Statistical optimization of insulin-loaded Pluronic F-127 gels for buccal delivery of basal insulin

Pharmaceutical Development and Technology

Volumn 17, Issue 3, 2012, Pages 363-374

  Das, Nilanjana ^a   Madan, Parshotam ^a   Lin, Senshang ^a  

^a ST JOHN'S UNIVERSITY   (United States)

Author keywords

Basal insulin; Buccal; Pluronic F 127; Statistical optimization

Indexed keywords

GLYCOCHOLATE SODIUM; HYDROXYPROPYLMETHYLCELLULOSE; INSULIN; POLOXAMER; SODIUM SULFATE;

ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG PENETRATION; FACTORIAL DESIGN; GELATION; IN VITRO STUDY; INSULIN RELEASE; MALE; NONHUMAN; PRIORITY JOURNAL; PROCESS OPTIMIZATION; REGRESSION ANALYSIS; STATISTICAL CONCEPTS; STATISTICAL OPTIMIZATION;

ADHESIVENESS; ADMINISTRATION, BUCCAL; ANIMALS; BLOOD GLUCOSE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; EXCIPIENTS; FEASIBILITY STUDIES; GELS; GLYCOCHOLIC ACID; HYPOGLYCEMIC AGENTS; INSULIN; MALE; METHYLCELLULOSE; MOUTH MUCOSA; POLOXAMER; RATS; RATS, SPRAGUE-DAWLEY; REGRESSION ANALYSIS; SULFATES; SWINE; TIME FACTORS;

EID: 84859977179     PISSN: 10837450     EISSN: 10979867     Source Type: Journal    
DOI: 10.3109/10837450.2010.542164     Document Type: Article

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