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Volumn 24, Issue 2, 2006, Pages 386-398

Role for interferon-γ in the immunomodulatory activity of human bone marrow mesenchymal stem cells

Author keywords

Immune suppression; Indoleamine 2,3 dioxygenase; Mesenchymal stem cells

Indexed keywords

GAMMA INTERFERON; CD4 ANTIGEN; CD8 ANTIGEN; IMMUNOLOGIC FACTOR; INDOLEAMINE 2,3 DIOXYGENASE; INTERLEUKIN 2 RECEPTOR;

EID: 33746889097     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2005-0008     Document Type: Article
Times cited : (1147)

References (51)
  • 1
    • 0020334624 scopus 로고
    • Stromal bone marrow cells and the hematopoietic microenvironment
    • Fridenshtein A. Stromal bone marrow cells and the hematopoietic microenvironment. Arkh Patol 1982;44:3-11.
    • (1982) Arkh Patol , vol.44 , pp. 3-11
    • Fridenshtein, A.1
  • 2
    • 0033515827 scopus 로고    scopus 로고
    • Multilineage potential of adult human mesenchymal stem cells
    • Pittenger MF, Mackay AM, Beck SC et al. Multilineage potential of adult human mesenchymal stem cells. Science 1999;284:143-147.
    • (1999) Science , vol.284 , pp. 143-147
    • Pittenger, M.F.1    Mackay, A.M.2    Beck, S.C.3
  • 3
  • 4
    • 0028788268 scopus 로고
    • Myogenic cells derived from rat bone marrow mesenchymal stem cells exposed to 5-azacytidine
    • Wakitani S, Saito T, Caplan AI. Myogenic cells derived from rat bone marrow mesenchymal stem cells exposed to 5-azacytidine. Muscle Nerve 1995;18:1417-1426.
    • (1995) Muscle Nerve , vol.18 , pp. 1417-1426
    • Wakitani, S.1    Saito, T.2    Caplan, A.I.3
  • 5
    • 0034663515 scopus 로고    scopus 로고
    • Adult rat and human bone marrow stromal cells differentiate into neurons
    • Woodbury D, Schwarz EJ, Prockop DJ et al. Adult rat and human bone marrow stromal cells differentiate into neurons. J Neurosci Res 2000;61:364-370.
    • (2000) J Neurosci Res , vol.61 , pp. 364-370
    • Woodbury, D.1    Schwarz, E.J.2    Prockop, D.J.3
  • 6
    • 0035525779 scopus 로고    scopus 로고
    • Purification and ex vivo expansion of postnatal human marrow mesodermal progenitor cells
    • Reyes M, Lund T, Lenvik T et al. Purification and ex vivo expansion of postnatal human marrow mesodermal progenitor cells. Blood 2001;98:2615-2625.
    • (2001) Blood , vol.98 , pp. 2615-2625
    • Reyes, M.1    Lund, T.2    Lenvik, T.3
  • 7
    • 0033524834 scopus 로고    scopus 로고
    • Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4
    • Peled A, Petit I, Kollet O et al. Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4. Science 1999;283:845-848.
    • (1999) Science , vol.283 , pp. 845-848
    • Peled, A.1    Petit, I.2    Kollet, O.3
  • 8
    • 0033977382 scopus 로고    scopus 로고
    • Rapid hematopoietic recovery after coinfusion of autologous-blood stem cells and culture-expanded marrow mesenchymal stem cells in advanced breast cancer patients receiving high-dose chemotherapy
    • Koc ON, Gerson SL, Cooper BW et al. Rapid hematopoietic recovery after coinfusion of autologous-blood stem cells and culture-expanded marrow mesenchymal stem cells in advanced breast cancer patients receiving high-dose chemotherapy. J Clin Oncol 2000;18:307-316.
    • (2000) J Clin Oncol , vol.18 , pp. 307-316
    • Koc, O.N.1    Gerson, S.L.2    Cooper, B.W.3
  • 9
    • 0029000896 scopus 로고
    • Cultured adherent cells from marrow can serve as long-lasting precursor cells for bone, cartilage, and lung in irradiated mice
    • Pereira RF, Halford KW, O'Hara MD et al. Cultured adherent cells from marrow can serve as long-lasting precursor cells for bone, cartilage, and lung in irradiated mice. Proc Natl Acad Sci U S A 1995;92:4857-4861.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 4857-4861
    • Pereira, R.F.1    Halford, K.W.2    O'Hara, M.D.3
  • 10
    • 0035525249 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Stealth and suppression
    • Devine SM, Peter S, Martin BJ et al. Mesenchymal stem cells: Stealth and suppression. Cancer J (suppl 2) S76-S82, 2001.
    • (2001) Cancer J , Issue.2 SUPPL.
    • Devine, S.M.1    Peter, S.2    Martin, B.J.3
  • 11
    • 0036142213 scopus 로고    scopus 로고
    • Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart
    • Toma C, Pittenger MF, Cahill KS et al. Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart. Circulation 2002;105:93-98.
    • (2002) Circulation , vol.105 , pp. 93-98
    • Toma, C.1    Pittenger, M.F.2    Cahill, K.S.3
  • 12
    • 0032489651 scopus 로고    scopus 로고
    • Muscle regeneration by bone marrow-derived myogenic progenitors
    • Ferrari G, Cusella-De Angelis G, Coletta M et al. Muscle regeneration by bone marrow-derived myogenic progenitors. Science 1998;279:1528-1530.
    • (1998) Science , vol.279 , pp. 1528-1530
    • Ferrari, G.1    Cusella-De Angelis, G.2    Coletta, M.3
  • 13
    • 0035810240 scopus 로고    scopus 로고
    • Bone marrow cells regenerate infarcted myocardium
    • Orlic D, Kajstura J, Chimenti S et al. Bone marrow cells regenerate infarcted myocardium. Nature 2001;410:701-705.
    • (2001) Nature , vol.410 , pp. 701-705
    • Orlic, D.1    Kajstura, J.2    Chimenti, S.3
  • 14
    • 0033553591 scopus 로고    scopus 로고
    • Bone marrow as a potential source of hepatic oval cells
    • Petersen BE, Bowen WC, Patrene KD et al. Bone marrow as a potential source of hepatic oval cells. Science 1999;284:1168-1170.
    • (1999) Science , vol.284 , pp. 1168-1170
    • Petersen, B.E.1    Bowen, W.C.2    Patrene, K.D.3
  • 15
    • 0036106054 scopus 로고    scopus 로고
    • Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells
    • Schwartz RE, Reyes M, Koodie L et al. Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells. J Clin Invest 2002;109:1291-1302.
    • (2002) J Clin Invest , vol.109 , pp. 1291-1302
    • Schwartz, R.E.1    Reyes, M.2    Koodie, L.3
  • 16
    • 0034531907 scopus 로고    scopus 로고
    • From marrow to brain: Expression of neuronal phenotypes in adult mice
    • Brazelton TR, Rossi FM, Keshet GI et al. From marrow to brain: Expression of neuronal phenotypes in adult mice. Science 2000;290:1775-1779.
    • (2000) Science , vol.290 , pp. 1775-1779
    • Brazelton, T.R.1    Rossi, F.M.2    Keshet, G.I.3
  • 17
    • 0034532106 scopus 로고    scopus 로고
    • Turning blood into brain: Cells bearing neuronal antigens generated in vivo from bone marrow
    • Mezey E, Chandross KJ, Harta G et al. Turning blood into brain: Cells bearing neuronal antigens generated in vivo from bone marrow. Science 2000;290:1779-1782.
    • (2000) Science , vol.290 , pp. 1779-1782
    • Mezey, E.1    Chandross, K.J.2    Harta, G.3
  • 18
    • 0037019337 scopus 로고    scopus 로고
    • Pluripotency of mesenchymal stem cells derived from adult marrow
    • Jiang Y, Jahagirdar BN, Reinhardt RL et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 2002;418:41-49.
    • (2002) Nature , vol.418 , pp. 41-49
    • Jiang, Y.1    Jahagirdar, B.N.2    Reinhardt, R.L.3
  • 19
    • 0035574556 scopus 로고    scopus 로고
    • Baboon mesenchymal stem cells can be genetically modified to secrete human erythropoietin in vivo
    • Bartholomew A, Patil S, Mackay A et al. Baboon mesenchymal stem cells can be genetically modified to secrete human erythropoietin in vivo. Hum Gene Ther 2001;12:1527-1541.
    • (2001) Hum Gene Ther , vol.12 , pp. 1527-1541
    • Bartholomew, A.1    Patil, S.2    Mackay, A.3
  • 20
    • 0029093553 scopus 로고
    • Extrathymic maturation of alpha beta T cells from hemopoietic stem cells
    • Dejbakhsh-Jones S, Jerabek L, Weissman IL et al. Extrathymic maturation of alpha beta T cells from hemopoietic stem cells. J Immunol 1995;155:3338-3344.
    • (1995) J Immunol , vol.155 , pp. 3338-3344
    • Dejbakhsh-Jones, S.1    Jerabek, L.2    Weissman, I.L.3
  • 21
    • 0029913837 scopus 로고    scopus 로고
    • Selective adhesion of immature thymocytes to bone marrow stromal cells: Relevance to T cell lymphopoiesis
    • Barda-Saad M, Rozenszajn LA, Globerson A et al. Selective adhesion of immature thymocytes to bone marrow stromal cells: relevance to T cell lymphopoiesis. Exp Hematol 1996;24:386-391.
    • (1996) Exp Hematol , vol.24 , pp. 386-391
    • Barda-Saad, M.1    Rozenszajn, L.A.2    Globerson, A.3
  • 22
    • 0033828190 scopus 로고    scopus 로고
    • S. Evidence for migration of donor bone marrow stromal cells into recipient thymus after bone marrow transplantation plus bone grafts: A role of stromal cells in positive selection
    • Li Y, Hisha H, Inaba M et al. S. Evidence for migration of donor bone marrow stromal cells into recipient thymus after bone marrow transplantation plus bone grafts: A role of stromal cells in positive selection. Exp Hematol 2000;28:950-960.
    • (2000) Exp Hematol , vol.28 , pp. 950-960
    • Li, Y.1    Hisha, H.2    Inaba, M.3
  • 23
    • 0034689058 scopus 로고    scopus 로고
    • An essential role for thymic mesenchyme in early T cell development
    • Suniara RK, Jenkinson EJ, Owen JJ. An essential role for thymic mesenchyme in early T cell development. J Exp Med 2000;191:1051-1056.
    • (2000) J Exp Med , vol.191 , pp. 1051-1056
    • Suniara, R.K.1    Jenkinson, E.J.2    Owen, J.J.3
  • 24
    • 0037093058 scopus 로고    scopus 로고
    • Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli
    • Di Nicola M, Carlo-Stella C, Magni M et al. Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. Blood 2002;99:3838-3843.
    • (2002) Blood , vol.99 , pp. 3838-3843
    • Di Nicola, M.1    Carlo-Stella, C.2    Magni, M.3
  • 25
    • 0038204193 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells inhibit the response of naïve and memory antigen-specific T cells to their cognate peptide
    • Krampera M, Glennie S, Laylor R et al. Bone marrow mesenchymal stem cells inhibit the response of naïve and memory antigen-specific T cells to their cognate peptide. Blood 2003;101:3722-3729.
    • (2003) Blood , vol.101 , pp. 3722-3729
    • Krampera, M.1    Glennie, S.2    Laylor, R.3
  • 26
    • 0036142769 scopus 로고    scopus 로고
    • Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo
    • Bartholomew A, Sturgeon C, Siatskas M et al. Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo. Exp Hematol 2002;30:42-48.
    • (2002) Exp Hematol , vol.30 , pp. 42-48
    • Bartholomew, A.1    Sturgeon, C.2    Siatskas, M.3
  • 27
    • 0037115651 scopus 로고    scopus 로고
    • Transplantation of peripheral blood stem cells as compared with bone marrow from HLA-identical siblings in adult patients with acute myeloid leukemia and acute lymphoblastic leukemia
    • Ringden O, Labopin M, Bacigalupo A et al. Transplantation of peripheral blood stem cells as compared with bone marrow from HLA-identical siblings in adult patients with acute myeloid leukemia and acute lymphoblastic leukemia. J Clin Oncol 2002;20:4655-4664.
    • (2002) J Clin Oncol , vol.20 , pp. 4655-4664
    • Ringden, O.1    Labopin, M.2    Bacigalupo, A.3
  • 28
    • 2342482526 scopus 로고    scopus 로고
    • Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells
    • Le Blanc K, Rasmusson I, Sundberg B et al. Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells. Lancet 2004;363:1439-1441.
    • (2004) Lancet , vol.363 , pp. 1439-1441
    • Le Blanc, K.1    Rasmusson, I.2    Sundberg, B.3
  • 29
    • 7044222314 scopus 로고    scopus 로고
    • Acute graft-versus-host disease: Pathophysiology, clinical manifestations, and management
    • Couriel D, Caldera H, Champlin R et al. Acute graft-versus-host disease: Pathophysiology, clinical manifestations, and management. Cancer 2004;101:1936-1946.
    • (2004) Cancer , vol.101 , pp. 1936-1946
    • Couriel, D.1    Caldera, H.2    Champlin, R.3
  • 30
    • 11144354531 scopus 로고    scopus 로고
    • + regulatory thymocytes because of their responsiveness to different cytokines
    • + regulatory thymocytes because of their responsiveness to different cytokines. Blood 2004;103:3117-3121.
    • (2004) Blood , vol.103 , pp. 3117-3121
    • Cosmi, L.1    Liotta, F.2    Angeli, R.3
  • 31
    • 0033784440 scopus 로고    scopus 로고
    • CRTH2 is the most reliable marker for detection of human circulating Th2 and Tc2 cells in health and disease
    • Cosmi L, Annunziato F, Iwasaki M et al. CRTH2 is the most reliable marker for detection of human circulating Th2 and Tc2 cells in health and disease. Eur J Immunol 2000;30:2972-2979.
    • (2000) Eur J Immunol , vol.30 , pp. 2972-2979
    • Cosmi, L.1    Annunziato, F.2    Iwasaki, M.3
  • 33
    • 0032743259 scopus 로고    scopus 로고
    • Annexin V used for measuring apoptosis in the early events of cellular cytotoxicity
    • Aubry JP, Blaecke A, Lecoanet Henchoz S et al. Annexin V used for measuring apoptosis in the early events of cellular cytotoxicity. Cytometry 1999;37:197-204.
    • (1999) Cytometry , vol.37 , pp. 197-204
    • Aubry, J.P.1    Blaecke, A.2    Lecoanet Henchoz, S.3
  • 36
    • 2942595706 scopus 로고    scopus 로고
    • Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase mediated tryptophan degradation
    • Meisel R, Zibert A, Laryea M et al. Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase mediated tryptophan degradation. Blood 2004;103:4619-4621.
    • (2004) Blood , vol.103 , pp. 4619-4621
    • Meisel, R.1    Zibert, A.2    Laryea, M.3
  • 37
    • 0026347919 scopus 로고
    • 1-Methyl-DL-tryptophan, beta-(3-benzofuranyl)-DL-alanine (the oxygen analog of tryptophan), and beta-[3-benzo(b)thienyl]-DL-alanine (the sulfur analog of tryptophan) are competitive inhibitors for indoleamine 2,3-dioxygenase
    • Cady SG, Sono M. 1-Methyl-DL-tryptophan, beta-(3-benzofuranyl)-DL-alanine (the oxygen analog of tryptophan), and beta-[3-benzo(b)thienyl]-DL-alanine (the sulfur analog of tryptophan) are competitive inhibitors for indoleamine 2,3-dioxygenase. Arch Biochem Biophys 1991;291:326-333.
    • (1991) Arch Biochem Biophys , vol.291 , pp. 326-333
    • Cady, S.G.1    Sono, M.2
  • 38
    • 0028917346 scopus 로고
    • Enhancement of 7-nitro indazole-induced inhibition of brain nitric oxide synthase by norharmane
    • Connop BP, Kalisch BE, Boegman RJ et al. Enhancement of 7-nitro indazole-induced inhibition of brain nitric oxide synthase by norharmane. Neurosci Lett 1995;190:69-72.
    • (1995) Neurosci Lett , vol.190 , pp. 69-72
    • Connop, B.P.1    Kalisch, B.E.2    Boegman, R.J.3
  • 39
    • 0042740515 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex
    • Le Blanc K, Tammik L, Sundberg B et al. Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex. Scand J Immunol 2003;57:11-20.
    • (2003) Scand J Immunol , vol.57 , pp. 11-20
    • Le Blanc, K.1    Tammik, L.2    Sundberg, B.3
  • 40
    • 0242300602 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytes or natural killer cells
    • Rasmusson I, Ringden O, Sundberg B et al. Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytes or natural killer cells. Transplantation 2003;76:1208-1213.
    • (2003) Transplantation , vol.76 , pp. 1208-1213
    • Rasmusson, I.1    Ringden, O.2    Sundberg, B.3
  • 41
    • 0742304267 scopus 로고    scopus 로고
    • Immunological properties of human fetal mesenchymal stem cells
    • Gotherstrom C, Ringden O, Tammik C et al. Immunological properties of human fetal mesenchymal stem cells. Am J Obstet Gynecol 2004;190:239-245.
    • (2004) Am J Obstet Gynecol , vol.190 , pp. 239-245
    • Gotherstrom, C.1    Ringden, O.2    Tammik, C.3
  • 42
  • 43
    • 0348223787 scopus 로고    scopus 로고
    • + regulatory T cells by TGF-beta induction of transcription factor Foxp3
    • + regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med 2003;198:1875-1886.
    • (2003) J Exp Med , vol.198 , pp. 1875-1886
    • Chen, W.1    Jin, W.2    Hardegen, N.3
  • 44
    • 0037442264 scopus 로고    scopus 로고
    • Suppression of allogeneic T-cell proliferation by human marrow stromal cells: Implications in transplantation
    • Tse WT, Pendleton JD, Beyer WM et al. Suppression of allogeneic T-cell proliferation by human marrow stromal cells: implications in transplantation. Transplantation 2003;75:389-397.
    • (2003) Transplantation , vol.75 , pp. 389-397
    • Tse, W.T.1    Pendleton, J.D.2    Beyer, W.M.3
  • 45
    • 15044348816 scopus 로고    scopus 로고
    • Mesenchymal stem cell inhibit lymphocytes proliferation by mitogens and alloantigens by different mechanisms
    • Rasmusson I, Ringden O, Sundberg B et al. Mesenchymal stem cell inhibit lymphocytes proliferation by mitogens and alloantigens by different mechanisms. Exp Cell Res 2005;305:33-41.
    • (2005) Exp Cell Res , vol.305 , pp. 33-41
    • Rasmusson, I.1    Ringden, O.2    Sundberg, B.3
  • 46
    • 4344683220 scopus 로고    scopus 로고
    • Mesenchymal stem cell inhibit the expression of CD25 (interleukine-2 receptor) and CD38 on phytohaemagglutinin-activated lymphocytes
    • Le Blanc K, Rasmusson I, Gotherstrom C et al. Mesenchymal stem cell inhibit the expression of CD25 (interleukine-2 receptor) and CD38 on phytohaemagglutinin-activated lymphocytes. Scand J Immunol 2004;60:307-315.
    • (2004) Scand J Immunol , vol.60 , pp. 307-315
    • Le Blanc, K.1    Rasmusson, I.2    Gotherstrom, C.3
  • 47
    • 13544249606 scopus 로고    scopus 로고
    • Human mesenchymal stem cells modulate allogeneic immune cell responses
    • prepublished online October 19, doi 10.1182/blood-2004-04-1559
    • Aggarwal S, Pittenger MF. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood First Edition Paper, prepublished online October 19, 2004; doi 10.1182/blood-2004-04-1559.
    • (2004) Blood First Edition Paper
    • Aggarwal, S.1    Pittenger, M.F.2
  • 48
    • 15944376184 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells induce division arrest energy of activated T cells
    • Glennie S, Soeiro I, Dyson PJ et al. Bone marrow mesenchymal stem cells induce division arrest energy of activated T cells. Blood 2005;105:2821-2827.
    • (2005) Blood , vol.105 , pp. 2821-2827
    • Glennie, S.1    Soeiro, I.2    Dyson, P.J.3
  • 49
    • 18544364477 scopus 로고    scopus 로고
    • Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase
    • Munn DH, Sharma MD, Lee JR et al. Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase. Science 2002;297:1867-1870.
    • (2002) Science , vol.297 , pp. 1867-1870
    • Munn, D.H.1    Sharma, M.D.2    Lee, J.R.3
  • 50
    • 0037136328 scopus 로고    scopus 로고
    • Tryptophane-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2,3-dioxygenase
    • Frumento G, Rotondo R, Tonetti M et al. Tryptophane-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2,3-dioxygenase. J Exp Med 2002;196:459-468.
    • (2002) J Exp Med , vol.196 , pp. 459-468
    • Frumento, G.1    Rotondo, R.2    Tonetti, M.3
  • 51
    • 0346119234 scopus 로고    scopus 로고
    • Modulation of tryptophan catabolism by regulatory T cells
    • Fallarino F, Grohmann U, Hwang KW et al. Modulation of tryptophan catabolism by regulatory T cells. Nat Immunol 2003;4:1206-1212.
    • (2003) Nat Immunol , vol.4 , pp. 1206-1212
    • Fallarino, F.1    Grohmann, U.2    Hwang, K.W.3


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