Modulation of release rate and barrier transport of Diclofenac incorporated in hydrophilic matrices: Role of cyclodextrins and implications in oral drug delivery

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 72, Issue 1, 2009, Pages 76-82

  Miro, Agnese ^a   Rondinone, Autilia ^a   Nappi, Antonella ^a   Ungaro, Francesca ^a   Quaglia, Fabiana ^a   La Rotonda, Maria Immacolata ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Barrier transport; Cyclodextrins; Diclofenac; Hydrophilic matrices; Release rate

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; DICLOFENAC; MACROGOL; POLYOX WSR 205; POLYOX WSR 301; SILICON; UNCLASSIFIED DRUG;

ANIMAL TISSUE; AQUEOUS SOLUTION; ARTICLE; ARTIFICIAL MEMBRANE; CHEEK MUCOSA; COMPLEX FORMATION; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG SOLUBILITY; DRUG TRANSPORT; HYDROGEL; HYDROPHILICITY; IONIZATION; NONHUMAN; PH; SWINE; TABLET FORMULATION; TABLET MATRIX;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL TRANSPORT; CHEMISTRY, PHARMACEUTICAL; CYCLODEXTRINS; DICLOFENAC; DRUG DELIVERY SYSTEMS; HYDROGEN-ION CONCENTRATION; KINETICS; MOUTH MUCOSA; PERMEABILITY; POLYETHYLENE GLYCOLS; SALTS; SOLUBILITY; SWINE; TABLETS;

EID: 62949156030     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2008.12.006     Document Type: Article

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