Enhanced transbuccal salmon calcitonin (sCT) delivery: Effect of chemical enhancers and electrical assistance on in vitro sCT buccal permeation

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 79, Issue 2, 2011, Pages 357-363

  Oh, Dong Ho ^a   Chun, Kyeung Hwa ^a   Jeon, Sang Ok ^a   Kang, Jeong Won ^b   Lee, Sangkil ^a  

^a Inje University   (South Korea)

^b Chungju National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ALCOHOL; EOSIN; GLYCODEOXYCHOLIC ACID; HEMATOXYLIN; LIPID; SALCATONIN;

ANIMAL TISSUE; ARTICLE; BUCCAL DRUG ADMINISTRATION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG PENETRATION; ELECTRIC CONDUCTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HISTOLOGY; IN VITRO STUDY; INFRARED SPECTROSCOPY; IONTOPHORESIS; NONHUMAN; STATISTICAL SIGNIFICANCE; SWINE;

EID: 80055005118     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2011.05.010     Document Type: Article

References (43)

1. F. Veuillez, Y.N. Kalia, Y. Jacques, J. Deshusses, P. Buri, Factors and strategies for improving buccal absorption of peptides, Eur. J. Pharm. Biopharm. 51 (2001) 93-109. (Pubitemid 32162488)
2. F.J. Gomez-Perez, J.A. Rull, Insulin therapy: current alternatives, Arch. Med. Res. 36 (2005) 258-272. (Pubitemid 40755139)
3. A.E. Pontiroli, Peptide hormones: review of current and emerging uses by nasal delivery, Adv. Drug Deliv. Rev. 29 (1998) 81-87. (Pubitemid 28044087)
4. S. Yu, Y. Zhao, F. Wu, X. Zhang, W. Lu, H. Zhang, Q. Zhang, Nasal insulin delivery in the chitosan solution: in vitro and in vivo studies, Int. J. Pharm. 281 (2004) 11-23. (Pubitemid 39024259)
5. A. Yamamoto, S. Muranishi, Rectal drug delivery systems improvement of rectal peptide absorption by absorption enhancers, protease inhibitors and chemical modification, Adv. Drug Deliv. Rev. 28 (1997) 275-299. (Pubitemid 28078671)
6. F.W. Merkus, J.C. Verhoef, N.G. Schipper, E. Marttin, Nasal mucociliary clearance as a factor in nasal drug delivery, Adv. Drug Deliv. Rev. 29 (1998) 13-38. (Pubitemid 28045041)
7. A. Chaturvedula, D.P. Joshi, C. Anderson, R.L. Morris, W.L. Sembrowich, A.K. Banga, In vivo iontophoretic delivery and pharmacokinetics of salmon calcitonin, Int. J. Pharm. 297 (2005) 190-196. (Pubitemid 40720279)
8. G. Golomb, A. Avramoff, A. Hoffman, A new route of drug administration: intrauterine delivery of insulin and calcitonin, Pharm. Res. 10 (1993) 828-833. (Pubitemid 23167563)
9. M. Mackay, J. Phillips, J. Hastewell, Peptide drug delivery: colonic and rectal absorption, Adv. Drug Deliv. Rev. 28 (1997) 253-257.
10. A. Leone-Bay, D.R. Paton, J.J. Weidner, The development of delivery agents that facilitate the oral absorption of macromolecular drugs, Med. Res. Rev. 20 (2000) 169-186. (Pubitemid 30134324)
11. A.J. Hoogstraate, P.W. Wertz, Drug delivery via the buccal mucosa, Pharm. Sci. Technol. Today 1 (1998) 309-316. (Pubitemid 28467747)
12. A.J. Hoogstraate, P.W. Wertz, C.A. Squier, A.B. Geest, W. Abraham, M.D. Garrison, J.C. Verhoef, H.E. Junginger, H.E. Boddé, Effects of the penetration enhancer glycodeoxycholate on the lipid integrity in porcine buccal epithelium in vitro, Eur. J. Pharm. Sci. 5 (1997) 189-198. (Pubitemid 27273942)
13. O. Pillai, R. Panchagnula, Transdermal iontophoresis of insulin. V. Effect of terpenes, J. Control. Release 88 (2003) 287-296. (Pubitemid 36287345)
14. K.S. Bhatia, J. Singh, Effect of linolenic acid/ethanol or limonene/ethanol and iontophoresis on the in vitro percutaneous absorption of LHRH and ultrastructure of human epidermis, Int. J. Pharm. 180 (1999) 235-250. (Pubitemid 29238207)
15. L.I. Giannola, V. De Caro, G. Giandalia, M.G. Siragusa, G. Campisi, A.M. Florena, T. Ciach, Diffusion of naltrexone across reconstituted human oral epithelium and histomorphological features, Eur. J. Pharm. Biopharm. 65 (2007) 238-246. (Pubitemid 46038078)
16. J. Jacobsen, Buccal iontophoretic delivery of atenolol HCl employing a new in vitro three-chamber permeation cell, J. Control. Release 70 (2001) 83-95. (Pubitemid 32144795)
17. L.I. Giannola, V. De Caro, G. Giandalia, M.G. Siragusa, C. Tripodo, A.M. Florena, G. Campisi, Release of naltrexone on buccal mucosa: permeation studies, histological aspects and matrix system design, Eur. J. Pharm. Biopharm. 67 (2007) 425-433. (Pubitemid 47211903)
18. S.L. Chang, G.A. Hofmann, L. Zhang, L.J. Deftos, A.K. Banga, Transdermal iontophoretic delivery of salmon calcitonin, Int. J. Pharm. 200 (2000) 107-113. (Pubitemid 30177255)
19. Y. Hee Lee, G.D. Leesman, V. Makhey, H. Yu, P. Hu, B. Perry, J.P. Sutyak, E.J. Wagner, L.M. Falzone, W. Stern, P.J. Sinko, Regional oral absorption, hepatic first-pass effect, and non-linear disposition of salmon calcitonin in beagle dogs, Eur. J. Pharm. Biopharm. 50 (2000) 205-211.
20. I. Diaz del Consuelo, F. Falson, R.H. Guy, Y. Jacques, Ex vivo evaluation of bioadhesive films for buccal delivery of fentanyl, J. Control. Release 122 (2007) 135-140. (Pubitemid 47361402)
21. K.C. Lee, Y.J. Lee, H.M. Song, C.J. Chun, P.P. DeLuca, Degradation of synthetic salmon calcitonin in aqueous solution, Pharm. Res. 9 (1992) 1521-1523.
22. Y.N. Kalia, A. Naik, J. Garrison, R.H. Guy, Iontophoretic drug delivery, Adv. Drug Deliv. Rev. 56 (2004) 619-658. (Pubitemid 38326937)
23. K.B. Sloan, H.D. Beall, H.E. Taylor, J.J. Getz, R. Villaneuva, R. Nipper, K. Smith, Transdermal delivery of theophylline from alcohol vehicles, Int. J. Pharm. 171 (1998) 185-193. (Pubitemid 29023111)
24. J.A. Nicolazzo, B.L. Reed, B.C. Finnin, Buccal penetration enhancers - how do they really work?, J Control. Release 105 (2005) 1-15. (Pubitemid 40805471)
25. T. Matsuyama, T. Morita, Y. Horikiri, H. Yamahara, H. Yoshino, Enhancement of nasal absorption of large molecular weight compounds by combination of mucolytic agent and nonionic surfactant, J. Control. Release 110 (2006) 347-352. (Pubitemid 41827488)
26. A.J. Hoogstraate, C. Cullander, S. Senel, J.C. Verhoef, H.E. Junginger, H.E. Boddé, Effects of bile salts on transport rates and routes of FITC-labelled compounds across porcine buccal epithelium in vitro, J. Control. Release 40 (1996) 211-221. (Pubitemid 26238373)
27. A.K. Nugroho, L. Li, D. Dijkstra, H. Wikstrom, M. Danhof, J.A. Bouwstra, Transdermal iontophoresis of the dopamine agonist 5-OH-DPAT in human skin in vitro, J. Control. Release 103 (2005) 393-403. (Pubitemid 40342537)
28. M. Kottgen, A.E. Busch, M.J. Hug, R. Greger, K. Kunzelmann, N-Acetyl-L-cysteine and its derivatives activate a Cl-conductance in epithelial cells, Pflugers Arch. 431 (1996) 549-555. (Pubitemid 26091699)
29. B.W. Barry, Novel mechanisms and devices to enable successful transdermal drug delivery, Eur. J. Pharm. Sci. 14 (2001) 101-114. (Pubitemid 32737532)
30. Y.B. Schuetz, A. Naik, R.H. Guy, Y.N. Kalia, Effect of amino acid sequence on transdermal iontophoretic peptide delivery, Eur. J. Pharm. Sci. 26 (2005) 429-437. (Pubitemid 41551576)
31. N.K. Swarnakar, V. Jain, V. Dubey, D. Mishra, N.K. Jain, Enhanced oromucosal delivery of progesterone via hexosomes, Pharm. Res. 24 (2007) 2223-2230. (Pubitemid 350060713)
32. R. Panchagnula, P.S. Salve, N.S. Thomas, A.K. Jain, P. Ramarao, Transdermal delivery of naloxone: effect of water, propylene glycol, ethanol and their binary combinations on permeation through rat skin, Int. J. Pharm. 219 (2001) 95-105. (Pubitemid 32391369)
33. G.M. Golden, D.B. Guzek, R.R. Harris, J.E. McKie, R.O. Potts, Lipid thermotropic transitions in human stratum corneum, J. Invest. Dermatol. 86 (1986) 255-259. (Pubitemid 16124158)
34. R.O. Potts, M.L. Francoeur, Infrared spectroscopy of stratum corneum lipids: in vitro results and their relevance to permeability, in: K.A. Walters, J. Hadgraft (Eds.), Pharmaceutical Skin Permeation Enhancement, vol. 59, Marcel Dekker, New York, 1993, pp. 269-291.
35. K. Takahashi, H. Sakano, M. Yoshida, N. Numata, N. Mizuno, Characterization of the influence of polyol fatty acid esters on the permeation of diclofenac through rat skin, J. Control. Release 73 (2001) 351-358. (Pubitemid 32539262)
36. H.K. Vaddi, P.C. Ho, S.Y. Chan, Terpenes in propylene glycol as skin-penetration enhancers: permeation and partition of haloperidol, Fourier transform infrared spectroscopy, and differential scanning calorimetry, J. Pharm. Sci. 91 (2002) 1639-1651. (Pubitemid 34680226)
37. K. Knutson, S.L. Krill, W.J. Lambert, W.I. Higuchi, Physicochemical aspects of transdermal permeation, J. Control. Release 6 (1987) 59-74. (Pubitemid 18017722)
38. A. Naik, R.H. Guy, Infrared spectroscopic and differential scanning calorimetric investigations of the stratum corneum barrier function, in: R.O. Potts, R.H. Guy (Eds.), Mechanisms of Transdermal Drug Delivery, vol. 83, Marcel Dekker, New York, 1997, pp. 87-162.
39. K.S. Bhatia, S. Gao, J. Singh, Effect of penetration enhancers and iontophoresis on the FT-IR spectroscopy and LHRH permeability through porcine skin, J. Control. Release 47 (1997) 81-89. (Pubitemid 27154403)
40. K. Zhao, J. Singh, Mechanisms of percutaneous absorption of tamoxifen by terpenes: eugenol, D-limonene and menthone, J. Control. Release 55 (1998) 253-260. (Pubitemid 28477616)
41. F. Veuillez, F.F. Rieg, R.H. Guy, J. Deshusses, P. Buri, Permeation of a myristoylated dipeptide across the buccal mucosa: topological distribution and evaluation of tissue integrity, Int. J. Pharm. 231 (2002) 1-9. (Pubitemid 33086813)
42. C.A. Squier, B.K. Hall, The permeability of skin and oral mucosa to water and horseradish peroxidase as related to the thickness of the permeability barrier, J. Invest. Dermatol. 84 (1985) 176-179. (Pubitemid 15127885)
43. C.A. Squier, L. Rooney, The permeability of keratinized and nonkeratinized oral epithelium to lanthanum in vivo, J. Ultrastruct. Res. 54 (1976) 286-295.