Effect of drug lipophilicity and ionization on permeability across the buccal mucosa: A technical note

AAPS PharmSciTech

Volumn 9, Issue 2, 2008, Pages 501-504

  Kokate, Amit ^a   Li, Xiaoling ^a   Jasti, Bhaskara ^a  

^a UNIVERSITY OF THE PACIFIC   (United States)

Author keywords

Buccal; Distribution coefficient (logD); Ionization; Partition coefficient (logP); Permeability

Indexed keywords

AMITRIPTYLINE; CAFFEINE; DILTIAZEM; LIDOCAINE; METOPROLOL; NAPROXEN; NIMESULIDE; PHENAZONE; PINDOLOL; PROPRANOLOL; VERAPAMIL; WARFARIN; DRUG;

ANIMAL TISSUE; ARTICLE; CHEEK MUCOSA; CHROMATOGRAPHY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG PENETRATION; IN VITRO STUDY; IONIZATION; LIPOPHILICITY; MEMBRANE PERMEABILITY; NONHUMAN; ANIMAL; BIOLOGICAL MODEL; BUCCAL DRUG ADMINISTRATION; CHEMISTRY; METABOLISM; METHODOLOGY; MOUTH MUCOSA; PERMEABILITY; PHARMACEUTICS; SOLUBILITY; SWINE;

ADMINISTRATION, BUCCAL; ANIMALS; MODELS, BIOLOGICAL; MOUTH MUCOSA; PERMEABILITY; PHARMACEUTICAL PREPARATIONS; SOLUBILITY; SWINE; TECHNOLOGY, PHARMACEUTICAL;

EID: 51449091366     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-008-9071-7     Document Type: Article

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