Declining lymphoid progenitor fitness promotes aging-associated leukemogenesis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 50, 2010, Pages 21713-21718

  Henry, Curtis J ^a   Marusyk, Andriy ^a,c   Zaberezhnyy, Vadym ^a   Adane, Biniam ^a   DeGregori, James ^a,b  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b Children's Hospital Colorado   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

AKT; Chronic myelogenous; Evolution; Immunosenescence; Leukemia; STAT5

Indexed keywords

BCR ABL PROTEIN; INTERLEUKIN 7;

AGING; ANIMAL CELL; ARTICLE; CELL SELECTION; CONTROLLED STUDY; FEMALE; LEUKEMIA; LEUKEMOGENESIS; LYMPHOID PROGENITOR CELL; LYMPHOPOIESIS; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

AGING; ANIMALS; BONE MARROW TRANSPLANTATION; FEMALE; FUSION PROTEINS, BCR-ABL; GENETIC FITNESS; HEMATOPOIETIC STEM CELLS; HUMANS; INTERLEUKIN-7; LEUKEMIA; LYMPHOPOIESIS; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; SIGNAL TRANSDUCTION; STEM CELLS;

EID: 78650744017     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1005486107     Document Type: Article

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