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Volumn 3, Issue 6, 2011, Pages 643-656

Aging-associated changes in hematopoiesis and leukemogenesis: What's the connection?

Author keywords

[No Author keywords available]

Indexed keywords

AGING; ANIMAL; CELL TRANSFORMATION; GENETICS; HEMATOPOIESIS; HUMAN; INNATE IMMUNITY; LEUKEMIA; MOLECULAR EVOLUTION; MUTATION; PATHOPHYSIOLOGY; PHYSIOLOGY; REPRODUCTIVE FITNESS; REVIEW;

EID: 80055110647     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: 10.18632/aging.100351     Document Type: Article
Times cited : (67)

References (113)
  • 1
    • 58149100407 scopus 로고    scopus 로고
    • The ageing immune system: is it ever too old to become young again?
    • Dorshkind K, Montecino-Rodriguez E, Signer RA: The ageing immune system: is it ever too old to become young again? Nat Rev Immunol 2009, 9(1):57-62.
    • (2009) Nat Rev Immunol , vol.9 , Issue.1 , pp. 57-62
    • Dorshkind, K.1    Montecino-Rodriguez, E.2    Signer, R.A.3
  • 2
    • 34147109207 scopus 로고    scopus 로고
    • Hematopoietic stem cell aging: mechanism and consequence
    • Rossi DJ, Bryder D, Weissman IL: Hematopoietic stem cell aging: mechanism and consequence. Exp Gerontol 2007, 42(5):385-390.
    • (2007) Exp Gerontol , vol.42 , Issue.5 , pp. 385-390
    • Rossi, D.J.1    Bryder, D.2    Weissman, I.L.3
  • 3
    • 54549093803 scopus 로고    scopus 로고
    • Ageing, oxidative stress and cancer: paradigms in parallax
    • Benz CC, Yau C: Ageing, oxidative stress and cancer: paradigms in parallax. Nat Rev Cancer 2008, 8(11):875-879.
    • (2008) Nat Rev Cancer , vol.8 , Issue.1 , pp. 875-879
    • Benz, C.C.1    Yau, C.2
  • 5
    • 0034626769 scopus 로고    scopus 로고
    • The age of cancer
    • DePinho RA: The age of cancer. Nature 2000, 408(6809):248-254.
    • (2000) Nature , vol.408 , Issue.680 , pp. 248-254
    • DePinho, R.A.1
  • 6
    • 0037093947 scopus 로고    scopus 로고
    • featuring implications of age and aging on U.S. cancer burden
    • Annual report to the nation on the status of cancer, 1973-1999
    • Edwards BK, Howe HL, Ries LA, Thun MJ, Rosenberg HM, Yancik R, Wingo PA, Jemal A, Feigal EG: Annual report to the nation on the status of cancer, 1973-1999, featuring implications of age and aging on U.S. cancer burden. Cancer 2002, 94(10):2766-2792.
    • (2002) Cancer , vol.94 , Issue.10 , pp. 2766-2792
    • Edwards, B.K.1    Howe, H.L.2    Ries, L.A.3    Thun, M.J.4    Rosenberg, H.M.5    Yancik, R.6    Wingo, P.A.7    Jemal, A.8    Feigal, E.G.9
  • 8
    • 0017167185 scopus 로고
    • The clonal evolution of tumor cell populations
    • Nowell PC: The clonal evolution of tumor cell populations. Science 1976, 194(4260):23-28.
    • (1976) Science , vol.194 , Issue.4260 , pp. 23-28
    • Nowell, P.C.1
  • 9
    • 23144435772 scopus 로고    scopus 로고
    • Tissue, cell and stage specificity of (epi)mutations in cancers
    • Sieber OM, Tomlinson SR, Tomlinson IP: Tissue, cell and stage specificity of (epi)mutations in cancers. Nat Rev Cancer 2005, 5(8):649-655.
    • (2005) Nat Rev Cancer , vol.5 , Issue.8 , pp. 649-655
    • Sieber, O.M.1    Tomlinson, S.R.2    Tomlinson, I.P.3
  • 10
    • 77956858165 scopus 로고    scopus 로고
    • Ionizing radiation and hematopoietic malignancies: altering the adaptive landscape
    • Fleenor CJ, Marusyk A, DeGregori J: Ionizing radiation and hematopoietic malignancies: altering the adaptive landscape. Cell Cycle 2010, 9(15):3005-3011.
    • (2010) Cell Cycle , vol.9 , Issue.15 , pp. 3005-3011
    • Fleenor, C.J.1    Marusyk, A.2    DeGregori, J.3
  • 11
    • 79957895030 scopus 로고    scopus 로고
    • Evolved tumor suppression: why are we so good at not getting cancer?
    • Degregori J: Evolved tumor suppression: why are we so good at not getting cancer? Cancer Res 2011, 71(11):3739-3744.
    • (2011) Cancer Res , vol.71 , Issue.11 , pp. 3739-3744
    • Degregori, J.1
  • 12
    • 77953811725 scopus 로고    scopus 로고
    • Cancer stem cells: back to Darwin?
    • Greaves M: Cancer stem cells: back to Darwin? Semin Cancer Biol 2010, 20(2):65-70.
    • (2010) Semin Cancer Biol , vol.20 , Issue.2 , pp. 65-70
    • Greaves, M.1
  • 14
    • 34548179310 scopus 로고    scopus 로고
    • Cancer and ageing: convergent and divergent mechanisms
    • Serrano M, Blasco MA: Cancer and ageing: convergent and divergent mechanisms. Nat Rev Mol Cell Biol 2007, 8(9):715-722.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , Issue.9 , pp. 715-722
    • Serrano, M.1    Blasco, M.A.2
  • 15
    • 0036513029 scopus 로고    scopus 로고
    • Oncogenic resistance to growth-limiting conditions
    • Blagosklonny MV: Oncogenic resistance to growth-limiting conditions. Nat Rev Cancer 2002, 2(3):221-225.
    • (2002) Nat Rev Cancer , vol.2 , Issue.3 , pp. 221-225
    • Bagosklonny, M.V.1
  • 16
    • 36549083391 scopus 로고    scopus 로고
    • Declining cellular fitness with age promotes cancer initiation by selecting for adaptive oncogenic mutations
    • Marusyk A, DeGregori J: Declining cellular fitness with age promotes cancer initiation by selecting for adaptive oncogenic mutations. Biochim Biophys Acta 2008, 1785(1):1-11.
    • (2008) Biochim Biophys Acta , vol.1785 , Issue.1 , pp. 1-11
    • Marusyk, A.1    DeGregori, J.2
  • 17
    • 58149355479 scopus 로고    scopus 로고
    • Carcinogenesis and aging 20 years after: escaping horizon
    • Anisimov VN: Carcinogenesis and aging 20 years after: escaping horizon. Mech Ageing Dev 2009, 130(1-2):105-121.
    • (2009) Mech Ageing Dev , vol.130 , Issue.1-2 , pp. 105-121
    • Anisimov, V.N.1
  • 18
    • 36249018885 scopus 로고    scopus 로고
    • Hematopoietic stem cell aging: wrinkles in stem cell potential
    • Chambers SM, Goodell MA: Hematopoietic stem cell aging: wrinkles in stem cell potential. Stem Cell Rev 2007, 3(3):201-211.
    • (2007) Stem Cell Rev , vol.3 , Issue.3 , pp. 201-211
    • Chambers, S.M.1    Goodell, M.A.2
  • 19
    • 0035902067 scopus 로고    scopus 로고
    • Cancer epidemiology in the last century and the next decade
    • Peto J: Cancer epidemiology in the last century and the next decade. Nature 2001, 411(6835):390-395.
    • (2001) Nature , vol.411 , Issue.6835 , pp. 390-395
    • Peto, J.1
  • 20
    • 13944262937 scopus 로고    scopus 로고
    • Understanding the odd science of aging
    • Kirkwood TB: Understanding the odd science of aging. Cell 2005, 120(4):437-447.
    • (2005) Cell , vol.120 , Issue.4 , pp. 437-447
    • Kirkwood, T.B.1
  • 21
    • 36549062401 scopus 로고    scopus 로고
    • Impact of niche aging on thymic regeneration and immune reconstitution
    • Chidgey A, Dudakov J, Seach N, Boyd R: Impact of niche aging on thymic regeneration and immune reconstitution. Semin Immunol 2007, 19(5):331-340.
    • (2007) Semin Immunol , vol.19 , Issue.5 , pp. 331-340
    • Chidgey, A.1    Dudakov, J.2    Seach, N.3    Boyd, R.4
  • 22
    • 68149148866 scopus 로고    scopus 로고
    • Age-associated declines in immune system development and function: causes, consequences, and reversal
    • Dorshkind K, Swain S: Age-associated declines in immune system development and function: causes, consequences, and reversal. Curr Opin Immunol 2009, 21(4):404-407.
    • (2009) Curr Opin Immunol , vol.21 , Issue.4 , pp. 404-407
    • Dorshkind, K.1    Swain, S.2
  • 25
    • 1142275269 scopus 로고    scopus 로고
    • Age-related changes in lymphocyte development and function
    • Linton PJ, Dorshkind K: Age-related changes in lymphocyte development and function. Nat Immunol 2004, 5(2):133-139.
    • (2004) Nat Immunol , vol.5 , Issue.2 , pp. 133-139
    • Linton, P.J.1    Dorshkind, K.2
  • 26
    • 34548153747 scopus 로고    scopus 로고
    • How stem cells age and why this makes us grow old
    • Sharpless NE, DePinho RA: How stem cells age and why this makes us grow old. Nat Rev Mol Cell Biol 2007, 8(9):703-713.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , Issue.9 , pp. 703-713
    • Sharpless, N.E.1    DePinho, R.A.2
  • 27
    • 23044484028 scopus 로고    scopus 로고
    • Linking age-related defects in B lymphopoiesis to the aging of hematopoietic stem cells
    • Miller JP, Allman D: Linking age-related defects in B lymphopoiesis to the aging of hematopoietic stem cells. Semin Immunol 2005, 17(5):321-329.
    • (2005) Semin Immunol , vol.17 , Issue.5 , pp. 321-329
    • Miller, J.P.1    Allman, D.2
  • 28
    • 58149496504 scopus 로고    scopus 로고
    • Stem cells and aging in the hematopoietic system
    • Warren LA, Rossi DJ: Stem cells and aging in the hematopoietic system. Mech Ageing Dev 2009, 130(1-2):46-53.
    • (2009) Mech Ageing Dev , vol.130 , Issue.1-2 , pp. 46-53
    • Warren, L.A.1    Rossi, D.J.2
  • 29
    • 77952075843 scopus 로고    scopus 로고
    • Fountain of Youth: aged blood-forming stem cells could be rejuvenated by young microenvironment
    • Yin T, Li L: Fountain of Youth: aged blood-forming stem cells could be rejuvenated by young microenvironment. Cell Res 2010, 20(5):504-505.
    • (2010) Cell Res , vol.20 , Issue.5 , pp. 504-505
    • Yin, T.1    Li, L.2
  • 30
    • 67651098996 scopus 로고    scopus 로고
    • Altered cellular dynamics and endosteal location of aged early hematopoietic progenitor cells revealed by time-lapse intravital imaging in long bones
    • Kohler A, Schmithorst V, Filippi MD, Ryan MA, Daria D, Gunzer M, Geiger H: Altered cellular dynamics and endosteal location of aged early hematopoietic progenitor cells revealed by time-lapse intravital imaging in long bones. Blood 2009, 114(2):290-298.
    • (2009) Blood , vol.114 , Issue.2 , pp. 290-298
    • Kohler, A.1    Schmithorst, V.2    Filippi, M.D.3    Ryan, M.A.4    Daria, D.5    Gunzer, M.6    Geiger, H.7
  • 33
    • 77950860807 scopus 로고    scopus 로고
    • Hypoxia mediates low cell-cycle activity and increases the proportion of long-term-reconstituting hematopoietic stem cells during in vitro culture
    • Eliasson P, Rehn M, Hammar P, Larsson P, Sirenko O, Flippin LA, Cammenga J, Jonsson JI: Hypoxia mediates low cell-cycle activity and increases the proportion of long-term-reconstituting hematopoietic stem cells during in vitro culture. Exp Hematol 2010, 38(4):301-310 e302.
    • (2010) Exp Hematol , vol.38 , Issue.4
    • Eliasson, P.1    Rehn, M.2    Hammar, P.3    Larsson, P.4    Sirenko, O.5    Flippin, L.A.6    Cammenga, J.7    Jonsson, J.I.8
  • 34
    • 32944474237 scopus 로고    scopus 로고
    • Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer
    • Karin M, Lawrence T, Nizet V: Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer. Cell 2006, 124(4):823-835.
    • (2006) Cell , vol.124 , Issue.4 , pp. 823-835
    • Karin, M.1    Lawrence, T.2    Nizet, V.3
  • 35
    • 34250007142 scopus 로고    scopus 로고
    • Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age
    • Rossi DJ, Bryder D, Seita J, Nussenzweig A, Hoeijmakers J, Weissman IL: Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. Nature 2007, 447(7145):725-729.
    • (2007) Nature , vol.447 , Issue.7145 , pp. 725-729
    • Rossi, D.J.1    Bryder, D.2    Seita, J.3    Nussenzweig, A.4    Hoeijmakers, J.5    Weissman, I.L.6
  • 37
    • 77950418688 scopus 로고    scopus 로고
    • Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion
    • Beerman I, Bhattacharya D, Zandi S, Sigvardsson M, Weissman IL, Bryder D, Rossi DJ: Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion. Proc Natl Acad Sci U S A 2010, 107(12):5465-5470.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , Issue.12 , pp. 5465-5470
    • Beerman, I.1    Bhattacharya, D.2    Zandi, S.3    Sigvardsson, M.4    Weissman, I.L.5    Bryder, D.6    Rossi, D.J.7
  • 40
  • 41
    • 23744439044 scopus 로고    scopus 로고
    • Effects of aging on the homing and engraftment of murine hematopoietic stem and progenitor cells
    • Liang Y, Van Zant G, Szilvassy SJ: Effects of aging on the homing and engraftment of murine hematopoietic stem and progenitor cells. Blood 2005, 106(4):1479-1487.
    • (2005) Blood , vol.106 , Issue.4 , pp. 1479-1487
    • Liang, Y.1    Van Zant, G.2    Szilvassy, S.J.3
  • 42
    • 0034613690 scopus 로고    scopus 로고
    • Age-associated characteristics of murine hematopoietic stem cells
    • Sudo K, Ema H, Morita Y, Nakauchi H: Age-associated characteristics of murine hematopoietic stem cells. J Exp Med 2000, 192(9):1273-1280.
    • (2000) J Exp Med , vol.192 , Issue.9 , pp. 1273-1280
    • Sudo, K.1    Ema, H.2    Morita, Y.3    Nakauchi, H.4
  • 43
    • 0033562357 scopus 로고    scopus 로고
    • Dynamic changes in mouse hematopoietic stem cell numbers during aging
    • de Haan G, Van Zant G: Dynamic changes in mouse hematopoietic stem cell numbers during aging. Blood 1999, 93(10):3294-3301.
    • (1999) Blood , vol.93 , Issue.10 , pp. 3294-3301
    • de Haan, G.1    Van Zant, G.2
  • 44
    • 65049086788 scopus 로고    scopus 로고
    • Hematopoietic stem cell aging is associated with functional decline and delayed cell cycle progression
    • Noda S, Ichikawa H, Miyoshi H: Hematopoietic stem cell aging is associated with functional decline and delayed cell cycle progression. Biochem Biophys Res Commun 2009, 383(2):210-215.
    • (2009) Biochem Biophys Res Commun , vol.383 , Issue.2 , pp. 210-215
    • Noda, S.1    Ichikawa, H.2    Miyoshi, H.3
  • 45
    • 0025281056 scopus 로고    scopus 로고
    • Genotype-restricted growth and aging patterns in hematopoietic stem cell populations of allophenic mice
    • Van Zant G, Holland BP, Eldridge PW, Chen JJ: Genotype-restricted growth and aging patterns in hematopoietic stem cell populations of allophenic mice. J Exp Med 1990, 171(5):1547-1565.
    • J Exp Med 1990 , vol.171 , Issue.5 , pp. 1547-1565
    • Van Zant, G.1    Holland, B.P.2    Eldridge, P.W.3    Chen, J.J.4
  • 46
    • 0032920969 scopus 로고    scopus 로고
    • Development and aging of primitive hematopoietic stem cells in BALB/cBy mice
    • Chen J, Astle CM, Harrison DE: Development and aging of primitive hematopoietic stem cells in BALB/cBy mice. Exp Hematol 1999, 27(5):928-935.
    • (1999) Exp Hematol , vol.27 , Issue.5 , pp. 928-935
    • Chen, J.1    Astle, C.M.2    Harrison, D.E.3
  • 47
    • 0034008968 scopus 로고    scopus 로고
    • Genetic regulation of primitive hematopoietic stem cell senescence
    • Chen J, Astle CM, Harrison DE: Genetic regulation of primitive hematopoietic stem cell senescence. Exp Hematol 2000, 28(4):442-450.
    • (2000) Exp Hematol , vol.28 , Issue.4 , pp. 442-450
    • Chen, J.1    Astle, C.M.2    Harrison, D.E.3
  • 49
    • 0035496909 scopus 로고    scopus 로고
    • Donor characteristics as risk factors in recipients after transplantation of bone marrow from unrelated donors: the effect of donor age
    • Kollman C, Howe CW, Anasetti C, Antin JH, Davies SM, Filipovich AH, Hegland J, Kamani N, Kernan NA, King R et al: Donor characteristics as risk factors in recipients after transplantation of bone marrow from unrelated donors: the effect of donor age. Blood 2001, 98(7):2043-2051.
    • (2001) Blood , vol.98 , Issue.7 , pp. 2043-2051
    • Kollman, C.1    Howe, C.W.2    Anasetti, C.3    Antin, J.H.4    Davies, S.M.5    Filipovich, A.H.6    Hegland, J.7    Kamani, N.8    Kernan, N.A.9    King, R.10
  • 50
    • 50149099346 scopus 로고    scopus 로고
    • Acquired hematopoietic stem cell defects determine B-cell repertoire changes associated with aging
    • Guerrettaz LM, Johnson SA, Cambier JC: Acquired hematopoietic stem cell defects determine B-cell repertoire changes associated with aging. Proc Natl Acad Sci U S A 2008, 105(33):11898-11902.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.33 , pp. 11898-11902
    • Guerrettaz, L.M.1    Johnson, S.A.2    Cambier, J.C.3
  • 51
    • 2542473275 scopus 로고    scopus 로고
    • Myeloid-biased hematopoietic stem cells have extensive self-renewal capacity but generate diminished lymphoid progeny with impaired IL-7 responsiveness
    • Muller-Sieburg CE, Cho RH, Karlsson L, Huang JF, Sieburg HB: Myeloid-biased hematopoietic stem cells have extensive self-renewal capacity but generate diminished lymphoid progeny with impaired IL-7 responsiveness. Blood 2004, 103(11):4111-4118.
    • (2004) Blood , vol.103 , Issue.11 , pp. 4111-4118
    • Muller-Sieburg, C.E.1    Cho, R.H.2    Karlsson, L.3    Huang, J.F.4    Sieburg, H.B.5
  • 52
    • 47049099198 scopus 로고    scopus 로고
    • A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cells
    • Cho RH, Sieburg HB, Muller-Sieburg CE: A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cells. Blood 2008, 111(12):5553-5561.
    • (2008) Blood , vol.111 , Issue.12 , pp. 5553-5561
    • Cho, R.H.1    Sieburg, H.B.2    Muller-Sieburg, C.E.3
  • 53
    • 77449145533 scopus 로고    scopus 로고
    • Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1
    • Challen GA, Boles NC, Chambers SM, Goodell MA: Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1. Cell Stem Cell 2010, 6(3):265-278.
    • (2010) Cell Stem Cell , vol.6 , Issue.3 , pp. 265-278
    • Challen, G.A.1    Boles, N.C.2    Chambers, S.M.3    Goodell, M.A.4
  • 54
    • 67650587142 scopus 로고    scopus 로고
    • Prospective isolation and molecular characterization of hematopoietic stem cells with durable self-renewal potential
    • Kent DG, Copley MR, Benz C, Wohrer S, Dykstra BJ, Ma E, Cheyne J, Zhao Y, Bowie MB, Gasparetto M et al: Prospective isolation and molecular characterization of hematopoietic stem cells with durable self-renewal potential. Blood 2009, 113(25):6342-6350.
    • (2009) Blood , vol.113 , Issue.25 , pp. 6342-6350
    • Kent, D.G.1    Copley, M.R.2    Benz, C.3    Wohrer, S.4    Dykstra, B.J.5    Ma, E.6    Cheyne, J.7    Zhao, Y.8    Bowie, M.B.9    Gasparetto, M.10
  • 55
    • 22344437262 scopus 로고    scopus 로고
    • Inflammation and the reciprocal production of granulocytes and lymphocytes in bone marrow
    • Ueda Y, Kondo M, Kelsoe G: Inflammation and the reciprocal production of granulocytes and lymphocytes in bone marrow. J Exp Med 2005, 201(11):1771-1780.
    • (2005) J Exp Med , vol.201 , Issue.11 , pp. 1771-1780
    • Ueda, Y.1    Kondo, M.2    Kelsoe, G.3
  • 56
    • 34548852838 scopus 로고    scopus 로고
    • Age-related defects in B lymphopoiesis underlie the myeloid dominance of adult leukemia
    • Signer RA, Montecino-Rodriguez E, Witte ON, McLaughlin J, Dorshkind K: Age-related defects in B lymphopoiesis underlie the myeloid dominance of adult leukemia. Blood 2007, 110(6):1831-1839.
    • (2007) Blood , vol.110 , Issue.6 , pp. 1831-1839
    • Signer, R.A.1    Montecino-Rodriguez, E.2    Witte, O.N.3    McLaughlin, J.4    Dorshkind, K.5
  • 60
    • 25844459154 scopus 로고    scopus 로고
    • NF-kappaB linking inflammation and immunity to cancer development and progression
    • Karin M, Greten FR: NF-kappaB: linking inflammation and immunity to cancer development and progression. Nat Rev Immunol 2005, 5(10):749-759.
    • (2005) Nat Rev Immunol , vol.5 , Issue.10 , pp. 749-759
    • Karin, M.1    Greten, F.R.2
  • 61
    • 0033862739 scopus 로고    scopus 로고
    • Thymic involution in aging
    • Aspinall R, Andrew D: Thymic involution in aging. J Clin Immunol 2000, 20(4):250-256.
    • (2000) J Clin Immunol , vol.20 , Issue.4 , pp. 250-256
    • Aspinall, R.1    Andrew, D.2
  • 62
    • 34548030239 scopus 로고    scopus 로고
    • Multiple prethymic defects underlie age-related loss of T progenitor competence
    • Zediak VP, Maillard I, Bhandoola A: Multiple prethymic defects underlie age-related loss of T progenitor competence. Blood 2007.
    • (2007) Blood
    • Zediak, V.P.1    Maillard, I.2    Bhandoola, A.3
  • 64
    • 78650434560 scopus 로고    scopus 로고
    • Review of human immunodeficiency virus (HIV) and squamous lesions of the uterine cervix
    • Pantanowitz L, Michelow P: Review of human immunodeficiency virus (HIV) and squamous lesions of the uterine cervix. Diagn Cytopathol, 39(1):65-72.
    • Diagn Cytopathol , vol.39 , Issue.1 , pp. 65-72
    • Pantanowitz, L.1    Michelow, P.2
  • 65
    • 56149122292 scopus 로고    scopus 로고
    • HIV, human papillomavirus, and cervical neoplasia and cancer in the era of highly active antiretroviral therapy
    • De Vuyst H, Lillo F, Broutet N, Smith JS: HIV, human papillomavirus, and cervical neoplasia and cancer in the era of highly active antiretroviral therapy. Eur J Cancer Prev 2008, 17(6):545-554.
    • (2008) Eur J Cancer Prev , vol.17 , Issue.6 , pp. 545-554
    • De Vuyst, H.1    Lillo, F.2    Broutet, N.3    Smith, J.S.4
  • 66
    • 1542378882 scopus 로고    scopus 로고
    • The impact of HIV antiviral therapy on human papillomavirus (HPV) infections and HPV-related diseases
    • Heard I, Palefsky JM, Kazatchkine MD: The impact of HIV antiviral therapy on human papillomavirus (HPV) infections and HPV-related diseases. Antivir Ther 2004, 9(1):13-22.
    • (2004) Antivir Ther , vol.9 , Issue.1 , pp. 13-22
    • Heard, I.1    Palefsky, J.M.2    Kazatchkine, M.D.3
  • 68
    • 4143141823 scopus 로고    scopus 로고
    • The immunobiology of cancer immunosurveillance and immunoediting
    • Dunn GP, Old LJ, Schreiber RD: The immunobiology of cancer immunosurveillance and immunoediting. Immunity 2004, 21(2):137-148.
    • (2004) Immunity , vol.21 , Issue.2 , pp. 137-148
    • Dunn, G.P.1    Old, L.J.2    Schreiber, R.D.3
  • 69
    • 77954563614 scopus 로고    scopus 로고
    • Interactions between lymphocytes and myeloid cells regulate pro- versus anti-tumor immunity
    • DeNardo DG, Andreu P, Coussens LM: Interactions between lymphocytes and myeloid cells regulate pro- versus anti-tumor immunity. Cancer Metastasis Rev 2010, 29(2):309-316.
    • (2010) Cancer Metastasis Rev , vol.29 , Issue.2 , pp. 309-316
    • DeNardo, D.G.1    Andreu, P.2    Coussens, L.M.3
  • 71
    • 34147194404 scopus 로고    scopus 로고
    • Aging, B lymphopoiesis, and patterns of leukemogenesis
    • Signer RA, Montecino-Rodriguez E, Dorshkind K: Aging, B lymphopoiesis, and patterns of leukemogenesis. Exp Gerontol 2007, 42(5):391-395.
    • (2007) Exp Gerontol , vol.42 , Issue.5 , pp. 391-395
    • Signer, R.A.1    Montecino-Rodriguez, E.2    Dorshkind, K.3
  • 72
  • 73
    • 0142217362 scopus 로고    scopus 로고
    • Aged mice exhibit distinct B cell precursor phenotypes differing in activation, proliferation and apoptosis
    • Van der Put E, Sherwood EM, Blomberg BB, Riley RL: Aged mice exhibit distinct B cell precursor phenotypes differing in activation, proliferation and apoptosis. Exp Gerontol 2003, 38(10):1137-1147.
    • (2003) Exp Gerontol , vol.38 , Issue.10 , pp. 1137-1147
    • Van der Put, E.1    Sherwood, E.M.2    Blomberg, B.B.3    Riley, R.L.4
  • 74
    • 20344405958 scopus 로고    scopus 로고
    • The aging of early B-cell precursors
    • Allman D, Miller JP: The aging of early B-cell precursors. Immunol Rev 2005, 205:18-29.
    • (2005) Immunol Rev , vol.205 , pp. 18-29
    • Allman, D.1    Miller, J.P.2
  • 75
    • 30744451406 scopus 로고    scopus 로고
    • Effects of aging on the common lymphoid progenitor to pro-B cell transition
    • Min H, Montecino-Rodriguez E, Dorshkind K: Effects of aging on the common lymphoid progenitor to pro-B cell transition. J Immunol 2006, 176(2):1007-1012.
    • (2006) J Immunol , vol.176 , Issue.2 , pp. 1007-1012
    • Min, H.1    Montecino-Rodriguez, E.2    Dorshkind, K.3
  • 76
    • 0031568406 scopus 로고    scopus 로고
    • Development of B cells in aged mice: decline in the ability of pro-B cells to respond to IL-7 but not to other growth factors
    • Stephan RP, Lill-Elghanian DA, Witte PL: Development of B cells in aged mice: decline in the ability of pro-B cells to respond to IL-7 but not to other growth factors. J Immunol 1997, 158(4):1598-1609.
    • (1997) J Immunol , vol.158 , Issue.4 , pp. 1598-1609
    • Stephan, R.P.1    Lill-Elghanian, D.A.2    Witte, P.L.3
  • 78
    • 0037094083 scopus 로고    scopus 로고
    • Aging-dependent exclusion of antigen-inexperienced cells from the peripheral B cell repertoire
    • Johnson SA, Rozzo SJ, Cambier JC: Aging-dependent exclusion of antigen-inexperienced cells from the peripheral B cell repertoire. J Immunol 2002, 168(10):5014-5023.
    • (2002) J Immunol , vol.168 , Issue.10 , pp. 5014-5023
    • Johnson, S.A.1    Rozzo, S.J.2    Cambier, J.C.3
  • 79
    • 0028968187 scopus 로고
    • Long-term culture system for selective growth of human B-cell progenitors
    • Rawlings DJ, Quan SG, Kato RM, Witte ON: Long-term culture system for selective growth of human B-cell progenitors. Proc Natl Acad Sci U S A 1995, 92(5):1570-1574.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , Issue.5 , pp. 1570-1574
    • Rawlings, D.J.1    Quan, S.G.2    Kato, R.M.3    Witte, O.N.4
  • 80
    • 0029812552 scopus 로고    scopus 로고
    • Interleukin 7 independent development of human B cells
    • Prieyl JA, LeBien TW: Interleukin 7 independent development of human B cells. Proc Natl Acad Sci U S A 1996, 93(19):10348-10353.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , Issue.19 , pp. 10348-10353
    • Prieyl, J.A.1    LeBien, T.W.2
  • 81
    • 0036197729 scopus 로고    scopus 로고
    • The effect of age on B cell development and humoral immunity
    • Weksler ME, Goodhardt M, Szabo P: The effect of age on B cell development and humoral immunity. Springer Semin Immunopathol 2002, 24(1):35-52.
    • (2002) Springer Semin Immunopathol , vol.24 , Issue.1 , pp. 35-52
    • Weksler, M.E.1    Goodhardt, M.2    Szabo, P.3
  • 82
    • 0033854211 scopus 로고    scopus 로고
    • The effect of age on the B-cell repertoire
    • Weksler ME, Szabo P: The effect of age on the B-cell repertoire. J Clin Immunol 2000, 20(4):240-249.
    • (2000) J Clin Immunol , vol.20 , Issue.4 , pp. 240-249
    • Weksler, M.E.1    Szabo, P.2
  • 83
    • 45949103917 scopus 로고    scopus 로고
    • Aging down-regulates the transcription factor E2A, activation-induced cytidine deaminase, and Ig class switch in human B cells
    • Frasca D, Landin AM, Lechner SC, Ryan JG, Schwartz R, Riley RL, Blomberg BB: Aging down-regulates the transcription factor E2A, activation-induced cytidine deaminase, and Ig class switch in human B cells. J Immunol 2008, 180(8):5283-5290.
    • (2008) J Immunol , vol.180 , Issue.8 , pp. 5283-5290
    • Frasca, D.1    Landin, A.M.2    Lechner, S.C.3    Ryan, J.G.4    Schwartz, R.5    Riley, R.L.6    Blomberg, B.B.7
  • 84
    • 4444320808 scopus 로고    scopus 로고
    • Ageing, autoimmunity and arthritis: senescence of the B cell compartment - implications for humoral immunity
    • Johnson SA, Cambier JC: Ageing, autoimmunity and arthritis: senescence of the B cell compartment - implications for humoral immunity. Arthritis Res Ther 2004, 6(4):131-139.
    • (2004) Arthritis Res Ther , vol.6 , Issue.4 , pp. 131-139
    • Johnson, S.A.1    Cambier, J.C.2
  • 85
    • 70349859881 scopus 로고    scopus 로고
    • DNA damage, aging, and cancer
    • Hoeijmakers JH: DNA damage, aging, and cancer. N Engl J Med 2009, 361(15):1475-1485.
    • (2009) N Engl J Med , vol.361 , Issue.15 , pp. 1475-1485
    • Hoeijmakers, J.H.1
  • 86
    • 13944270339 scopus 로고    scopus 로고
    • Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors
    • Campisi J: Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell 2005, 120(4):513-522.
    • (2005) Cell , vol.120 , Issue.4 , pp. 513-522
    • Campisi, J.1
  • 87
    • 77950265945 scopus 로고    scopus 로고
    • Linking functional decline of telomeres, mitochondria and stem cells during ageing
    • Sahin E, Depinho RA: Linking functional decline of telomeres, mitochondria and stem cells during ageing. Nature, 464(7288):520-528.
    • Nature , vol.464 , Issue.7288 , pp. 520-528
    • Sahin, E.1    Depinho, R.A.2
  • 88
    • 85047689866 scopus 로고    scopus 로고
    • Telomeres, stem cells, senescence, and cancer
    • Sharpless NE, DePinho RA: Telomeres, stem cells, senescence, and cancer. J Clin Invest 2004, 113(2):160-168.
    • (2004) J Clin Invest , vol.113 , Issue.2 , pp. 160-168
    • Sharpless, N.E.1    DePinho, R.A.2
  • 89
    • 0037067656 scopus 로고    scopus 로고
    • p53: good cop/bad cop
    • Sharpless NE, DePinho RA: p53: good cop/bad cop. Cell 2002, 110(1):9-12.
    • (2002) Cell , vol.110 , Issue.1 , pp. 9-12
    • Sharpless, N.E.1    DePinho, R.A.2
  • 90
    • 69949168092 scopus 로고    scopus 로고
    • Timed somatic deletion of p53 in mice reveals age-associated differences in tumor progression
    • Hinkal G, Parikh N, Donehower LA: Timed somatic deletion of p53 in mice reveals age-associated differences in tumor progression. PLoS One 2009, 4(8):e6654.
    • (2009) PLoS One , vol.4 , Issue.8
    • Hinkal, G.1    Parikh, N.2    Donehower, L.A.3
  • 91
    • 34547941973 scopus 로고    scopus 로고
    • The common biology of cancer and ageing
    • Finkel T, Serrano M, Blasco MA: The common biology of cancer and ageing. Nature 2007, 448(7155):767-774.
    • (2007) Nature , vol.448 , Issue.7155 , pp. 767-774
    • Finkel, T.1    Serrano, M.2    Blasco, M.A.3
  • 93
    • 0028910530 scopus 로고
    • Does telomere shortening drive selection for p53 mutation in human cancer?
    • Wynford-Thomas D, Bond JA, Wyllie FS, Jones CJ: Does telomere shortening drive selection for p53 mutation in human cancer? Mol Carcinog 1995, 12(3):119-123.
    • (1995) Mol Carcinog , vol.12 , Issue.3 , pp. 119-123
    • Wynford-Thomas, D.1    Bond, J.A.2    Wyllie, F.S.3    Jones, C.J.4
  • 94
    • 34547159757 scopus 로고    scopus 로고
    • p53 mediates senescence-like arrest induced by chronic replicational stress
    • Marusyk A, Wheeler LJ, Mathews CK, DeGregori J: p53 mediates senescence-like arrest induced by chronic replicational stress. Mol Cell Biol 2007, 27(15):5336-5351.
    • (2007) Mol Cell Biol , vol.27 , Issue.15 , pp. 5336-5351
    • Marusyk, A.1    Wheeler, L.J.2    Mathews, C.K.3    DeGregori, J.4
  • 98
    • 56549120340 scopus 로고    scopus 로고
    • Aging and cancer resistance in lymphoid progenitors are linked processes conferred by p16Ink4a and Arf
    • Signer RA, Montecino-Rodriguez E, Witte ON, Dorshkind K: Aging and cancer resistance in lymphoid progenitors are linked processes conferred by p16Ink4a and Arf. Genes Dev 2008, 22(22):3115-3120.
    • (2008) Genes Dev , vol.22 , Issue.22 , pp. 3115-3120
    • Signer, R.A.1    Montecino-Rodriguez, E.2    Witte, O.N.3    Dorshkind, K.4
  • 99
    • 50849110457 scopus 로고    scopus 로고
    • Prevention of cancer by inhibiting aging
    • Blagosklonny MV: Prevention of cancer by inhibiting aging. Cancer Biol Ther 2008, 7(10):1520-1524.
    • (2008) Cancer Biol Ther , vol.7 , Issue.10 , pp. 1520-1524
    • Blagosklonny, M.V.1
  • 100
    • 33745481332 scopus 로고    scopus 로고
    • B-cell chronic lymphocytic leukemia, a clonal disease of B lymphocytes with receptors that vary in specificity for (auto)antigens
    • Chiorazzi N, Hatzi K, Albesiano E: B-cell chronic lymphocytic leukemia, a clonal disease of B lymphocytes with receptors that vary in specificity for (auto)antigens. Ann N Y Acad Sci 2005, 1062:1-12.
    • (2005) Ann N Y Acad Sci , vol.1062 , pp. 1-12
    • Chiorazzi, N.1    Hatzi, K.2    Albesiano, E.3
  • 101
    • 79951535539 scopus 로고    scopus 로고
    • Acute myeloid leukaemia in the elderly: a review
    • Pollyea DA, Kohrt HE, Medeiros BC: Acute myeloid leukaemia in the elderly: a review. Br J Haematol, 152(5):524-542.
    • Br J Haematol , vol.152 , Issue.5 , pp. 524-542
    • Pollyea, D.A.1    Kohrt, H.E.2    Medeiros, B.C.3
  • 102
    • 14644425319 scopus 로고    scopus 로고
    • Mechanisms of BCR-ABL in the pathogenesis of chronic myelogenous leukaemia
    • Ren R: Mechanisms of BCR-ABL in the pathogenesis of chronic myelogenous leukaemia. Nat Rev Cancer 2005, 5(3):172-183.
    • (2005) Nat Rev Cancer , vol.5 , Issue.3 , pp. 172-183
    • Ren, R.1
  • 103
    • 0030015814 scopus 로고    scopus 로고
    • Estimation of the number of mutations necessary to cause chronic myeloid leukaemia from epidemiological data
    • Vickers M: Estimation of the number of mutations necessary to cause chronic myeloid leukaemia from epidemiological data. Br J Haematol 1996, 94(1):1-4.
    • (1996) Br J Haematol , vol.94 , Issue.1 , pp. 1-4
    • Vickers, M.1
  • 106
    • 58049202768 scopus 로고    scopus 로고
    • Stem cell aging: survival of the laziest?
    • Muller-Sieburg C, Sieburg HB: Stem cell aging: survival of the laziest? Cell Cycle 2008, 7(24):3798-3804.
    • (2008) Cell Cycle , vol.7 , Issue.24 , pp. 3798-3804
    • Muller-Sieburg, C.1    Sieburg, H.B.2
  • 107
    • 0038806560 scopus 로고    scopus 로고
    • Major age-related changes of mouse hematopoietic stem/progenitor cells
    • Kim M, Moon HB, Spangrude GJ: Major age-related changes of mouse hematopoietic stem/progenitor cells. Ann N Y Acad Sci 2003, 996:195-208.
    • (2003) Ann N Y Acad Sci , vol.996 , pp. 195-208
    • Kim, M.1    Moon, H.B.2    Spangrude, G.J.3
  • 108
    • 0020650035 scopus 로고
    • Background data and variations in tumor rates of control rats and mice
    • Ward JM: Background data and variations in tumor rates of control rats and mice. Prog Exp Tumor Res 1983, 26:241-258.
    • (1983) Prog Exp Tumor Res , vol.26 , pp. 241-258
    • Ward, J.M.1
  • 109
    • 0027185780 scopus 로고
    • The morphology, immunohistochemistry, and incidence of hematopoietic neoplasms in mice and rats
    • Frith CH, Ward JM, Chandra M: The morphology, immunohistochemistry, and incidence of hematopoietic neoplasms in mice and rats. Toxicol Pathol 1993, 21(2):206-218.
    • (1993) Toxicol Pathol , vol.21 , Issue.2 , pp. 206-218
    • Frith, C.H.1    Ward, J.M.2    Chandra, M.3
  • 110
    • 79956033992 scopus 로고    scopus 로고
    • The stem cell fitness landscape and pathways of molecular leukemogenesis
    • Bagby GC, Fleischman AG: The stem cell fitness landscape and pathways of molecular leukemogenesis. Front Biosci (Schol Ed) 2011, 3:487-500.
    • (2011) Front Biosci (Schol Ed) , vol.3 , pp. 487-500
    • Bagby, G.C.1    Fleischman, A.G.2
  • 112
    • 79959565462 scopus 로고    scopus 로고
    • Leukemogenesis and ageing: 'fit for transformation'?
    • Greaves M: Leukemogenesis and ageing: 'fit for transformation'? Aging (Albany NY), 3(2):79-80.
    • Aging (Albany NY) , vol.3 , Issue.2 , pp. 79-80
    • Greaves, M.1
  • 113
    • 13944261231 scopus 로고    scopus 로고
    • Rejuvenation of aged progenitor cells by exposure to a young systemic environment
    • Conboy IM, Conboy MJ, Wagers AJ, Girma ER, Weissman IL, Rando TA: Rejuvenation of aged progenitor cells by exposure to a young systemic environment. Nature 2005, 433(7027):760-764.
    • (2005) Nature , vol.433 , Issue.7027 , pp. 760-764
    • Conboy, I.M.1    Conboy, M.J.2    Wagers, A.J.3    Girma, E.R.4    Weissman, I.L.5    Rando, T.A.6


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