Construction and in vitro characterization of an optimized porosity-enabled amalgamated matrix for sustained transbuccal drug delivery

International Journal of Pharmaceutics

Volumn 391, Issue 1-2, 2010, Pages 79-89

  Adeleke, Oluwatoyin A ^a   Pillay, Viness ^a   du Toit, Lisa C ^a   Choonara, Yahya E ^a  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

Author keywords

Experimental design; Mechanistic characterization; Porosity enabled amalgamated matrix; Simultaneous optimization; Transbuccal drug delivery

Indexed keywords

ADHESIVE AGENT; POROSITY ENABLED AMALGAMATED MATRIX; UNCLASSIFIED DRUG;

ADHESION; ANIMAL TISSUE; ARTICLE; CHEEK MUCOSA; CONTROLLED STUDY; DRUG ADMINISTRATION ROUTE; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG PENETRATION; DRUG RELEASE; EX VIVO STUDY; EXPERIMENTAL DESIGN; FORCE; FREEZE DRYING; IN VITRO STUDY; INDEPENDENT VARIABLE; MOLECULAR WEIGHT; NONHUMAN; POROSITY; PRIORITY JOURNAL; STATISTICAL ANALYSIS; STRENGTH; TRANSMUCOSAL DRUG ADMINISTRATION;

ADHESIVES; ADMINISTRATION, BUCCAL; ANIMALS; CHEMISTRY, PHARMACEUTICAL; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; MOUTH MUCOSA; PERMEABILITY; PHASE TRANSITION; PHENYTOIN; POROSITY; RHEOLOGY; SURFACE PROPERTIES; SWINE;

EID: 77952888510     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.02.023     Document Type: Article

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