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Volumn 29, Issue 1, 2014, Pages 86-92

Hematopoietic stem cell aging

Author keywords

[No Author keywords available]

Indexed keywords

FIBRINOGEN RECEPTOR; NOTCH RECEPTOR; PROTEIN CDC42; RANTES; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SIRTUIN; SIRTUIN 3; WNT PROTEIN; WNT5A PROTEIN;

EID: 84901757966     PISSN: 09527915     EISSN: 18790372     Source Type: Journal    
DOI: 10.1016/j.coi.2014.05.002     Document Type: Review
Times cited : (51)

References (78)
  • 1
    • 29844444409 scopus 로고    scopus 로고
    • Issues of aging and geriatric medicine: relevance to cancer treatment and hematopoietic reconstitution
    • Ershler W.B., Artz A.S., Keller E.T. Issues of aging and geriatric medicine: relevance to cancer treatment and hematopoietic reconstitution. Biol Blood Marrow Transplant 2006, 12:100-106.
    • (2006) Biol Blood Marrow Transplant , vol.12 , pp. 100-106
    • Ershler, W.B.1    Artz, A.S.2    Keller, E.T.3
  • 3
    • 0034718599 scopus 로고    scopus 로고
    • Enrichment for murine keratinocyte stem cells based on cell surface phenotype
    • Tani H., Morris R.J., Kaur P. Enrichment for murine keratinocyte stem cells based on cell surface phenotype. Proc Natl Acad Sci U S A 2000, 97:10960-10965.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 10960-10965
    • Tani, H.1    Morris, R.J.2    Kaur, P.3
  • 4
    • 0034614379 scopus 로고    scopus 로고
    • Stem cells: a new lease on life
    • Fuchs E., Segre J.A. Stem cells: a new lease on life. Cell 2000, 100:143-155.
    • (2000) Cell , vol.100 , pp. 143-155
    • Fuchs, E.1    Segre, J.A.2
  • 6
    • 0037417893 scopus 로고    scopus 로고
    • Molecular features of adult mouse small intestinal epithelial progenitors
    • Stappenbeck T.S., Mills J.C., Gordon J.I. Molecular features of adult mouse small intestinal epithelial progenitors. Proc Natl Acad Sci U S A 2003, 100:1004-1009.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 1004-1009
    • Stappenbeck, T.S.1    Mills, J.C.2    Gordon, J.I.3
  • 7
    • 0041666387 scopus 로고    scopus 로고
    • The role of stem cells in aging
    • Van Zant G., Liang Y. The role of stem cells in aging. Exp Hematol 2003, 31:659-672.
    • (2003) Exp Hematol , vol.31 , pp. 659-672
    • Van Zant, G.1    Liang, Y.2
  • 8
    • 0036230333 scopus 로고    scopus 로고
    • The aging of lympho-hematopoietic stem cells
    • Geiger H., Van Zant G. The aging of lympho-hematopoietic stem cells. Nat Immunol 2002, 3:329-333.
    • (2002) Nat Immunol , vol.3 , pp. 329-333
    • Geiger, H.1    Van Zant, G.2
  • 9
    • 13944261231 scopus 로고    scopus 로고
    • Rejuvenation of aged progenitor cells by exposure to a young systemic environment
    • Conboy I.M., Conboy M.J., Wagers A.J., Girma E.R., Weissman I.L., Rando T.A. Rejuvenation of aged progenitor cells by exposure to a young systemic environment. Nature 2005, 433:760-764.
    • (2005) Nature , vol.433 , pp. 760-764
    • Conboy, I.M.1    Conboy, M.J.2    Wagers, A.J.3    Girma, E.R.4    Weissman, I.L.5    Rando, T.A.6
  • 10
    • 9644274090 scopus 로고    scopus 로고
    • Intrinsic ageing of gut epithelial stem cells
    • Kirkwood T.B. Intrinsic ageing of gut epithelial stem cells. Mech Ageing Dev 2004, 125:911-915.
    • (2004) Mech Ageing Dev , vol.125 , pp. 911-915
    • Kirkwood, T.B.1
  • 11
    • 0035234581 scopus 로고    scopus 로고
    • Ageing of murine small intestinal stem cells
    • 66-79; discussion 79-84
    • Potten C.S., Martin K., Kirkwood T.B. Ageing of murine small intestinal stem cells. Novartis Found Symp 2001, 235:101-104. 66-79; discussion 79-84.
    • (2001) Novartis Found Symp , vol.235 , pp. 101-104
    • Potten, C.S.1    Martin, K.2    Kirkwood, T.B.3
  • 12
    • 0038806560 scopus 로고    scopus 로고
    • Major age-related changes of mouse hematopoietic stem/progenitor cells
    • Kim M., Moon H.B., Spangrude G.J. Major age-related changes of mouse hematopoietic stem/progenitor cells. Ann N Y Acad Sci 2003, 996:195-208.
    • (2003) Ann N Y Acad Sci , vol.996 , pp. 195-208
    • Kim, M.1    Moon, H.B.2    Spangrude, G.J.3
  • 13
    • 0034613690 scopus 로고    scopus 로고
    • Age-associated characteristics of murine hematopoietic stem cells
    • [record as supplied by publisher]
    • Sudo K., Ema H., Morita Y., Nakauchi H. Age-associated characteristics of murine hematopoietic stem cells. J Exp Med 2000, 192:1273-1280. [record as supplied by publisher].
    • (2000) J Exp Med , vol.192 , pp. 1273-1280
    • Sudo, K.1    Ema, H.2    Morita, Y.3    Nakauchi, H.4
  • 15
    • 85047689866 scopus 로고    scopus 로고
    • Telomeres, stem cells, senescence, and cancer
    • Sharpless N.E., DePinho R.A. Telomeres, stem cells, senescence, and cancer. J Clin Invest 2004, 113:160-168.
    • (2004) J Clin Invest , vol.113 , pp. 160-168
    • Sharpless, N.E.1    DePinho, R.A.2
  • 17
    • 17044426724 scopus 로고    scopus 로고
    • Regulation of hematopoietic stem cell aging in vivo by a distinct genetic element
    • Geiger H., Rennebeck G., Van Zant G. Regulation of hematopoietic stem cell aging in vivo by a distinct genetic element. Proc Natl Acad Sci U S A 2005, 102:5102-5110.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 5102-5110
    • Geiger, H.1    Rennebeck, G.2    Van Zant, G.3
  • 19
    • 34250017413 scopus 로고    scopus 로고
    • Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftment
    • Ju Z., Jiang H., Jaworski M., Rathinam C., Gompf A., Klein C., Trumpp A., Rudolph K.L. Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftment. Nat Med 2007, 13:742-747.
    • (2007) Nat Med , vol.13 , pp. 742-747
    • Ju, Z.1    Jiang, H.2    Jaworski, M.3    Rathinam, C.4    Gompf, A.5    Klein, C.6    Trumpp, A.7    Rudolph, K.L.8
  • 20
    • 33745614062 scopus 로고    scopus 로고
    • Stem cells, ageing and the quest for immortality
    • Rando T.A. Stem cells, ageing and the quest for immortality. Nature 2006, 441:1080-1090.
    • (2006) Nature , vol.441 , pp. 1080-1090
    • Rando, T.A.1
  • 21
    • 75749090492 scopus 로고    scopus 로고
    • Systemic signals regulate ageing and rejuvenation of blood stem cell niches
    • Mayack S.R., Shadrach J.L., Kim F.S., Wagers A.J. Systemic signals regulate ageing and rejuvenation of blood stem cell niches. Nature 2010, 463:495-500.
    • (2010) Nature , vol.463 , pp. 495-500
    • Mayack, S.R.1    Shadrach, J.L.2    Kim, F.S.3    Wagers, A.J.4
  • 22
    • 67649402297 scopus 로고    scopus 로고
    • Aging in the lympho-hematopoietic stem cell compartment
    • Geiger H., Rudolph K.L. Aging in the lympho-hematopoietic stem cell compartment. Trends Immunol 2009, 30:360-365.
    • (2009) Trends Immunol , vol.30 , pp. 360-365
    • Geiger, H.1    Rudolph, K.L.2
  • 25
    • 0034008968 scopus 로고    scopus 로고
    • Genetic regulation of primitive hematopoietic stem cell senescence
    • Chen J., Astle C.M., Harrison D.E. Genetic regulation of primitive hematopoietic stem cell senescence. Exp Hematol 2000, 28:442-450.
    • (2000) Exp Hematol , vol.28 , pp. 442-450
    • Chen, J.1    Astle, C.M.2    Harrison, D.E.3
  • 26
    • 23744439044 scopus 로고    scopus 로고
    • Effects of aging on the homing and engraftment of murine hematopoietic stem and progenitor cells
    • Liang Y., Van Zant G., Szilvassy S.J. Effects of aging on the homing and engraftment of murine hematopoietic stem and progenitor cells. Blood 2005, 106:1479-1480.
    • (2005) Blood , vol.106 , pp. 1479-1480
    • Liang, Y.1    Van Zant, G.2    Szilvassy, S.J.3
  • 27
    • 33644781621 scopus 로고    scopus 로고
    • The hematopoietic stem compartment consists of a limited number of discrete stem cell subsets
    • Sieburg H.B., Cho R.H., Dykstra B., Uchida N., Eaves C.J., Muller-Sieburg C.E. The hematopoietic stem compartment consists of a limited number of discrete stem cell subsets. Blood 2006, 107:2311-2320.
    • (2006) Blood , vol.107 , pp. 2311-2320
    • Sieburg, H.B.1    Cho, R.H.2    Dykstra, B.3    Uchida, N.4    Eaves, C.J.5    Muller-Sieburg, C.E.6
  • 28
    • 0037103312 scopus 로고    scopus 로고
    • Deterministic regulation of hematopoietic stem cell self-renewal and differentiation
    • Muller-Sieburg C.E., Cho R.H., Thoman M., Adkins B., Sieburg H.B. Deterministic regulation of hematopoietic stem cell self-renewal and differentiation. Blood 2002, 100:1302-1310.
    • (2002) Blood , vol.100 , pp. 1302-1310
    • Muller-Sieburg, C.E.1    Cho, R.H.2    Thoman, M.3    Adkins, B.4    Sieburg, H.B.5
  • 30
    • 84857873445 scopus 로고    scopus 로고
    • Hematopoietic stem cell subtypes expand differentially during development and display distinct lymphopoietic programs
    • Benz C., Copley M.R., Kent D.G., Wohrer S., Cortes A., Aghaeepour N., Ma E., Mader H., Rowe K., Day C., et al. Hematopoietic stem cell subtypes expand differentially during development and display distinct lymphopoietic programs. Cell Stem Cell 2012, 10:273-283.
    • (2012) Cell Stem Cell , vol.10 , pp. 273-283
    • Benz, C.1    Copley, M.R.2    Kent, D.G.3    Wohrer, S.4    Cortes, A.5    Aghaeepour, N.6    Ma, E.7    Mader, H.8    Rowe, K.9    Day, C.10
  • 31
    • 77953512588 scopus 로고    scopus 로고
    • Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment
    • Morita Y., Ema H., Nakauchi H. Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment. J Exp Med 2010, 207:1173-1180.
    • (2010) J Exp Med , vol.207 , pp. 1173-1180
    • Morita, Y.1    Ema, H.2    Nakauchi, H.3
  • 32
    • 8444238550 scopus 로고    scopus 로고
    • Classification of short kinetics by shape
    • Sieburg H.B., Muller-Sieburg C.E. Classification of short kinetics by shape. In Silico Biol 2004, 4:209-217.
    • (2004) In Silico Biol , vol.4 , pp. 209-217
    • Sieburg, H.B.1    Muller-Sieburg, C.E.2
  • 33
    • 77950418688 scopus 로고    scopus 로고
    • Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion
    • Beerman I., Bhattacharya D., Zandi S., Sigvardsson M., Weissman I.L., Bryder D., Rossi D.J. Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion. Proc Natl Acad Sci U S A 2010, 107:5465-5470.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 5465-5470
    • Beerman, I.1    Bhattacharya, D.2    Zandi, S.3    Sigvardsson, M.4    Weissman, I.L.5    Bryder, D.6    Rossi, D.J.7
  • 34
    • 77449145533 scopus 로고    scopus 로고
    • Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1
    • Challen G.A., Boles N.C., Chambers S.M., Goodell M.A. Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1. Cell Stem Cell 2010, 6:265-278.
    • (2010) Cell Stem Cell , vol.6 , pp. 265-278
    • Challen, G.A.1    Boles, N.C.2    Chambers, S.M.3    Goodell, M.A.4
  • 35
    • 84855507486 scopus 로고    scopus 로고
    • Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cells
    • Dykstra B., Olthof S., Schreuder J., Ritsema M., de Haan G. Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cells. J Exp Med 2011, 208:2691-2700.
    • (2011) J Exp Med , vol.208 , pp. 2691-2700
    • Dykstra, B.1    Olthof, S.2    Schreuder, J.3    Ritsema, M.4    de Haan, G.5
  • 36
    • 84880790360 scopus 로고    scopus 로고
    • CD41 expression marks myeloid-biased adult hematopoietic stem cells and increases with age
    • Gekas C., Graf T. CD41 expression marks myeloid-biased adult hematopoietic stem cells and increases with age. Blood 2013, 121:4463-4472.
    • (2013) Blood , vol.121 , pp. 4463-4472
    • Gekas, C.1    Graf, T.2
  • 37
    • 47049099198 scopus 로고    scopus 로고
    • A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cells
    • Cho R.H., Sieburg H.B., Muller-Sieburg C.E. A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cells. Blood 2008, 111:5553-5561.
    • (2008) Blood , vol.111 , pp. 5553-5561
    • Cho, R.H.1    Sieburg, H.B.2    Muller-Sieburg, C.E.3
  • 39
    • 34247466995 scopus 로고    scopus 로고
    • Stem cells, aging, niche, adhesion and Cdc42: a model for changes in cell-cell interactions and hematopoietic stem cell aging
    • Geiger H., Koehler A., Gunzer M. Stem cells, aging, niche, adhesion and Cdc42: a model for changes in cell-cell interactions and hematopoietic stem cell aging. Cell Cycle 2007, 6.
    • (2007) Cell Cycle , pp. 6
    • Geiger, H.1    Koehler, A.2    Gunzer, M.3
  • 40
    • 67651098996 scopus 로고    scopus 로고
    • Altered cellular dynamics and endosteal location of aged early hematopoietic progenitor cells revealed by time-lapse intravital imaging in long bones
    • Kohler A., Schmithorst V., Filippi M.D., Ryan M.A., Daria D., Gunzer M., Geiger H. Altered cellular dynamics and endosteal location of aged early hematopoietic progenitor cells revealed by time-lapse intravital imaging in long bones. Blood 2009, 114:290-298.
    • (2009) Blood , vol.114 , pp. 290-298
    • Kohler, A.1    Schmithorst, V.2    Filippi, M.D.3    Ryan, M.A.4    Daria, D.5    Gunzer, M.6    Geiger, H.7
  • 43
    • 34250007142 scopus 로고    scopus 로고
    • Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age
    • Rossi D.J., Bryder D., Seita J., Nussenzweig A., Hoeijmakers J., Weissman I.L. Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. Nature 2007, 447:725-729.
    • (2007) Nature , vol.447 , pp. 725-729
    • Rossi, D.J.1    Bryder, D.2    Seita, J.3    Nussenzweig, A.4    Hoeijmakers, J.5    Weissman, I.L.6
  • 44
    • 84864648787 scopus 로고    scopus 로고
    • Aging of the microenvironment influences clonality in hematopoiesis
    • Vas V., Senger K., Dorr K., Niebel A., Geiger H. Aging of the microenvironment influences clonality in hematopoiesis. PLoS ONE 2012, 7:e42080.
    • (2012) PLoS ONE , vol.7
    • Vas, V.1    Senger, K.2    Dorr, K.3    Niebel, A.4    Geiger, H.5
  • 45
    • 84857390987 scopus 로고    scopus 로고
    • Contribution of an aged microenvironment to aging-associated myeloproliferative disease
    • Vas V., Wandhoff C., Dorr K., Niebel A., Geiger H. Contribution of an aged microenvironment to aging-associated myeloproliferative disease. PLoS ONE 2012, 7:e31523.
    • (2012) PLoS ONE , vol.7
    • Vas, V.1    Wandhoff, C.2    Dorr, K.3    Niebel, A.4    Geiger, H.5
  • 46
    • 84858649330 scopus 로고    scopus 로고
    • Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing
    • Ergen A.V., Boles N.C., Goodell M.A. Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing. Blood 2012, 119:2500-2509.
    • (2012) Blood , vol.119 , pp. 2500-2509
    • Ergen, A.V.1    Boles, N.C.2    Goodell, M.A.3
  • 49
    • 58049203043 scopus 로고    scopus 로고
    • Wnt-related molecules and signaling pathway equilibrium in hematopoiesis
    • Malhotra S., Kincade P.W. Wnt-related molecules and signaling pathway equilibrium in hematopoiesis. Cell Stem Cell 2009, 4:27-36.
    • (2009) Cell Stem Cell , vol.4 , pp. 27-36
    • Malhotra, S.1    Kincade, P.W.2
  • 50
    • 34547604466 scopus 로고    scopus 로고
    • Cdc42 and noncanonical Wnt signal transduction pathways cooperate to promote cell polarity
    • Schlessinger K., McManus E.J., Hall A. Cdc42 and noncanonical Wnt signal transduction pathways cooperate to promote cell polarity. J Cell Biol 2007, 178:355-361.
    • (2007) J Cell Biol , vol.178 , pp. 355-361
    • Schlessinger, K.1    McManus, E.J.2    Hall, A.3
  • 51
    • 39749147015 scopus 로고    scopus 로고
    • From individual Wnt pathways towards a Wnt signalling network
    • Kestler H.A., Kuhl M. From individual Wnt pathways towards a Wnt signalling network. Philos Trans R Soc Lond B Biol Sci 2008, 363:1333-1347.
    • (2008) Philos Trans R Soc Lond B Biol Sci , vol.363 , pp. 1333-1347
    • Kestler, H.A.1    Kuhl, M.2
  • 53
    • 84879591586 scopus 로고    scopus 로고
    • Sirt1 ablation promotes stress-induced loss of epigenetic and genomic hematopoietic stem and progenitor cell maintenance
    • Singh S.K., Williams C.A., Klarmann K., Burkett S.S., Keller J.R., Oberdoerffer P. Sirt1 ablation promotes stress-induced loss of epigenetic and genomic hematopoietic stem and progenitor cell maintenance. J Exp Med 2013, 210:987-1001.
    • (2013) J Exp Med , vol.210 , pp. 987-1001
    • Singh, S.K.1    Williams, C.A.2    Klarmann, K.3    Burkett, S.S.4    Keller, J.R.5    Oberdoerffer, P.6
  • 57
    • 34548852838 scopus 로고    scopus 로고
    • Age-related defects in B lymphopoiesis underlie the myeloid dominance of adult leukemia
    • Signer R.A., Montecino-Rodriguez E., Witte O.N., McLaughlin J., Dorshkind K. Age-related defects in B lymphopoiesis underlie the myeloid dominance of adult leukemia. Blood 2007, 110:1831-1839.
    • (2007) Blood , vol.110 , pp. 1831-1839
    • Signer, R.A.1    Montecino-Rodriguez, E.2    Witte, O.N.3    McLaughlin, J.4    Dorshkind, K.5
  • 58
    • 56549120340 scopus 로고    scopus 로고
    • Aging and cancer resistance in lymphoid progenitors are linked processes conferred by p16Ink4a and Arf
    • Signer R.A., Montecino-Rodriguez E., Witte O.N., Dorshkind K. Aging and cancer resistance in lymphoid progenitors are linked processes conferred by p16Ink4a and Arf. Genes Dev 2008, 22:3115-3120.
    • (2008) Genes Dev , vol.22 , pp. 3115-3120
    • Signer, R.A.1    Montecino-Rodriguez, E.2    Witte, O.N.3    Dorshkind, K.4
  • 59
    • 36549083391 scopus 로고    scopus 로고
    • Declining cellular fitness with age promotes cancer initiation by selecting for adaptive oncogenic mutations
    • Marusyk A., Degregori J. Declining cellular fitness with age promotes cancer initiation by selecting for adaptive oncogenic mutations. Biochim Biophys Acta 2008, 1785:1-11.
    • (2008) Biochim Biophys Acta , vol.1785 , pp. 1-11
    • Marusyk, A.1    Degregori, J.2
  • 61
    • 80055110647 scopus 로고    scopus 로고
    • Aging-associated changes in hematopoiesis and leukemogenesis: what's the connection?
    • Henry C.J., Marusyk A., DeGregori J. Aging-associated changes in hematopoiesis and leukemogenesis: what's the connection?. Aging (Albany NY) 2011, 3:643-656.
    • (2011) Aging (Albany NY) , vol.3 , pp. 643-656
    • Henry, C.J.1    Marusyk, A.2    DeGregori, J.3
  • 62
    • 84866726837 scopus 로고    scopus 로고
    • Understanding the immune response to seasonal influenza vaccination in older adults: a systems biology approach
    • Lambert N.D., Ovsyannikova I.G., Pankratz V.S., Jacobson R.M., Poland G.A. Understanding the immune response to seasonal influenza vaccination in older adults: a systems biology approach. Expert Rev Vaccines 2012, 11:985-994.
    • (2012) Expert Rev Vaccines , vol.11 , pp. 985-994
    • Lambert, N.D.1    Ovsyannikova, I.G.2    Pankratz, V.S.3    Jacobson, R.M.4    Poland, G.A.5
  • 63
    • 24044463890 scopus 로고    scopus 로고
    • Dysregulation of T-cell function in the elderly: scientific basis and clinical implications
    • Fulop T., Larbi A., Wikby A., Mocchegiani E., Hirokawa K., Pawelec G. Dysregulation of T-cell function in the elderly: scientific basis and clinical implications. Drugs Aging 2005, 22:589-603.
    • (2005) Drugs Aging , vol.22 , pp. 589-603
    • Fulop, T.1    Larbi, A.2    Wikby, A.3    Mocchegiani, E.4    Hirokawa, K.5    Pawelec, G.6
  • 65
    • 0344827208 scopus 로고    scopus 로고
    • Notch-mediated restoration of regenerative potential to aged muscle
    • Conboy I.M., Conboy M.J., Smythe G.M., Rando T.A. Notch-mediated restoration of regenerative potential to aged muscle. Science 2003, 302:1575-1580.
    • (2003) Science , vol.302 , pp. 1575-1580
    • Conboy, I.M.1    Conboy, M.J.2    Smythe, G.M.3    Rando, T.A.4
  • 66
    • 34547924424 scopus 로고    scopus 로고
    • Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis
    • Brack A.S., Conboy M.J., Roy S., Lee M., Kuo C.J., Keller C., Rando T.A. Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis. Science 2007, 317:807-810.
    • (2007) Science , vol.317 , pp. 807-810
    • Brack, A.S.1    Conboy, M.J.2    Roy, S.3    Lee, M.4    Kuo, C.J.5    Keller, C.6    Rando, T.A.7
  • 68
    • 0142195931 scopus 로고    scopus 로고
    • Hematopoietic senescence is postponed and hematopoietic stem cell function is enhanced by dietary restriction
    • Chen J., Astle C.M., Harrison D.E. Hematopoietic senescence is postponed and hematopoietic stem cell function is enhanced by dietary restriction. Exp Hematol 2003, 31:1097-1103.
    • (2003) Exp Hematol , vol.31 , pp. 1097-1103
    • Chen, J.1    Astle, C.M.2    Harrison, D.E.3
  • 71
    • 0024380947 scopus 로고
    • Numbers and functions of transplantable primitive immunohematopoietic stem cells. Effects of age
    • Harrison D.E., Astle C.M., Stone M. Numbers and functions of transplantable primitive immunohematopoietic stem cells. Effects of age. J Immunol 1989, 142:3833-3840.
    • (1989) J Immunol , vol.142 , pp. 3833-3840
    • Harrison, D.E.1    Astle, C.M.2    Stone, M.3
  • 75
    • 84886924368 scopus 로고    scopus 로고
    • Heterogeneity of young and aged murine hematopoietic stem cells revealed by quantitative clonal analysis using cellular barcoding
    • Verovskaya E., Broekhuis M.J., Zwart E., Ritsema M., van Os R., de Haan G., Bystrykh L.V. Heterogeneity of young and aged murine hematopoietic stem cells revealed by quantitative clonal analysis using cellular barcoding. Blood 2013, 122:523-532.
    • (2013) Blood , vol.122 , pp. 523-532
    • Verovskaya, E.1    Broekhuis, M.J.2    Zwart, E.3    Ritsema, M.4    van Os, R.5    de Haan, G.6    Bystrykh, L.V.7
  • 76
    • 0037326714 scopus 로고    scopus 로고
    • Mobilization of CD34+ cells in elderly patients (>/= 70 years) with multiple myeloma: influence of age, prior therapy, platelet count and mobilization regimen
    • Morris C.L., Siegel E., Barlogie B., Cottler-Fox M., Lin P., Fassas A., Zangari M., Anaissie E., Tricot G. Mobilization of CD34+ cells in elderly patients (>/= 70 years) with multiple myeloma: influence of age, prior therapy, platelet count and mobilization regimen. Br J Haematol 2003, 120:413-423.
    • (2003) Br J Haematol , vol.120 , pp. 413-423
    • Morris, C.L.1    Siegel, E.2    Barlogie, B.3    Cottler-Fox, M.4    Lin, P.5    Fassas, A.6    Zangari, M.7    Anaissie, E.8    Tricot, G.9
  • 77
    • 70449717293 scopus 로고    scopus 로고
    • Safety and efficacy of hematopoietic stem cell collection from mobilized peripheral blood in unrelated volunteers: 12 years of single-center experience in 3928 donors
    • Holig K., Kramer M., Kroschinsky F., Bornhauser M., Mengling T., Schmidt A.H., Rutt C., Ehninger G. Safety and efficacy of hematopoietic stem cell collection from mobilized peripheral blood in unrelated volunteers: 12 years of single-center experience in 3928 donors. Blood 2009, 114:3757-3763.
    • (2009) Blood , vol.114 , pp. 3757-3763
    • Holig, K.1    Kramer, M.2    Kroschinsky, F.3    Bornhauser, M.4    Mengling, T.5    Schmidt, A.H.6    Rutt, C.7    Ehninger, G.8
  • 78
    • 33746513100 scopus 로고    scopus 로고
    • Peripheral blood stem cell yield in 400 normal donors mobilised with granulocyte colony-stimulating factor (G-CSF): impact of age, sex, donor weight and type of G-CSF used
    • Ings S.J., Balsa C., Leverett D., Mackinnon S., Linch D.C., Watts M.J. Peripheral blood stem cell yield in 400 normal donors mobilised with granulocyte colony-stimulating factor (G-CSF): impact of age, sex, donor weight and type of G-CSF used. Br J Haematol 2006, 134:517-525.
    • (2006) Br J Haematol , vol.134 , pp. 517-525
    • Ings, S.J.1    Balsa, C.2    Leverett, D.3    Mackinnon, S.4    Linch, D.C.5    Watts, M.J.6


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