Mitoxantrone ability to induce premature senescence in human dental pulp stem cells and human dermal fibroblasts

Journal of Physiology and Pharmacology

Volumn 64, Issue 2, 2013, Pages

  Seifrtova, M ^a   Havelek, R ^a,b   Soukup, T ^a   Filipova, A ^a   Mokry, J ^a   Rezacova, M ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

^b UNIVERSITY OF PARDUBICE   (Czech Republic)

Author keywords

Apoptosis; Dental pulp stem cells; Dermal fibroblasts; Mitoxantrone; Stress induced premature senescence

Indexed keywords

BETA GALACTOSIDASE; CASPASE; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 2A; HISTONE H2AX; MITOXANTRONE; PROTEIN P53; ANTINEOPLASTIC AGENT; GYRASE INHIBITOR;

APOPTOSIS; ARTICLE; CELL CYCLE; CELL PROLIFERATION; CELL STRUCTURE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; ENZYME ACTIVITY; FIBROBLAST; FLOW CYTOMETRY; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; SENESCENCE; STEM CELL; TOOTH PULP; WESTERN BLOTTING; CELL CULTURE; CELL SURVIVAL; CYTOLOGY; DNA DAMAGE; DRUG EFFECTS; MALE; METABOLISM; SKIN;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASES; CELL CYCLE; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; DENTAL PULP; DNA DAMAGE; FIBROBLASTS; HUMANS; MALE; MITOXANTRONE; SKIN; STEM CELLS; TOPOISOMERASE II INHIBITORS;

EID: 84891721700     PISSN: 08675910     EISSN: 18991505     Source Type: Journal    
DOI: None     Document Type: Article

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