메뉴 건너뛰기




Volumn , Issue , 2013, Pages 111-123

Connecting Phytochemicals, Epigenetics, and Healthy Aging: Is Metabolism the Missing Link?

Author keywords

Aging; Epigenetics; Inflammation; Metabolism; Oxidative stress; Phytochemicals; Xenohormesis

Indexed keywords


EID: 84902398972     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-397803-5.00010-1     Document Type: Chapter
Times cited : (3)

References (192)
  • 2
    • 55549147191 scopus 로고    scopus 로고
    • Personal genomes: The case of the missing heritability
    • Maher B. Personal genomes: The case of the missing heritability. Nature 2008, 456(7218):18-21.
    • (2008) Nature , vol.456 , Issue.7218 , pp. 18-21
    • Maher, B.1
  • 3
    • 40949124369 scopus 로고    scopus 로고
    • Environmental epigenetics and asthma: current concepts and call for studies
    • Miller R.L., Ho S.M. Environmental epigenetics and asthma: current concepts and call for studies. Am J Respir Crit Care Med 2008, 177(6):567-573.
    • (2008) Am J Respir Crit Care Med , vol.177 , Issue.6 , pp. 567-573
    • Miller, R.L.1    Ho, S.M.2
  • 4
    • 77953860649 scopus 로고    scopus 로고
    • The Role of Epigenetics in the Pathology of Diabetic Complications
    • Villeneuve L.M., Natarajan R. The Role of Epigenetics in the Pathology of Diabetic Complications. Am J Physiol Renal Physiol 2010, 299(1):F14-F25.
    • (2010) Am J Physiol Renal Physiol , vol.299 , Issue.1
    • Villeneuve, L.M.1    Natarajan, R.2
  • 5
    • 55949134303 scopus 로고    scopus 로고
    • DNA methylomes, histone codes and miRNAs: tying it all together
    • Guil S., Esteller M. DNA methylomes, histone codes and miRNAs: tying it all together. Int J Biochem Cell Biol 2009, 41(1):87-95.
    • (2009) Int J Biochem Cell Biol , vol.41 , Issue.1 , pp. 87-95
    • Guil, S.1    Esteller, M.2
  • 6
    • 77955480504 scopus 로고    scopus 로고
    • Epigenetics and environmental lung disease
    • Schwartz D.A. Epigenetics and environmental lung disease. Proc Am Thorac Soc 2010, 7(2):123-125.
    • (2010) Proc Am Thorac Soc , vol.7 , Issue.2 , pp. 123-125
    • Schwartz, D.A.1
  • 7
    • 46449087037 scopus 로고    scopus 로고
    • Effect of in utero and early-life conditions on adult health and disease
    • Gluckman P.D., Hanson M.A., Cooper C., Thornburg K.L. Effect of in utero and early-life conditions on adult health and disease. N Engl J Med 2008, 359(1):61-73.
    • (2008) N Engl J Med , vol.359 , Issue.1 , pp. 61-73
    • Gluckman, P.D.1    Hanson, M.A.2    Cooper, C.3    Thornburg, K.L.4
  • 8
    • 77950675978 scopus 로고    scopus 로고
    • Developmental origins of metabolic disease: life course and intergenerational perspectives
    • Godfrey K.M., Gluckman P.D., Hanson M.A. Developmental origins of metabolic disease: life course and intergenerational perspectives. Trends Endocrinol Metab 2010, 21(4):199-205.
    • (2010) Trends Endocrinol Metab , vol.21 , Issue.4 , pp. 199-205
    • Godfrey, K.M.1    Gluckman, P.D.2    Hanson, M.A.3
  • 9
    • 73849092036 scopus 로고    scopus 로고
    • MicroRNAs and cancer epigenetics: a macrorevolution
    • Davalos V., Esteller M. MicroRNAs and cancer epigenetics: a macrorevolution. Curr Opin Oncol 2010, 22(1):35-45.
    • (2010) Curr Opin Oncol , vol.22 , Issue.1 , pp. 35-45
    • Davalos, V.1    Esteller, M.2
  • 10
    • 33947315736 scopus 로고    scopus 로고
    • Cancer epigenomics: DNA methylomes and histone-modification maps
    • Esteller M. Cancer epigenomics: DNA methylomes and histone-modification maps. Nat Rev Genet 2007, 8(4):286-298.
    • (2007) Nat Rev Genet , vol.8 , Issue.4 , pp. 286-298
    • Esteller, M.1
  • 11
    • 40849139208 scopus 로고    scopus 로고
    • Epigenetics in cancer
    • Esteller M. Epigenetics in cancer. N Engl J Med 2008, 358(11):1148-1159.
    • (2008) N Engl J Med , vol.358 , Issue.11 , pp. 1148-1159
    • Esteller, M.1
  • 12
    • 0036144048 scopus 로고    scopus 로고
    • DNA methylation patterns and epigenetic memory
    • Bird A. DNA methylation patterns and epigenetic memory. Genes Dev 2002, 16(1):6-21.
    • (2002) Genes Dev , vol.16 , Issue.1 , pp. 6-21
    • Bird, A.1
  • 13
    • 70350046301 scopus 로고    scopus 로고
    • Rethinking how DNA methylation patterns are maintained
    • Jones P.A., Liang G. Rethinking how DNA methylation patterns are maintained. Nat Rev Genet 2009, 10(11):805-811.
    • (2009) Nat Rev Genet , vol.10 , Issue.11 , pp. 805-811
    • Jones, P.A.1    Liang, G.2
  • 14
    • 77249170184 scopus 로고    scopus 로고
    • Establishing, maintaining and modifying DNA methylation patterns in plants and animals
    • Law J.A., Jacobsen S.E. Establishing, maintaining and modifying DNA methylation patterns in plants and animals. Nat Rev Genet 2010, 11(3):204-220.
    • (2010) Nat Rev Genet , vol.11 , Issue.3 , pp. 204-220
    • Law, J.A.1    Jacobsen, S.E.2
  • 15
    • 79960117245 scopus 로고    scopus 로고
    • Hypothesis: Environmental regulation of 5-hydroxymethylcytosine by oxidative stress
    • Wang L., Chia N.C., Lu X., Ruden D.M. Hypothesis: Environmental regulation of 5-hydroxymethylcytosine by oxidative stress. Epigenetics 2011, 6(7):853-856.
    • (2011) Epigenetics , vol.6 , Issue.7 , pp. 853-856
    • Wang, L.1    Chia, N.C.2    Lu, X.3    Ruden, D.M.4
  • 16
    • 38149045693 scopus 로고    scopus 로고
    • DNA Oxidation as Triggered by H3K9me2 Demethylation Drives Estrogen-Induced Gene Expression
    • Perillo B., Ombra M.N., Bertoni A., Cuozzo C., Sacchetti S., Sasso A., et al. DNA Oxidation as Triggered by H3K9me2 Demethylation Drives Estrogen-Induced Gene Expression. Science 2008, 319(5860):202-206.
    • (2008) Science , vol.319 , Issue.5860 , pp. 202-206
    • Perillo, B.1    Ombra, M.N.2    Bertoni, A.3    Cuozzo, C.4    Sacchetti, S.5    Sasso, A.6
  • 17
    • 84861138595 scopus 로고    scopus 로고
    • Age-related increase in levels of 5-hydroxymethylcytosine in mouse hippocampus is prevented by caloric restriction
    • Chouliaras L., van den Hove D.L., Kenis G., Keitel S., Hof P.R., van Os J., et al. Age-related increase in levels of 5-hydroxymethylcytosine in mouse hippocampus is prevented by caloric restriction. Curr Alzheimer Res 2012, 9(5):536-544.
    • (2012) Curr Alzheimer Res , vol.9 , Issue.5 , pp. 536-544
    • Chouliaras, L.1    van den Hove, D.L.2    Kenis, G.3    Keitel, S.4    Hof, P.R.5    van Os, J.6
  • 18
    • 80052037691 scopus 로고    scopus 로고
    • Epigenetic regulation of caloric restriction in aging
    • Li Y., Daniel M., Tollefsbol T.O. Epigenetic regulation of caloric restriction in aging. BMC Medicine 2011, 9(1):98.
    • (2011) BMC Medicine , vol.9 , Issue.1 , pp. 98
    • Li, Y.1    Daniel, M.2    Tollefsbol, T.O.3
  • 20
    • 77953995002 scopus 로고    scopus 로고
    • Covalent histone modifications-miswritten, misinterpreted and mis-erased in human cancers
    • Chi P., Allis C.D., Wang G.G. Covalent histone modifications-miswritten, misinterpreted and mis-erased in human cancers. Nat Rev Cancer 2010, 10(7):457-469.
    • (2010) Nat Rev Cancer , vol.10 , Issue.7 , pp. 457-469
    • Chi, P.1    Allis, C.D.2    Wang, G.G.3
  • 21
    • 78650747491 scopus 로고    scopus 로고
    • Discovery and characterization of chromatin states for systematic annotation of the human genome
    • Ernst J., Kellis M. Discovery and characterization of chromatin states for systematic annotation of the human genome. Nat Biotechnol 2010, 28(8):817-825.
    • (2010) Nat Biotechnol , vol.28 , Issue.8 , pp. 817-825
    • Ernst, J.1    Kellis, M.2
  • 22
    • 79955583542 scopus 로고    scopus 로고
    • Mapping and analysis of chromatin state dynamics in nine human cell types
    • Ernst J., Kheradpour P., Mikkelsen T.S., Shoresh N., Ward L.D., Epstein C.B., et al. Mapping and analysis of chromatin state dynamics in nine human cell types. Nature 2011, 473(7345):43-49.
    • (2011) Nature , vol.473 , Issue.7345 , pp. 43-49
    • Ernst, J.1    Kheradpour, P.2    Mikkelsen, T.S.3    Shoresh, N.4    Ward, L.D.5    Epstein, C.B.6
  • 23
    • 79957845867 scopus 로고    scopus 로고
    • Linking nutrient metabolism to epigenetics
    • Luo J., Kuo M.H. Linking nutrient metabolism to epigenetics. Cell Science Reviews 2009, 6:49-54.
    • (2009) Cell Science Reviews , vol.6 , pp. 49-54
    • Luo, J.1    Kuo, M.H.2
  • 24
    • 78649725166 scopus 로고    scopus 로고
    • Mammalian circadian clock and metabolism-the epigenetic link
    • Bellet M.M., Sassone-Corsi P. Mammalian circadian clock and metabolism-the epigenetic link. J Cell Sci 2010, 123(Pt 22):3837-3848.
    • (2010) J Cell Sci , vol.123 , Issue.PART 22 , pp. 3837-3848
    • Bellet, M.M.1    Sassone-Corsi, P.2
  • 25
    • 78650720493 scopus 로고    scopus 로고
    • Nicotinamide adenine dinucleotide (NAD)-regulated DNA methylation alters CCCTC-binding factor (CTCF)/cohesin binding and transcription at the BDNF locus
    • Chang J., Zhang B., Heath H., Galjart N., Wang X., Milbrandt J. Nicotinamide adenine dinucleotide (NAD)-regulated DNA methylation alters CCCTC-binding factor (CTCF)/cohesin binding and transcription at the BDNF locus. Proc Natl Acad Sci U S A 2010, 107(50):21836-21841.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , Issue.50 , pp. 21836-21841
    • Chang, J.1    Zhang, B.2    Heath, H.3    Galjart, N.4    Wang, X.5    Milbrandt, J.6
  • 26
    • 77956235100 scopus 로고    scopus 로고
    • Bioenergetics and the epigenome: interface between the environment and genes in common diseases
    • Wallace D.C. Bioenergetics and the epigenome: interface between the environment and genes in common diseases. Dev Disabil Res Rev 2010, 16(2):114-119.
    • (2010) Dev Disabil Res Rev , vol.16 , Issue.2 , pp. 114-119
    • Wallace, D.C.1
  • 27
    • 77955891911 scopus 로고    scopus 로고
    • The epigenome and the mitochondrion: bioenergetics and the environment [corrected]
    • Wallace D.C. The epigenome and the mitochondrion: bioenergetics and the environment [corrected]. Genes Dev 2010, 24(15):1571-1573.
    • (2010) Genes Dev , vol.24 , Issue.15 , pp. 1571-1573
    • Wallace, D.C.1
  • 28
    • 67649637998 scopus 로고    scopus 로고
    • Chromatin places metabolism center stage
    • Ladurner A.G. Chromatin places metabolism center stage. Cell 2009, 138(1):18-20.
    • (2009) Cell , vol.138 , Issue.1 , pp. 18-20
    • Ladurner, A.G.1
  • 29
    • 84870746218 scopus 로고    scopus 로고
    • Modifying metabolically sensitive histone marks by inhibiting glutamine metabolism affects gene expression and alters cancer cell phenotype
    • 1413-2
    • Simpson N.E., Tryndyak V.P., Pogribna M., Beland F.A., Pogribny I.P. Modifying metabolically sensitive histone marks by inhibiting glutamine metabolism affects gene expression and alters cancer cell phenotype. Epigenetics 2012, 7(12). 1413-2.
    • (2012) Epigenetics , vol.7 , Issue.12
    • Simpson, N.E.1    Tryndyak, V.P.2    Pogribna, M.3    Beland, F.A.4    Pogribny, I.P.5
  • 30
    • 84873310426 scopus 로고    scopus 로고
    • Genome-wide Chromatin State Transitions Associated with Developmental and Environmental Cues
    • Zhu J., Adli M., Zou J.Y., Verstappen G., Coyne M., Zhang X., et al. Genome-wide Chromatin State Transitions Associated with Developmental and Environmental Cues. Cell 2013, 152(3):642-654.
    • (2013) Cell , vol.152 , Issue.3 , pp. 642-654
    • Zhu, J.1    Adli, M.2    Zou, J.Y.3    Verstappen, G.4    Coyne, M.5    Zhang, X.6
  • 31
    • 84865790047 scopus 로고    scopus 로고
    • An integrated encyclopedia of DNA elements in the human genome
    • Dunham I., Kundaje A., Aldred S.F., Collins P.J., Davis C.A., Doyle F., et al. An integrated encyclopedia of DNA elements in the human genome. Nature 2012, 489(7414):57-74.
    • (2012) Nature , vol.489 , Issue.7414 , pp. 57-74
    • Dunham, I.1    Kundaje, A.2    Aldred, S.F.3    Collins, P.J.4    Davis, C.A.5    Doyle, F.6
  • 32
    • 49649122472 scopus 로고    scopus 로고
    • AHEAD with an international human epigenome project
    • Moving
    • Moving AHEAD with an international human epigenome project. Nature 2008, 454(7205):711-715.
    • (2008) Nature , vol.454 , Issue.7205 , pp. 711-715
  • 34
    • 84873576566 scopus 로고    scopus 로고
    • Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis
    • Liu Y., Aryee M.J., Padyukov L., Fallin M.D., Hesselberg E., Runarsson A., et al. Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis. Nat Biotechnol 2013, 31(2):142-147.
    • (2013) Nat Biotechnol , vol.31 , Issue.2 , pp. 142-147
    • Liu, Y.1    Aryee, M.J.2    Padyukov, L.3    Fallin, M.D.4    Hesselberg, E.5    Runarsson, A.6
  • 35
    • 70149099610 scopus 로고    scopus 로고
    • Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context
    • Christensen B.C., Houseman E.A., Marsit C.J., Zheng S., Wrensch M.R., Wiemels J.L., et al. Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context. PLoS Genet 2009, 5(8):e1000602.
    • (2009) PLoS Genet , vol.5 , Issue.8
    • Christensen, B.C.1    Houseman, E.A.2    Marsit, C.J.3    Zheng, S.4    Wrensch, M.R.5    Wiemels, J.L.6
  • 36
    • 79960121131 scopus 로고    scopus 로고
    • The influence of aging, environmental exposures and local sequence features on the variation of DNA methylation in blood
    • Langevin S.M., Houseman E.A., Christensen B.C., Wiencke J.K., Nelson H.H., Karagas M.R., et al. The influence of aging, environmental exposures and local sequence features on the variation of DNA methylation in blood. Epigenetics 2011, 6(7):908-919.
    • (2011) Epigenetics , vol.6 , Issue.7 , pp. 908-919
    • Langevin, S.M.1    Houseman, E.A.2    Christensen, B.C.3    Wiencke, J.K.4    Nelson, H.H.5    Karagas, M.R.6
  • 38
    • 84855400734 scopus 로고    scopus 로고
    • Genome-wide survey reveals predisposing diabetes type 2-related DNA methylation variations in human peripheral blood
    • Toperoff G., Aran D., Kark J.D., Rosenberg M., Dubnikov T., Nissan B., et al. Genome-wide survey reveals predisposing diabetes type 2-related DNA methylation variations in human peripheral blood. Hum Mol Genet 2012, 21(2):371-383.
    • (2012) Hum Mol Genet , vol.21 , Issue.2 , pp. 371-383
    • Toperoff, G.1    Aran, D.2    Kark, J.D.3    Rosenberg, M.4    Dubnikov, T.5    Nissan, B.6
  • 39
    • 84868245579 scopus 로고    scopus 로고
    • MAOA promoter methylation and susceptibility to carotid atherosclerosis: role of familial factors in a monozygotic twin sample
    • Zhao J., Forsberg C.W., Goldberg J., Smith N.L., Vaccarino V. MAOA promoter methylation and susceptibility to carotid atherosclerosis: role of familial factors in a monozygotic twin sample. BMC Med Genet 2012, 13:100.
    • (2012) BMC Med Genet , vol.13 , pp. 100
    • Zhao, J.1    Forsberg, C.W.2    Goldberg, J.3    Smith, N.L.4    Vaccarino, V.5
  • 40
    • 77957666255 scopus 로고    scopus 로고
    • Histone methyl transferases and demethylases; can they link metabolism and transcription?
    • Teperino R., Schoonjans K., Auwerx J. Histone methyl transferases and demethylases; can they link metabolism and transcription?. Cell Metab 2010, 12(4):321-327.
    • (2010) Cell Metab , vol.12 , Issue.4 , pp. 321-327
    • Teperino, R.1    Schoonjans, K.2    Auwerx, J.3
  • 41
    • 77956419439 scopus 로고    scopus 로고
    • Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism
    • Bonuccelli G., Tsirigos A., Whitaker-Menezes D., Pavlides S., Pestell R.G., Chiavarina B., et al. Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism. Cell Cycle 2010, 9(17):3506-3514.
    • (2010) Cell Cycle , vol.9 , Issue.17 , pp. 3506-3514
    • Bonuccelli, G.1    Tsirigos, A.2    Whitaker-Menezes, D.3    Pavlides, S.4    Pestell, R.G.5    Chiavarina, B.6
  • 42
    • 79954537559 scopus 로고    scopus 로고
    • Ketones and lactate increase cancer cell "stemness," driving recurrence, metastasis and poor clinical outcome in breast cancer: Achieving personalized medicine via Metabolo-Genomics
    • Martinez-Outschoorn U.E., Prisco M., Ertel A., Tsirigos A., Lin Z., Pavlides S., et al. Ketones and lactate increase cancer cell "stemness," driving recurrence, metastasis and poor clinical outcome in breast cancer: Achieving personalized medicine via Metabolo-Genomics. Cell Cycle 2011, 10(8):1271-1286.
    • (2011) Cell Cycle , vol.10 , Issue.8 , pp. 1271-1286
    • Martinez-Outschoorn, U.E.1    Prisco, M.2    Ertel, A.3    Tsirigos, A.4    Lin, Z.5    Pavlides, S.6
  • 43
    • 78650019179 scopus 로고    scopus 로고
    • Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation
    • Figueroa M.E., Abdel-Wahab O., Lu C., Ward P.S., Patel J., Shih A., et al. Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer Cell 2010, 18(6):553-567.
    • (2010) Cancer Cell , vol.18 , Issue.6 , pp. 553-567
    • Figueroa, M.E.1    Abdel-Wahab, O.2    Lu, C.3    Ward, P.S.4    Patel, J.5    Shih, A.6
  • 45
    • 66249122423 scopus 로고    scopus 로고
    • Biochemistry. A glucose-to-gene link
    • Rathmell J.C., Newgard C.B. Biochemistry. A glucose-to-gene link. Science 2009, 324(5930):1021-1022.
    • (2009) Science , vol.324 , Issue.5930 , pp. 1021-1022
    • Rathmell, J.C.1    Newgard, C.B.2
  • 46
    • 84856090681 scopus 로고    scopus 로고
    • Connecting Threads: Epigenetics and Metabolism
    • Katada S., Imhof A., Sassone-Corsi P. Connecting Threads: Epigenetics and Metabolism. Cell 2012, 148(1-2):24-28.
    • (2012) Cell , vol.148 , Issue.1-2 , pp. 24-28
    • Katada, S.1    Imhof, A.2    Sassone-Corsi, P.3
  • 47
    • 84864309100 scopus 로고    scopus 로고
    • Clocks, Metabolism, and the Epigenome
    • Feng D., Lazar Mitchell A. Clocks, Metabolism, and the Epigenome. Mol Cell 2012, 47(2):158-167.
    • (2012) Mol Cell , vol.47 , Issue.2 , pp. 158-167
    • Feng, D.1    Lazar Mitchell, A.2
  • 48
    • 84876784115 scopus 로고    scopus 로고
    • Epigenetic flexibility in metabolic regulation: disease cause and prevention?
    • pii: S0962-8924(12)00222-X. [Epub ahead of print]
    • Kirchner H., Osler M.E., Krook A., Zierath J.R. Epigenetic flexibility in metabolic regulation: disease cause and prevention?. Trends Cell Biol 2012, pii: S0962-8924(12)00222-X. http://dx.doi.org.10.1016/j.tcb.2012.11.008. [Epub ahead of print].
    • (2012) Trends Cell Biol
    • Kirchner, H.1    Osler, M.E.2    Krook, A.3    Zierath, J.R.4
  • 50
    • 79955055958 scopus 로고    scopus 로고
    • Epigenetics in cardiovascular disease
    • Shirodkar A.V., Marsden P.A. Epigenetics in cardiovascular disease. Curr Opin Cardiol 2011, 26(3):209-215.
    • (2011) Curr Opin Cardiol , vol.26 , Issue.3 , pp. 209-215
    • Shirodkar, A.V.1    Marsden, P.A.2
  • 51
    • 77956058729 scopus 로고    scopus 로고
    • Epigenetics and cardiovascular disease
    • Ordovas J.M., Smith C.E. Epigenetics and cardiovascular disease. Nat Rev Cardiol 2010, 7(9):510-519.
    • (2010) Nat Rev Cardiol , vol.7 , Issue.9 , pp. 510-519
    • Ordovas, J.M.1    Smith, C.E.2
  • 52
    • 78449244155 scopus 로고    scopus 로고
    • The epigenetic basis of the Warburg effect
    • Wang X., Jin H. The epigenetic basis of the Warburg effect. Epigenetics 2010, 5(7):566-568.
    • (2010) Epigenetics , vol.5 , Issue.7 , pp. 566-568
    • Wang, X.1    Jin, H.2
  • 53
    • 75149159101 scopus 로고    scopus 로고
    • Warburg effect revisited: an epigenetic link between glycolysis and gastric carcinogenesis
    • Liu X., Wang X., Zhang J., Lam E.K., Shin V.Y., Cheng A.S., et al. Warburg effect revisited: an epigenetic link between glycolysis and gastric carcinogenesis. Oncogene 2010, 29(3):442-450.
    • (2010) Oncogene , vol.29 , Issue.3 , pp. 442-450
    • Liu, X.1    Wang, X.2    Zhang, J.3    Lam, E.K.4    Shin, V.Y.5    Cheng, A.S.6
  • 54
    • 84858793036 scopus 로고    scopus 로고
    • Metabolism: unmasking an oncometabolite
    • McCarthy N. Metabolism: unmasking an oncometabolite. Nat Rev Cancer 2012, 12(4):229.
    • (2012) Nat Rev Cancer , vol.12 , Issue.4 , pp. 229
    • McCarthy, N.1
  • 55
    • 79955547561 scopus 로고    scopus 로고
    • The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
    • Chowdhury R., Yeoh K.K., Tian Y.M., Hillringhaus L., Bagg E.A., Rose N.R., et al. The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases. EMBO Rep 2011, 12(5):463-469.
    • (2011) EMBO Rep , vol.12 , Issue.5 , pp. 463-469
    • Chowdhury, R.1    Yeoh, K.K.2    Tian, Y.M.3    Hillringhaus, L.4    Bagg, E.A.5    Rose, N.R.6
  • 57
    • 82055161827 scopus 로고    scopus 로고
    • Cancer chemoprevention by targeting the epigenome
    • Huang J., Plass C., Gerhauser C. Cancer chemoprevention by targeting the epigenome. Curr Drug Targets 2011, 12(13):1925-1956.
    • (2011) Curr Drug Targets , vol.12 , Issue.13 , pp. 1925-1956
    • Huang, J.1    Plass, C.2    Gerhauser, C.3
  • 58
    • 78049440083 scopus 로고    scopus 로고
    • Nature or nurture: let food be your epigenetic medicine in chronic inflammatory disorders
    • Vel Szic K.S., Ndlovu M.N., Haegeman G., Vanden Berghe W. Nature or nurture: let food be your epigenetic medicine in chronic inflammatory disorders. Biochem Pharmacol 2010, 80(12):1816-1832.
    • (2010) Biochem Pharmacol , vol.80 , Issue.12 , pp. 1816-1832
    • Vel Szic, K.S.1    Ndlovu, M.N.2    Haegeman, G.3    Vanden Berghe, W.4
  • 59
    • 33751251702 scopus 로고    scopus 로고
    • Germ cells carry the epigenetic benefits of grandmother's diet
    • Cooney C.A. Germ cells carry the epigenetic benefits of grandmother's diet. Proc Natl Acad Sci U S A 2006, 103(46):17071-17072.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.46 , pp. 17071-17072
    • Cooney, C.A.1
  • 60
    • 73249142471 scopus 로고    scopus 로고
    • Shaping adult phenotypes through early life environments
    • Weaver I.C. Shaping adult phenotypes through early life environments. Birth Defects Res Part C Embryo Today 2009, 87(4):314-326.
    • (2009) Birth Defects Res Part C Embryo Today , vol.87 , Issue.4 , pp. 314-326
    • Weaver, I.C.1
  • 61
    • 77955627637 scopus 로고    scopus 로고
    • Nutrition, Epigenetics, and Developmental Plasticity: Implications for Understanding Human Diseas
    • Burdge G.C., Lillycrop K.A. Nutrition, Epigenetics, and Developmental Plasticity: Implications for Understanding Human Diseas. Annu Rev Nutr 2010, 30:315-339.
    • (2010) Annu Rev Nutr , vol.30 , pp. 315-339
    • Burdge, G.C.1    Lillycrop, K.A.2
  • 62
    • 77954324619 scopus 로고    scopus 로고
    • Epigenetics and environment: a complex relationship
    • Aguilera O., Fernandez A.F., Munoz A., Fraga M.F. Epigenetics and environment: a complex relationship. J Appl Physiol 2010, 109(1):243-251.
    • (2010) J Appl Physiol , vol.109 , Issue.1 , pp. 243-251
    • Aguilera, O.1    Fernandez, A.F.2    Munoz, A.3    Fraga, M.F.4
  • 64
    • 33947611552 scopus 로고    scopus 로고
    • Nutri-epigenomics: lifelong remodelling of our epigenomes by nutritional and metabolic factors and beyond
    • Gallou-Kabani C., Vige A., Gross M.S., Junien C. Nutri-epigenomics: lifelong remodelling of our epigenomes by nutritional and metabolic factors and beyond. Clin Chem Lab Med 2007, 45(3):321-327.
    • (2007) Clin Chem Lab Med , vol.45 , Issue.3 , pp. 321-327
    • Gallou-Kabani, C.1    Vige, A.2    Gross, M.S.3    Junien, C.4
  • 65
    • 20344385787 scopus 로고    scopus 로고
    • Epigenetic transgenerational actions of endocrine disruptors and male fertility
    • Anway M.D., Cupp A.S., Uzumcu M., Skinner M.K. Epigenetic transgenerational actions of endocrine disruptors and male fertility. Science 2005, 308(5727):1466-1469.
    • (2005) Science , vol.308 , Issue.5727 , pp. 1466-1469
    • Anway, M.D.1    Cupp, A.S.2    Uzumcu, M.3    Skinner, M.K.4
  • 66
    • 33646815647 scopus 로고    scopus 로고
    • Epigenetic transgenerational actions of endocrine disruptors
    • Anway M.D., Skinner M.K. Epigenetic transgenerational actions of endocrine disruptors. Endocrinology 2006, 147(6 Suppl):S43-S49.
    • (2006) Endocrinology , vol.147 , Issue.6 SUPPL
    • Anway, M.D.1    Skinner, M.K.2
  • 67
    • 33947310031 scopus 로고    scopus 로고
    • Environmental epigenomics and disease susceptibility
    • Jirtle R.L., Skinner M.K. Environmental epigenomics and disease susceptibility. Nat Rev Genet 2007, 8(4):253-262.
    • (2007) Nat Rev Genet , vol.8 , Issue.4 , pp. 253-262
    • Jirtle, R.L.1    Skinner, M.K.2
  • 68
    • 0026515582 scopus 로고
    • The maternal and fetal origins of cardiovascular disease
    • Barker D.J., Martyn C.N. The maternal and fetal origins of cardiovascular disease. J Epidemiol Community Health 1992, 46(1):8-11.
    • (1992) J Epidemiol Community Health , vol.46 , Issue.1 , pp. 8-11
    • Barker, D.J.1    Martyn, C.N.2
  • 69
    • 84926108427 scopus 로고    scopus 로고
    • Diet, nutrition and modulation of genomic expression in fetal origins of adult disease
    • Jackson A.A., Burdge G.C., Lillycrop K.A. Diet, nutrition and modulation of genomic expression in fetal origins of adult disease. World Rev Nutr Diet 2010, 101:56-72.
    • (2010) World Rev Nutr Diet , vol.101 , pp. 56-72
    • Jackson, A.A.1    Burdge, G.C.2    Lillycrop, K.A.3
  • 70
    • 77950357572 scopus 로고    scopus 로고
    • Fetal programming: link between early nutrition, DNA methylation, and complex diseases
    • Chmurzynska A. Fetal programming: link between early nutrition, DNA methylation, and complex diseases. Nutr Rev 2010, 68(2):87-98.
    • (2010) Nutr Rev , vol.68 , Issue.2 , pp. 87-98
    • Chmurzynska, A.1
  • 71
    • 59249107052 scopus 로고    scopus 로고
    • DNA methylation profiles in monozygotic and dizygotic twins
    • Kaminsky Z.A., Tang T., Wang S.C., Ptak C., Oh G.H., Wong A.H., et al. DNA methylation profiles in monozygotic and dizygotic twins. Nat Genet 2009, 41(2):240-245.
    • (2009) Nat Genet , vol.41 , Issue.2 , pp. 240-245
    • Kaminsky, Z.A.1    Tang, T.2    Wang, S.C.3    Ptak, C.4    Oh, G.H.5    Wong, A.H.6
  • 72
    • 33745752370 scopus 로고    scopus 로고
    • Epigenetics and twins: three variations on the theme
    • Petronis A. Epigenetics and twins: three variations on the theme. Trends Genet 2006, 22(7):347-350.
    • (2006) Trends Genet , vol.22 , Issue.7 , pp. 347-350
    • Petronis, A.1
  • 73
    • 33645633542 scopus 로고    scopus 로고
    • Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome
    • Dolinoy D.C., Weidman J.R., Waterland R.A., Jirtle R.L. Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome. Environ Health Perspect 2006, 114(4):567-572.
    • (2006) Environ Health Perspect , vol.114 , Issue.4 , pp. 567-572
    • Dolinoy, D.C.1    Weidman, J.R.2    Waterland, R.A.3    Jirtle, R.L.4
  • 74
    • 39749171775 scopus 로고    scopus 로고
    • Environmental epigenomics in human health and disease
    • Dolinoy D.C., Jirtle R.L. Environmental epigenomics in human health and disease. Environ Mol Mutagen 2008, 49(1):4-8.
    • (2008) Environ Mol Mutagen , vol.49 , Issue.1 , pp. 4-8
    • Dolinoy, D.C.1    Jirtle, R.L.2
  • 75
    • 58549110426 scopus 로고    scopus 로고
    • Is epigenetics an important link between early life events and adult disease?
    • Waterland R.A. Is epigenetics an important link between early life events and adult disease?. Horm Res 2009, 71(Suppl. 1):13-16.
    • (2009) Horm Res , vol.71 , Issue.SUPPL. 1 , pp. 13-16
    • Waterland, R.A.1
  • 77
    • 79952697268 scopus 로고    scopus 로고
    • Epigenomic communication systems in humans and honey bees: From molecules to behavior
    • Gabor Miklos G.L., Maleszka R. Epigenomic communication systems in humans and honey bees: From molecules to behavior. Horm Behav 2010, 59(3):399-406.
    • (2010) Horm Behav , vol.59 , Issue.3 , pp. 399-406
    • Gabor Miklos, G.L.1    Maleszka, R.2
  • 78
    • 41349085806 scopus 로고    scopus 로고
    • Nutritional control of reproductive status in honeybees via DNA methylation
    • Kucharski R., Maleszka J., Foret S., Maleszka R. Nutritional control of reproductive status in honeybees via DNA methylation. Science 2008, 319(5871):1827-1830.
    • (2008) Science , vol.319 , Issue.5871 , pp. 1827-1830
    • Kucharski, R.1    Maleszka, J.2    Foret, S.3    Maleszka, R.4
  • 79
    • 54949122508 scopus 로고    scopus 로고
    • Epigenetic integration of environmental and genomic signals in honey bees: the critical interplay of nutritional, brain and reproductive networks
    • Maleszka R. Epigenetic integration of environmental and genomic signals in honey bees: the critical interplay of nutritional, brain and reproductive networks. Epigenetics 2008, 3(4):188-192.
    • (2008) Epigenetics , vol.3 , Issue.4 , pp. 188-192
    • Maleszka, R.1
  • 80
    • 70449715419 scopus 로고    scopus 로고
    • Epigenetic regulation of the honey bee transcriptome: unravelling the nature of methylated genes
    • Foret S., Kucharski R., Pittelkow Y., Lockett G.A., Maleszka R. Epigenetic regulation of the honey bee transcriptome: unravelling the nature of methylated genes. BMC Genomics 2009, 10:472.
    • (2009) BMC Genomics , vol.10 , pp. 472
    • Foret, S.1    Kucharski, R.2    Pittelkow, Y.3    Lockett, G.A.4    Maleszka, R.5
  • 81
    • 84859465140 scopus 로고    scopus 로고
    • DNA methylation dynamics, metabolic fluxes, gene splicing, and alternative phenotypes in honey bees
    • Foret S., Kucharski R., Pellegrini M., Feng S., Jacobsen S.E., Robinson G.E., et al. DNA methylation dynamics, metabolic fluxes, gene splicing, and alternative phenotypes in honey bees. Proc Natl Acad Sci U S A 2012, 109(13):4968-4973.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , Issue.13 , pp. 4968-4973
    • Foret, S.1    Kucharski, R.2    Pellegrini, M.3    Feng, S.4    Jacobsen, S.E.5    Robinson, G.E.6
  • 82
    • 79957613433 scopus 로고    scopus 로고
    • Royalactin induces queen differentiation in honeybees
    • Kamakura M. Royalactin induces queen differentiation in honeybees. Nature 2011, 473(7348):478-483.
    • (2011) Nature , vol.473 , Issue.7348 , pp. 478-483
    • Kamakura, M.1
  • 83
    • 77953137107 scopus 로고    scopus 로고
    • The curious case of aging plasticity in honey bees
    • Münch D., Amdam G.V. The curious case of aging plasticity in honey bees. FEBS Letters 2010, 584(12):2496-2503.
    • (2010) FEBS Letters , vol.584 , Issue.12 , pp. 2496-2503
    • Münch, D.1    Amdam, G.V.2
  • 84
    • 84873654582 scopus 로고    scopus 로고
    • Contribution of Lipids in Honeybee (Apis mellifera) Royal Jelly to Health
    • Li X., Huang C., Xue Y. Contribution of Lipids in Honeybee (Apis mellifera) Royal Jelly to Health. J Med Food 2013, 16(2):96-102.
    • (2013) J Med Food , vol.16 , Issue.2 , pp. 96-102
    • Li, X.1    Huang, C.2    Xue, Y.3
  • 85
    • 49649092218 scopus 로고    scopus 로고
    • Transgenerational effects of prenatal exposure to the Dutch famine on neonatal adiposity and health in later life
    • Painter R.C., Osmond C., Gluckman P., Hanson M., Phillips D.I., Roseboom T.J. Transgenerational effects of prenatal exposure to the Dutch famine on neonatal adiposity and health in later life. BJOG 2008, 115(10):1243-1249.
    • (2008) BJOG , vol.115 , Issue.10 , pp. 1243-1249
    • Painter, R.C.1    Osmond, C.2    Gluckman, P.3    Hanson, M.4    Phillips, D.I.5    Roseboom, T.J.6
  • 86
    • 65349130583 scopus 로고    scopus 로고
    • Transgenerational effects of prenatal exposure to the Dutch famine
    • author reply
    • Lumey L.H., Stein A.D. Transgenerational effects of prenatal exposure to the Dutch famine. BJOG 2009, 116(6):868. author reply.
    • (2009) BJOG , vol.116 , Issue.6 , pp. 868
    • Lumey, L.H.1    Stein, A.D.2
  • 87
    • 33746911576 scopus 로고    scopus 로고
    • The Dutch famine and its long-term consequences for adult health
    • Roseboom T., de Rooij S., Painter R. The Dutch famine and its long-term consequences for adult health. Early Hum Dev 2006, 82(8):485-491.
    • (2006) Early Hum Dev , vol.82 , Issue.8 , pp. 485-491
    • Roseboom, T.1    de Rooij, S.2    Painter, R.3
  • 88
    • 31344473642 scopus 로고    scopus 로고
    • Epigenetics: sins of the fathers, and their fathers
    • Whitelaw E. Epigenetics: sins of the fathers, and their fathers. Eur J Hum Genet 2006, 14(2):131-132.
    • (2006) Eur J Hum Genet , vol.14 , Issue.2 , pp. 131-132
    • Whitelaw, E.1
  • 89
    • 0036862451 scopus 로고    scopus 로고
    • Cardiovascular and diabetes mortality determined by nutrition during parents' and grandparents' slow growth period
    • Kaati G., Bygren L.O., Edvinsson S. Cardiovascular and diabetes mortality determined by nutrition during parents' and grandparents' slow growth period. Eur J Hum Genet 2002, 10(11):682-688.
    • (2002) Eur J Hum Genet , vol.10 , Issue.11 , pp. 682-688
    • Kaati, G.1    Bygren, L.O.2    Edvinsson, S.3
  • 90
    • 19444378511 scopus 로고    scopus 로고
    • Developmental processes and the induction of cardiovascular function: conceptual aspects
    • Hanson M.A., Gluckman P.D. Developmental processes and the induction of cardiovascular function: conceptual aspects. J Physiol 2005, 565(Pt 1):27-34.
    • (2005) J Physiol , vol.565 , Issue.PART 1 , pp. 27-34
    • Hanson, M.A.1    Gluckman, P.D.2
  • 91
    • 59749094084 scopus 로고    scopus 로고
    • Epigenetic histone acetylation modifiers in vascular remodelling: new targets for therapy in cardiovascular disease
    • Pons D., de Vries F.R., van den Elsen P.J., Heijmans B.T., Quax P.H., Jukema J.W. Epigenetic histone acetylation modifiers in vascular remodelling: new targets for therapy in cardiovascular disease. European Heart Journal 2009, 30(3):266-277.
    • (2009) European Heart Journal , vol.30 , Issue.3 , pp. 266-277
    • Pons, D.1    de Vries, F.R.2    van den Elsen, P.J.3    Heijmans, B.T.4    Quax, P.H.5    Jukema, J.W.6
  • 93
    • 42049098600 scopus 로고    scopus 로고
    • Heterogeneity of human macrophages in culture and in atherosclerotic plaques
    • Waldo S.W., Li Y., Buono C., Zhao B., Billings E.M., Chang J., et al. Heterogeneity of human macrophages in culture and in atherosclerotic plaques. Am J Pathol 2008, 172(4):1112-1126.
    • (2008) Am J Pathol , vol.172 , Issue.4 , pp. 1112-1126
    • Waldo, S.W.1    Li, Y.2    Buono, C.3    Zhao, B.4    Billings, E.M.5    Chang, J.6
  • 94
    • 73349117486 scopus 로고    scopus 로고
    • Atherosclerosis risk factors can impose aberrant DNA methylation patterns: a tale of traffic and homocysteine
    • Lund G., Zaina S. Atherosclerosis risk factors can impose aberrant DNA methylation patterns: a tale of traffic and homocysteine. Curr Opin Lipidol 2009, 20(5):448-449.
    • (2009) Curr Opin Lipidol , vol.20 , Issue.5 , pp. 448-449
    • Lund, G.1    Zaina, S.2
  • 95
    • 64549109780 scopus 로고    scopus 로고
    • Epigenetics, transgenerational effects and risk factors for atherosclerosis
    • Lund G., Zaina S. Epigenetics, transgenerational effects and risk factors for atherosclerosis. Curr Opin Lipidol 2009, 20(2):150-151.
    • (2009) Curr Opin Lipidol , vol.20 , Issue.2 , pp. 150-151
    • Lund, G.1    Zaina, S.2
  • 97
    • 33646378412 scopus 로고    scopus 로고
    • Mining literature for a comprehensive pathway analysis: a case study for retrieval of homocysteine related genes for genetic and epigenetic studies
    • Sharma P., Senthilkumar R.D., Brahmachari V., Sundaramoorthy E., Mahajan A., Sharma A., et al. Mining literature for a comprehensive pathway analysis: a case study for retrieval of homocysteine related genes for genetic and epigenetic studies. Lipids Health Dis 2006, 5:1.
    • (2006) Lipids Health Dis , vol.5 , pp. 1
    • Sharma, P.1    Senthilkumar, R.D.2    Brahmachari, V.3    Sundaramoorthy, E.4    Mahajan, A.5    Sharma, A.6
  • 98
    • 77955792654 scopus 로고    scopus 로고
    • Regulation of homocysteine metabolism and methylation in human and mouse tissues
    • Chen N.C., Yang F., Capecci L.M., Gu Z., Schafer A.I., Durante W., et al. Regulation of homocysteine metabolism and methylation in human and mouse tissues. FASEB J 2010, 24(8):2804-2817.
    • (2010) FASEB J , vol.24 , Issue.8 , pp. 2804-2817
    • Chen, N.C.1    Yang, F.2    Capecci, L.M.3    Gu, Z.4    Schafer, A.I.5    Durante, W.6
  • 99
    • 34548713433 scopus 로고    scopus 로고
    • Hyperhomocysteinemia-mediated DNA hypomethylation and its potential epigenetic role in rats
    • Jiang Y., Sun T., Xiong J., Cao J., Li G., Wang S. Hyperhomocysteinemia-mediated DNA hypomethylation and its potential epigenetic role in rats. Acta Biochim Biophys Sin (Shanghai) 2007, 39(9):657-667.
    • (2007) Acta Biochim Biophys Sin (Shanghai) , vol.39 , Issue.9 , pp. 657-667
    • Jiang, Y.1    Sun, T.2    Xiong, J.3    Cao, J.4    Li, G.5    Wang, S.6
  • 100
    • 58749107929 scopus 로고    scopus 로고
    • Effect of folate deficiency on placental DNA methylation in hyperhomocysteinemic rats
    • Kim J.M., Hong K., Lee J.H., Lee S., Chang N. Effect of folate deficiency on placental DNA methylation in hyperhomocysteinemic rats. J Nutr Biochem 2009, 20(3):172-176.
    • (2009) J Nutr Biochem , vol.20 , Issue.3 , pp. 172-176
    • Kim, J.M.1    Hong, K.2    Lee, J.H.3    Lee, S.4    Chang, N.5
  • 101
    • 77649284559 scopus 로고    scopus 로고
    • Mild folate deficiency induces genetic and epigenetic instability and phenotype changes in prostate cancer cells
    • Bistulfi G., Vandette E., Matsui S., Smiraglia D.J. Mild folate deficiency induces genetic and epigenetic instability and phenotype changes in prostate cancer cells. BMCBiol 2010, 8:6.
    • (2010) BMCBiol , vol.8 , pp. 6
    • Bistulfi, G.1    Vandette, E.2    Matsui, S.3    Smiraglia, D.J.4
  • 102
    • 33646819033 scopus 로고    scopus 로고
    • A folate- and methyl-deficient diet alters the expression of DNA methyltransferases and methyl CpG binding proteins involved in epigenetic gene silencing in livers of F344 rats
    • Ghoshal K., Li X., Datta J., Bai S., Pogribny I., Pogribny M., et al. A folate- and methyl-deficient diet alters the expression of DNA methyltransferases and methyl CpG binding proteins involved in epigenetic gene silencing in livers of F344 rats. J Nutr 2006, 136(6):1522-1527.
    • (2006) J Nutr , vol.136 , Issue.6 , pp. 1522-1527
    • Ghoshal, K.1    Li, X.2    Datta, J.3    Bai, S.4    Pogribny, I.5    Pogribny, M.6
  • 103
    • 48349135395 scopus 로고    scopus 로고
    • Modeling folate, one-carbon metabolism, and DNA methylation
    • Ulrich C.M., Reed M.C., Nijhout H.F. Modeling folate, one-carbon metabolism, and DNA methylation. Nutr Rev 2008, 66(Suppl. 1):S27-S30.
    • (2008) Nutr Rev , vol.66 , Issue.SUPPL. 1
    • Ulrich, C.M.1    Reed, M.C.2    Nijhout, H.F.3
  • 104
    • 33846026708 scopus 로고    scopus 로고
    • Methyl deficiency, alterations in global histone modifications, and carcinogenesis
    • Pogribny I.P., Tryndyak V.P., Muskhelishvili L., Rusyn I., Ross S.A. Methyl deficiency, alterations in global histone modifications, and carcinogenesis. J Nutr 2007, 137(1 Suppl):216S-222S.
    • (2007) J Nutr , vol.137 , Issue.1 SUPPL
    • Pogribny, I.P.1    Tryndyak, V.P.2    Muskhelishvili, L.3    Rusyn, I.4    Ross, S.A.5
  • 105
    • 14744287885 scopus 로고    scopus 로고
    • Polyphenols and prevention of cardiovascular diseases
    • Manach C., Mazur A., Scalbert A. Polyphenols and prevention of cardiovascular diseases. Curr Opin Lipidol 2005, 16(1):77-84.
    • (2005) Curr Opin Lipidol , vol.16 , Issue.1 , pp. 77-84
    • Manach, C.1    Mazur, A.2    Scalbert, A.3
  • 106
    • 33746753353 scopus 로고    scopus 로고
    • Aging and vascular responses to flavanol-rich cocoa
    • Fisher N.D., Hollenberg N.K. Aging and vascular responses to flavanol-rich cocoa. J Hypertens 2006, 24(8):1575-1580.
    • (2006) J Hypertens , vol.24 , Issue.8 , pp. 1575-1580
    • Fisher, N.D.1    Hollenberg, N.K.2
  • 107
    • 13844266915 scopus 로고    scopus 로고
    • Cocoa polyphenols and inflammatory mediators
    • Sies H., Schewe T., Heiss C., Kelm M. Cocoa polyphenols and inflammatory mediators. Am J Clin Nutr 2005, 81(1 Suppl):304S-312S.
    • (2005) Am J Clin Nutr , vol.81 , Issue.1 SUPPL
    • Sies, H.1    Schewe, T.2    Heiss, C.3    Kelm, M.4
  • 108
    • 27744449813 scopus 로고    scopus 로고
    • Acute consumption of flavanol-rich cocoa and the reversal of endothelial dysfunction in smokers
    • Heiss C., Kleinbongard P., Dejam A., Perre S., Schroeter H., Sies H., et al. Acute consumption of flavanol-rich cocoa and the reversal of endothelial dysfunction in smokers. J Am Coll Cardiol 2005, 46(7):1276-1283.
    • (2005) J Am Coll Cardiol , vol.46 , Issue.7 , pp. 1276-1283
    • Heiss, C.1    Kleinbongard, P.2    Dejam, A.3    Perre, S.4    Schroeter, H.5    Sies, H.6
  • 109
    • 33745962138 scopus 로고    scopus 로고
    • Therapeutic potential of resveratrol: the invivo evidence
    • Baur J.A., Sinclair D.A. Therapeutic potential of resveratrol: the invivo evidence. Nat Rev Drug Discov 2006, 5(6):493-506.
    • (2006) Nat Rev Drug Discov , vol.5 , Issue.6 , pp. 493-506
    • Baur, J.A.1    Sinclair, D.A.2
  • 110
    • 74949098826 scopus 로고    scopus 로고
    • Grapes, wines, resveratrol, and heart health
    • Bertelli A.A., Das D.K. Grapes, wines, resveratrol, and heart health. J Cardiovasc Pharmacol 2009, 54(6):468-476.
    • (2009) J Cardiovasc Pharmacol , vol.54 , Issue.6 , pp. 468-476
    • Bertelli, A.A.1    Das, D.K.2
  • 113
    • 34047258298 scopus 로고    scopus 로고
    • Dietary protein restriction of pregnant rats in the F0 generation induces altered methylation of hepatic gene promoters in the adult male offspring in the F1 and F2 generations
    • Burdge G.C., Slater-Jefferies J., Torrens C., Phillips E.S., Hanson M.A., Lillycrop K.A. Dietary protein restriction of pregnant rats in the F0 generation induces altered methylation of hepatic gene promoters in the adult male offspring in the F1 and F2 generations. Br J Nutr 2007, 97(3):435-439.
    • (2007) Br J Nutr , vol.97 , Issue.3 , pp. 435-439
    • Burdge, G.C.1    Slater-Jefferies, J.2    Torrens, C.3    Phillips, E.S.4    Hanson, M.A.5    Lillycrop, K.A.6
  • 114
    • 20444411948 scopus 로고    scopus 로고
    • Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring
    • Lillycrop K.A., Phillips E.S., Jackson A.A., Hanson M.A., Burdge G.C. Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring. J Nutr 2005, 135(6):1382-1386.
    • (2005) J Nutr , vol.135 , Issue.6 , pp. 1382-1386
    • Lillycrop, K.A.1    Phillips, E.S.2    Jackson, A.A.3    Hanson, M.A.4    Burdge, G.C.5
  • 115
    • 34548644772 scopus 로고    scopus 로고
    • The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing
    • De Santa F., Totaro M.G., Prosperini E., Notarbartolo S., Testa G., Natoli G. The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing. Cell 2007, 130(6):1083-1094.
    • (2007) Cell , vol.130 , Issue.6 , pp. 1083-1094
    • De Santa, F.1    Totaro, M.G.2    Prosperini, E.3    Notarbartolo, S.4    Testa, G.5    Natoli, G.6
  • 116
    • 64749111074 scopus 로고    scopus 로고
    • Role of Jhdm2a in regulating metabolic gene expression and obesity resistance
    • Tateishi K., Okada Y., Kallin E.M., Zhang Y. Role of Jhdm2a in regulating metabolic gene expression and obesity resistance. Nature 2009, 458(7239):757-761.
    • (2009) Nature , vol.458 , Issue.7239 , pp. 757-761
    • Tateishi, K.1    Okada, Y.2    Kallin, E.M.3    Zhang, Y.4
  • 117
    • 53249108053 scopus 로고    scopus 로고
    • Role of the lysine-specific demethylase 1 in the proinflammatory phenotype of vascular smooth muscle cells of diabetic mice
    • Reddy M.A., Villeneuve L.M., Wang M., Lanting L., Natarajan R. Role of the lysine-specific demethylase 1 in the proinflammatory phenotype of vascular smooth muscle cells of diabetic mice. Circ Res 2008, 103(6):615-623.
    • (2008) Circ Res , vol.103 , Issue.6 , pp. 615-623
    • Reddy, M.A.1    Villeneuve, L.M.2    Wang, M.3    Lanting, L.4    Natarajan, R.5
  • 118
    • 65549170303 scopus 로고    scopus 로고
    • Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail
    • Brasacchio D., Okabe J., Tikellis C., Balcerczyk A., George P., Baker E.K., et al. Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail. Diabetes 2009, 58(5):1229-1236.
    • (2009) Diabetes , vol.58 , Issue.5 , pp. 1229-1236
    • Brasacchio, D.1    Okabe, J.2    Tikellis, C.3    Balcerczyk, A.4    George, P.5    Baker, E.K.6
  • 119
    • 53349101264 scopus 로고    scopus 로고
    • Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia
    • El-Osta A., Brasacchio D., Yao D., Pocai A., Jones P.L., Roeder R.G., et al. Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia. J Exp Med 2008, 205(10):2409-2417.
    • (2008) J Exp Med , vol.205 , Issue.10 , pp. 2409-2417
    • El-Osta, A.1    Brasacchio, D.2    Yao, D.3    Pocai, A.4    Jones, P.L.5    Roeder, R.G.6
  • 120
    • 77955490964 scopus 로고    scopus 로고
    • Nutritional developmental epigenomics: immediate and long-lasting effects
    • Attig L., Gabory A., Junien C. Nutritional developmental epigenomics: immediate and long-lasting effects. Proc Nutr Soc 2010, 69(2):221-231.
    • (2010) Proc Nutr Soc , vol.69 , Issue.2 , pp. 221-231
    • Attig, L.1    Gabory, A.2    Junien, C.3
  • 121
    • 21344442830 scopus 로고    scopus 로고
    • Nutritional epigenomics of metabolic syndrome: new perspective against the epidemic
    • Gallou-Kabani C., Junien C. Nutritional epigenomics of metabolic syndrome: new perspective against the epidemic. Diabetes 2005, 54(7):1899-1906.
    • (2005) Diabetes , vol.54 , Issue.7 , pp. 1899-1906
    • Gallou-Kabani, C.1    Junien, C.2
  • 122
    • 58149149361 scopus 로고    scopus 로고
    • Effects of neonatal dexamethasone treatment on the cardiovascular stress response of children at school age
    • Karemaker R., Karemaker J.M., Kavelaars A., Tersteeg-Kamperman M., Baerts W., Veen S., et al. Effects of neonatal dexamethasone treatment on the cardiovascular stress response of children at school age. Pediatrics 2008, 122(5):978-987.
    • (2008) Pediatrics , vol.122 , Issue.5 , pp. 978-987
    • Karemaker, R.1    Karemaker, J.M.2    Kavelaars, A.3    Tersteeg-Kamperman, M.4    Baerts, W.5    Veen, S.6
  • 123
    • 69149087790 scopus 로고    scopus 로고
    • Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density
    • Barres R., Osler M.E., Yan J., Rune A., Fritz T., Caidahl K., et al. Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density. Cell Metabolism 2009, 10(3):189-198.
    • (2009) Cell Metabolism , vol.10 , Issue.3 , pp. 189-198
    • Barres, R.1    Osler, M.E.2    Yan, J.3    Rune, A.4    Fritz, T.5    Caidahl, K.6
  • 124
    • 77954601343 scopus 로고    scopus 로고
    • Epigenetic malprogramming of the insulin receptor promoter due to developmental overfeeding
    • Plagemann A., Roepke K., Harder T., Brunn M., Harder A., Wittrock-Staar M., et al. Epigenetic malprogramming of the insulin receptor promoter due to developmental overfeeding. J Perinat Med 2010, 38(4):393-400.
    • (2010) J Perinat Med , vol.38 , Issue.4 , pp. 393-400
    • Plagemann, A.1    Roepke, K.2    Harder, T.3    Brunn, M.4    Harder, A.5    Wittrock-Staar, M.6
  • 125
    • 70350674919 scopus 로고    scopus 로고
    • Hypothalamic proopiomelanocortin promoter methylation becomes altered by early overfeeding: an epigenetic model of obesity and the metabolic syndrome
    • Plagemann A., Harder T., Brunn M., Harder A., Roepke K., Wittrock-Staar M., et al. Hypothalamic proopiomelanocortin promoter methylation becomes altered by early overfeeding: an epigenetic model of obesity and the metabolic syndrome. J Physiol 2009, 587(Pt 20):4963-4976.
    • (2009) J Physiol , vol.587 , Issue.PART 20 , pp. 4963-4976
    • Plagemann, A.1    Harder, T.2    Brunn, M.3    Harder, A.4    Roepke, K.5    Wittrock-Staar, M.6
  • 126
    • 67649448941 scopus 로고    scopus 로고
    • Nutrition in early life, and risk of cancer and metabolic disease: alternative endings in an epigenetic tale?
    • Burdge G.C., Lillycrop K.A., Jackson A.A. Nutrition in early life, and risk of cancer and metabolic disease: alternative endings in an epigenetic tale?. Br J Nutr 2009, 101(5):619-630.
    • (2009) Br J Nutr , vol.101 , Issue.5 , pp. 619-630
    • Burdge, G.C.1    Lillycrop, K.A.2    Jackson, A.A.3
  • 127
    • 33847796827 scopus 로고    scopus 로고
    • Timing of dietary estrogenic exposures and breast cancer risk
    • De Assis S., Hilakivi-Clarke L. Timing of dietary estrogenic exposures and breast cancer risk. Ann N Y Acad Sci 2006, 1089:14-35.
    • (2006) Ann N Y Acad Sci , vol.1089 , pp. 14-35
    • De Assis, S.1    Hilakivi-Clarke, L.2
  • 128
    • 52949108784 scopus 로고    scopus 로고
    • Epigenetic and phenotypic changes result from a continuous pre and post natal dietary exposure to phytoestrogens in an experimental population of mice
    • Guerrero-Bosagna C.M., Sabat P., Valdovinos F.S., Valladares L.E., Clark S.J. Epigenetic and phenotypic changes result from a continuous pre and post natal dietary exposure to phytoestrogens in an experimental population of mice. BMC Physiol 2008, 8:17.
    • (2008) BMC Physiol , vol.8 , pp. 17
    • Guerrero-Bosagna, C.M.1    Sabat, P.2    Valdovinos, F.S.3    Valladares, L.E.4    Clark, S.J.5
  • 129
    • 43049124175 scopus 로고    scopus 로고
    • We are what we eat. The link between diet, evolution and non-genetic inheritance
    • Hunter P. We are what we eat. The link between diet, evolution and non-genetic inheritance. EMBO Rep 2008, 9(5):413-415.
    • (2008) EMBO Rep , vol.9 , Issue.5 , pp. 413-415
    • Hunter, P.1
  • 131
    • 51849124035 scopus 로고    scopus 로고
    • Methyl donor supplementation prevents transgenerational amplification of obesity
    • Waterland R.A., Travisano M., Tahiliani K.G., Rached M.T., Mirza S. Methyl donor supplementation prevents transgenerational amplification of obesity. Int J Obes (Lond) 2008, 32(9):1373-1379.
    • (2008) Int J Obes (Lond) , vol.32 , Issue.9 , pp. 1373-1379
    • Waterland, R.A.1    Travisano, M.2    Tahiliani, K.G.3    Rached, M.T.4    Mirza, S.5
  • 132
    • 0347123629 scopus 로고    scopus 로고
    • Early nutrition, epigenetic changes at transposons and imprinted genes, and enhanced susceptibility to adult chronic diseases
    • Waterland R.A., Jirtle R.L. Early nutrition, epigenetic changes at transposons and imprinted genes, and enhanced susceptibility to adult chronic diseases. Nutrition 2004, 20(1):63-68.
    • (2004) Nutrition , vol.20 , Issue.1 , pp. 63-68
    • Waterland, R.A.1    Jirtle, R.L.2
  • 133
    • 44949207656 scopus 로고    scopus 로고
    • Botanicals as epigenetic modulators for mechanisms contributing to development of metabolic syndrome
    • Kirk H., Cefalu W.T., Ribnicky D., Liu Z., Eilertsen K.J. Botanicals as epigenetic modulators for mechanisms contributing to development of metabolic syndrome. Metabolism 2008, 57(7 Suppl. 1):S16-S23.
    • (2008) Metabolism , vol.57 , Issue.7 SUPPL. 1
    • Kirk, H.1    Cefalu, W.T.2    Ribnicky, D.3    Liu, Z.4    Eilertsen, K.J.5
  • 135
    • 42249094716 scopus 로고    scopus 로고
    • Chromatin dynamics during epigenetic reprogramming in the mouse germ line
    • Hajkova P., Ancelin K., Waldmann T., Lacoste N., Lange U.C., Cesari F., et al. Chromatin dynamics during epigenetic reprogramming in the mouse germ line. Nature 2008, 452(7189):877-881.
    • (2008) Nature , vol.452 , Issue.7189 , pp. 877-881
    • Hajkova, P.1    Ancelin, K.2    Waldmann, T.3    Lacoste, N.4    Lange, U.C.5    Cesari, F.6
  • 137
    • 34247619416 scopus 로고    scopus 로고
    • Heritable germline epimutation is not the same as transgenerational epigenetic inheritance
    • author reply 5-6
    • Chong S., Youngson N.A., Whitelaw E. Heritable germline epimutation is not the same as transgenerational epigenetic inheritance. Nat Genet 2007, 39(5):574-575. author reply 5-6.
    • (2007) Nat Genet , vol.39 , Issue.5 , pp. 574-575
    • Chong, S.1    Youngson, N.A.2    Whitelaw, E.3
  • 138
    • 33646481643 scopus 로고    scopus 로고
    • Dynamic Reprogramming of DNA Methylation at an Epigenetically Sensitive Allele in Mice
    • Blewitt M.E., Vickaryous N.K., Paldi A., Koseki H., Whitelaw E. Dynamic Reprogramming of DNA Methylation at an Epigenetically Sensitive Allele in Mice. PLoS Genet 2006, 2(4):e49.
    • (2006) PLoS Genet , vol.2 , Issue.4
    • Blewitt, M.E.1    Vickaryous, N.K.2    Paldi, A.3    Koseki, H.4    Whitelaw, E.5
  • 139
    • 70350500219 scopus 로고    scopus 로고
    • Polycomb group proteins: navigators of lineage pathways led astray in cancer
    • Bracken A.P., Helin K. Polycomb group proteins: navigators of lineage pathways led astray in cancer. Nat Rev Cancer 2009, 9(11):773-784.
    • (2009) Nat Rev Cancer , vol.9 , Issue.11 , pp. 773-784
    • Bracken, A.P.1    Helin, K.2
  • 140
    • 77953198124 scopus 로고    scopus 로고
    • Regulation of microRNAs by Natural Agents: An Emerging Field in Chemoprevention and Chemotherapy Research
    • Li Y., Kong D., Wang Z., Sarkar F.H. Regulation of microRNAs by Natural Agents: An Emerging Field in Chemoprevention and Chemotherapy Research. Pharm Res 2010, 27(6):1027-1041.
    • (2010) Pharm Res , vol.27 , Issue.6 , pp. 1027-1041
    • Li, Y.1    Kong, D.2    Wang, Z.3    Sarkar, F.H.4
  • 141
    • 17444404622 scopus 로고    scopus 로고
    • Hsp90 and environmental impacts on epigenetic states: a model for the trans-generational effects of diethylstibesterol on uterine development and cancer
    • Ruden D.M., Xiao L., Garfinkel M.D., Lu X. Hsp90 and environmental impacts on epigenetic states: a model for the trans-generational effects of diethylstibesterol on uterine development and cancer. Hum Mol Genet 2005, 14(Spec No 1):R149-R155.
    • (2005) Hum Mol Genet , vol.14 , Issue.SPEC NO 1
    • Ruden, D.M.1    Xiao, L.2    Garfinkel, M.D.3    Lu, X.4
  • 142
    • 0037228526 scopus 로고    scopus 로고
    • Evidence for an epigenetic mechanism by which Hsp90 acts as a capacitor for morphological evolution
    • Sollars V., Lu X., Xiao L., Wang X., Garfinkel M.D., Ruden D.M. Evidence for an epigenetic mechanism by which Hsp90 acts as a capacitor for morphological evolution. Nat Genet 2003, 33(1):70-74.
    • (2003) Nat Genet , vol.33 , Issue.1 , pp. 70-74
    • Sollars, V.1    Lu, X.2    Xiao, L.3    Wang, X.4    Garfinkel, M.D.5    Ruden, D.M.6
  • 143
    • 23944433367 scopus 로고    scopus 로고
    • Drosophila nutrigenomics can provide clues to human gene-nutrient interactions
    • Ruden D.M., De Luca M., Garfinkel M.D., Bynum K.L., Lu X. Drosophila nutrigenomics can provide clues to human gene-nutrient interactions. Annu Rev Nutr 2005, 25:499-522.
    • (2005) Annu Rev Nutr , vol.25 , pp. 499-522
    • Ruden, D.M.1    De Luca, M.2    Garfinkel, M.D.3    Bynum, K.L.4    Lu, X.5
  • 144
    • 4143148752 scopus 로고    scopus 로고
    • Soy isoflavone phyto-pharmaceuticals in interleukin-6 affections: multi-purpose nutraceuticals at the crossroad of hormone replacement, anti-cancer and anti-inflammatory therapy
    • Dijsselbloem N., Vanden Berghe W., De Naeyer A., Haegeman G. Soy isoflavone phyto-pharmaceuticals in interleukin-6 affections: multi-purpose nutraceuticals at the crossroad of hormone replacement, anti-cancer and anti-inflammatory therapy. Biochem Pharmacol 2004, 68:1171-1185.
    • (2004) Biochem Pharmacol , vol.68 , pp. 1171-1185
    • Dijsselbloem, N.1    Vanden Berghe, W.2    De Naeyer, A.3    Haegeman, G.4
  • 145
    • 0142166328 scopus 로고    scopus 로고
    • Cancer chemoprevention with dietary phytochemicals
    • Surh Y.J. Cancer chemoprevention with dietary phytochemicals. Nat Rev Cancer 2003, 3(10):768-780.
    • (2003) Nat Rev Cancer , vol.3 , Issue.10 , pp. 768-780
    • Surh, Y.J.1
  • 146
    • 60749125436 scopus 로고    scopus 로고
    • Epidermal homeostasis: a balancing act of stem cells in the skin
    • Blanpain C., Fuchs E. Epidermal homeostasis: a balancing act of stem cells in the skin. Nat Rev Mol Cell Biol 2009, 10(3):207-217.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , Issue.3 , pp. 207-217
    • Blanpain, C.1    Fuchs, E.2
  • 148
    • 53549083542 scopus 로고    scopus 로고
    • Targeting cancer stem cells with phytochemicals
    • Kawasaki B.T., Hurt E.M., Mistree T., Farrar W.L. Targeting cancer stem cells with phytochemicals. Mol Interv 2008, 8(4):174-184.
    • (2008) Mol Interv , vol.8 , Issue.4 , pp. 174-184
    • Kawasaki, B.T.1    Hurt, E.M.2    Mistree, T.3    Farrar, W.L.4
  • 149
    • 34250666186 scopus 로고    scopus 로고
    • Oxidative stress of neural, hematopoietic, and stem cells: protection by natural compounds
    • Shytle R.D., Ehrhart J., Tan J., Vila J., Cole M., Sanberg C.D., et al. Oxidative stress of neural, hematopoietic, and stem cells: protection by natural compounds. Rejuvenation Res 2007, 10(2):173-178.
    • (2007) Rejuvenation Res , vol.10 , Issue.2 , pp. 173-178
    • Shytle, R.D.1    Ehrhart, J.2    Tan, J.3    Vila, J.4    Cole, M.5    Sanberg, C.D.6
  • 151
    • 51649112926 scopus 로고    scopus 로고
    • NF-kappaB pathway inhibitors preferentially inhibit breast cancer stem-like cells
    • Zhou J., Zhang H., Gu P., Bai J., Margolick J.B., Zhang Y. NF-kappaB pathway inhibitors preferentially inhibit breast cancer stem-like cells. Breast Cancer Res Treat 2008, 111(3):419-427.
    • (2008) Breast Cancer Res Treat , vol.111 , Issue.3 , pp. 419-427
    • Zhou, J.1    Zhang, H.2    Gu, P.3    Bai, J.4    Margolick, J.B.5    Zhang, Y.6
  • 152
    • 75849117800 scopus 로고    scopus 로고
    • Inflammation and oncogenesis: a vicious connection
    • Grivennikov S.I., Karin M. Inflammation and oncogenesis: a vicious connection. Curr Opin Genet Dev 2010, 20(1):65-71.
    • (2010) Curr Opin Genet Dev , vol.20 , Issue.1 , pp. 65-71
    • Grivennikov, S.I.1    Karin, M.2
  • 153
    • 68849116474 scopus 로고    scopus 로고
    • Inflammation, a silent killer in cancer is not so silent!
    • Aggarwal B.B. Inflammation, a silent killer in cancer is not so silent!. Curr Opin Pharmacol 2009, 9(4):347-350.
    • (2009) Curr Opin Pharmacol , vol.9 , Issue.4 , pp. 347-350
    • Aggarwal, B.B.1
  • 154
    • 68849108869 scopus 로고    scopus 로고
    • Inflammation and cancer: how friendly is the relationship for cancer patients?
    • Aggarwal B.B., Gehlot P. Inflammation and cancer: how friendly is the relationship for cancer patients?. Curr Opin Pharmacol 2009, 9(4):351-369.
    • (2009) Curr Opin Pharmacol , vol.9 , Issue.4 , pp. 351-369
    • Aggarwal, B.B.1    Gehlot, P.2
  • 156
    • 54949104629 scopus 로고    scopus 로고
    • A review of dietary factors and its influence on DNA methylation in colorectal carcinogenesis
    • Arasaradnam R.P., Commane D.M., Bradburn D., Mathers J.C. A review of dietary factors and its influence on DNA methylation in colorectal carcinogenesis. Epigenetics 2008, 3(4):193-198.
    • (2008) Epigenetics , vol.3 , Issue.4 , pp. 193-198
    • Arasaradnam, R.P.1    Commane, D.M.2    Bradburn, D.3    Mathers, J.C.4
  • 157
    • 50949132079 scopus 로고    scopus 로고
    • Dietary manipulation of histone structure and function
    • Delage B., Dashwood R.H. Dietary manipulation of histone structure and function. Annu Rev Nutr 2008, 28:347-366.
    • (2008) Annu Rev Nutr , vol.28 , pp. 347-366
    • Delage, B.1    Dashwood, R.H.2
  • 158
    • 78049429911 scopus 로고    scopus 로고
    • Cancer chemoprevention by dietary polyphenols: Promising role for epigenetics
    • Link A., Balaguer F., Goel A. Cancer chemoprevention by dietary polyphenols: Promising role for epigenetics. Biochem Pharmacol 2010, 80(12):1771-1792.
    • (2010) Biochem Pharmacol , vol.80 , Issue.12 , pp. 1771-1792
    • Link, A.1    Balaguer, F.2    Goel, A.3
  • 160
    • 56249130451 scopus 로고    scopus 로고
    • Targeting epigenetic mechanisms: potential of natural products in cancer chemoprevention
    • Hauser A.T., Jung M. Targeting epigenetic mechanisms: potential of natural products in cancer chemoprevention. Planta Medica 2008, 74(13):1593-1601.
    • (2008) Planta Medica , vol.74 , Issue.13 , pp. 1593-1601
    • Hauser, A.T.1    Jung, M.2
  • 162
    • 33845969839 scopus 로고    scopus 로고
    • Dietary polyphenols may affect DNA methylation
    • Fang M., Chen D., Yang C.S. Dietary polyphenols may affect DNA methylation. J Nutr 2007, 137(1 Suppl):223S-228S.
    • (2007) J Nutr , vol.137 , Issue.1 SUPPL
    • Fang, M.1    Chen, D.2    Yang, C.S.3
  • 163
    • 33645987615 scopus 로고    scopus 로고
    • Epigenetic control using natural products and synthetic molecules
    • Suzuki T., Miyata N. Epigenetic control using natural products and synthetic molecules. Curr Med Chem 2006, 13(8):935-958.
    • (2006) Curr Med Chem , vol.13 , Issue.8 , pp. 935-958
    • Suzuki, T.1    Miyata, N.2
  • 164
    • 69249235740 scopus 로고    scopus 로고
    • Calorie restriction and the exercise of chromatin
    • Vaquero A., Reinberg D. Calorie restriction and the exercise of chromatin. Genes Dev 2009, 23(16):1849-1869.
    • (2009) Genes Dev , vol.23 , Issue.16 , pp. 1849-1869
    • Vaquero, A.1    Reinberg, D.2
  • 165
    • 84860275721 scopus 로고    scopus 로고
    • Epigenetic impact of dietary polyphenols in cancer chemoprevention: lifelong remodeling of our epigenomes
    • Vanden Berghe W. Epigenetic impact of dietary polyphenols in cancer chemoprevention: lifelong remodeling of our epigenomes. Pharmacol Res 2012, 65(6):565-576.
    • (2012) Pharmacol Res , vol.65 , Issue.6 , pp. 565-576
    • Vanden Berghe, W.1
  • 166
    • 78049440083 scopus 로고    scopus 로고
    • Nature or nurture: let food be your epigenetic medicine in chronic inflammatory disorders
    • Szarc vel Szic K., Ndlovu M.N., Haegeman G., Vanden Berghe W. Nature or nurture: let food be your epigenetic medicine in chronic inflammatory disorders. Biochem Pharmacol 2010, 80(12):1816-1832.
    • (2010) Biochem Pharmacol , vol.80 , Issue.12 , pp. 1816-1832
    • Szarc vel Szic, K.1    Ndlovu, M.N.2    Haegeman, G.3    Vanden Berghe, W.4
  • 168
    • 70350464482 scopus 로고    scopus 로고
    • Hyperactivated NF-{kappa}B and AP-1 transcription factors promote highly accessible chromatin and constitutive transcription across the interleukin-6 gene promoter in metastatic breast cancer cells
    • Ndlovu M.N., Van Lint C., Van Wesemael K., Callebert P., Chalbos D., Haegeman G., et al. Hyperactivated NF-{kappa}B and AP-1 transcription factors promote highly accessible chromatin and constitutive transcription across the interleukin-6 gene promoter in metastatic breast cancer cells. Mol Cell Biol 2009, 29(20):5488-5504.
    • (2009) Mol Cell Biol , vol.29 , Issue.20 , pp. 5488-5504
    • Ndlovu, M.N.1    Van Lint, C.2    Van Wesemael, K.3    Callebert, P.4    Chalbos, D.5    Haegeman, G.6
  • 169
    • 41849146748 scopus 로고    scopus 로고
    • Epigenetic multiple ligands: mixed histone/protein methyltransferase, acetyltransferase, and class III deacetylase (sirtuin) inhibitors
    • Mai A., Cheng D., Bedford M.T., Valente S., Nebbioso A., Perrone A., et al. Epigenetic multiple ligands: mixed histone/protein methyltransferase, acetyltransferase, and class III deacetylase (sirtuin) inhibitors. J Med Chem 2008, 51(7):2279-2290.
    • (2008) J Med Chem , vol.51 , Issue.7 , pp. 2279-2290
    • Mai, A.1    Cheng, D.2    Bedford, M.T.3    Valente, S.4    Nebbioso, A.5    Perrone, A.6
  • 170
    • 45249123900 scopus 로고    scopus 로고
    • The Roles of Dietary PPARgamma Ligands for Metastasis in Colorectal Cancer
    • Kuniyasu H. The Roles of Dietary PPARgamma Ligands for Metastasis in Colorectal Cancer. PPAR research 2008, 2008:529720.
    • (2008) PPAR research , vol.2008 , pp. 529720
    • Kuniyasu, H.1
  • 171
    • 0038768712 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals
    • Denison M.S., Nagy S.R. Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals. Annu Rev Pharmacol Toxicol 2003, 43:309-334.
    • (2003) Annu Rev Pharmacol Toxicol , vol.43 , pp. 309-334
    • Denison, M.S.1    Nagy, S.R.2
  • 172
    • 77951088991 scopus 로고    scopus 로고
    • Environmental oestrogens and breast cancer: evidence for combined involvement of dietary, household and cosmetic xenoestrogens
    • Darbre P.D., Charles A.K. Environmental oestrogens and breast cancer: evidence for combined involvement of dietary, household and cosmetic xenoestrogens. Anticancer Res 2010, 30(3):815-827.
    • (2010) Anticancer Res , vol.30 , Issue.3 , pp. 815-827
    • Darbre, P.D.1    Charles, A.K.2
  • 174
    • 4043089112 scopus 로고    scopus 로고
    • Pharmacokinetics and metabolism of dietary flavonoids in humans
    • Manach C., Donovan J.L. Pharmacokinetics and metabolism of dietary flavonoids in humans. Free Radic Res 2004, 38(8):771-785.
    • (2004) Free Radic Res , vol.38 , Issue.8 , pp. 771-785
    • Manach, C.1    Donovan, J.L.2
  • 175
    • 13844281685 scopus 로고    scopus 로고
    • Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies
    • Manach C., Williamson G., Morand C., Scalbert A., Remesy C. Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies. Am J Clin Nutr 2005, 81(1 Suppl):230S-242S.
    • (2005) Am J Clin Nutr , vol.81 , Issue.1 SUPPL
    • Manach, C.1    Williamson, G.2    Morand, C.3    Scalbert, A.4    Remesy, C.5
  • 177
    • 13844271387 scopus 로고    scopus 로고
    • Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies
    • Williamson G., Manach C. Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies. Am J Clin Nutr 2005, 81(1 Suppl):243S-255S.
    • (2005) Am J Clin Nutr , vol.81 , Issue.1 SUPPL
    • Williamson, G.1    Manach, C.2
  • 178
    • 84864188555 scopus 로고    scopus 로고
    • Redox Mediating Epigenetic Changes Confer Metabolic Memories
    • El-Osta A. Redox Mediating Epigenetic Changes Confer Metabolic Memories. Circ Res 2012, 111(3):262-264.
    • (2012) Circ Res , vol.111 , Issue.3 , pp. 262-264
    • El-Osta, A.1
  • 179
    • 50249091120 scopus 로고    scopus 로고
    • Chemical regulation of epigenetic modifications: opportunities for new cancer therapy
    • Zheng Y.G., Wu J., Chen Z., Goodman M. Chemical regulation of epigenetic modifications: opportunities for new cancer therapy. Med Res Rev 2008, 28(5):645-687.
    • (2008) Med Res Rev , vol.28 , Issue.5 , pp. 645-687
    • Zheng, Y.G.1    Wu, J.2    Chen, Z.3    Goodman, M.4
  • 180
    • 33745813187 scopus 로고    scopus 로고
    • Reading protein modifications with interaction domains
    • Seet B.T., Dikic I., Zhou M.M., Pawson T. Reading protein modifications with interaction domains. Nat Rev Mol Cell Biol 2006, 7(7):473-483.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , Issue.7 , pp. 473-483
    • Seet, B.T.1    Dikic, I.2    Zhou, M.M.3    Pawson, T.4
  • 181
    • 77949351403 scopus 로고    scopus 로고
    • Screening for inhibitors of low-affinity epigenetic peptide-protein interactions: an AlphaScreen-based assay for antagonists of methyl-lysine binding proteins
    • Wigle TJ, Herold JM, Senisterra GA, Vedadi M, Kireev DB, Arrowsmith CH, et al. Screening for inhibitors of low-affinity epigenetic peptide-protein interactions: an AlphaScreen-based assay for antagonists of methyl-lysine binding proteins. J Biomol Screen. 15(1): 62-71.
    • J Biomol Screen , vol.15 , Issue.1 , pp. 62-71
    • Wigle, T.J.1    Herold, J.M.2    Senisterra, G.A.3    Vedadi, M.4    Kireev, D.B.5    Arrowsmith, C.H.6
  • 182
    • 77952547233 scopus 로고    scopus 로고
    • Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases
    • Imai S., Guarente L. Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases. Trends Pharmacol Sci 2010, 31(5):212-220.
    • (2010) Trends Pharmacol Sci , vol.31 , Issue.5 , pp. 212-220
    • Imai, S.1    Guarente, L.2
  • 183
    • 62349110317 scopus 로고    scopus 로고
    • Effects of insulin and glucose on cellular metabolic fluxes in homocysteine transsulfuration, remethylation, S-adenosylmethionine synthesis, and global deoxyribonucleic acid methylation
    • Chiang E.P., Wang Y.C., Chen W.W., Tang F.Y. Effects of insulin and glucose on cellular metabolic fluxes in homocysteine transsulfuration, remethylation, S-adenosylmethionine synthesis, and global deoxyribonucleic acid methylation. J Clin Endocrinol Metab 2009, 94(3):1017-1025.
    • (2009) J Clin Endocrinol Metab , vol.94 , Issue.3 , pp. 1017-1025
    • Chiang, E.P.1    Wang, Y.C.2    Chen, W.W.3    Tang, F.Y.4
  • 184
    • 70449641902 scopus 로고    scopus 로고
    • Hypothesis: a unifying mechanism for nutrition and chemicals as lifelong modulators of DNA hypomethylation
    • Lee D.H., Jacobs D.R., Porta M. Hypothesis: a unifying mechanism for nutrition and chemicals as lifelong modulators of DNA hypomethylation. Environ Health Perspect 2009, 117(12):1799-1802.
    • (2009) Environ Health Perspect , vol.117 , Issue.12 , pp. 1799-1802
    • Lee, D.H.1    Jacobs, D.R.2    Porta, M.3
  • 186
    • 43049095216 scopus 로고    scopus 로고
    • Xenohormesis: Sensing the Chemical Cues of Other Species
    • Howitz K.T., Sinclair D.A. Xenohormesis: Sensing the Chemical Cues of Other Species. Cell 2008, 133(3):387-391.
    • (2008) Cell , vol.133 , Issue.3 , pp. 387-391
    • Howitz, K.T.1    Sinclair, D.A.2
  • 187
    • 33745841186 scopus 로고    scopus 로고
    • Modulating TNF-alpha signaling with natural products
    • Paul A.T., Gohil V.M., Bhutani K.K. Modulating TNF-alpha signaling with natural products. Drug Discov Today 2006, 11(15-16):725-732.
    • (2006) Drug Discov Today , vol.11 , Issue.15-16 , pp. 725-732
    • Paul, A.T.1    Gohil, V.M.2    Bhutani, K.K.3
  • 188
    • 65649109750 scopus 로고    scopus 로고
    • Inhibition of transcription factors by plant-derived compounds and their implications in inflammation and cancer
    • Rios J.L., Recio M.C., Escandell J.M., Andujar I. Inhibition of transcription factors by plant-derived compounds and their implications in inflammation and cancer. Curr Pharm Des 2009, 15(11):1212-1237.
    • (2009) Curr Pharm Des , vol.15 , Issue.11 , pp. 1212-1237
    • Rios, J.L.1    Recio, M.C.2    Escandell, J.M.3    Andujar, I.4
  • 189
    • 36049051459 scopus 로고    scopus 로고
    • Back to basics: how natural products can provide the basis for new therapeutics
    • Deorukhkar A., Krishnan S., Sethi G., Aggarwal B.B. Back to basics: how natural products can provide the basis for new therapeutics. Expert Opin Investig Drugs 2007, 16(11):1753-1773.
    • (2007) Expert Opin Investig Drugs , vol.16 , Issue.11 , pp. 1753-1773
    • Deorukhkar, A.1    Krishnan, S.2    Sethi, G.3    Aggarwal, B.B.4
  • 191
    • 0036217821 scopus 로고    scopus 로고
    • Natural products as targeted modulators of the nuclear factor-kappaB pathway
    • Bremner P., Heinrich M. Natural products as targeted modulators of the nuclear factor-kappaB pathway. J Pharm Pharmacol 2002, 54(4):453-472.
    • (2002) J Pharm Pharmacol , vol.54 , Issue.4 , pp. 453-472
    • Bremner, P.1    Heinrich, M.2
  • 192
    • 0346505340 scopus 로고    scopus 로고
    • The IKK NF-kappa B system: a treasure trove for drug development
    • Karin M., Yamamoto Y., Wang Q.M. The IKK NF-kappa B system: a treasure trove for drug development. Nat Rev Drug Discov 2004, 3(1):17-26.
    • (2004) Nat Rev Drug Discov , vol.3 , Issue.1 , pp. 17-26
    • Karin, M.1    Yamamoto, Y.2    Wang, Q.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.