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Volumn 65, Issue 3, 2014, Pages 327-339

Immunomodulatoryand potential therapeutic role of mesenchymal stem cells in periodontitis

Author keywords

BMP 2; Dental; Gene therapy; Immunomodulation; Immunosuppression; Mesenchymal stem cells; Osteoprotegerin; Periodontal; Periodontitis; Regeneration; Regulatory T cells

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; COLONY STIMULATING FACTOR 1; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDOLEAMINE 2, 3 DIOXYGENASE; INTERFERON; INTERLEUKIN 23; INTERLEUKIN 6; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; PROSTAGLANDIN E2; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84902439775     PISSN: 08675910     EISSN: 18991505     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (70)

References (193)
  • 1
    • 84873708523 scopus 로고    scopus 로고
    • The oral microbiome in health and disease
    • Wade WG. The oral microbiome in health and disease. Pharmacol Res 2013; 69: 137-143.
    • (2013) Pharmacol Res , vol.69 , pp. 137-143
    • Wade, W.G.1
  • 3
    • 0035983426 scopus 로고    scopus 로고
    • Roles of salivary proteins in the adherence of oral streptococci to various orthodontic brackets
    • Ahn SJ, Kho HS, Lee SW, Nahm DS. Roles of salivary proteins in the adherence of oral streptococci to various orthodontic brackets. J Dent Res 2002; 81: 411-415.
    • (2002) J Dent Res , vol.81 , pp. 411-415
    • Ahn, S.J.1    Kho, H.S.2    Lee, S.W.3    Nahm, D.S.4
  • 6
    • 79955788939 scopus 로고    scopus 로고
    • Clinical and biochemical efficacy of minocycline in nonsurgical periodontal therapy: A randomized controlled pilot study
    • Basegmez C, Berber L, Yalcin F. Clinical and biochemical efficacy of minocycline in nonsurgical periodontal therapy: a randomized controlled pilot study. J Clin Pharmacol 2011; 51: 915-922.
    • (2011) J Clin Pharmacol , vol.51 , pp. 915-922
    • Basegmez, C.1    Berber, L.2    Yalcin, F.3
  • 7
    • 79952110794 scopus 로고    scopus 로고
    • A new specific and useful tool in differential diagnosis of periodontitis
    • Stawinska N, Kochanowska I, Zietek M. A new specific and useful tool in differential diagnosis of periodontitis. J Physiol Pharmacol 2009; 60 (Suppl. 8): 73-75.
    • (2009) J Physiol Pharmacol , vol.60 , Issue.SUPPL. 8 , pp. 73-75
    • Stawinska, N.1    Kochanowska, I.2    Zietek, M.3
  • 8
    • 79951923001 scopus 로고    scopus 로고
    • Working Group 1 of Seventh European Workshop on Periodontology. Periodontal infections: Understanding the complexity - consensus of the Seventh European Workshop on Periodontology
    • Sanz M, van Winkelhoff AJ, Working Group 1 of Seventh European Workshop on Periodontology. Periodontal infections: understanding the complexity - consensus of the Seventh European Workshop on Periodontology. J Clin Periodontol 2011; 38 (Suppl. 11): 3-6.
    • (2011) J Clin Periodontol , vol.38 , Issue.SUPPL. 11 , pp. 3-6
    • Sanz, M.1    van Winkelhoff, A.J.2
  • 10
    • 25844465700 scopus 로고    scopus 로고
    • Identification of genetic risk factors for periodontitis and possible mechanisms of action
    • Loos BG, John RP, Laine ML. Identification of genetic risk factors for periodontitis and possible mechanisms of action. J Clin Periodontol 2005; 32 (Suppl. 6): 159-179.
    • (2005) J Clin Periodontol , vol.32 , Issue.SUPPL. 6 , pp. 159-179
    • Loos, B.G.1    John, R.P.2    Laine, M.L.3
  • 11
    • 79954629555 scopus 로고    scopus 로고
    • Tooth loss in compliant and non-compliant periodontally treated patients: 7 years after active periodontal therapy
    • Ng MC, Ong MM, Lim LP, Koh CG, Chan YH. Tooth loss in compliant and non-compliant periodontally treated patients: 7 years after active periodontal therapy. J Clin Periodontol 2011; 38: 499-508.
    • (2011) J Clin Periodontol , vol.38 , pp. 499-508
    • Ng, M.C.1    Ong, M.M.2    Lim, L.P.3    Koh, C.G.4    Chan, Y.H.5
  • 12
    • 79952786345 scopus 로고    scopus 로고
    • Periodontal regeneration: A challenge for the tissue engineer?
    • Hughes FJ, Ghuman M, Talal A. Periodontal regeneration: a challenge for the tissue engineer? Proc Inst Mech Eng H 2010; 224: 1345-1358.
    • (2010) Proc Inst Mech Eng H , vol.224 , pp. 1345-1358
    • Hughes, F.J.1    Ghuman, M.2    Talal, A.3
  • 13
    • 69149092119 scopus 로고    scopus 로고
    • Does periodontal tissue regeneration really work?
    • Bosshardt DD, Sculean A. Does periodontal tissue regeneration really work? Periodontology 2000 2009; 51: 208-219.
    • (2009) Periodontology , vol.2000 , Issue.51 , pp. 208-219
    • Bosshardt, D.D.1    Sculean, A.2
  • 14
    • 77955854661 scopus 로고    scopus 로고
    • Antiinflammatory effect of BPC 157 on experimental periodontitis in rats
    • Keremi B, Lohinai Z, Komora P, et al. Antiinflammatory effect of BPC 157 on experimental periodontitis in rats. J Physiol Pharmacol 2009; 60 (Suppl. 7): 115-122.
    • (2009) J Physiol Pharmacol , vol.60 , Issue.SUPPL. 7 , pp. 115-122
    • Keremi, B.1    Lohinai, Z.2    Komora, P.3
  • 15
    • 84863530790 scopus 로고    scopus 로고
    • Anti-inflammatory effect of the endocannabinoid anandamide in experimental periodontitis and stress in the rat
    • Rettori E, De Laurentiis A, Zorrilla Zubilete M, Rettori V, Elverdin JC. Anti-inflammatory effect of the endocannabinoid anandamide in experimental periodontitis and stress in the rat. Neuroimmunomodulation 2012; 19: 293-303.
    • (2012) Neuroimmunomodulation , vol.19 , pp. 293-303
    • Rettori, E.1    de Laurentiis, A.2    Zorrilla Zubilete, M.3    Rettori, V.4    Elverdin, J.C.5
  • 16
    • 84897009273 scopus 로고    scopus 로고
    • Molecular mechanisms of mesenchymal stem cell differentiation towards osteoblasts
    • Fakhry M, Hamade E, Badran B, Buchet R, Magne D. Molecular mechanisms of mesenchymal stem cell differentiation towards osteoblasts. World J Stem Cells 2013; 5: 136-148.
    • (2013) World J Stem Cells , vol.5 , pp. 136-148
    • Fakhry, M.1    Hamade, E.2    Badran, B.3    Buchet, R.4    Magne, D.5
  • 17
    • 33747067733 scopus 로고    scopus 로고
    • Behavior of transplanted bone marrow-derived mesenchymal stem cells in periodontal defects
    • Hasegawa N, Kawaguchi H, Hirachi A, et al. Behavior of transplanted bone marrow-derived mesenchymal stem cells in periodontal defects. J Periodontol 2006; 77: 1003-1007.
    • (2006) J Periodontol , vol.77 , pp. 1003-1007
    • Hasegawa, N.1    Kawaguchi, H.2    Hirachi, A.3
  • 18
    • 84890117214 scopus 로고    scopus 로고
    • Immunomodulatory properties of dental tissue-derived mesenchymal stem cells
    • Li Z, Jiang CM, An S, et al. Immunomodulatory properties of dental tissue-derived mesenchymal stem cells. Oral Dis 2014; 20: 25-34.
    • (2014) Oral Dis , vol.20 , pp. 25-34
    • Li, Z.1    Jiang, C.M.2    An, S.3
  • 19
    • 84867705827 scopus 로고    scopus 로고
    • Interplay between mesenchymal stem cells and lymphocytes: Implications for immunotherapy and tissue regeneration
    • Wang L, Zhao Y, Shi S. Interplay between mesenchymal stem cells and lymphocytes: implications for immunotherapy and tissue regeneration. J Dent Res 2012; 91: 1003-1010.
    • (2012) J Dent Res , vol.91 , pp. 1003-1010
    • Wang, L.1    Zhao, Y.2    Shi, S.3
  • 20
    • 26644432484 scopus 로고    scopus 로고
    • Multipotent mesenchymal stem cells with immunosuppressive activity can be easily isolated from dental pulp
    • Pierdomenico L, Bonsi L, Calvitti M, et al. Multipotent mesenchymal stem cells with immunosuppressive activity can be easily isolated from dental pulp. Transplantation 2005; 80: 836-842.
    • (2005) Transplantation , vol.80 , pp. 836-842
    • Pierdomenico, L.1    Bonsi, L.2    Calvitti, M.3
  • 21
    • 34247510088 scopus 로고    scopus 로고
    • Isolation and characterization of postnatal stem cells from human dental tissues
    • Jo YY, Lee HJ, Kook S Y, et al. Isolation and characterization of postnatal stem cells from human dental tissues. Tissue Eng 2007; 13: 767-773.
    • (2007) Tissue Eng , vol.13 , pp. 767-773
    • Jo, Y.Y.1    Lee, H.J.2    Kook, S.Y.3
  • 22
    • 84891721700 scopus 로고    scopus 로고
    • Mitoxantrone ability to induce premature senescence in human dental pulp stem cells and human dermal fibroblasts
    • Seifrtova M, Havelek R, Soukup T, Filipova A, Mokry J, Rezacova M. Mitoxantrone ability to induce premature senescence in human dental pulp stem cells and human dermal fibroblasts. J Physiol Pharmacol 2013; 64: 255-266.
    • (2013) J Physiol Pharmacol , vol.64 , pp. 255-266
    • Seifrtova, M.1    Havelek, R.2    Soukup, T.3    Filipova, A.4    Mokry, J.5    Rezacova, M.6
  • 23
    • 77953192729 scopus 로고    scopus 로고
    • Mechanisms and control of pathologic bone loss in periodontitis
    • Bartold PM, Cantley MD, Haynes DR. Mechanisms and control of pathologic bone loss in periodontitis. Periodontology 2000 2010; 53: 55-69.
    • (2010) Periodontology , vol.2000 , Issue.53 , pp. 55-69
    • Bartold, P.M.1    Cantley, M.D.2    Haynes, D.R.3
  • 24
    • 84875387728 scopus 로고    scopus 로고
    • Bone morphogenetic proteins: Periodontal regeneration
    • Rao SM, Ugale GM, Warad SB. Bone morphogenetic proteins: periodontal regeneration. N Am J Med Sci 2013; 5: 161-168.
    • (2013) N Am J Med Sci , vol.5 , pp. 161-168
    • Rao, S.M.1    Ugale, G.M.2    Warad, S.B.3
  • 25
    • 77957266092 scopus 로고    scopus 로고
    • Effect of bone block graft with rhBMP-2 on vertical bone augmentation
    • Kim SJ, Shin HS, Shin SW. Effect of bone block graft with rhBMP-2 on vertical bone augmentation. Int J Oral Maxillofac Surg 2010; 39: 883-888.
    • (2010) Int J Oral Maxillofac Surg , vol.39 , pp. 883-888
    • Kim, S.J.1    Shin, H.S.2    Shin, S.W.3
  • 26
    • 67649958511 scopus 로고    scopus 로고
    • Influence of residual bone on recombinant human bone morphogenetic protein-2-induced periodontal regeneration in experimental periodontitis in dogs
    • Saito A, Saito E, Handa R, Honma Y, Kawanami M. Influence of residual bone on recombinant human bone morphogenetic protein-2-induced periodontal regeneration in experimental periodontitis in dogs. J Periodontol 2009; 80: 961-968.
    • (2009) J Periodontol , vol.80 , pp. 961-968
    • Saito, A.1    Saito, E.2    Handa, R.3    Honma, Y.4    Kawanami, M.5
  • 27
    • 84902462911 scopus 로고    scopus 로고
    • Effects of enamel matrix derivative and basic fibroblast growth factor with mu-tricalcium phosphate on periodontal regeneration in one-wall intrabony defects: An experimental study in dogs
    • Shirakata Y, Takeuchi N, Yoshimoto T, Taniyama K, Noguchi K. Effects of enamel matrix derivative and basic fibroblast growth factor with mu-tricalcium phosphate on periodontal regeneration in one-wall intrabony defects: an experimental study in dogs. Int J Periodontics Restorative Dent 2013; 33: 641-649.
    • (2013) Int J Periodontics Restorative Dent , vol.33 , pp. 641-649
    • Shirakata, Y.1    Takeuchi, N.2    Yoshimoto, T.3    Taniyama, K.4    Noguchi, K.5
  • 28
    • 34547481944 scopus 로고    scopus 로고
    • RANKL inhibition through osteoprotegerin blocks bone loss in experimental periodontitis
    • Jin Q, Cirelli JA, Park CH, et al. RANKL inhibition through osteoprotegerin blocks bone loss in experimental periodontitis. J Periodontol 2007; 78: 1300-1308.
    • (2007) J Periodontol , vol.78 , pp. 1300-1308
    • Jin, Q.1    Cirelli, J.A.2    Park, C.H.3
  • 29
    • 78650083063 scopus 로고    scopus 로고
    • Destructive and protective roles of cytokines in periodontitis: A re-appraisal from host defense and tissue destruction viewpoints
    • Garlet G P. Destructive and protective roles of cytokines in periodontitis: a re-appraisal from host defense and tissue destruction viewpoints. J Dent Res 2010; 89: 1349-1363.
    • (2010) J Dent Res , vol.89 , pp. 1349-1363
    • Garlet, G.P.1
  • 31
    • 0032540319 scopus 로고    scopus 로고
    • Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation
    • Lacey DL, Timms E, Tan HL, et al. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 1998; 93: 165-176.
    • (1998) Cell , vol.93 , pp. 165-176
    • Lacey, D.L.1    Timms, E.2    Tan, H.L.3
  • 32
    • 0031765480 scopus 로고    scopus 로고
    • A combination of osteoclast differentiation factor and macrophage-colony stimulating factor is sufficient for both human and mouse osteoclast formation in vitro
    • Quinn JM, Elliott J, Gillespie MT, Martin TJ. A combination of osteoclast differentiation factor and macrophage-colony stimulating factor is sufficient for both human and mouse osteoclast formation in vitro. Endocrinology 1998; 139: 4424-4427.
    • (1998) Endocrinology , vol.139 , pp. 4424-4427
    • Quinn, J.M.1    Elliott, J.2    Gillespie, M.T.3    Martin, T.J.4
  • 33
    • 0033398996 scopus 로고    scopus 로고
    • Commitment and differentiation of osteoclast precursor cells by the sequential expression of c-Fms and receptor activator of nuclear factor kappaB (RANK) receptors
    • Arai F, Miyamoto T, Ohneda O, et al. Commitment and differentiation of osteoclast precursor cells by the sequential expression of c-Fms and receptor activator of nuclear factor kappaB (RANK) receptors. J Exp Med 1999; 190: 1741-1754.
    • (1999) J Exp Med , vol.190 , pp. 1741-1754
    • Arai, F.1    Miyamoto, T.2    Ohneda, O.3
  • 34
    • 80053938104 scopus 로고    scopus 로고
    • Evidence for osteocyte regulation of bone homeostasis through RANKL expression
    • Nakashima T, Hayashi M, Fukunaga T, et al. Evidence for osteocyte regulation of bone homeostasis through RANKL expression. Nat Med 2011; 17: 1231-1234.
    • (2011) Nat Med , vol.17 , pp. 1231-1234
    • Nakashima, T.1    Hayashi, M.2    Fukunaga, T.3
  • 35
    • 0033984313 scopus 로고    scopus 로고
    • The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption
    • Hofbauer LC, Khosla S, Dunstan CR, Lacey DL, Boyle WJ, Riggs BL. The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption. J Bone Miner Res 2000; 15: 2-12.
    • (2000) J Bone Miner Res , vol.15 , pp. 2-12
    • Hofbauer, L.C.1    Khosla, S.2    Dunstan, C.R.3    Lacey, D.L.4    Boyle, W.J.5    Riggs, B.L.6
  • 36
    • 0031005576 scopus 로고    scopus 로고
    • Osteoprotegerin: A novel secreted protein involved in the regulation of bone density
    • Simonet WS, Lacey DL, Dunstan CR, et al. Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. Cell 1997; 89: 309-319.
    • (1997) Cell , vol.89 , pp. 309-319
    • Simonet, W.S.1    Lacey, D.L.2    Dunstan, C.R.3
  • 37
    • 0035008944 scopus 로고    scopus 로고
    • Dual regulation of osteoclast differentiation by periodontal ligament cells through RANKL stimulation and OPG inhibition
    • Kanzaki H, Chiba M, Shimizu Y, Mitani H. Dual regulation of osteoclast differentiation by periodontal ligament cells through RANKL stimulation and OPG inhibition. J Dent Res 2001; 80: 887-891.
    • (2001) J Dent Res , vol.80 , pp. 887-891
    • Kanzaki, H.1    Chiba, M.2    Shimizu, Y.3    Mitani, H.4
  • 38
    • 0032836025 scopus 로고    scopus 로고
    • Expression of osteoprotegerin (osteoclastogenesis inhibitory factor) in cultures of human dental mesenchymal cells and epithelial cells
    • Sakata M, Shiba H, Komatsuzawa H, et al. Expression of osteoprotegerin (osteoclastogenesis inhibitory factor) in cultures of human dental mesenchymal cells and epithelial cells. J Bone Miner Res 1999; 14: 1486-1492.
    • (1999) J Bone Miner Res , vol.14 , pp. 1486-1492
    • Sakata, M.1    Shiba, H.2    Komatsuzawa, H.3
  • 39
    • 0242668869 scopus 로고    scopus 로고
    • Bone morphogenetic proteins, their antagonists, and the skeleton
    • Canalis E, Economides AN, Gazzerro E. Bone morphogenetic proteins, their antagonists, and the skeleton. Endocr Rev 2003; 24: 218-235.
    • (2003) Endocr Rev , vol.24 , pp. 218-235
    • Canalis, E.1    Economides, A.N.2    Gazzerro, E.3
  • 40
    • 33745173528 scopus 로고    scopus 로고
    • Osteoblasts provide a suitable microenvironment for the action of receptor activator of nuclear factor-kappaB ligand
    • Yamamoto Y, Udagawa N, Matsuura S, et al. Osteoblasts provide a suitable microenvironment for the action of receptor activator of nuclear factor-kappaB ligand. Endocrinology 2006; 147: 3366-3374.
    • (2006) Endocrinology , vol.147 , pp. 3366-3374
    • Yamamoto, Y.1    Udagawa, N.2    Matsuura, S.3
  • 41
    • 81255211982 scopus 로고    scopus 로고
    • Targeting osteoclast-osteoblast communication
    • Cao X. Targeting osteoclast-osteoblast communication. Nat Med 2011; 17: 1344-1346.
    • (2011) Nat Med , vol.17 , pp. 1344-1346
    • Cao, X.1
  • 42
    • 0033768860 scopus 로고    scopus 로고
    • Osteoclasts, integrins, and osteoporosis
    • Teitelbaum SL. Osteoclasts, integrins, and osteoporosis. J Bone Miner Metab 2000; 18: 344-349.
    • (2000) J Bone Miner Metab , vol.18 , pp. 344-349
    • Teitelbaum, S.L.1
  • 43
    • 33748788554 scopus 로고    scopus 로고
    • B and T lymphocytes are the primary sources of RANKL in the bone resorptive lesion of periodontal disease
    • Kawai T, Matsuyama T, Hosokawa Y, et al. B and T lymphocytes are the primary sources of RANKL in the bone resorptive lesion of periodontal disease. Am J Pathol 2006; 169: 987-998.
    • (2006) Am J Pathol , vol.169 , pp. 987-998
    • Kawai, T.1    Matsuyama, T.2    Hosokawa, Y.3
  • 44
    • 84877777006 scopus 로고    scopus 로고
    • Future prospects of systemic host modulatory agents in periodontal therapy
    • Gokhale SR, Padhye AM. Future prospects of systemic host modulatory agents in periodontal therapy. Br Dent J 2013; 214: 467-471.
    • (2013) Br Dent J , vol.214 , pp. 467-471
    • Gokhale, S.R.1    Padhye, A.M.2
  • 45
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature 1998; 392: 245-252.
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 46
    • 77349105277 scopus 로고    scopus 로고
    • Instructive cytokine signals in dendritic cell lineage commitment
    • Schmid MA, Kingston D, Boddupalli S, Manz MG. Instructive cytokine signals in dendritic cell lineage commitment. Immunol Rev 2010; 234: 32-44.
    • (2010) Immunol Rev , vol.234 , pp. 32-44
    • Schmid, M.A.1    Kingston, D.2    Boddupalli, S.3    Manz, M.G.4
  • 47
    • 65249089638 scopus 로고    scopus 로고
    • In vivo analysis of dendritic cell development and homeostasis
    • Liu K, Victora GD, Schwickert TA, et al. In vivo analysis of dendritic cell development and homeostasis. Science 2009; 324: 392-397.
    • (2009) Science , vol.324 , pp. 392-397
    • Liu, K.1    Victora, G.D.2    Schwickert, T.A.3
  • 48
    • 0037988844 scopus 로고    scopus 로고
    • The lymphoid past of mouse plasmacytoid cells and thymic dendritic cells
    • Corcoran L, Ferrero I, Vremec D, et al. The lymphoid past of mouse plasmacytoid cells and thymic dendritic cells. J Immunol 2003; 170: 4926-4932.
    • (2003) J Immunol , vol.170 , pp. 4926-4932
    • Corcoran, L.1    Ferrero, I.2    Vremec, D.3
  • 49
    • 15244349785 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells in immunity
    • Colonna M, Trinchieri G, Liu YJ. Plasmacytoid dendritic cells in immunity. Nature Immunol 2004; 5: 1219-1226.
    • (2004) Nature Immunol , vol.5 , pp. 1219-1226
    • Colonna, M.1    Trinchieri, G.2    Liu, Y.J.3
  • 50
    • 34548591274 scopus 로고    scopus 로고
    • Oral mucosal dendritic cells and periodontitis: Many sides of the same coin with new twists
    • Cutler CW, Teng YT. Oral mucosal dendritic cells and periodontitis: many sides of the same coin with new twists. Periodontology 2000 2007; 45: 35-50.
    • (2007) Periodontology 2000 , Issue.45 , pp. 35-50
    • Cutler, C.W.1    Teng, Y.T.2
  • 51
    • 80052722890 scopus 로고    scopus 로고
    • IL-23-producing CD68(+) macrophage-like cells predominate within an IL-17-polarized infiltrate in chronic periodontitis lesions
    • Allam JP, Duan Y, Heinemann F, et al. IL-23-producing CD68(+) macrophage-like cells predominate within an IL-17-polarized infiltrate in chronic periodontitis lesions. J Clin Periodontol 2011; 38: 879-886.
    • (2011) J Clin Periodontol , vol.38 , pp. 879-886
    • Allam, J.P.1    Duan, Y.2    Heinemann, F.3
  • 52
    • 28544446111 scopus 로고    scopus 로고
    • Monocyte and macrophage heterogeneity
    • Gordon S, Taylor PR. Monocyte and macrophage heterogeneity. Nat Revs Immunol 2005; 5: 953-964.
    • (2005) Nat Revs Immunol , vol.5 , pp. 953-964
    • Gordon, S.1    Taylor, P.R.2
  • 53
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • Mosser DM, Edwards JP. Exploring the full spectrum of macrophage activation. Nat Rev Immunol 2008; 8: 958-969.
    • (2008) Nat Rev Immunol , vol.8 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 55
    • 79952622012 scopus 로고    scopus 로고
    • Immunohistochemical analysis of inflammatory infiltrate in aggressive and chronic periodontitis: A comparative study
    • Artese L, Simon MJ, Piattelli A, et al. Immunohistochemical analysis of inflammatory infiltrate in aggressive and chronic periodontitis: a comparative study. Clin Oral Investig 2011; 15: 233-240.
    • (2011) Clin Oral Investig , vol.15 , pp. 233-240
    • Artese, L.1    Simon, M.J.2    Piattelli, A.3
  • 56
    • 0034681337 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha induces differentiation of and bone resorption by osteoclasts
    • Azuma Y, Kaji K, Katogi R, Takeshita S, Kudo A. Tumor necrosis factor-alpha induces differentiation of and bone resorption by osteoclasts. J Biol Chem 2000; 275: 4858-4864.
    • (2000) J Biol Chem , vol.275 , pp. 4858-4864
    • Azuma, Y.1    Kaji, K.2    Katogi, R.3    Takeshita, S.4    Kudo, A.5
  • 57
    • 0038505147 scopus 로고    scopus 로고
    • The contribution of interleukin-1 and tumor necrosis factor to periodontal tissue destruction
    • Graves DT, Cochran D. The contribution of interleukin-1 and tumor necrosis factor to periodontal tissue destruction. J Periodontol 2003; 74: 391-401.
    • (2003) J Periodontol , vol.74 , pp. 391-401
    • Graves, D.T.1    Cochran, D.2
  • 58
    • 0032468328 scopus 로고    scopus 로고
    • Cytokine expression in periodontal health and disease
    • Okada H, Murakami S. Cytokine expression in periodontal health and disease. Crit Rev Oral Biol Med 1998; 9: 248-266.
    • (1998) Crit Rev Oral Biol Med , vol.9 , pp. 248-266
    • Okada, H.1    Murakami, S.2
  • 59
    • 0034677177 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction
    • Kobayashi K, Takahashi N, Jimi E, et al. Tumor necrosis factor alpha stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction. J Exp Med 2000; 191: 275-286.
    • (2000) J Exp Med , vol.191 , pp. 275-286
    • Kobayashi, K.1    Takahashi, N.2    Jimi, E.3
  • 60
    • 54949126342 scopus 로고    scopus 로고
    • How antirheumatic drugs protect joints from damage in rheumatoid arthritis
    • Schett G, Stach C, Zwerina J, Voll R, Manger B. How antirheumatic drugs protect joints from damage in rheumatoid arthritis. Arthritis Rheum 2008; 58: 2936-2948.
    • (2008) Arthritis Rheum , vol.58 , pp. 2936-2948
    • Schett, G.1    Stach, C.2    Zwerina, J.3    Voll, R.4    Manger, B.5
  • 61
    • 4444296374 scopus 로고    scopus 로고
    • A possible association between preterm birth and early periodontitis. A pilot study
    • Radnai M, Gorzo I, Nagy E, Urban E, Novak T, Pal A. A possible association between preterm birth and early periodontitis. A pilot study. J Clin Periodontol 2004; 31: 736-741.
    • (2004) J Clin Periodontol , vol.31 , pp. 736-741
    • Radnai, M.1    Gorzo, I.2    Nagy, E.3    Urban, E.4    Novak, T.5    Pal, A.6
  • 62
    • 34248136828 scopus 로고    scopus 로고
    • Inflammatory bowel disease: Cause and immunobiology
    • Baumgart DC, Carding SR. Inflammatory bowel disease: cause and immunobiology. Lancet 2007; 369: 1627-1640.
    • (2007) Lancet , vol.369 , pp. 1627-1640
    • Baumgart, D.C.1    Carding, S.R.2
  • 63
    • 0036284984 scopus 로고    scopus 로고
    • The role of Th1/Th2 polarization in mucosal immunity
    • Neurath MF, Finotto S, Glimcher LH. The role of Th1/Th2 polarization in mucosal immunity. Nat Med 2002; 8: 567-573.
    • (2002) Nat Med , vol.8 , pp. 567-573
    • Neurath, M.F.1    Finotto, S.2    Glimcher, L.H.3
  • 64
    • 0022640843 scopus 로고
    • Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
    • Mosmann TR, Cherwinski H, Bond MW, Giedlin MA, Coffman RL. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 1986; 136: 2348-2357.
    • (1986) J Immunol , vol.136 , pp. 2348-2357
    • Mosmann, T.R.1    Cherwinski, H.2    Bond, M.W.3    Giedlin, M.A.4    Coffman, R.L.5
  • 65
    • 13244283212 scopus 로고    scopus 로고
    • IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
    • Langrish CL, Chen Y, Blumenschein WM, et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med 2005; 201: 233-240.
    • (2005) J Exp Med , vol.201 , pp. 233-240
    • Langrish, C.L.1    Chen, Y.2    Blumenschein, W.M.3
  • 66
    • 0027249369 scopus 로고
    • The involvement of T cell receptor peptide-specific regulatory CD4+ T cells in recovery from antigen-induced autoimmune disease
    • Kumar V, Sercarz EE. The involvement of T cell receptor peptide-specific regulatory CD4+ T cells in recovery from antigen-induced autoimmune disease. J Exp Med 1993; 178: 909-916.
    • (1993) J Exp Med , vol.178 , pp. 909-916
    • Kumar, V.1    Sercarz, E.E.2
  • 67
    • 0034661356 scopus 로고    scopus 로고
    • Lineage commitment in the immune system: The T helper lymphocyte grows up
    • Glimcher LH, Murphy KM. Lineage commitment in the immune system: the T helper lymphocyte grows up. Genes Dev 2000; 14: 1693-1711.
    • (2000) Genes Dev , vol.14 , pp. 1693-1711
    • Glimcher, L.H.1    Murphy, K.M.2
  • 68
    • 0031172781 scopus 로고    scopus 로고
    • The Th1/Th2 paradigm
    • Romagnani S. The Th1/Th2 paradigm. Immunol Today 1997; 18: 263-266.
    • (1997) Immunol Today , vol.18 , pp. 263-266
    • Romagnani, S.1
  • 69
    • 0035041537 scopus 로고    scopus 로고
    • Regulation of IL-4 gene expression by distal regulatory elements and GATA-3 at the chromatin level
    • Lee GR, Fields PE, Flavell RA. Regulation of IL-4 gene expression by distal regulatory elements and GATA-3 at the chromatin level. Immunity 2001; 14: 447-459.
    • (2001) Immunity , vol.14 , pp. 447-459
    • Lee, G.R.1    Fields, P.E.2    Flavell, R.A.3
  • 70
    • 0033973582 scopus 로고    scopus 로고
    • Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment
    • Ouyang W, Lohning M, Gao Z, et al. Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment. Immunity 2000; 12: 27-37.
    • (2000) Immunity , vol.12 , pp. 27-37
    • Ouyang, W.1    Lohning, M.2    Gao, Z.3
  • 71
    • 33646164439 scopus 로고    scopus 로고
    • Expanding the effector CD4 T-cell repertoire: The Th17 lineage
    • Harrington LE, Mangan PR, Weaver CT. Expanding the effector CD4 T-cell repertoire: the Th17 lineage. Curr Opin Immunol 2006; 18: 349-356.
    • (2006) Curr Opin Immunol , vol.18 , pp. 349-356
    • Harrington, L.E.1    Mangan, P.R.2    Weaver, C.T.3
  • 72
    • 35748981184 scopus 로고    scopus 로고
    • Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants
    • Burton PR, Clayton DG, Cardon LR, et al. Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet 2007; 39: 1329-1337.
    • (2007) Nat Genet , vol.39 , pp. 1329-1337
    • Burton, P.R.1    Clayton, D.G.2    Cardon, L.R.3
  • 73
    • 0347285359 scopus 로고    scopus 로고
    • Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris
    • Lee E, Trepicchio WL, Oestreicher JL, et al. Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris. J Exp Med 2004; 199: 125-130.
    • (2004) J Exp Med , vol.199 , pp. 125-130
    • Lee, E.1    Trepicchio, W.L.2    Oestreicher, J.L.3
  • 74
    • 41549134361 scopus 로고    scopus 로고
    • Th17 cell differentiation: The long and winding road
    • McGeachy MJ, Cua DJ. Th17 cell differentiation: the long and winding road. Immunity 2008; 28: 445-453.
    • (2008) Immunity , vol.28 , pp. 445-453
    • McGeachy, M.J.1    Cua, D.J.2
  • 75
    • 34548133583 scopus 로고    scopus 로고
    • Development, cytokine profile and function of human interleukin 17-producing helper T cells
    • Wilson NJ, Boniface K, Chan JR, et al. Development, cytokine profile and function of human interleukin 17-producing helper T cells. Nat Immunol 2007; 8: 950-957.
    • (2007) Nat Immunol , vol.8 , pp. 950-957
    • Wilson, N.J.1    Boniface, K.2    Chan, J.R.3
  • 76
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
    • Bettelli E, Carrier Y, Gao W, et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 2006; 441: 235-238.
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3
  • 77
    • 34547232503 scopus 로고    scopus 로고
    • IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells
    • Korn T, Bettelli E, Gao W, et al. IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells. Nature 2007; 448: 484-487.
    • (2007) Nature , vol.448 , pp. 484-487
    • Korn, T.1    Bettelli, E.2    Gao, W.3
  • 78
    • 34247555353 scopus 로고    scopus 로고
    • Differentiation and function of Th17 T cells
    • Stockinger B, Veldhoen M. Differentiation and function of Th17 T cells. Curr Opin Immunol 2007; 19: 281-286.
    • (2007) Curr Opin Immunol , vol.19 , pp. 281-286
    • Stockinger, B.1    Veldhoen, M.2
  • 79
    • 33745873727 scopus 로고    scopus 로고
    • A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis
    • Sutton C, Brereton C, Keogh B, Mills KH, Lavelle EC. A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis. J Exp Med 2006; 203: 1685-1691.
    • (2006) J Exp Med , vol.203 , pp. 1685-1691
    • Sutton, C.1    Brereton, C.2    Keogh, B.3    Mills, K.H.4    Lavelle, E.C.5
  • 80
    • 29144513556 scopus 로고    scopus 로고
    • Fas ligand induces cell-autonomous IL-23 production in dendritic cells, a mechanism for Fas ligand-induced IL-17 production
    • Kidoya H, Umemura M, Kawabe T, et al. Fas ligand induces cell-autonomous IL-23 production in dendritic cells, a mechanism for Fas ligand-induced IL-17 production. J Immunol 2005; 175: 8024-8031.
    • (2005) J Immunol , vol.175 , pp. 8024-8031
    • Kidoya, H.1    Umemura, M.2    Kawabe, T.3
  • 81
    • 44049104564 scopus 로고    scopus 로고
    • The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat
    • Manel N, Unutmaz D, Littman DR. The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat. Nat Immunol 2008; 9: 641-649.
    • (2008) Nat Immunol , vol.9 , pp. 641-649
    • Manel, N.1    Unutmaz, D.2    Littman, D.R.3
  • 82
    • 44049102724 scopus 로고    scopus 로고
    • A critical function for transforming growth factor-beta, interleukin 23 and proinflammatory cytokines in driving and modulating human T(H)-17 responses
    • Volpe E, Servant N, Zollinger R, et al. A critical function for transforming growth factor-beta, interleukin 23 and proinflammatory cytokines in driving and modulating human T(H)-17 responses. Nat Immunol 2008; 9: 650-657.
    • (2008) Nat Immunol , vol.9 , pp. 650-657
    • Volpe, E.1    Servant, N.2    Zollinger, R.3
  • 84
    • 55149112367 scopus 로고    scopus 로고
    • The interleukin-23 axis in intestinal inflammation
    • Ahern PP, Izcue A, Maloy KJ, Powrie F. The interleukin-23 axis in intestinal inflammation. Immunol Rev 2008; 226: 147-159.
    • (2008) Immunol Rev , vol.226 , pp. 147-159
    • Ahern, P.P.1    Izcue, A.2    Maloy, K.J.3    Powrie, F.4
  • 85
    • 83555163767 scopus 로고    scopus 로고
    • Functional relevance of T helper 17 (Th17) cells and the IL-17 cytokine family in inflammatory bowel disease
    • Hundorfean G, Neurath MF, Mudter J. Functional relevance of T helper 17 (Th17) cells and the IL-17 cytokine family in inflammatory bowel disease. Inflamm Bowel Dis 2012; 18: 180-186.
    • (2012) Inflamm Bowel Dis , vol.18 , pp. 180-186
    • Hundorfean, G.1    Neurath, M.F.2    Mudter, J.3
  • 86
    • 84856603151 scopus 로고    scopus 로고
    • Th17 cells: Interactions with predisposing factors in the immunopathogenesis of inflammatory bowel disease
    • Raza A, Yousaf W, Giannella R, Shata MT. Th17 cells: interactions with predisposing factors in the immunopathogenesis of inflammatory bowel disease. Expert Rev Clin Immunol 2012; 8: 161-168.
    • (2012) Expert Rev Clin Immunol , vol.8 , pp. 161-168
    • Raza, A.1    Yousaf, W.2    Giannella, R.3    Shata, M.T.4
  • 88
    • 68249143144 scopus 로고    scopus 로고
    • The involvement of IL-23 and the Th17 pathway in periodontitis
    • Ohyama H, Kato-Kogoe N, Kuhara A, et al. The involvement of IL-23 and the Th17 pathway in periodontitis. J Dent Res 2009; 88: 633-638.
    • (2009) J Dent Res , vol.88 , pp. 633-638
    • Ohyama, H.1    Kato-Kogoe, N.2    Kuhara, A.3
  • 89
    • 33751521013 scopus 로고    scopus 로고
    • Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction
    • Sato K, Suematsu A, Okamoto K, et al. Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction. J Exp Med 2006; 203: 2673-2682.
    • (2006) J Exp Med , vol.203 , pp. 2673-2682
    • Sato, K.1    Suematsu, A.2    Okamoto, K.3
  • 90
    • 33947583822 scopus 로고    scopus 로고
    • Osteoimmunology: Shared mechanisms and crosstalk between the immune and bone systems
    • Takayanagi H. Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems. Nat Rev 2007; 7: 292-304.
    • (2007) Nat Rev , vol.7 , pp. 292-304
    • Takayanagi, H.1
  • 91
    • 33646417072 scopus 로고    scopus 로고
    • The IL-23/IL-17 axis in inflammation
    • Iwakura Y, Ishigame H. The IL-23/IL-17 axis in inflammation. J Clin Invest 2006; 116: 1218-1222.
    • (2006) J Clin Invest , vol.116 , pp. 1218-1222
    • Iwakura, Y.1    Ishigame, H.2
  • 92
    • 0032055597 scopus 로고    scopus 로고
    • IL-17 stimulates the production and expression of proinflammatory cytokines, IL-beta and TNF-alpha, by human macrophages
    • Jovanovic D V, Di Battista JA, Martel-Pelletier J, et al. IL-17 stimulates the production and expression of proinflammatory cytokines, IL-beta and TNF-alpha, by human macrophages. J Immunol 1998; 160: 3513-3521.
    • (1998) J Immunol , vol.160 , pp. 3513-3521
    • Jovanovic, D.V.1    Di Battista, J.A.2    Martel-Pelletier, J.3
  • 93
    • 47249125726 scopus 로고    scopus 로고
    • Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes
    • Pene J, Chevalier S, Preisser L, et al. Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes. J Immunol 2008; 180: 7423-7430.
    • (2008) J Immunol , vol.180 , pp. 7423-7430
    • Pene, J.1    Chevalier, S.2    Preisser, L.3
  • 94
    • 0027163182 scopus 로고
    • CD4+ T cells that express high levels of CD45RB induce wasting disease when transferred into congenic severe combined immunodeficient mice. Disease development is prevented by cotransfer of purified CD4+ T cell
    • Morrissey PJ, Charrier K, Braddy S, Liggitt D, Watson JD. CD4+ T cells that express high levels of CD45RB induce wasting disease when transferred into congenic severe combined immunodeficient mice. Disease development is prevented by cotransfer of purified CD4+ T cells. J Exp Med 1993; 178: 237-244.
    • (1993) J Exp Med , vol.178 , pp. 237-244
    • Morrissey, P.J.1    Charrier, K.2    Braddy, S.3    Liggitt, D.4    Watson, J.D.5
  • 95
    • 0027517545 scopus 로고
    • Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice
    • Powrie F, Leach MW, Mauze S, Caddle LB, Coffman RL. Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice. Int Immunol 1993; 5: 1461-1471.
    • (1993) Int Immunol , vol.5 , pp. 1461-1471
    • Powrie, F.1    Leach, M.W.2    Mauze, S.3    Caddle, L.B.4    Coffman, R.L.5
  • 96
    • 2442484053 scopus 로고    scopus 로고
    • Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses
    • Sakaguchi S. Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol 2004; 22: 531-562.
    • (2004) Annu Rev Immunol , vol.22 , pp. 531-562
    • Sakaguchi, S.1
  • 97
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • Fontenot JD, Gavin MA, Rudensky AY. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 2003; 4: 330-336.
    • (2003) Nat Immunol , vol.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 98
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003; 299: 1057-1061.
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 99
    • 0037385314 scopus 로고    scopus 로고
    • An essential role for Scurfin in CD4+CD25+ T regulatory cells
    • Khattri R, Cox T, Yasayko SA, Ramsdell F. An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat Immunol 2003; 4: 337-342.
    • (2003) Nat Immunol , vol.4 , pp. 337-342
    • Khattri, R.1    Cox, T.2    Yasayko, S.A.3    Ramsdell, F.4
  • 100
    • 0034967640 scopus 로고    scopus 로고
    • Differential cytokine requirements for regulation of autoimmune gastritis and colitis by CD4(+)CD25(+) T cells
    • Suri-Payer E, Cantor H. Differential cytokine requirements for regulation of autoimmune gastritis and colitis by CD4(+)CD25(+) T cells. J Autoimmun 2001; 16: 115-123.
    • (2001) J Autoimmun , vol.16 , pp. 115-123
    • Suri-Payer, E.1    Cantor, H.2
  • 101
    • 23944484088 scopus 로고    scopus 로고
    • Regulatory T-cells infiltrate periodontal disease tissues
    • Nakajima T, Ueki-Maruyama K, Oda T, et al. Regulatory T-cells infiltrate periodontal disease tissues. J Dent Res 2005; 84: 639-643.
    • (2005) J Dent Res , vol.84 , pp. 639-643
    • Nakajima, T.1    Ueki-Maruyama, K.2    Oda, T.3
  • 102
    • 84899517394 scopus 로고    scopus 로고
    • Porphyromonas gingivalis infection reduces regulatory T cells in infected atherosclerosis patients
    • Yang J, Wu J, Liu Y, et al. Porphyromonas gingivalis infection reduces regulatory T cells in infected atherosclerosis patients. PLoS One 2014; 9: e86599.
    • (2014) PLoS One , vol.9
    • Yang, J.1    Wu, J.2    Liu, Y.3
  • 103
    • 77953573811 scopus 로고    scopus 로고
    • Regulatory T cells attenuate experimental periodontitis progression in mice
    • Garlet G P, Cardoso CR, Mariano FS, et al. Regulatory T cells attenuate experimental periodontitis progression in mice. J Clin Periodontol 2010; 37: 591-600.
    • (2010) J Clin Periodontol , vol.37 , pp. 591-600
    • Garlet, G.P.1    Cardoso, C.R.2    Mariano, F.S.3
  • 104
    • 79955835477 scopus 로고    scopus 로고
    • Induction of IL-10-producing CD4+ T-cells in chronic periodontitis
    • Kobayashi R, Kono T, Bolerjack BA, et al. Induction of IL-10-producing CD4+ T-cells in chronic periodontitis. J Dent Res 2011; 90: 653-658.
    • (2011) J Dent Res , vol.90 , pp. 653-658
    • Kobayashi, R.1    Kono, T.2    Bolerjack, B.A.3
  • 105
    • 84901477903 scopus 로고    scopus 로고
    • Oral administration of all-trans retinoic acid suppresses experimental periodontitis by modulating the Th17/Treg imbalance
    • Wang L, Wang J, Jin Y, Gao H, Lin X. Oral administration of all-trans retinoic acid suppresses experimental periodontitis by modulating the Th17/Treg imbalance. J Periodontol 2014; 85: 740-750.
    • (2014) J Periodontol , vol.85 , pp. 740-750
    • Wang, L.1    Wang, J.2    Jin, Y.3    Gao, H.4    Lin, X.5
  • 106
    • 0034988303 scopus 로고    scopus 로고
    • Bone marrow stromal stem cells: Nature, biology, and potential applications
    • Bianco P, Riminucci M, Gronthos S, Robey PG. Bone marrow stromal stem cells: nature, biology, and potential applications. Stem Cells 2001; 19: 180-192.
    • (2001) Stem Cells , vol.19 , pp. 180-192
    • Bianco, P.1    Riminucci, M.2    Gronthos, S.3    Robey, P.G.4
  • 107
    • 0030889354 scopus 로고    scopus 로고
    • Marrow stromal cells as stem cells for nonhematopoietic tissues
    • Prockop DJ. Marrow stromal cells as stem cells for nonhematopoietic tissues. Science 1997; 276: 71-74.
    • (1997) Science , vol.276 , pp. 71-74
    • Prockop, D.J.1
  • 108
    • 2442464824 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Paradoxes of passaging
    • Javazon EH, Beggs KJ, Flake AW. Mesenchymal stem cells: paradoxes of passaging. Exp Hematol 2004; 32: 414-425.
    • (2004) Exp Hematol , vol.32 , pp. 414-425
    • Javazon, E.H.1    Beggs, K.J.2    Flake, A.W.3
  • 109
    • 0037125643 scopus 로고    scopus 로고
    • The therapeutic potential of stem cells from adults
    • Kuehnle I, Goodell MA. The therapeutic potential of stem cells from adults. BMJ 2002; 325: 372-376.
    • (2002) BMJ , vol.325 , pp. 372-376
    • Kuehnle, I.1    Goodell, M.A.2
  • 110
    • 17444410347 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Progress toward promise
    • Le Blanc K, Pittenger M. Mesenchymal stem cells: progress toward promise. Cytotherapy 2005; 7: 36-45.
    • (2005) Cytotherapy , vol.7 , pp. 36-45
    • Le Blanc, K.1    Pittenger, M.2
  • 112
    • 77955868215 scopus 로고    scopus 로고
    • Differentiation potential of stem cells from human dental origin - promise for tissue engineering
    • Kadar K, Kiraly M, Porcsalmy B, et al. Differentiation potential of stem cells from human dental origin - promise for tissue engineering. J Physiol Pharmacol 2009; 60 (Suppl. 7): 167-175.
    • (2009) J Physiol Pharmacol , vol.60 , Issue.SUPPL. 7 , pp. 167-175
    • Kadar, K.1    Kiraly, M.2    Porcsalmy, B.3
  • 113
    • 67649342187 scopus 로고    scopus 로고
    • Simultaneous PKC and cAMP activation induces differentiation of human dental pulp stem cells into functionally active neurons
    • Kiraly M, Porcsalmy B, Pataki A, et al. Simultaneous PKC and cAMP activation induces differentiation of human dental pulp stem cells into functionally active neurons. Neurochem Int 2009; 55: 323-332.
    • (2009) Neurochem Int , vol.55 , pp. 323-332
    • Kiraly, M.1    Porcsalmy, B.2    Pataki, A.3
  • 114
    • 0037687418 scopus 로고    scopus 로고
    • SHED: Stem cells from human exfoliated deciduous teeth
    • Miura M, Gronthos S, Zhao M, et al. SHED: stem cells from human exfoliated deciduous teeth. Proc Natl Acad Sci USA 2003; 100: 5807-5812.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 5807-5812
    • Miura, M.1    Gronthos, S.2    Zhao, M.3
  • 115
    • 3042749378 scopus 로고    scopus 로고
    • Investigation of multipotent postnatal stem cells from human periodontal ligament
    • Seo BM, Miura M, Gronthos S, et al. Investigation of multipotent postnatal stem cells from human periodontal ligament. Lancet 2004; 364: 149-155.
    • (2004) Lancet , vol.364 , pp. 149-155
    • Seo, B.M.1    Miura, M.2    Gronthos, S.3
  • 116
    • 73349121988 scopus 로고    scopus 로고
    • Isolating, culturing and characterizing stem cells of human dental pulp origin [in Hungarian]
    • Kadar K, Porcsalmy B, Kiraly M, et al. Isolating, culturing and characterizing stem cells of human dental pulp origin [in Hungarian]. Fogorv Sz 2009; 102: 175-181.
    • (2009) Fogorv Sz , vol.102 , pp. 175-181
    • Kadar, K.1    Porcsalmy, B.2    Kiraly, M.3
  • 117
    • 0033593654 scopus 로고    scopus 로고
    • Turning brain into blood: A hematopoietic fate adopted by adult neural stem cells in vivo
    • Bjornson CR, Rietze RL, Reynolds BA, Magli MC, Vescovi AL. Turning brain into blood: a hematopoietic fate adopted by adult neural stem cells in vivo. Science 1999; 283: 534-537.
    • (1999) Science , vol.283 , pp. 534-537
    • Bjornson, C.R.1    Rietze, R.L.2    Reynolds, B.A.3    Magli, M.C.4    Vescovi, A.L.5
  • 118
    • 0034595855 scopus 로고    scopus 로고
    • Generalized potential of adult neural stem cells
    • Clarke DL, Johansson CB, Wilbertz J, et al. Generalized potential of adult neural stem cells. Science 2000; 288: 1660-1663.
    • (2000) Science , vol.288 , pp. 1660-1663
    • Clarke, D.L.1    Johansson, C.B.2    Wilbertz, J.3
  • 119
    • 0033804048 scopus 로고    scopus 로고
    • Skeletal myogenic potential of human and mouse neural stem cells
    • Galli R, Borello U, Gritti A, et al. Skeletal myogenic potential of human and mouse neural stem cells. Nat Neurosci 2000; 3: 986-991.
    • (2000) Nat Neurosci , vol.3 , pp. 986-991
    • Galli, R.1    Borello, U.2    Gritti, A.3
  • 121
    • 0033515827 scopus 로고    scopus 로고
    • Multilineage potential of adult human mesenchymal stem cells
    • Pittenger MF, Mackay AM, Beck SC, et al. Multilineage potential of adult human mesenchymal stem cells. Science 1999; 284: 143-147.
    • (1999) Science , vol.284 , pp. 143-147
    • Pittenger, M.F.1    Mackay, A.M.2    Beck, S.C.3
  • 122
    • 58149288581 scopus 로고    scopus 로고
    • Isolation, cultivation and characterisation of stem cells in human periodontal ligament [in Hungarian]
    • Molnar B, Kadar K, Kiraly M, et al. Isolation, cultivation and characterisation of stem cells in human periodontal ligament [in Hungarian]. Fogorv Sz 2008; 101: 155-161.
    • (2008) Fogorv Sz , vol.101 , pp. 155-161
    • Molnar, B.1    Kadar, K.2    Kiraly, M.3
  • 123
    • 80555129675 scopus 로고    scopus 로고
    • Isolation and characterization of neural crest-derived stem cells from dental pulp of neonatal mice
    • Janebodin K, Horst O V, Ieronimakis N, et al. Isolation and characterization of neural crest-derived stem cells from dental pulp of neonatal mice. PLoS One 2011; 6: e27526.
    • (2011) PLoS One , vol.6
    • Janebodin, K.1    Horst, O.V.2    Ieronimakis, N.3
  • 125
    • 79952505963 scopus 로고    scopus 로고
    • Immunomodulatory properties and therapeutic application of mesenchymal stem cells
    • Shi M, Liu ZW, Wang FS. Immunomodulatory properties and therapeutic application of mesenchymal stem cells. Clin Exp Immunol 2011; 164: 1-8.
    • (2011) Clin Exp Immunol , vol.164 , pp. 1-8
    • Shi, M.1    Liu, Z.W.2    Wang, F.S.3
  • 126
    • 33745231146 scopus 로고    scopus 로고
    • Immune modulation by mesenchymal stem cells
    • Rasmusson I. Immune modulation by mesenchymal stem cells. Exp Cell Res 2006; 312: 2169-2179.
    • (2006) Exp Cell Res , vol.312 , pp. 2169-2179
    • Rasmusson, I.1
  • 127
    • 33750233770 scopus 로고    scopus 로고
    • Immunoregulatory function of mesenchymal stem cells
    • Uccelli A, Moretta L, Pistoia V. Immunoregulatory function of mesenchymal stem cells. Eur J Immunol 2006; 36: 2566-2573.
    • (2006) Eur J Immunol , vol.36 , pp. 2566-2573
    • Uccelli, A.1    Moretta, L.2    Pistoia, V.3
  • 128
    • 84870222961 scopus 로고    scopus 로고
    • From bone marrow transplantation to cellular therapies: Possible therapeutic strategies in managing autoimmune disorders
    • Taddio A, Biondi A, Piscianz E, Valencic E, Biagi E, Badolato R. From bone marrow transplantation to cellular therapies: possible therapeutic strategies in managing autoimmune disorders. Curr Pharm Design 2012; 18: 5776-5781.
    • (2012) Curr Pharm Design , vol.18 , pp. 5776-5781
    • Taddio, A.1    Biondi, A.2    Piscianz, E.3    Valencic, E.4    Biagi, E.5    Badolato, R.6
  • 129
    • 0037093058 scopus 로고    scopus 로고
    • Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli
    • Di Nicola M, Carlo-Stella C, Magni M, et al. Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. Blood 2002; 99: 3838-3843.
    • (2002) Blood , vol.99 , pp. 3838-3843
    • Di Nicola, M.1    Carlo-Stella, C.2    Magni, M.3
  • 130
    • 0038204193 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide
    • Krampera M, Glennie S, Dyson J, et al. Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide. Blood 2003; 101: 3722-3729.
    • (2003) Blood , vol.101 , pp. 3722-3729
    • Krampera, M.1    Glennie, S.2    Dyson, J.3
  • 131
    • 0042740515 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex
    • Le Blanc K, Tammik L, Sundberg B, Haynesworth SE, Ringden O. Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex. Scand J Immunol 2003; 57: 11-20.
    • (2003) Scand J Immunol , vol.57 , pp. 11-20
    • Le Blanc, K.1    Tammik, L.2    Sundberg, B.3    Haynesworth, S.E.4    Ringden, O.5
  • 132
    • 0242300602 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytes or natural killer cells
    • Rasmusson I, Ringden O, Sundberg B, Le Blanc K. Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytes or natural killer cells. Transplantation 2003; 76: 1208-1213.
    • (2003) Transplantation , vol.76 , pp. 1208-1213
    • Rasmusson, I.1    Ringden, O.2    Sundberg, B.3    Le Blanc, K.4
  • 133
    • 0037442264 scopus 로고    scopus 로고
    • Suppression of allogeneic T-cell proliferation by human marrow stromal cells: Implications in transplantation
    • Tse WT, Pendleton JD, Beyer WM, Egalka MC, Guinan EC. Suppression of allogeneic T-cell proliferation by human marrow stromal cells: implications in transplantation. Transplantation 2003; 75: 389-397.
    • (2003) Transplantation , vol.75 , pp. 389-397
    • Tse, W.T.1    Pendleton, J.D.2    Beyer, W.M.3    Egalka, M.C.4    Guinan, E.C.5
  • 134
    • 22144473736 scopus 로고    scopus 로고
    • Human mesenchymal stem cells require monocyte-mediated activation to suppress alloreactive T cells
    • Groh ME, Maitra B, Szekely E, Koc ON. Human mesenchymal stem cells require monocyte-mediated activation to suppress alloreactive T cells. Exp Hematol 2005; 33: 928-934.
    • (2005) Exp Hematol , vol.33 , pp. 928-934
    • Groh, M.E.1    Maitra, B.2    Szekely, E.3    Koc, O.N.4
  • 135
    • 14944339174 scopus 로고    scopus 로고
    • Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsiveness
    • Beyth S, Borovsky Z, Mevorach D, et al. Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsiveness. Blood 2005; 105: 2214-2219.
    • (2005) Blood , vol.105 , pp. 2214-2219
    • Beyth, S.1    Borovsky, Z.2    Mevorach, D.3
  • 136
    • 13544249606 scopus 로고    scopus 로고
    • Human mesenchymal stem cells modulate allogeneic immune cell responses
    • Aggarwal S, Pittenger MF. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood 2005; 105: 1815-1822.
    • (2005) Blood , vol.105 , pp. 1815-1822
    • Aggarwal, S.1    Pittenger, M.F.2
  • 137
    • 33746889097 scopus 로고    scopus 로고
    • Role for interferon-gamma in the immunomodulatory activity of human bone marrow mesenchymal stem cells
    • Krampera M, Cosmi L, Angeli R, et al. Role for interferon-gamma in the immunomodulatory activity of human bone marrow mesenchymal stem cells. Stem Cells 2006; 24: 386-398.
    • (2006) Stem Cells , vol.24 , pp. 386-398
    • Krampera, M.1    Cosmi, L.2    Angeli, R.3
  • 138
    • 2942595706 scopus 로고    scopus 로고
    • Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation
    • Meisel R, Zibert A, Laryea M, Gobel U, Daubener W, Dilloo D. Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation. Blood 2004; 103: 4619-4621.
    • (2004) Blood , vol.103 , pp. 4619-4621
    • Meisel, R.1    Zibert, A.2    Laryea, M.3    Gobel, U.4    Daubener, W.5    Dilloo, D.6
  • 139
    • 33846006154 scopus 로고    scopus 로고
    • Nitric oxide plays a critical role in suppression of T-cell proliferation by mesenchymal stem cells
    • Sato K, Ozaki K, Oh I, et al. Nitric oxide plays a critical role in suppression of T-cell proliferation by mesenchymal stem cells. Blood 2007; 109: 228-234.
    • (2007) Blood , vol.109 , pp. 228-234
    • Sato, K.1    Ozaki, K.2    Oh, I.3
  • 140
    • 84872498240 scopus 로고    scopus 로고
    • Notch1 modulates mesenchymal stem cells mediated regulatory T-cell induction
    • Del Papa B, Sportoletti P, Cecchini D, et al. Notch1 modulates mesenchymal stem cells mediated regulatory T-cell induction. Eur J Immunol 2013; 43: 182-187.
    • (2013) Eur J Immunol , vol.43 , pp. 182-187
    • Del Papa, B.1    Sportoletti, P.2    Cecchini, D.3
  • 141
    • 38949175025 scopus 로고    scopus 로고
    • Mesenchymal cells recruit and regulate T regulatory cells
    • Di Ianni M, Del Papa B, De Ioanni M, et al. Mesenchymal cells recruit and regulate T regulatory cells. Exp Hematol 2008; 36: 309-318.
    • (2008) Exp Hematol , vol.36 , pp. 309-318
    • Di Ianni, M.1    Del Papa, B.2    de Ioanni, M.3
  • 142
    • 17844391825 scopus 로고    scopus 로고
    • Interaction of human mesenchymal stem cells with cells involved in alloantigen-specific immune response favors the differentiation of CD4+ T-cell subsets expressing a regulatory/suppressive phenotype
    • Maccario R, Podesta M, Moretta A, et al. Interaction of human mesenchymal stem cells with cells involved in alloantigen-specific immune response favors the differentiation of CD4+ T-cell subsets expressing a regulatory/suppressive phenotype. Haematologica 2005; 90: 516-525.
    • (2005) Haematologica , vol.90 , pp. 516-525
    • Maccario, R.1    Podesta, M.2    Moretta, A.3
  • 143
    • 78650827566 scopus 로고    scopus 로고
    • Regulatory T-cell generation and kidney allograft tolerance induced by mesenchymal stem cells associated with indoleamine 2,3-dioxygenase expression
    • Ge W, Jiang J, Arp J, Liu W, Garcia B, Wang H. Regulatory T-cell generation and kidney allograft tolerance induced by mesenchymal stem cells associated with indoleamine 2,3-dioxygenase expression. Transplantation 2010; 90: 1312-1320.
    • (2010) Transplantation , vol.90 , pp. 1312-1320
    • Ge, W.1    Jiang, J.2    Arp, J.3    Liu, W.4    Garcia, B.5    Wang, H.6
  • 144
    • 67349224622 scopus 로고    scopus 로고
    • Mesenchymal stem cells protect NOD mice from diabetes by inducing regulatory T cells
    • Madec AM, Mallone R, Afonso G, et al. Mesenchymal stem cells protect NOD mice from diabetes by inducing regulatory T cells. Diabetologia 2009; 52: 1391-1399.
    • (2009) Diabetologia , vol.52 , pp. 1391-1399
    • Madec, A.M.1    Mallone, R.2    Afonso, G.3
  • 145
    • 61849123247 scopus 로고    scopus 로고
    • Cell contact, prostaglandin E(2) and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4+CD25(High) forkhead box P3+ regulatory T cells
    • English K, Ryan JM, Tobin L, Murphy MJ, Barry FP, Mahon BP. Cell contact, prostaglandin E(2) and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4+CD25(High) forkhead box P3+ regulatory T cells. Clin Exp Immunol 2009; 156: 149-160.
    • (2009) Clin Exp Immunol , vol.156 , pp. 149-160
    • English, K.1    Ryan, J.M.2    Tobin, L.3    Murphy, M.J.4    Barry, F.P.5    Mahon, B.P.6
  • 146
    • 65249161683 scopus 로고    scopus 로고
    • Treatment of experimental arthritis by inducing immune tolerance with human adipose-derived mesenchymal stem cells
    • Gonzalez MA, Gonzalez-Rey E, Rico L, Buscher D, Delgado M. Treatment of experimental arthritis by inducing immune tolerance with human adipose-derived mesenchymal stem cells. Arthritis Rheum 2009; 60: 1006-1019.
    • (2009) Arthritis Rheum , vol.60 , pp. 1006-1019
    • Gonzalez, M.A.1    Gonzalez-Rey, E.2    Rico, L.3    Buscher, D.4    Delgado, M.5
  • 147
    • 73449133395 scopus 로고    scopus 로고
    • Human adipose-derived mesenchymal stem cells reduce inflammatory and T cell responses and induce regulatory T cells in vitro in rheumatoid arthritis
    • Gonzalez-Rey E, Gonzalez MA, Varela N, et al. Human adipose-derived mesenchymal stem cells reduce inflammatory and T cell responses and induce regulatory T cells in vitro in rheumatoid arthritis. Ann Rheum Dis 2010; 69: 241-248.
    • (2010) Ann Rheum Dis , vol.69 , pp. 241-248
    • Gonzalez-Rey, E.1    Gonzalez, M.A.2    Varela, N.3
  • 148
    • 84881345199 scopus 로고    scopus 로고
    • Treatment of foot disease in patients with type 2 diabetes mellitus using human umbilical cord blood mesenchymal stem cells: Response and correction of immunological anomalies
    • Li X Y, Zheng ZH, Li XY, et al. Treatment of foot disease in patients with type 2 diabetes mellitus using human umbilical cord blood mesenchymal stem cells: response and correction of immunological anomalies. Curr Pharm Des 2013; 19: 4893-4899.
    • (2013) Curr Pharm Des , vol.19 , pp. 4893-4899
    • Li, X.Y.1    Zheng, Z.H.2    Li, X.Y.3
  • 149
    • 34147126415 scopus 로고    scopus 로고
    • Mesenchymal stem cells effectively modulate pathogenic immune response in experimental autoimmune encephalomyelitis
    • Gerdoni E, Gallo B, Casazza S, et al. Mesenchymal stem cells effectively modulate pathogenic immune response in experimental autoimmune encephalomyelitis. Ann Neurol 2007; 61: 219-227.
    • (2007) Ann Neurol , vol.61 , pp. 219-227
    • Gerdoni, E.1    Gallo, B.2    Casazza, S.3
  • 150
    • 64249129065 scopus 로고    scopus 로고
    • Mesenchymal stem cells suppress B-cell terminal differentiation
    • Asari S, Itakura S, Ferreri K, et al. Mesenchymal stem cells suppress B-cell terminal differentiation. Exp Hematol 2009; 37: 604-615.
    • (2009) Exp Hematol , vol.37 , pp. 604-615
    • Asari, S.1    Itakura, S.2    Ferreri, K.3
  • 151
    • 18844404360 scopus 로고    scopus 로고
    • Bone marrow mesenchymal progenitor cells inhibit lymphocyte proliferation by activation of the programmed death 1 pathway
    • Augello A, Tasso R, Negrini SM, et al. Bone marrow mesenchymal progenitor cells inhibit lymphocyte proliferation by activation of the programmed death 1 pathway. Eur J Immunol 2005; 35: 1482-1490.
    • (2005) Eur J Immunol , vol.35 , pp. 1482-1490
    • Augello, A.1    Tasso, R.2    Negrini, S.M.3
  • 152
    • 33947593728 scopus 로고    scopus 로고
    • Mesenchymal stem cells stimulate antibody secretion in human B cells
    • Rasmusson I, Le Blanc K, Sundberg B, Ringden O. Mesenchymal stem cells stimulate antibody secretion in human B cells. Scand J Immunol 2007; 65: 336-343.
    • (2007) Scand J Immunol , vol.65 , pp. 336-343
    • Rasmusson, I.1    Le Blanc, K.2    Sundberg, B.3    Ringden, O.4
  • 153
    • 40949119840 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells induce both polyclonal expansion and differentiation of B cells isolated from healthy donors and systemic lupus erythematosus patients
    • Traggiai E, Volpi S, Schena F, et al. Bone marrow-derived mesenchymal stem cells induce both polyclonal expansion and differentiation of B cells isolated from healthy donors and systemic lupus erythematosus patients. Stem Cells 2008; 26: 562-569.
    • (2008) Stem Cells , vol.26 , pp. 562-569
    • Traggiai, E.1    Volpi, S.2    Schena, F.3
  • 154
    • 80052681525 scopus 로고    scopus 로고
    • Potential role of NK cells in the pathogenesis of inflammatory bowel disease
    • 2011
    • Yadav PK, Chen C, Liu Z. Potential role of NK cells in the pathogenesis of inflammatory bowel disease. J Biomed Biotechnol 2011; 2011: 348530.
    • (2011) J Biomed Biotechnol , pp. 348530
    • Yadav, P.K.1    Chen, C.2    Liu, Z.3
  • 155
    • 84865473435 scopus 로고    scopus 로고
    • Technical advance: Decreased helper T cells and increased natural killer cells in chronic periodontitis analyzed by a novel method for isolating resident lymphocytes
    • Muthukuru M. Technical advance: decreased helper T cells and increased natural killer cells in chronic periodontitis analyzed by a novel method for isolating resident lymphocytes. J Leukoc Biol 2012; 92: 683-692.
    • (2012) J Leukoc Biol , vol.92 , pp. 683-692
    • Muthukuru, M.1
  • 157
    • 18544371666 scopus 로고    scopus 로고
    • Human mesenchymal stem cells inhibit differentiation and function of monocyte-derived dendritic cells
    • Jiang XX, Zhang Y, Liu B, et al. Human mesenchymal stem cells inhibit differentiation and function of monocyte-derived dendritic cells. Blood 2005; 105: 4120-4126.
    • (2005) Blood , vol.105 , pp. 4120-4126
    • Jiang, X.X.1    Zhang, Y.2    Liu, B.3
  • 158
    • 2942562525 scopus 로고    scopus 로고
    • Effects of mesenchymal stem cells on differentiation, maturation, and function of human monocyte-derived dendritic cells
    • Zhang W, Ge W, Li C, et al. Effects of mesenchymal stem cells on differentiation, maturation, and function of human monocyte-derived dendritic cells. Stem Cells Dev 2004; 13: 263-271.
    • (2004) Stem Cells Dev , vol.13 , pp. 263-271
    • Zhang, W.1    Ge, W.2    Li, C.3
  • 159
    • 33846220680 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit dendritic cell differentiation and function by preventing entry into the cell cycle
    • Ramasamy R, Fazekasova H, Lam EW, Soeiro I, Lombardi G, Dazzi F. Mesenchymal stem cells inhibit dendritic cell differentiation and function by preventing entry into the cell cycle. Transplantation 2007; 83: 71-76.
    • (2007) Transplantation , vol.83 , pp. 71-76
    • Ramasamy, R.1    Fazekasova, H.2    Lam, E.W.3    Soeiro, I.4    Lombardi, G.5    Dazzi, F.6
  • 160
    • 69249227552 scopus 로고    scopus 로고
    • 2
    • Spaggiari GM, Abdelrazik H, Becchetti F, Moretta L. MSCs inhibit monocyte-derived DC maturation and function by selectively interfering with the generation of immature DCs: central role of MSC-derived prostaglandin E2. Blood 2009; 113: 6576-6583.
    • (2009) Blood , vol.113 , pp. 6576-6583
    • Spaggiari, G.M.1    Abdelrazik, H.2    Becchetti, F.3    Moretta, L.4
  • 161
    • 58149326737 scopus 로고    scopus 로고
    • 2-dependent reprogramming of host macrophages to increase their interleukin-10 production
    • Nemeth K, Leelahavanichkul A, Yuen PS, et al. Bone marrow stromal cells attenuate sepsis via prostaglandin E2-dependent reprogramming of host macrophages to increase their interleukin-10 production. Nat Med 2009; 15: 42-49.
    • (2009) Nat Med , vol.15 , pp. 42-49
    • Nemeth, K.1    Leelahavanichkul, A.2    Yuen, P.S.3
  • 162
    • 78149335954 scopus 로고    scopus 로고
    • Human gingiva-derived mesenchymal stem cells elicit polarization of m2 macrophages and enhance cutaneous wound healing
    • Zhang QZ, Su WR, Shi SH, et al. Human gingiva-derived mesenchymal stem cells elicit polarization of m2 macrophages and enhance cutaneous wound healing. Stem Cells 2010; 28: 1856-1868.
    • (2010) Stem Cells , vol.28 , pp. 1856-1868
    • Zhang, Q.Z.1    Su, W.R.2    Shi, S.H.3
  • 163
    • 77949264274 scopus 로고    scopus 로고
    • Human gingiva-derived mesenchymal stem cells are superior to bone marrow-derived mesenchymal stem cells for cell therapy in regenerative medicine
    • Tomar GB, Srivastava RK, Gupta N, et al. Human gingiva-derived mesenchymal stem cells are superior to bone marrow-derived mesenchymal stem cells for cell therapy in regenerative medicine. Biochem Biophys Res Commun 2010; 393: 377-383.
    • (2010) Biochem Biophys Res Commun , vol.393 , pp. 377-383
    • Tomar, G.B.1    Srivastava, R.K.2    Gupta, N.3
  • 164
    • 84866522872 scopus 로고    scopus 로고
    • Fas ligand regulates the immunomodulatory properties of dental pulp stem cells
    • Zhao Y, Wang L, Jin Y, Shi S. Fas ligand regulates the immunomodulatory properties of dental pulp stem cells. J Dent Res 2012; 91: 948-954.
    • (2012) J Dent Res , vol.91 , pp. 948-954
    • Zhao, Y.1    Wang, L.2    Jin, Y.3    Shi, S.4
  • 165
    • 38148999409 scopus 로고    scopus 로고
    • Characterization of the apical papilla and its residing stem cells from human immature permanent teeth: A pilot study
    • Sonoyama W, Liu Y, Yamaza T, et al. Characterization of the apical papilla and its residing stem cells from human immature permanent teeth: a pilot study. J Endod 2008; 34: 166-171.
    • (2008) J Endod , vol.34 , pp. 166-171
    • Sonoyama, W.1    Liu, Y.2    Yamaza, T.3
  • 166
    • 64549091514 scopus 로고    scopus 로고
    • Immunomodulatory properties of human periodontal ligament stem cells
    • Wada N, Menicanin D, Shi S, Bartold PM, Gronthos S. Immunomodulatory properties of human periodontal ligament stem cells. J Cell Physiol 2009; 219: 667-676.
    • (2009) J Cell Physiol , vol.219 , pp. 667-676
    • Wada, N.1    Menicanin, D.2    Shi, S.3    Bartold, P.M.4    Gronthos, S.5
  • 167
    • 5444262511 scopus 로고    scopus 로고
    • Toll-like receptor control of the adaptive immune responses
    • Iwasaki A, Medzhitov R. Toll-like receptor control of the adaptive immune responses. Nat Immunol 2004; 5: 987-995.
    • (2004) Nat Immunol , vol.5 , pp. 987-995
    • Iwasaki, A.1    Medzhitov, R.2
  • 168
    • 84859769099 scopus 로고    scopus 로고
    • Immunomodulatory effect of canine periodontal ligament stem cells on allogenic and xenogenic peripheral blood mononuclear cells
    • Kim HS, Kim KH, Kim SH, et al. Immunomodulatory effect of canine periodontal ligament stem cells on allogenic and xenogenic peripheral blood mononuclear cells. J Periodontal Implant Sci 2010; 40: 265-270.
    • (2010) J Periodontal Implant Sci , vol.40 , pp. 265-270
    • Kim, H.S.1    Kim, K.H.2    Kim, S.H.3
  • 169
    • 78149317968 scopus 로고    scopus 로고
    • Allogeneic periodontal ligament stem cell therapy for periodontitis in swine
    • Ding G, Liu Y, Wang W, et al. Allogeneic periodontal ligament stem cell therapy for periodontitis in swine. Stem Cells 2010; 28: 1829-1838.
    • (2010) Stem Cells , vol.28 , pp. 1829-1838
    • Ding, G.1    Liu, Y.2    Wang, W.3
  • 170
    • 84869506142 scopus 로고    scopus 로고
    • Mesenchymal stem cells derived from inflamed periodontal ligaments exhibit impaired immunomodulation
    • Liu D, Xu J, Liu O, et al. Mesenchymal stem cells derived from inflamed periodontal ligaments exhibit impaired immunomodulation. J Clin Periodontol 2012; 39: 1174-1182.
    • (2012) J Clin Periodontol , vol.39 , pp. 1174-1182
    • Liu, D.1    Xu, J.2    Liu, O.3
  • 171
    • 79251577049 scopus 로고    scopus 로고
    • Immunomodulatory properties of stem cells from human exfoliated deciduous teeth
    • Yamaza T, Kentaro A, Chen C, et al. Immunomodulatory properties of stem cells from human exfoliated deciduous teeth. Stem Cell Res Ther 2010; 1: 5.
    • (2010) Stem Cell Res Ther , vol.1 , pp. 5
    • Yamaza, T.1    Kentaro, A.2    Chen, C.3
  • 172
    • 76249084930 scopus 로고    scopus 로고
    • Mesenchymal stem cells derived from human gingiva are capable of immunomodulatory functions and ameliorate inflammation-related tissue destruction in experimental colitis
    • Zhang Q, Shi S, Liu Y, Uyanne J, Shi Y, Le AD. Mesenchymal stem cells derived from human gingiva are capable of immunomodulatory functions and ameliorate inflammation-related tissue destruction in experimental colitis. J Immunol 2009; 183: 7787-7798.
    • (2009) J Immunol , vol.183 , pp. 7787-7798
    • Zhang, Q.1    Shi, S.2    Liu, Y.3    Uyanne, J.4    Shi, Y.5    Le, A.D.6
  • 173
    • 78649386082 scopus 로고    scopus 로고
    • Genetic engineering of mesenchymal stem cells and its application in human disease therapy
    • Hodgkinson CP, Gomez JA, Mirotsou M, Dzau VJ. Genetic engineering of mesenchymal stem cells and its application in human disease therapy. Hum Gene Ther 2010; 21: 1513-1526.
    • (2010) Hum Gene Ther , vol.21 , pp. 1513-1526
    • Hodgkinson, C.P.1    Gomez, J.A.2    Mirotsou, M.3    Dzau, V.J.4
  • 174
    • 84899086867 scopus 로고    scopus 로고
    • Prevention of actute allograft rejection in an orthotopic liver transplant model in rats by interleukin-10 engineered mesenchymal stem cells
    • Niu J, Yue W, Song Y, et al. Prevention of actute allograft rejection in an orthotopic liver transplant model in rats by interleukin-10 engineered mesenchymal stem cells. Clin Exp Immunol 2014; 176: 473-484.
    • (2014) Clin Exp Immunol , vol.176 , pp. 473-484
    • Niu, J.1    Yue, W.2    Song, Y.3
  • 175
    • 84885111559 scopus 로고    scopus 로고
    • mRNA-engineered mesenchymal stem cells for targeted delivery of interleukin-10 to sites of inflammation
    • Levy O, Zhao W, Mortensen LJ, et al. mRNA-engineered mesenchymal stem cells for targeted delivery of interleukin-10 to sites of inflammation. Blood 2013; 122: e23-e32.
    • (2013) Blood , vol.122
    • Levy, O.1    Zhao, W.2    Mortensen, L.J.3
  • 176
    • 77954982590 scopus 로고    scopus 로고
    • Interleukin-10 delivery via mesenchymal stem cells: A novel gene therapy approach to prevent lung ischemia-reperfusion injury
    • Manning E, Pham S, Li S, et al. Interleukin-10 delivery via mesenchymal stem cells: a novel gene therapy approach to prevent lung ischemia-reperfusion injury. Hum Gene Ther 2010; 21: 713-727.
    • (2010) Hum Gene Ther , vol.21 , pp. 713-727
    • Manning, E.1    Pham, S.2    Li, S.3
  • 177
    • 84856498765 scopus 로고    scopus 로고
    • Current status and future development of cell transplantation therapy for periodontal tissue regeneration
    • Yoshida T, Washio K, Iwata T, Okano T, Ishikawa I. Current status and future development of cell transplantation therapy for periodontal tissue regeneration. Int J Dent 2012; 2012: 307024.
    • (2012) Int J Dent 2012 , pp. 307024
    • Yoshida, T.1    Washio, K.2    Iwata, T.3    Okano, T.4    Ishikawa, I.5
  • 178
    • 7044263352 scopus 로고    scopus 로고
    • Enhancement of periodontal tissue regeneration by transplantation of bone marrow mesenchymal stem cells
    • Kawaguchi H, Hirachi A, Hasegawa N, et al. Enhancement of periodontal tissue regeneration by transplantation of bone marrow mesenchymal stem cells. J Periodontol 2004; 75: 1281-1287.
    • (2004) J Periodontol , vol.75 , pp. 1281-1287
    • Kawaguchi, H.1    Hirachi, A.2    Hasegawa, N.3
  • 179
    • 33747136697 scopus 로고    scopus 로고
    • A novel approach to periodontal tissue regeneration with mesenchymal stem cells and platelet-rich plasma using tissue engineering technology: A clinical case report
    • Yamada Y, Ueda M, Hibi H, Baba S. A novel approach to periodontal tissue regeneration with mesenchymal stem cells and platelet-rich plasma using tissue engineering technology: a clinical case report. Int J Periodontics Restorative Dent 2006; 26: 363-369.
    • (2006) Int J Periodontics Restorative Dent , vol.26 , pp. 363-369
    • Yamada, Y.1    Ueda, M.2    Hibi, H.3    Baba, S.4
  • 180
    • 52049116158 scopus 로고    scopus 로고
    • Metabolic and functional characterization of human adipose-derived stem cells in tissue engineering
    • Mischen BT, Follmar KE, Moyer KE, et al. Metabolic and functional characterization of human adipose-derived stem cells in tissue engineering. Plast Reconstr Surg 2008; 122: 725-738.
    • (2008) Plast Reconstr Surg , vol.122 , pp. 725-738
    • Mischen, B.T.1    Follmar, K.E.2    Moyer, K.E.3
  • 181
    • 52649147066 scopus 로고    scopus 로고
    • Adipose-derived stem cell: A better stem cell than BMSC
    • Zhu Y, Liu T, Song K, Fan X, Ma X, Cui Z. Adipose-derived stem cell: a better stem cell than BMSC. Cell Biochem Funct 2008; 26: 664-675.
    • (2008) Cell Biochem Funct , vol.26 , pp. 664-675
    • Zhu, Y.1    Liu, T.2    Song, K.3    Fan, X.4    Ma, X.5    Cui, Z.6
  • 182
    • 0035067539 scopus 로고    scopus 로고
    • Multilineage cells from human adipose tissue: Implications for cell-based therapies
    • Zuk PA, Zhu M, Mizuno H, et al. Multilineage cells from human adipose tissue: implications for cell-based therapies. Tissue Eng 2001; 7: 211-228.
    • (2001) Tissue Eng , vol.7 , pp. 211-228
    • Zuk, P.A.1    Zhu, M.2    Mizuno, H.3
  • 184
    • 49249088145 scopus 로고    scopus 로고
    • Periodontal ligament stem cell-mediated treatment for periodontitis in miniature swine
    • Liu Y, Zheng Y, Ding G, et al. Periodontal ligament stem cell-mediated treatment for periodontitis in miniature swine. Stem Cells 2008; 26: 1065-1073.
    • (2008) Stem Cells , vol.26 , pp. 1065-1073
    • Liu, Y.1    Zheng, Y.2    Ding, G.3
  • 185
    • 73649097540 scopus 로고    scopus 로고
    • Utility of PDL progenitors for in vivo tissue regeneration: A report of 3 cases
    • Feng F, Akiyama K, Liu Y, et al. Utility of PDL progenitors for in vivo tissue regeneration: a report of 3 cases. Oral Dis 2010; 16: 20-28.
    • (2010) Oral Dis , vol.16 , pp. 20-28
    • Feng, F.1    Akiyama, K.2    Liu, Y.3
  • 186
    • 18244393188 scopus 로고    scopus 로고
    • Human periodontal ligament cell sheets can regenerate periodontal ligament tissue in an athymic rat model
    • Hasegawa M, Yamato M, Kikuchi A, Okano T, Ishikawa I. Human periodontal ligament cell sheets can regenerate periodontal ligament tissue in an athymic rat model. Tissue Eng 2005; 11: 469-478.
    • (2005) Tissue Eng , vol.11 , pp. 469-478
    • Hasegawa, M.1    Yamato, M.2    Kikuchi, A.3    Okano, T.4    Ishikawa, I.5
  • 187
    • 34347358566 scopus 로고    scopus 로고
    • Highly efficient neural differentiation of human somatic stem cells, isolated by minimally invasive periodontal surgery
    • Widera D, Grimm WD, Moebius JM, et al. Highly efficient neural differentiation of human somatic stem cells, isolated by minimally invasive periodontal surgery. Stem Cells Dev 2007; 16: 447-460.
    • (2007) Stem Cells Dev , vol.16 , pp. 447-460
    • Widera, D.1    Grimm, W.D.2    Moebius, J.M.3
  • 188
    • 84861133865 scopus 로고    scopus 로고
    • The ability of human periodontium-derived stem cells to regenerate periodontal tissues: A preliminary in vivo investigation
    • Grimm WD, Dannan A, Becher S, et al. The ability of human periodontium-derived stem cells to regenerate periodontal tissues: a preliminary in vivo investigation. Int J Periodontics Restorative Dent 2011; 31: e94-e101.
    • (2011) Int J Periodontics Restorative Dent , vol.31
    • Grimm, W.D.1    Dannan, A.2    Becher, S.3
  • 191
    • 76749091376 scopus 로고    scopus 로고
    • The healing of critical-sized femoral segmental bone defects in rabbits using baculovirus-engineered mesenchymal stem cells
    • Lin C Y, Chang YH, Lin KJ, et al. The healing of critical-sized femoral segmental bone defects in rabbits using baculovirus-engineered mesenchymal stem cells. Biomaterials 2010; 31: 3222-3230.
    • (2010) Biomaterials , vol.31 , pp. 3222-3230
    • Lin, C.Y.1    Chang, Y.H.2    Lin, K.J.3
  • 192
    • 84902455016 scopus 로고    scopus 로고
    • Characterization of the enhanced bone regenerative capacity of human periodontal ligament stem cells engineered to express the gene encoding bone morphogenetic protein 2
    • Mar 25, doi: 10.1089/ten.TEA.2013.0648
    • Jung IH, Lee SH, Jun CM, Oh N, Yun JH. Characterization of the enhanced bone regenerative capacity of human periodontal ligament stem cells engineered to express the gene encoding bone morphogenetic protein 2. Tissue Eng Part A 2014, Mar 25. doi: 10.1089/ten.TEA.2013.0648
    • (2014) Tissue Eng Part A
    • Jung, I.H.1    Lee, S.H.2    Jun, C.M.3    Oh, N.4    Yun, J.H.5
  • 193
    • 79954417016 scopus 로고    scopus 로고
    • Mandibular alveolar bony defect repair using bone morphogenetic protein 2-expressing autologous mesenchymal stem cells
    • Chung VH, Chen AY, Kwan CC, Chen PK, Chang SC. Mandibular alveolar bony defect repair using bone morphogenetic protein 2-expressing autologous mesenchymal stem cells. J Craniofac Surg 2011; 22: 450-454.
    • (2011) J Craniofac Surg , vol.22 , pp. 450-454
    • Chung, V.H.1    Chen, A.Y.2    Kwan, C.C.3    Chen, P.K.4    Chang, S.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.