Genetic regulation of primitive hematopoietic stem cell senescence

Experimental Hematology

Volumn 28, Issue 4, 2000, Pages 442-450

  Chen, Jichun ^a   Astle, Clinton M ^a   Harrison, David E ^a  

^a JACKSON LABORATORY   (United States)

Author keywords

Genetic regulation; Mouse; Primitive hematopoietic stem cell; Self renewal; Senescence

Indexed keywords

ANIMAL CELL; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CELL TRANSPLANTATION; CONTROLLED STUDY; GENE EXPRESSION; GENE LOCUS; HEMATOPOIETIC CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SENESCENCE; STRAIN DIFFERENCE;

AGING; ANIMALS; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; CELL AGING; CELL DIVISION; CELLS, CULTURED; CROSSES, GENETIC; ERYTHROCYTES; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, DOMINANT; HEMATOPOIETIC STEM CELLS; KILLER CELLS, NATURAL; LINKAGE (GENETICS); LOD SCORE; LYMPHOCYTE DEPLETION; LYMPHOCYTES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, INBRED DBA; PHYSICAL CHROMOSOME MAPPING; SPECIES SPECIFICITY;

EID: 0034008968     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-472X(99)00157-5     Document Type: Article

References (42)

1. Hayflick L. The limited in vitro lifetime of human diploid cell strains. Exp Cell Res. 37:1965;614.
2. Goldstein S. Replicative senescence. the human fibroblast comes of age Science. 249:1990;1129.
3. Smith J.R., Pereira-Smith O.M. Replicative senescence. implications for in vivo aging and tumor suppression Science. 273:1996;63.
4. Dimii G.P., Lee X., Basile G., Acosta M., Scott G., Roskelley C., Medrano E.E., Linskens M., Rubelj 1 Pereira-Smith O.M., Peaccke M., Campisi J. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci U S A. 92:1995;9363.
5. Farrar J.J., Loughman B.E., Nordin A.A. Lymphopoietic potential of bone marrow cells from aged mice. comparison of the cellular constituents of bone marrow from young and aged mice J Immunol. 112:1974;1244.
6. Harrison D.E. Defective erythropoietic responses of aged mice not improved by young marrow. J Gerontol. 30:1975;286.
7. Albright J.W., Makinodan T. Decline in the growth potential of spleen-colonizing bone marrow cells of long-lived mice. J Exp Med. 144:1976;1204.
8. Ogden D.A., Micklem H.S. The fate of serially transplanted bone marrow cell populations from young and old donors. Transplantation. 22:1976;287.
9. Tyan M.L. Age-related decrease in mouse T-cell progenitors. J Immunol. 118:1977;846.
10. Hellman S., Botnick L.E., Hannon E.C., Vigneulle R.M. Proliferative capacity of muiine hematopoietic stem cells. Proc Natl Acad Sci U S A. 75:1978;490.
11. Gozes Y., Umiel T., Trainin N. Selective decline in differentiating capacity of immunohemopoietic stem cells with aging. Mech Ageing Dev. 18:1982;251.
12. Harrison D.E. Mouse erythropoietic stem cell lines function normally 100 months. loss related to number of transplantations Mech Ageing Dev. 9:1979;427.
13. Van Zant G., Eldridge P.W., Behringer R.R., Dewey M.J. Genetic control of hematopoietic kinetics revealed by analyses of allophenic mice and stem cell suicide. Cell. 35:1983;639.
14. Van Zant G., Holland B.P., Eldridge P.W., Chen J.J. Genotype-restricted growth and aging patterns in hematopoietic stem cell populations of allophenic mice. J Exp Med. 171:1990;1547.
15. Harrison D.E., Astle C.M., Stone M. Numbers and functions of transplantable primitive immunohematopoietic stem cells. Effects of age. J Immunol. 142:1989;3833.
16. Harrison D.E., Jordan C.T., Zhong R.K., Astle C.M. Primitive hemopoietic stem cells. direct assay of most productive populations by competitive repopulation with simple binomial, correlation and covariance calculations Exp Hematol. 21:1993;206.
17. Morrison S.J., Wandyez A.M., Akashi K., Globerson A., Weissman I.L. The aging of hematopoietic stem cells. Nat Med. 2:1996;1011.
18. de Haan G., Van Zant G. Intrinsic and extrinsic control of hemopoietic stem cell numbers. mapping of a stem cell gene J Exp Med. 186:1997;529.
19. de Haan G., Nijhof W., Van Zant G. Mouse strain-dependent changes in frequency and proliferation of hematopoietic stem cells during aging. correlation between lifespan and cycling activity Blood. 89:1997;1543.
20. Osawa M., Hanada K., Hamada H., Nakauchi H. Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science. 273:1996;242.
21. Hirokawa K., Kubo S., Utsuyama M., Kurashima C., Sado T. Age-related change in the potential of bone marrow cells to repopulate the thymus and splenic T cells in mice. Cell Immunol. 100:1986;443.
22. Harrison D.E. Long-term erythropoietic repopulating ability of old, young, and fetal stem cells. J Exp Med. 157:1983;1496.
23. Van Zant G., Thompson B.P., Chen J.J. Differentiation of chimeric bone marrow in vivo reveals genotype-restricted contributions to hematopoiesis. Exp Hematol. 19:1991;941.
24. Van Zant G., Scott Micus K., Thompson B.P., Fleischman R.A., Perkins S. Stem cell quiescence/activation is reversible by serial transplantation and is independent of stromal cell genotype in mouse aggregation chimeras. Exp Hematol. 20:1992;470.
25. Phillips R.L., Reinhart A.J., Van Zant G. Genetic control of murine hematopoietic stem cell pool sizes and cycling kinetics. Proc Natl Acad Sci U S A. 89:1992;11607.
26. Chen J., Astle C.M., Harrison D.E. Development and aging of primitive hematopoietic stem cells in BALB/cBy mice. Exp Hematol. 27:1999;928.
27. Lansdorp P.M., Dragowska W., Mayani H. Onto geny -related changes in proliferative potential of human hematopoietic cells. J Exp Med. 178:1993;787.
28. Handbook on genetically standardized JAX mice. 1997;The Jackson Laboratory, Bar Harbor, ME.
29. SAS Institute Inc. (1998) EVEP Statistics and Graphics Guide, Version 3. Cary, NC.
30. Mouse Genome Informatics (1999): Mouse Genome Database (MGD). Bar Harbor, Maine: The Jackson Laboratory.
31. Muller-Sieburg C.E., Riblet R. Genetic control of the frequency of hematopoietic stem cells in mice. mapping of a canadidate locus to chromosome 1 J Exp Med. 183:1996;1141.
32. Harrison D.E., Stone M., Astle C.M. Effects of transplantation on the primitive immunohematopoietic stem cell. J Exp Med. 172:1990;431.
33. Bailey DW (1981) Recombinant inbred strains and bilineal congenic strains. In: Foster BL, Small JD, Fox JG. The mouse in biomedical research, vol. I. New York: Academic Press Inc.).
34. Taylor B.A. Recombinant Inbred strains. Lyon M.T., Rastan S., Brown S.D.M. Genetic variants and strains of the laboratory mouse, vol. 2. 1996;Oxford University Press, New York.
35. Lander E.S., Schork N.J. Genetic dissection of complex traits. Science. 265:1994;2037.
36. Lander E., Kruglyak L. Genetic dissection of complex traits. guidelines for interpreting and reporting linkage results Nat-Genet. 11:1995;241.
37. Zhong R.K., Astle C.M., Harrison D.E. Distinct developmental patterns of short-term and long-term functioning lymphoid and myeloid precursors defined by competitive limiting dilution analysis in vivo. J Immunol. 157:1996;138.
38. Spangrude G.J., Brooks D.M., Tumas D.B. Long-term repopulation of irradiated mice with limiting numbers of purified hematopoietic stem cells. in vivo expansion of stem cell phenotype but not function Blood. 85:1995;1006.
39. Rebel V.I., Dragowska W., Eaves C.J., Humphries R.K., Lansdorp P.M. Amplification of Sca-l+ Lin- WGA+ cells in serum-free cultures containing steel factor, interleukin-6, and erythropoietin with maintenance of cells with long-term in vivo reconstituting potential. Blood. 83:1994;128.
40. Pereira-Smith O.M. Genetic theories on aging. Aging (Milano). 9:1997;429.
41. Lansdorp P.M., Dragowska W., Thomas T.E., Little M.T., Mayani H. Age-related decline in proliferative potential of purified stem cell candidates. Blood Cells. 20:1994;376. [see comments].
42. de Haan G., Van Zant G. Dynamic changes in mouse hematopoietic stem cell numbers during aging. Blood. 93:1999;3294.