 로고    scopus 로고
    • Transport of fentanyl through pig buccal and esophageal epithelia in vitro. Influence of concentration and vehicle pH
    • DOI 10.1007/s11095-005-6020-y
    • I. Diaz Del Consuelo, F. Falson, R.H. Guy, and Y. Jacques Transport of fentanyl through pig buccal and esophageal epithelia in vitro: influence of concentration and vehicle pH Pharm. Res. 22 2005 1525 1529 (Pubitemid 41215893)
    • (2005) Pharmaceutical Research , vol.22 , Issue.9 , pp. 1525-1529
    • Diaz Del Consuelo, I.1    Falson, F.2    Guy, R.H.3    Jacques, Y.4
  • 28
    • 70349087316 scopus 로고    scopus 로고
    • Oral strip technology: Overview and future potential
    • R.P. Dixit, and S.P. Puthli Oral strip technology: overview and future potential J. Control. Release 139 2009 94 107
    • (2009) J. Control. Release , vol.139 , pp. 94-107
    • Dixit, R.P.1    Puthli, S.P.2
  • 29
    • 6944237664 scopus 로고    scopus 로고
    • Formulation and evaluation of diclofenac sodium buccoadhesive discs
    • DOI 10.1016/j.ijpharm.2004.07.033, PII S0378517304004806
    • M.S. El-Samaligy, S.A. Yahia, and E.B. Basalious Formulation and evaluation of diclofenac sodium buccoadhesive discs Int. J. Pharm. 286 2004 27 39 (Pubitemid 39410471)
    • (2004) International Journal of Pharmaceutics , vol.286 , Issue.1-2 , pp. 27-39
    • El-Samaligy, M.S.1    Yahia, S.A.2    Basalious, E.B.3
  • 30
    • 59649115338 scopus 로고    scopus 로고
    • In vitro evaluation of natural and methylated cyclodextrins as buccal permeation enhancing system for omeprazole delivery
    • A. Figueiras, J. Hornbach, F. Veiga, and A. Bernkop-Schnürch In vitro evaluation of natural and methylated cyclodextrins as buccal permeation enhancing system for omeprazole delivery Eur. J. Pharm. Biopharm. 71 2009 339 345
    • (2009) Eur. J. Pharm. Biopharm. , vol.71 , pp. 339-345
    • Figueiras, A.1    Hornbach, J.2    Veiga, F.3    Bernkop-Schnürch, A.4
  • 31
    • 0028123427 scopus 로고
    • Oral cavity as a site for bioadhesive drug delivery
    • R.B. Gandhi, and J.R. Robinson Oral cavity as a site for bioadhesive drug delivery Adv. Drug Deliv. Rev. 13 1994 43 74 (Pubitemid 24032041)
    • (1994) Advanced Drug Delivery Reviews , vol.13 , Issue.1-2 , pp. 43-74
    • Gandhi, R.B.1    Robinson, J.R.2
  • 34
    • 77950267129 scopus 로고    scopus 로고
    • New prospectives in the delivery ofgalantamine for elderly patients using the IntelliDrug intraoral device: In vivo animal studies
    • L.I. Giannola, C. Paderni, V. De Caro, A.M. Florena, A. Wolff, and G. Campisi New prospectives in the delivery ofgalantamine for elderly patients using the IntelliDrug intraoral device: in vivo animal studies Curr. Pharm. Design 16 2010 653 659
    • (2010) Curr. Pharm. Design , vol.16 , pp. 653-659
    • Giannola, L.I.1    Paderni, C.2    De Caro, V.3    Florena, A.M.4    Wolff, A.5    Campisi, G.6
  • 35
    • 0006367023 scopus 로고    scopus 로고
    • Systemic oral mucosal drug delivery systems and delivery systems
    • M.J. Rathbone, Marcel Dekker Inc. New York
    • P. Gilles, and F.A. Ghazali Systemic oral mucosal drug delivery systems and delivery systems M.J. Rathbone, Oral Mucosal Drug Delivery 1996 Marcel Dekker Inc. New York 241 285
    • (1996) Oral Mucosal Drug Delivery , pp. 241-285
    • Gilles, P.1    Ghazali, F.A.2
  • 36
    • 0031901774 scopus 로고    scopus 로고
    • Comparative biomembrane permeation of tacrine using Yucatan minipigs and domestic pigs as the animal model
    • DOI 10.1021/js970359u
    • A.V. Gore, A.C. Liang, and Y.W. Chien Comparative biomembrane permeation of tacrine using Yucatan minipigs and domestic pigs as the animal model J. Pharm. Sci. 87 1998 441 447 (Pubitemid 28175804)
    • (1998) Journal of Pharmaceutical Sciences , vol.87 , Issue.4 , pp. 441-447
    • Gore, A.V.1    Liang, A.C.2    Chien, Y.W.3
  • 37
    • 67349248559 scopus 로고    scopus 로고
    • Estimation of the theoretical pore sizes of the porcine oral mucosa for permeation of hydrophilic permeants
    • T. Goswami, B.R. Jasti, and X. Li Estimation of the theoretical pore sizes of the porcine oral mucosa for permeation of hydrophilic permeants Arch. Oral Biol. 54 2009 577 578
    • (2009) Arch. Oral Biol. , vol.54 , pp. 577-578
    • Goswami, T.1    Jasti, B.R.2    Li, X.3
  • 38
    • 84876020270 scopus 로고    scopus 로고
    • In silico model of drug permeability across sublingual mucosa
    • T. Goswami, A. Kokate, B.R. Jasti, and X. Li In silico model of drug permeability across sublingual mucosa Arch. Oral Biol. 58 2013 545 551
    • (2013) Arch. Oral Biol. , vol.58 , pp. 545-551
    • Goswami, T.1    Kokate, A.2    Jasti, B.R.3    Li, X.4
  • 39
    • 0026564618 scopus 로고
    • Drug delivery via the mucous membranes of the oral cavity
    • D. Harris, and J.R. Robinson Drug delivery via the mucous membranes of the oral cavity J. Pharm. Sci. 81 1992 1 10
    • (1992) J. Pharm. Sci. , vol.81 , pp. 1-10
    • Harris, D.1    Robinson, J.R.2
  • 40
    • 0018122725 scopus 로고
    • Histological investigation of the influence of adult porcine alveolar mucosal connective tissues on epithelial differentiation
    • T.G. Heaney, and R.S. Jones Histological investigation of the influence of adult porcine alveolar mucosal connective tissue on epithelial differentiation Arch. Oral Biol. 23 1978 713 717 (Pubitemid 9031790)
    • (1978) Archives of Oral Biology , vol.23 , Issue.8 , pp. 713-717
    • Heaney, T.G.1    Jones, R.S.2
  • 41
    • 78149339756 scopus 로고    scopus 로고
    • The buccal mucosa as an alternative route for the systemic delivery of risperidone
    • L.B. Heemstra, B.C. Finnin, and J.A. Nicolazzo The buccal mucosa as an alternative route for the systemic delivery of risperidone J. Pharm. Sci. 99 2010 4584 4592
    • (2010) J. Pharm. Sci. , vol.99 , pp. 4584-4592
    • Heemstra, L.B.1    Finnin, B.C.2    Nicolazzo, J.A.3
  • 43
    • 84875304967 scopus 로고    scopus 로고
    • In vitro, ex vivo and in vivo examination of buccal absorption of metoprolol with varying pH inTR146 cell culture, porcine buccal mucosa and Gøttingen minipigs
    • R. Holm, E. Meng-Lund, M.B. Andersen, M.L. Jespersen, J.J. Karlsson, M. Garmer, E.B. Jørgensen, and J. Jacobsen In vitro, ex vivo and in vivo examination of buccal absorption of metoprolol with varying pH inTR146 cell culture, porcine buccal mucosa and Gøttingen minipigs Eur. J. Pharm. Sci. 49 2013 117 124
    • (2013) Eur. J. Pharm. Sci. , vol.49 , pp. 117-124
    • Holm, R.1    Meng-Lund, E.2    Andersen, M.B.3    Jespersen, M.L.4    Karlsson, J.J.5    Garmer, M.6    Jørgensen, E.B.7    Jacobsen, J.8
  • 44
    • 0027972453 scopus 로고
    • Diffusion rates and transport pathways of fluorescein isothiocyanate (FITC)-labeled model compounds through buccal epithelium
    • DOI 10.1023/A:1018949828548
    • C. Hoogstraate, J.F. Nagelkerke, S. Senel, J.C. Verhoef, H.E. Junginger, and H.E. Bodde Diffusion rates and transport pathways offluorescein isothiocyanate (FITC)-labeled model compounds through buccal epithelium Pharm. Res. 11 1994 83 89 (Pubitemid 24040768)
    • (1994) Pharmaceutical Research , vol.11 , Issue.1 , pp. 83-89
    • Hoogstraate, A.J.1    Cullander, C.2    Nagelkerke, J.F.3    Senel, S.4    Verhoef, J.C.5    Junginger, H.E.6    Bodde, H.E.7
  • 46
    • 81155122915 scopus 로고    scopus 로고
    • Transdermal and transbuccal drug delivery systems: Enhancement using iontophoretic and chemical approaches
    • L. Hu, S.M. Silva, B.B. Damaj, R. Martin, and B.B. Michniak-Kohn Transdermal and transbuccal drug delivery systems: enhancement using iontophoretic and chemical approaches Int. J. Pharm. 421 2011 53 62
    • (2011) Int. J. Pharm. , vol.421 , pp. 53-62
    • Hu, L.1    Silva, S.M.2    Damaj, B.B.3    Martin, R.4    Michniak-Kohn, B.B.5
  • 47
    • 0035966522 scopus 로고    scopus 로고
    • Buccal iontophoretic delivery of atenolol·HCl employing a new in vitro three-chamber permeation cell
    • DOI 10.1016/S0168-3659(00)00328-X, PII S016836590000328X
    • J. Jacobsen Buccal iontophoretic delivery of atenolol. HCl employing a new in vitro three-chamber permeation cell J. Control. Release 70 2001 83 95 (Pubitemid 32144795)
    • (2001) Journal of Controlled Release , vol.70 , Issue.1-2 , pp. 83-95
    • Jacobsen, J.1
  • 49
    • 39449139281 scopus 로고    scopus 로고
    • Design and development of a mucoadhesive buccal film bearing progesterone
    • DOI 10.1691/ph.2008.7114
    • S.K. Jain, A. Jain, Y. Gupta, and A. Kharya Design and development of a mucoadhesive buccal film bearing progesterone Pharmazie 63 2008 129 135 (Pubitemid 351270883)
    • (2008) Pharmazie , vol.63 , Issue.2 , pp. 129-135
    • Jain, S.K.1    Jain, A.2    Gupta, Y.3    Kharya, A.4
  • 50
    • 84857574189 scopus 로고    scopus 로고
    • Double-phase hydrogel for buccal delivery of tramadol
    • R. Kamel, A. Mahmoud, and G. El-Feky Double-phase hydrogel for buccal delivery of tramadol Drug Dev. Ind. Pharm. 38 2012 468 483
    • (2012) Drug Dev. Ind. Pharm. , vol.38 , pp. 468-483
    • Kamel, R.1    Mahmoud, A.2    El-Feky, G.3
  • 51
    • 53849141376 scopus 로고    scopus 로고
    • Effect of thermodynamic activities of the unionized and ionized species on drug flux across buccal mucosa
    • A. Kokate, X. Li, P. Singh, and B.R. Jasti Effect of thermodynamic activities of the unionized and ionized species on drug flux across buccal mucosa J. Pharm. Sci. 97 2008 4294 4306
    • (2008) J. Pharm. Sci. , vol.97 , pp. 4294-4306
    • Kokate, A.1    Li, X.2    Singh, P.3    Jasti, B.R.4
  • 52
    • 51449091366 scopus 로고    scopus 로고
    • Effect of drug lipophilicity and ionization on permeability across the buccal mucosa: A technical note
    • A. Kokate, X. Li, and B. Jasti Effect of drug lipophilicity and ionization on permeability across the buccal mucosa: a technical note AAPS PharmSciTech 9 2008 501 504
    • (2008) AAPS PharmSciTech , vol.9 , pp. 501-504
    • Kokate, A.1    Li, X.2    Jasti, B.3
  • 53
    • 63949085325 scopus 로고    scopus 로고
    • In silico prediction of drug permeability across buccal mucosa
    • A. Kokate, X. Li, P.J. Williams, P. Singh, and B.R. Jasti In silico prediction of drug permeability across buccal mucosa Pharm. Res. 26 2009 1130 1139
    • (2009) Pharm. Res. , vol.26 , pp. 1130-1139
    • Kokate, A.1    Li, X.2    Williams, P.J.3    Singh, P.4    Jasti, B.R.5
  • 54
    • 59849098596 scopus 로고    scopus 로고
    • Porcine buccal mucosa as an in vitro model: Relative contribution of epithelium and connective tissue as permeability barriers
    • U. Kulkarni, R. Mahalinghan, S.I. Pather, and B. Jasti Porcine buccal mucosa as an in vitro model: relative contribution of epithelium and connective tissue as permeability barriers J. Pharm. Sci. 98 2009 471 483
    • (2009) J. Pharm. Sci. , vol.98 , pp. 471-483
    • Kulkarni, U.1    Mahalinghan, R.2    Pather, S.I.3    Jasti, B.4
  • 55
    • 76649101750 scopus 로고    scopus 로고
    • Porcine buccal mucosa as in vitro model: Effect of biological and experimental variables
    • U. Kulkarni, R. Mahalingam, I. Pather, X. Li, and B. Jasti Porcine buccal mucosa as in vitro model: effect of biological and experimental variables J. Pharm. Sci. 99 2010 1265 1277
    • (2010) J. Pharm. Sci. , vol.99 , pp. 1265-1277
    • Kulkarni, U.1    Mahalingam, R.2    Pather, I.3    Li, X.4    Jasti, B.5
  • 56
    • 85027947702 scopus 로고    scopus 로고
    • Effect of experimental temperature on the permeation of model diffusants across porcine buccalmucosa
    • U.D. Kulkarni, R. Mahalingam, X.X. Li, I. Pather, and B. Jasti Effect of experimental temperature on the permeation of model diffusants across porcine buccalmucosa AAPS PharmSciTech 12 2011 579 586
    • (2011) AAPS PharmSciTech , vol.12 , pp. 579-586
    • Kulkarni, U.D.1    Mahalingam, R.2    Li, X.X.3    Pather, I.4    Jasti, B.5
  • 57
    • 0026719630 scopus 로고
    • Existence of a specialized absorption mechanism for cefadroxil, an aminocephalosporin antibiotic, in the human oral cavity
    • Y. Kurosaki, H. Nishimura, K. Terao, T. Nakayama, and T. Kimura Existence of a specialized absorption mechanism for cefadroxil, an aminocephalosporin antibiotic, in the human oral cavity Int. J. Pharm. 82 1992 165 169
    • (1992) Int. J. Pharm. , vol.82 , pp. 165-169
    • Kurosaki, Y.1    Nishimura, H.2    Terao, K.3    Nakayama, T.4    Kimura, T.5
  • 58
    • 0031969413 scopus 로고    scopus 로고
    • Perfusion cells for studying regional variation in oral mucosal permeability in humans. 2. A specialized transport mechanism in D-glucose absorption exists in dorsum of tongue
    • DOI 10.1021/js9703028
    • Y. Kurosaki, K. Yano, and T. Kimura Perfusion cells for studying regional variation in oral mucosal permeability in humans. 2. A specialized transport mechanism in d-glucose absorption exists in dorsum of tongue J. Pharm. Sci. 87 1998 613 615 (Pubitemid 28225627)
    • (1998) Journal of Pharmaceutical Sciences , vol.87 , Issue.5 , pp. 613-615
    • Kurosaki, Y.1    Yano, K.2    Kimura, T.3
  • 59
    • 18844369290 scopus 로고    scopus 로고
    • Development of a mucoadhesive and permeation enhancing buccal delivery system for PACAP (pituitary adenylate cyclase-activating polypeptide)
    • DOI 10.1016/j.ijpharm.2005.03.007, PII S0378517305001596
    • N. Langoth, J. Kalbe, and A. Bernkop-Schnürch Development of a mucoadhesive and permeation enhancing buccal delivery system for PACAP (pituitary adenylate cyclase-activating polypeptide) Int. J. Pharm. 296 2005 103 111 (Pubitemid 40693378)
    • (2005) International Journal of Pharmaceutics , vol.296 , Issue.1-2 , pp. 103-111
    • Langoth, N.1    Kalbe, J.2    Bernkop-Schnurch, A.3
  • 60
    • 0034690936 scopus 로고    scopus 로고
    • Combined effect of oleic acid and polyethylene glycol 200 on buccal permeation of [d-ala2, d-leu5]enkephalin from a cubic phase of glyceryl monooleate
    • J. Lee, and I.W. Kellaway Combined effect of oleic acid and polyethylene glycol 200 on buccal permeation of [d-ala2, d-leu5]enkephalin from a cubic phase of glyceryl monooleate Int. J. Pharm. 204 2000 137 144
    • (2000) Int. J. Pharm. , vol.204 , pp. 137-144
    • Lee, J.1    Kellaway, I.W.2
  • 61
    • 27844520578 scopus 로고    scopus 로고
    • Enhanced ex vivo buccal transport of propranolol: Evaluation of phospholipids as permeation enhancers
    • J. Lee, and Y.W. Choi Enhanced ex vivo buccal transport of propranolol: evaluation of phospholipids as permeation enhancers Arch. Pharm. Res. 26 2003 421 425 (Pubitemid 43073832)
    • (2003) Archives of Pharmacal Research , vol.26 , Issue.5 , pp. 421-425
    • Lee, J.1    Choi, Y.W.2
  • 64
    • 34547126907 scopus 로고    scopus 로고
    • Transbuccal delivery of 5-aza-2 -deoxycytidine: Effects of drug concentration, buffer solution, and bile salts on permeation
    • R. Mahalingam, H. Ravivarapu, S. Redkar, X. Li, and B.R. Jasti Transbuccal delivery of 5-aza-2 -deoxycytidine: effects of drug concentration, buffer solution, and bile salts on permeation AAPS PharmSciTech 13 2007 E55
    • (2007) AAPS PharmSciTech , vol.13 , pp. 55
    • Mahalingam, R.1    Ravivarapu, H.2    Redkar, S.3    Li, X.4    Jasti, B.R.5
  • 65
    • 18744398120 scopus 로고    scopus 로고
    • Effect of pH on in vitro permeation of ondansetron hydrochloride across porcine buccal mucosa
    • DOI 10.1081/PDT-200054437
    • R.C. Mashru, V.B. Sutariva, M.G. Sankalia, and J.M. Sankalia Effect of pH on in vitro permeation of ondansetron hydrochloride across porcine buccal mucosa Pharm. Dev. Technol. 10 2005 241 247 (Pubitemid 40677444)
    • (2005) Pharmaceutical Development and Technology , vol.10 , Issue.2 , pp. 241-247
    • Mashru, R.C.1    Sutariya, V.B.2    Sankalia, M.G.3    Sankalia, J.M.4
  • 66
    • 27444440815 scopus 로고    scopus 로고
    • Transbuccal delivery of lamotrigine across porcine buccal mucosa: In vitro determination of routes of buccal transport
    • R. Mashru, V. Sutariya, M. Sankalia, and J. Sankalia Transbuccal delivery of lamotrigine across porcine buccal mucosa: in vitro determination of routes of buccal transport J. Pharm. Pharm. Sci. 8 2005 54 62 (Pubitemid 41528870)
    • (2005) Journal of Pharmacy and Pharmaceutical Sciences , vol.8 , Issue.1 , pp. 54-62
    • Mashru, R.1    Sutariya, V.2    Sankalia, M.3    Sankalia, J.4
  • 68
    • 62949156030 scopus 로고    scopus 로고
    • Modulation of release rate and barrier transport of Diclofenac incorporated in hydrophilic matrices: Role of cyclodextrins and implications in oral drug delivery
    • A. Miro, A. Rondinone, A. Nappi, F. Ungaro, F. Quaglia, and M.I. La Rotonda Modulation of release rate and barrier transport of Diclofenac incorporated in hydrophilic matrices: role of cyclodextrins and implications in oral drug delivery Eur. J. Pharm. Biopharm. 72 2009 76 82
    • (2009) Eur. J. Pharm. Biopharm. , vol.72 , pp. 76-82
    • Miro, A.1    Rondinone, A.2    Nappi, A.3    Ungaro, F.4    Quaglia, F.5    La Rotonda, M.I.6
  • 70
    • 0031051750 scopus 로고    scopus 로고
    • Biomembrane permeation of nicotine: Mechanistic studies with porcine mucosae and skin
    • DOI 10.1021/js960095w
    • M.K. Nair, D.J. Chetty, H. Ho, and Y.W. Chien Biomembrane permeation of nicotine: mechanistic studies with porcine mucosae and skin J. Pharm. Sci. 86 1997 257 262 (Pubitemid 27078395)
    • (1997) Journal of Pharmaceutical Sciences , vol.86 , Issue.2 , pp. 257-262
    • Nair, M.K.1    Chetty, D.J.2    Ho, H.3    Chien, Y.W.4
  • 71
    • 0344443713 scopus 로고    scopus 로고
    • The effect of various in vitro conditions on the permeability characteristics of the buccal mucosa
    • DOI 10.1002/jps.10505
    • J.A. Nicolazzo, B.L. Reed, and B.C. Finnin The effect of various in vitro conditions on the permeability characteristics of the buccal mucosa J. Pharm. Sci. 92 2003 2399 2410 (Pubitemid 37484766)
    • (2003) Journal of Pharmaceutical Sciences , vol.92 , Issue.12 , pp. 2399-2410
    • Nicolazzo, J.A.1    Reed, B.L.2    Finnin, B.C.3
  • 72
    • 3843104844 scopus 로고    scopus 로고
    • Modification of buccal drug delivery following pretreatment with skin penetration enhancers
    • DOI 10.1002/jps.20113
    • J.A. Nicolazzo, B.L. Reed, and B.C. Finnin Modification of buccal drug delivery following pretreatment with skin penetration enhancers J. Pharm. Sci. 93 2004 2054 2063 (Pubitemid 39045486)
    • (2004) Journal of Pharmaceutical Sciences , vol.93 , Issue.8 , pp. 2054-2063
    • Nicolazzo, J.A.1    Reed, B.L.2    Finnin, B.C.3
  • 73
    • 17744383224 scopus 로고    scopus 로고
    • Enhanced buccal mucosal retention and reduced buccal permeability of estradiol in the presence of padimate O and Azone®: A mechanistic study
    • DOI 10.1002/jps.20240
    • J.A. Nicolazzo, B.L. Reed, and B.C. Finnin Enhanced buccal mucosal retention and reduced buccal permeability of estradiol in the presence of padimate O and Azone: a mechanistic study J. Pharm. Sci. 94 2005 873 882 (Pubitemid 40577319)
    • (2005) Journal of Pharmaceutical Sciences , vol.94 , Issue.4 , pp. 873-882
    • Nicolazzo, J.A.1    Reed, B.L.2    Finnin, B.C.3
  • 74
    • 0033968975 scopus 로고    scopus 로고
    • TR146 cells grown on filters as a model of human buccal epithelium: IV. Permeability of water, mannitol, testosterone and β-adrenoceptor antagonists. Comparison to human, monkey and porcine buccal mucosa
    • DOI 10.1016/S0378-5173(99)00368-3, PII S0378517399003683
    • H.M. Nielsen, and M.R. Rassing TR146 cells grown on filters as a model of human buccal epithelium: IV. Permeability of water, mannitol, testosterone and beta-adrenoceptor antagonists. Comparison to human, monkey and porcine buccal mucosa Int. J. Pharm. 194 2000 155 167 (Pubitemid 30110678)
    • (2000) International Journal of Pharmaceutics , vol.194 , Issue.2 , pp. 155-167
    • Nielsen, H.M.1    Rassing, M.R.2
  • 75
    • 0032790774 scopus 로고    scopus 로고
    • TR146 cells grown on filters as a model of human buccal epithelium: Permeability of fluorescein isothiocyanate-labelled dextrans in the presence of sodium glycocholate
    • DOI 10.1016/S0168-3659(99)00081-4, PII S0168365999000814
    • H.M. Nielsen, J.C. Verhoef, M. Ponec, and M.R. Rassing TR146 cells grown on filters as a model of human buccal epithelium: permeability of fluorescein isothiocyanate-labelled dextrans in the presence of sodium glycocholate J. Control. Release 60 1999 223 233 (Pubitemid 29335948)
    • (1999) Journal of Controlled Release , vol.60 , Issue.2-3 , pp. 223-233
    • Nielsen, H.M.1    Verhoef, J.C.2    Ponec, M.3    Rassing, M.R.4
  • 76
    • 0035997043 scopus 로고    scopus 로고
    • Nicotine permeability across the buccal TR146 cell culture model and porcine buccal mucosa in vitro: Effect of pH and concentration
    • DOI 10.1016/S0928-0987(02)00083-0, PII S0928098702000830
    • H.M. Nielsen, and M.R. Rassing Nicotine permeability across the buccal TR146 cell culture model and porcine buccal mucosa in vitro: effect of pH and concentration Eur. J. Pharm. Sci. 16 2002 151 157 (Pubitemid 34786449)
    • (2002) European Journal of Pharmaceutical Sciences , vol.16 , Issue.3 , pp. 151-157
    • Nielsen, H.M.1    Rassing, M.R.2
  • 77
    • 80055005118 scopus 로고    scopus 로고
    • Enhanced transbuccal salmon calcitonin (sCT) delivery: Effect of chemical enhancers and electrical assistance on in vitro sCT buccal permeation
    • D.H. Oh, K.H. Chun, S.O. Jeon, J.W. Kang, and S. Lee Enhanced transbuccal salmon calcitonin (sCT) delivery: effect of chemical enhancers and electrical assistance on in vitro sCT buccal permeation Eur. J. Pharm. Biopharm. 79 2011 357 363
    • (2011) Eur. J. Pharm. Biopharm. , vol.79 , pp. 357-363
    • Oh, D.H.1    Chun, K.H.2    Jeon, S.O.3    Kang, J.W.4    Lee, S.5
  • 80
    • 79958200561 scopus 로고    scopus 로고
    • Development of bioadhesive buccal tablets for felodipine and pioglitazone in combined dosage form: In vitro, ex vivo, and in vivo characterization
    • C.R. Palem, R. Gannu, S.K. Yamsani, V.V. Yamsani, and M.R. Yamsani Development of bioadhesive buccal tablets for felodipine and pioglitazone in combined dosage form: in vitro, ex vivo, and in vivo characterization Drug Deliv. 18 2011 344 352
    • (2011) Drug Deliv. , vol.18 , pp. 344-352
    • Palem, C.R.1    Gannu, R.2    Yamsani, S.K.3    Yamsani, V.V.4    Yamsani, M.R.5
  • 81
    • 82055185082 scopus 로고    scopus 로고
    • Transmucosal delivery of domperidone from bilayered buccal patches: In vitro, ex vivo and in vivo characterization
    • C.R. Palem, R. Gannu, N. Doodipala, V.V. Yamsani, and M.R. Yamsani Transmucosal delivery of domperidone from bilayered buccal patches: in vitro, ex vivo and in vivo characterization Arch. Pharm. Res. 34 2011 1701 1710
    • (2011) Arch. Pharm. Res. , vol.34 , pp. 1701-1710
    • Palem, C.R.1    Gannu, R.2    Doodipala, N.3    Yamsani, V.V.4    Yamsani, M.R.5
  • 82
    • 0022256277 scopus 로고
    • A study into the mucosal absorption of isosorbide dinitrate at different intraoral sites
    • DOI 10.1016/0030-4220(85)90006-4
    • S.J. Pimlott, and M. Addy A study into the mucosal absorption of isosorbide dinitrate at different intraoral sites Oral Surg. Oral Med. Oral Pathol. 59 1985 145 148 (Pubitemid 15046960)
    • (1985) Oral Surgery Oral Medicine and Oral Pathology , vol.59 , Issue.2 , pp. 145-148
    • Pimlott, S.J.1    Addy, M.2
  • 83
    • 84894155583 scopus 로고    scopus 로고
    • Formulation and evaluation of bucco-adhesive tablets of sumatriptan succinate
    • R.I. Prasanna, P. Anitha, and C.M. Chetty Formulation and evaluation of bucco-adhesive tablets of sumatriptan succinate Int. J. Pharm. Investig. 1 2011 182 191
    • (2011) Int. J. Pharm. Investig. , vol.1 , pp. 182-191
    • Prasanna, R.I.1    Anitha, P.2    Chetty, C.M.3
  • 85
    • 79959467189 scopus 로고    scopus 로고
    • Development and characterization of mucoadhesive patches of salbutamol sulfate for unidirectionalbuccal drug delivery
    • A. Puratchikody, V.V. Prasanth, S.T. Mathew, and B.A. Kumar Development and characterization of mucoadhesive patches of salbutamol sulfate for unidirectionalbuccal drug delivery Acta Pharm. 61 2011 157 170
    • (2011) Acta Pharm. , vol.61 , pp. 157-170
    • Puratchikody, A.1    Prasanth, V.V.2    Mathew, S.T.3    Kumar, B.A.4
  • 86
    • 84899923206 scopus 로고    scopus 로고
    • Comparative buccal permeability enhancement of didanosine and tenofovir by potential multifunctional polymeric excipients and their effects on porcine buccal histology
    • S. Rambharose, E. Ojewole, I. Mackraj, and T. Govender Comparative buccal permeability enhancement of didanosine and tenofovir by potential multifunctional polymeric excipients and their effects on porcine buccal histology Pharm. Dev. Technol. 19 2014 82 90
    • (2014) Pharm. Dev. Technol. , vol.19 , pp. 82-90
    • Rambharose, S.1    Ojewole, E.2    Mackraj, I.3    Govender, T.4
  • 87
  • 88
    • 80155188449 scopus 로고    scopus 로고
    • Particle size reduction to the nanometer range: A promising approach to improve buccal absorption of poorly water-soluble drugs
    • S. Rao, Y. Song, F. Peddie, and A.M. Evans Particle size reduction to the nanometer range: a promising approach to improve buccal absorption of poorly water-soluble drugs Int. J. Nanomedicine 6 2011 1245 1251
    • (2011) Int. J. Nanomedicine , vol.6 , pp. 1245-1251
    • Rao, S.1    Song, Y.2    Peddie, F.3    Evans, A.M.4
  • 89
    • 0026087117 scopus 로고
    • Human buccal absorption. I. A method for estimating the transfer kinetics of drugs across the human buccal membrane
    • M.J. Rathbone Human buccal absorption. I. A method for estimating the transfer kinetics of drugs across the human buccal membrane Int. J. Pharm. 69 1991 103 108
    • (1991) Int. J. Pharm. , vol.69 , pp. 103-108
    • Rathbone, M.J.1
  • 90
    • 0022374087 scopus 로고
    • Characteristics of four new human cell lines derived from squamous cell carcinomas of the head and neck
    • H.T. Rupniak, C. Rowlatt, E.B. Lane, J.G. Steele, L.K. Trejdosiewicz, B. Laskiewicz, S. Povey, and B.T. Hill Characteristics of four new human cell lines derived from squamous cell carcinomas of the head and neck J. Natl. Cancer Inst. 75 1985 621 635 (Pubitemid 16222391)
    • (1985) Journal of the National Cancer Institute , vol.75 , Issue.4 , pp. 621-635
    • Rupniak, H.T.1    Rowlatt, C.2    Lane, E.B.3
  • 91
    • 41549164865 scopus 로고    scopus 로고
    • Transbuccal delivery of chlorpheniramine maleate from mucoadhesive buccal patches
    • DOI 10.1080/10717540801952639, PII 791819432
    • K.C. Sekhar, K.V. Naidu, Y.V. Vishnu, R. Gannu, V. Kishan, and Y.M. Rao Transbuccal delivery of chlorpheniramine maleate from mucoadhesive buccal patches Drug Deliv. 15 2008 185 191 (Pubitemid 351465720)
    • (2008) Drug Delivery , vol.15 , Issue.3 , pp. 185-191
    • Sekhar, K.C.1    Naidu, K.V.S.2    Vishnu, Y.V.3    Gannu, R.4    Kishan, V.5    Rao, Y.M.6
  • 92
    • 0032509916 scopus 로고    scopus 로고
    • In vitro studies on enhancing effect of sodium glycocholate on transbuccal permeation of morphine hydrochloride
    • DOI 10.1016/S0168-3659(97)00099-0, PII S0168365997000990
    • S. Senel, D. Duchêne, A.A. Hincal, Y. Capan, and G. Ponchel In vitro studies on enhancing effect of sodium glycocholate on transbuccal permeation of morphine hydrochloride J. Control. Release 51 1998 107 113 (Pubitemid 28252861)
    • (1998) Journal of Controlled Release , vol.51 , Issue.2-3 , pp. 107-113
    • Senel, S.1    Duchene, D.2    Hincal, A.A.3    Capan, Y.4    Ponchel, G.5
  • 93
    • 0034308327 scopus 로고    scopus 로고
    • Enhancing effect of chitosan on peptide drug delivery across buccal mucosa
    • DOI 10.1016/S0142-9612(00)00134-4, PII S0142961200001344
    • S. Senel, M.J. Kremer, S. Kas, P.W. Wertz, A.A. Hincal, and C.A. Squier Enhancing effect of chitosan on peptide drug delivery across buccal mucosa Biomaterials 21 2000 2067 2071 (Pubitemid 30488077)
    • (2000) Biomaterials , vol.21 , Issue.20 , pp. 2067-2071
    • Senel, S.1    Kremer, M.J.2    Kas, S.3    Wertz, P.W.4    Hincal, A.A.5    Squier, C.A.6
  • 95
    • 0031690410 scopus 로고    scopus 로고
    • Transbuccal delivery of acyclovir: I. In vitro determination of routes of buccal transport
    • DOI 10.1023/A:1011927521627
    • A.H. Shojaei, B. Berner, and L. Xiaoling Transbuccal delivery of acyclovir: I. In vitro determination of routes of buccal transport Pharm. Res. 15 1998 1182 1188 (Pubitemid 28401707)
    • (1998) Pharmaceutical Research , vol.15 , Issue.8 , pp. 1182-1188
    • Shojaei, A.H.1    Berner, B.2    Li, X.3
  • 96
    • 0032751892 scopus 로고    scopus 로고
    • Transbuccal permeation of a nucleoside analog, dideoxycytidine: Effects of menthol as a permeation enhancer
    • DOI 10.1016/S0378-5173(99)00301-4, PII S0378517399003014
    • A.H. Shojaei, M. Khan, G. Lim, and R. Khosravan Transbuccal permeation of a nucleoside analog, dideoxycytidine: effects of menthol as a permeation enhancer Int. J. Pharm. 192 1999 139 146 (Pubitemid 29531548)
    • (1999) International Journal of Pharmaceutics , vol.192 , Issue.2 , pp. 139-146
    • Shojaei, A.H.1    Khan, M.2    Lim, G.3    Khosravan, R.4
  • 99
    • 0017256424 scopus 로고
    • The permeability of keratinized and nonkeratinized oral epithelium to lanthanum in vivo
    • C.A. Squier, and L. Rooney The permeability of keratinized and nonkeratinized oral epithelium to lanthanum in vivo J. Ultrastruct. Res. 54 1976 286 295
    • (1976) J. Ultrastruct. Res. , vol.54 , pp. 286-295
    • Squier, C.A.1    Rooney, L.2
  • 100
    • 0021779325 scopus 로고
    • In-vitro permeability of porcine oral mucosa after epithelial separation, stripping and hydration
    • C.A. Squier, and B.K. Hall In-vitro permeability of porcine oral mucosa after epithelial separation, stripping and hydration Arch. Oral Biol. 30 1985 485 491
    • (1985) Arch. Oral Biol. , vol.30 , pp. 485-491
    • Squier, C.A.1    Hall, B.K.2
  • 101
  • 103
    • 0003070827 scopus 로고    scopus 로고
    • Structure and function of the oral mucosa and implications for drug delivery
    • M.J. Rathbone, Marcel Dekker Inc. New York
    • C.A. Squier, and P.W. Wertz Structure and function of the oral mucosa and implications for drug delivery M.J. Rathbone, Oral Mucosal Drug Delivery 1996 Marcel Dekker Inc. New York 1 26
    • (1996) Oral Mucosal Drug Delivery , pp. 1-26
    • Squier, C.A.1    Wertz, P.W.2
  • 106
    • 0023717306 scopus 로고
    • A method to study the kinetics of oral mucosal drug absorption from solutions
    • I.G. Tucker A method to study the kinetics of oral mucosal drug absorption from solutions J. Pharm. Pharmacol. 40 1988 679 683
    • (1988) J. Pharm. Pharmacol. , vol.40 , pp. 679-683
    • Tucker, I.G.1
  • 107
    • 0034090783 scopus 로고    scopus 로고
    • Permeation of sumatriptan through human vaginal and buccal mucosa
    • DOI 10.1046/j.1526-4610.2000.00019.x
    • P. van der Bijl, L. Penkler, and A.D. van Eyk Permeation of sumatriptan through human vaginal and buccal mucosa Headache 40 2000 137 141 (Pubitemid 30132054)
    • (2000) Headache , vol.40 , Issue.2 , pp. 137-141
    • Van Der Bijl, P.1    Penkler, L.2    Van Eyk, A.D.3
  • 109
    • 33947113036 scopus 로고    scopus 로고
    • Evaluation of HO-1-u-1 cell line as an in vitro model for sublingual drug delivery involving passive diffusion-Initial validation studies
    • DOI 10.1016/j.ijpharm.2006.10.012, PII S0378517306008507
    • Y. Wang, Z. Zuo, K.K. Lee, and M.S. Chow Evaluation of HO-1-u-1 cell line as an in vitro model for sublingual drug delivery involving passive diffusion - initial validation studies Int. J. Pharm. 334 2007 27 34 (Pubitemid 46400308)
    • (2007) International Journal of Pharmaceutics , vol.334 , Issue.1-2 , pp. 27-34
    • Wang, Y.1    Zuo, Z.2    Lee, K.K.H.3    Chow, M.S.S.4
  • 110
    • 61449178732 scopus 로고    scopus 로고
    • HO-1-u-1 model for screening sublingual drug delivery - Influence of pH, osmolarity and permeation enhancer
    • Y. Wang, Z. Zuo, and M.S. Chow HO-1-u-1 model for screening sublingual drug delivery - influence of pH, osmolarity and permeation enhancer Int. J. Pharm. 370 2009 68 74
    • (2009) Int. J. Pharm. , vol.370 , pp. 68-74
    • Wang, Y.1    Zuo, Z.2    Chow, M.S.3
  • 112
    • 81455136017 scopus 로고    scopus 로고
    • Transbuccal delivery of CNS therapeutic nanoparticles: Synthesis, characterization, and in vitro permeation studies
    • Q. Yuan, Y. Fu, W.J. Kao, D. Janigro, and H. Yang Transbuccal delivery of CNS therapeutic nanoparticles: synthesis, characterization, and in vitro permeation studies ACS Chem. Neurosci. 2 2011 676 683
    • (2011) ACS Chem. Neurosci. , vol.2 , pp. 676-683
    • Yuan, Q.1    Fu, Y.2    Kao, W.J.3    Janigro, D.4    Yang, H.5
  • 113
    • 0001794494 scopus 로고    scopus 로고
    • Routes of drug transport across oral mucosa
    • M.J. Rathbone, Marcel Dekker Inc. New York
    • H. Zhang, and J.R. Robinson Routes of drug transport across oral mucosa M.J. Rathbone, Oral Mucosal Drug Delivery 1996 Marcel Dekker Inc. New York 51 63
    • (1996) Oral Mucosal Drug Delivery , pp. 51-63
    • Zhang, H.1    Robinson, J.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.