-
1
-
-
40849083460
-
Non-alcoholic fatty liver disease: The mist gradually clears
-
de Alwis, N. M., and C. P. Day. 2008. Non-alcoholic fatty liver disease: the mist gradually clears. J. Hepatol. 48 ( Suppl 1 ): S104-S112.
-
(2008)
J. Hepatol.
, vol.48
, Issue.SUPPL. 1
-
-
De Alwis, N.M.1
Day, C.P.2
-
2
-
-
66349125337
-
Nonalcoholic fatty liver disease
-
Erickson, S. K. 2009. Nonalcoholic fatty liver disease. J. Lipid Res. 50 ( Suppl ): S412-S416.
-
(2009)
J. Lipid Res.
, vol.50
, Issue.SUPPL.
-
-
Erickson, S.K.1
-
3
-
-
65449156905
-
NAFLD as a r isk factor for the development of diabetes and the metabolic syndrome: An eleven-year follow-up study
-
Adams, L. A., O. R. Waters, M. W. Knuiman, R. R. Elliott, and J. K. Olynyk. 2009. NAFLD as a r isk factor for the development of diabetes and the metabolic syndrome: an eleven-year follow-up study. Am. J. Gastroenterol. 104: 861-867.
-
(2009)
Am. J. Gastroenterol.
, vol.104
, pp. 861-867
-
-
Adams, L.A.1
Waters, O.R.2
Knuiman, M.W.3
Elliott, R.R.4
Olynyk, J.K.5
-
4
-
-
17444417085
-
Nonalcoholic fatty liver disease
-
Adams, L. A., P. Angulo, and K. D. Lindor. 2005. Nonalcoholic fatty liver disease. CMAJ. 172: 899-905.
-
(2005)
CMAJ.
, vol.172
, pp. 899-905
-
-
Adams, L.A.1
Angulo, P.2
Lindor, K.D.3
-
5
-
-
0037129380
-
Nonalcoholic fatty liver disease
-
Angulo, P. 2002. Nonalcoholic fatty liver disease. N. Engl. J. Med. 346: 1221-1231.
-
(2002)
N. Engl. J. Med.
, vol.346
, pp. 1221-1231
-
-
Angulo, P.1
-
6
-
-
30044431801
-
From fat to infl ammation
-
Day, C. P. 2006. From fat to infl ammation. Gastroenterology. 130: 207-210.
-
(2006)
Gastroenterology.
, vol.130
, pp. 207-210
-
-
Day, C.P.1
-
7
-
-
56649094325
-
Molecular mechanisms of lipotoxicity in nonalcoholic fatty liver disease
-
Malhi, H., and G. J. Gores. 2008. Molecular mechanisms of lipotoxicity in nonalcoholic fatty liver disease. Semin. Liver Dis. 28: 360-369.
-
(2008)
Semin. Liver Dis.
, vol.28
, pp. 360-369
-
-
Malhi, H.1
Gores, G.J.2
-
8
-
-
57649214103
-
Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD
-
Musso, G., R. Gambino, and M. Cassader. 2009. Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD). Prog. Lipid Res. 48: 1-26.
-
(2009)
Prog. Lipid Res.
, vol.48
, pp. 1-26
-
-
Musso, G.1
Gambino, R.2
Cassader, M.3
-
9
-
-
51449106076
-
ChREBP: A glucose-activated transcription factor involved in the development of metabolic syndrome
-
Iizuka, K., and Y. Horikawa. 2008. ChREBP: a glucose-activated transcription factor involved in the development of metabolic syndrome. Endocr. J. 55: 617-624.
-
(2008)
Endocr. J.
, vol.55
, pp. 617-624
-
-
Iizuka, K.1
Horikawa, Y.2
-
10
-
-
33644652183
-
Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasis
-
Lefebvre, P., G. Chinetti, J. C. Fruchart, and B. Staels. 2006. Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasis. J. Clin. Invest. 116: 571-580.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 571-580
-
-
Lefebvre, P.1
Chinetti, G.2
Fruchart, J.C.3
Staels, B.4
-
11
-
-
66349099340
-
Fatty acid metabo lism: Target for metabolic syndrome
-
Wakil, S. J., and L. A. Abu-Elheiga. 2009. Fatty acid metabo lism: target for metabolic syndrome. J. Lipid Res. 50 ( Suppl ): S138-S143.
-
(2009)
J. Lipid Res.
, vol.50
, Issue.SUPPL.
-
-
Wakil, S.J.1
Abu-Elheiga, L.A.2
-
12
-
-
0020624753
-
Observations on the affi nity for carnitine, and malonyl-CoA sensitivity, of carnitine palmitoyltransferase i in animal and human tissues
-
McGarry, J. D., S. E. Mills, C. S. Long, and D. W. Foster. 1983. Observations on the affi nity for carnitine, and malonyl-CoA sensitivity, of carnitine palmitoyltransferase I in animal and human tissues. Demonstration of the presence of malonyl-CoA in nonhepatic tissues of the rat. Bio chem. J. 214: 21-28.
-
(1983)
Demonstration of the Presence of Malonyl-CoA in Nonhepatic Tissues of the Rat. Bio Chem. J.
, vol.214
, pp. 21-28
-
-
McGarry, J.D.1
Mills, S.E.2
Long, C.S.3
Foster, D.W.4
-
13
-
-
73149094543
-
The plasma lipi domic signature of nonalcoholic steatohepatitis
-
Puri, P., M. M. Wiest, O. Cheung, F. Mirshahi, C. Sargeant, H. K. Min, M. J. Contos, R. K. Sterling, M. Fuchs, H. Zhou, et al. 2009. The plasma lipi domic signature of nonalcoholic steatohepatitis. Hepatology. 50: 1827-1838.
-
(2009)
Hepatology
, vol.50
, pp. 1827-1838
-
-
Puri, P.1
Wiest, M.M.2
Cheung, O.3
Mirshahi, F.4
Sargeant, C.5
Min, H.K.6
Contos, M.J.7
Sterling, R.K.8
Fuchs, M.9
Zhou, H.10
-
14
-
-
36349024819
-
A lipidomic analysis of nonalcoholic fatty liver disease
-
Puri, P., R. A. Baillie, M. M. Wiest, F. Mirshahi, J. Choudhury, O. Cheung, C. Sargeant, M. J. Contos, and A. J. Sanyal. 2007. A lipidomic analysis of nonalcoholic fatty liver disease. Hepatology. 46: 1081-1090.
-
(2007)
Hepatology
, vol.46
, pp. 1081-1090
-
-
Puri, P.1
Baillie, R.A.2
Wiest, M.M.3
Mirshahi, F.4
Choudhury, J.5
Cheung, O.6
Sargeant, C.7
Contos, M.J.8
Sanyal, A.J.9
-
15
-
-
79951682747
-
Pathogenesis of lipid metabolism disorder in hepatitis C: Polyunsaturated fatty acids counteract lipid alterations induced by the core protein
-
Miyoshi, H., K. Moriya, T. Tsutsumi, S. Shinzawa, H. Fujie, Y. Shintani, H. Fujinaga, K. Goto, T. Todoroki, T. Suzuki, et al. 2011. Pathogenesis of lipid metabolism disorder in hepatitis C: polyunsaturated fatty acids counteract lipid alterations induced by the core protein. J. Hepatol. 54: 432-43 8.
-
(2011)
J. Hepatol
, vol.54
, pp. 432-438
-
-
Miyoshi, H.1
Moriya, K.2
Tsutsumi, T.3
Shinzawa, S.4
Fujie, H.5
Shintani, Y.6
Fujinaga, H.7
Goto, K.8
Todoroki, T.9
Suzuki, T.10
-
16
-
-
34247637220
-
Hepatitis B virus X protein induces hepatic steatosis via tr anscriptional activation of SREBP1 and PPARgamma
-
Kim, K. H., H. J. Shin, K. Kim, H. M. Choi, S. H. Rhee, H. B. Moon, H. H. Kim, U. S. Yang, D. Y. Yu, and J. Cheong. 2007. Hepatitis B virus X protein induces hepatic steatosis via tr anscriptional activation of SREBP1 and PPARgamma. Gastroenterology. 132: 1955-1967.
-
(2007)
Gastroenterology
, vol.132
, pp. 1955-1967
-
-
Kim, K.H.1
Shin, H.J.2
Kim, K.3
Choi, H.M.4
Rhee, S.H.5
Moon, H.B.6
Kim, H.H.7
Yang, U.S.8
Yu, D.Y.9
Cheong, J.10
-
17
-
-
34948904815
-
Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance
-
Matsuzaka, T., H. Shimano, N. Yahagi, T. Kato, A. Atsumi, T. Yamamoto, N. Inoue, M. Ishikawa, S. Okada, N. Ishigaki, et al. 2007. Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance. Nat. Med. 13: 1193-1202.
-
(2007)
Nat. Med.
, vol.13
, pp. 1193-1202
-
-
Matsuzaka, T.1
Shimano, H.2
Yahagi, N.3
Kato, T.4
Atsumi, A.5
Yamamoto, T.6
Inoue, N.7
Ishikawa, M.8
Okada, S.9
Ishigaki, N.10
-
18
-
-
39549097750
-
Mouse Elovl-6 promoter is an SREBP target
-
Kumadaki, S., T. Matsuzaka, T. Kato, N. Yahagi, T. Yamamoto, S. Okada, K. Kobayashi, A. Takahashi, S. Yatoh, H. Suzuki, et al. 2008. Mouse Elovl-6 promoter is an SREBP target. Biochem. Biophys. Res. Commun. 368: 261-266.
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.368
, pp. 261-266
-
-
Kumadaki, S.1
Matsuzaka, T.2
Kato, T.3
Yahagi, N.4
Yamamoto, T.5
Okada, S.6
Kobayashi, K.7
Takahashi, A.8
Yatoh, S.9
Suzuki, H.10
-
19
-
-
84863804630
-
Tsc2, a positional candidate gene under lying a quantitative trait locus for hepatic steatosis
-
Wang, C. Y., D. S. Stapleton, K. L. Schueler, M. E. Rabaglia, A. T. Oler, M. P. Keller, C. M. Kendziorski, K. W. Broman, B. S. Yandell, E. E. Schadt, et al. 2012. Tsc2, a positional candidate gene under lying a quantitative trait locus for hepatic steatosis. J. Lipid Res. 53: 1493-1501.
-
(2012)
J. Lipid Res.
, vol.53
, pp. 1493-1501
-
-
Wang, C.Y.1
Stapleton, D.S.2
Schueler, K.L.3
Rabaglia, M.E.4
Oler, A.T.5
Keller, M.P.6
Kendziorski, C.M.7
Broman, K.W.8
Yandell, B.S.9
Schadt, E.E.10
-
20
-
-
84870541988
-
Elovl6 promotes nonalcoholic steatohepatitis
-
Matsuzaka, T., A. Atsumi, R. Matsumori, T. Nie, H. Shinozaki, N. Suzuki-Kemuriyama, M. Kuba, Y. Nakagawa , K. Ishii, M. Shimada, et al. 2012. Elovl6 promotes nonalcoholic steatohepatitis. Hepatology. 56: 2199-2208.
-
(2012)
Hepatology.
, vol.56
, pp. 2199-2208
-
-
Matsuzaka, T.1
Atsumi, A.2
Matsumori, R.3
Nie, T.4
Shinozaki, H.5
Suzuki-Kemuriyama, N.6
Kuba, M.7
Nakagawa, Y.8
Ishii, K.9
Shimada, M.10
-
21
-
-
84881454013
-
Proteomic and lipidomic signatures of lipid metabolism in NASH-associated hepatocellular carcinoma
-
Muir, K., A. Hazim, Y. He, M. Peyressatre, D. Y. Kim, X. Song, and L. Beretta. 2013. Proteomic and lipidomic signatures of lipid metabolism in NASH-associated hepatocellular carcinoma. Cancer Res. 73: 4722-4731.
-
(2013)
Cancer Res.
, vol.73
, pp. 4722-4731
-
-
Muir, K.1
Hazim, A.2
He, Y.3
Peyressatre, M.4
Kim, D.Y.5
Song, X.6
Beretta, L.7
-
22
-
-
84898732247
-
Fatty acid elongation in non-alcoholic steatohepatitis and hepatocellular carcinoma
-
Kessler, S. M., Y. Simon, K. Gemperlein, K. Gianmoena, C. Cadenas, V. Zimmer, J. Pokorny, A. Barghash, V. Helms, N. van Rooijen, et al. 2014. Fatty acid elongation in non-alcoholic steatohepatitis and hepatocellular carcinoma. Int. J. Mol. Sci. 15: 5762-5773.
-
(2014)
Int. J. Mol. Sci.
, vol.15
, pp. 5762-5773
-
-
Kessler, S.M.1
Simon, Y.2
Gemperlein, K.3
Gianmoena, K.4
Cadenas, C.5
Zimmer, V.6
Pokorny, J.7
Barghash, A.8
Helms, V.9
Van Rooijen, N.10
-
23
-
-
84898766063
-
Lipid metabolism signatures in NASH-associated HCC-letter
-
Epub ahead of print. April 28 doi:10.115 8/0008-5472.CAN-13-2852
-
Kessler, S. M., S. Laggai, A. Barghash, V. Helms, and A. K. Kiemer. Lipid metabolism signatures in NASH-associated HCC-letter. Cancer Res. Epub ahead of print. April 28, 2014; doi:10.115 8/0008-5472.CAN-13-2852.
-
(2014)
Cancer Res
-
-
Kessler, S.M.1
Laggai, S.2
Barghash, A.3
Helms, V.4
Kiemer, A.K.5
-
24
-
-
79954648698
-
Overexpression of the IGF2-m RNA binding protein p62 in transgenic mice induces a steatotic phenotype
-
Tybl, E., F. D. Shi, S. M. Kessler, S. Tierling, J. Walter, R. M. Bohle, S. Wieland, J. Zhang, E. M. Tan, and A. K. Kiemer. 2011. Overexpression of the IGF2-m RNA binding protein p62 in transgenic mice induces a steatotic phenotype. J. Hepatol. 54: 994-1001.
-
(2011)
J. Hepatol.
, vol.54
, pp. 994-1001
-
-
Tybl, E.1
Shi, F.D.2
Kessler, S.M.3
Tierling, S.4
Walter, J.5
Bohle, R.M.6
Wieland, S.7
Zhang, J.8
Tan, E.M.9
Kiemer, A.K.10
-
25
-
-
84897969932
-
The insulin-like growth factor 2 (IGF2) mRNA-binding protein p62/IGF2BP2-2 as a promoter of NAFLD and HCC
-
Simon, Y., S. M. Kessler, R. M. Bohle, J. Haybaeck, and A. K. Kiemer. 2014. The insulin-like growth factor 2 (IGF2) mRNA-binding protein p62/IGF2BP2-2 as a promoter of NAFLD and HCC Gut. 63: 861-863.
-
(2014)
Gut.
, vol.63
, pp. 861-863
-
-
Simon, Y.1
Kessler, S.M.2
Bohle, R.M.3
Haybaeck, J.4
Kiemer, A.K.5
-
26
-
-
84887323587
-
Rapid chromatographic method to decipher distinct alterations in lipid classes in NAFLD/NASH
-
Laggai, S., Y. Simon, T. Ranssweiler, A. K. Kiemer, and S. M. Kessler. 2013. Rapid chromatographic method to decipher distinct alterations in lipid classes in NAFLD/NASH. World J. Hepatol. 5: 558-567.
-
(2013)
World J. Hepatol.
, vol.5
, pp. 558-567
-
-
Laggai, S.1
Simon, Y.2
Ranssweiler, T.3
Kiemer, A.K.4
Kessler, S.M.5
-
27
-
-
84874095808
-
IGF2 mRNA binding protein p62/IMP2-2 in hepatocellular carcinoma: Antiapoptotic action is independent of IGF2/PI3K signaling. Am. J. Physiol. Gastrointest
-
Kessler, S. M., J. Pokorny, V. Zimmer, S. Laggai, F. Lammert, R. M. Bohle, and A. K. Kiemer. 2013. IGF2 mRNA binding protein p62/IMP2-2 in hepatocellular carcinoma: antiapoptotic action is independent of IGF2/PI3K signaling. Am. J. Physiol. Gastrointest. Liver Physiol. 304: G328-G336.
-
(2013)
Liver Physiol.
, vol.304
-
-
Kessler, S.M.1
Pokorny, J.2
Zimmer, V.3
Laggai, S.4
Lammert, F.5
Bohle, R.M.6
Kiemer, A.K.7
-
28
-
-
17144420518
-
P62 Expression in primary carcinomas of the digestive system
-
Qian, H. L., X. X. Peng, S. H. Chen, H. M. Ye, and J. H. Qiu. 2005. p62 Expression in primary carcinomas of the digestive system. World J. Gastroenterol. 11: 1788-1792.
-
(2005)
World J. Gastroenterol.
, vol.11
, pp. 1788-1792
-
-
Qian, H.L.1
Peng, X.X.2
Chen, S.H.3
Ye, H.M.4
Qiu, J.H.5
-
29
-
-
1542509671
-
Autoantibodies to IGF-II mRNA binding protein p62 and overexpression of p62 in human hepatocellular carcinoma
-
Zhang, J., and E. K. Chan. 2002. Autoantibodies to IGF-II mRNA binding protein p62 and overexpression of p62 in human hepatocellular carcinoma. Autoimmun. Rev. 1: 146-153.
-
(2002)
Autoimmun. Rev
, vol.1
, pp. 146-153
-
-
Zhang, J.1
Chan, E.K.2
-
30
-
-
0033526101
-
A novel cytoplasmic protein with RNA-binding motifs is an autoantigen in human hepatocellular carcinoma
-
Zhang, J. Y., E. K. Chan, X. X. Peng, and E. M. Tan. 1999. A novel cytoplasmic protein with RNA-binding motifs is an autoantigen in human hepatocellular carcinoma. J. Exp. Med. 189: 1101-1110.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1101-1110
-
-
Zhang, J.Y.1
Chan, E.K.2
Peng, X.X.3
Tan, E.M.4
-
31
-
-
77949875878
-
IGF activation in a molecular subclass of hepatocellular carcinoma and pre-clinical effi c acy of IGF-1R blockage
-
Tovar, V., C. Alsinet, A. Villanueva, Y. Hoshida, D. Y. Chiang, M. Sole, S. Thung, S. Moyano, S. Toffanin, B. Minguez, et al. 2010. IGF activation in a molecular subclass of hepatocellular carcinoma and pre-clinical effi c acy of IGF-1R blockage. J. Hepatol. 52: 550-559.
-
(2010)
J. Hepatol.
, vol.52
, pp. 550-559
-
-
Tovar, V.1
Alsinet, C.2
Villanueva, A.3
Hoshida, Y.4
Chiang, D.Y.5
Sole, M.6
Thung, S.7
Moyano, S.8
Toffanin, S.9
Minguez, B.10
-
32
-
-
30944453514
-
Exploration of global gene expression in human liver steatosis by high-density oligonucleotide microarray
-
Chiappini, F., A. Barrier, R. Saffroy, M. C. Domart, N. Dagues, D. Azoulay, M. Sebagh, B. Franc, S. Chevalier, B. Debuire, et al. 2006. Exploration of global gene expression in human liver steatosis by high-density oligonucleotide microarray. Lab. Invest. 86: 154-165.
-
(2006)
Lab. Invest.
, vol.86
, pp. 154-165
-
-
Chiappini, F.1
Barrier, A.2
Saffroy, R.3
Domart, M.C.4
Dagues, N.5
Azoulay, D.6
Sebagh, M.7
Franc, B.8
Chevalier, S.9
Debuire, B.10
-
33
-
-
70449657762
-
IGF2 mRNA-binding protein 2: Biological function and putative role in type 2 diabetes
-
Christiansen J.,A. M. Kolte,T. Hansen,F. C. Nielsen,2009. IGF2 mRNA-binding protein 2: biological function and putative role in type 2 diabetes. J. Mol. Endocrinol.,43, 187-195.
-
(2009)
J. Mol. Endocrinol.
, vol.43
, pp. 187-195
-
-
Christiansen, J.1
Kolte, A.M.2
Hansen, T.3
Nielsen, F.C.4
-
34
-
-
84870856707
-
An HMGA2-IGF2BP2 axis regulates myoblast proliferation and myogenesis
-
Li, Z., J. A. Gilbert, Y. Zhang, M. Zhang, Q. Qiu, K. Ram anujan, T. Shavlakadze, J. K. Eash, A. Scaramozza, M. M. Goddeeris, et al. 2012. An HMGA2-IGF2BP2 axis regulates myoblast proliferation and myogenesis. Dev. Cell. 23: 1176-1188.
-
(2012)
Dev. Cell.
, vol.23
, pp. 1176-1188
-
-
Li, Z.1
Gilbert, J.A.2
Zhang, Y.3
Zhang, M.4
Qiu, Q.5
Ram Anujan, K.6
Shavlakadze, T.7
Eash, J.K.8
Scaramozza, A.9
Goddeeris, M.M.10
-
35
-
-
73549090090
-
Kupffer cell activation is a causal factor for hepatic insulin resistance
-
Lanthier, N., O. Molendi-Coste, Y. Horsmans, N. van Rooijen, P. D. Cani, and I. A. Leclercq. 2010. Kupffer cell activation is a causal factor for hepatic insulin resistance. Am. J. Physiol. Gastrointest. Liver Physiol. 298: G107-G116.
-
(2010)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.298
-
-
Lanthier, N.1
Molendi-Coste, O.2
Horsmans, Y.3
Van Rooijen, N.4
Cani, P.D.5
Leclercq, I.A.6
-
36
-
-
33748761152
-
3-Hydroxy-3-methylglutaryl-coenzyme A (CoA) synthase is involved in biosynthesis of isovaleryl-CoA in the myxobacterium Myxococcus xanthus during fruiting body formation
-
Bode, H. B., M. W. Ring, G. Schwar, R. M. Kroppenstedt, D. Kaiser, and R. Muller. 2006. 3-Hydroxy-3-methylglutaryl-coenzyme A (CoA) synthase is involved in biosynthesis of isovaleryl-CoA in the myxobacterium Myxococcus xanthus during fruiting body formation. J. Bacteriol. 188 : 6524-6528.
-
(2006)
J. Bacteriol.
, vol.188
, pp. 6524-6528
-
-
Bode, H.B.1
Ring, M.W.2
Schwar, G.3
Kroppenstedt, R.M.4
Kaiser, D.5
Muller, R.6
-
37
-
-
63449093275
-
Attenuated activation of macrophage TLR9 by DNA fr om virulent mycobacteria
-
Kiemer, A. K., R. H. Senaratne, J. Hoppstadter, B. Diesel, L. W. Riley, K. Tabeta, S. Bauer, B. Beutler, and B. L. Zuraw. 2009. Attenuated activation of macrophage TLR9 by DNA fr om virulent mycobacteria. J. Innate Immun. 1: 29-45.
-
(2009)
J. Innate Immun.
, vol.1
, pp. 29-45
-
-
Kiemer, A.K.1
Senaratne, R.H.2
Hoppstadter, J.3
Diesel, B.4
Riley, L.W.5
Tabeta, K.6
Bauer, S.7
Beutler, B.8
Zuraw, B.L.9
-
38
-
-
0034283596
-
Insulin effects on sterol regulatory-elementbi nding protein-1c (SREBP-1c) transcriptional activity in rat hepatocytes
-
Azzout-Marniche, D., D. Becard, C. Guichard, M. Foretz, P. Ferre, and F. Foufelle. 2000. Insulin effects on sterol regulatory-elementbi nding protein-1c (SREBP-1c) transcriptional activity in rat hepatocytes. Biochem. J. 350: 389-393.
-
(2000)
Biochem. J.
, vol.350
, pp. 389-393
-
-
Azzout-Marniche, D.1
Becard, D.2
Guichard, C.3
Foretz, M.4
Ferre, P.5
Foufelle, F.6
-
39
-
-
79953042637
-
Down-regulation of hepatic ApoB100 expression during hot season in transition dairy cows
-
Basirico, L., P. Morera, N. Lacetera, B. Ronchi, A. Nardone, and U. Bernabucci. 2011. Down-regulation of hepatic ApoB100 expression during hot season in transition dairy cows. Livest. Sci. 137: 49-57.
-
(2011)
Livest. Sci.
, vol.137
, pp. 49-57
-
-
Basirico, L.1
Morera, P.2
Lacetera, N.3
Ronchi, B.4
Nardone, A.5
Bernabucci, U.6
-
40
-
-
0034856833
-
Aberrant expression of fetal RNA-binding protein p62 in liver cancer and liver cirrho sis
-
Lu, M., R. M. Nakamura, E. D. Dent, J. Y. Zhang, F. C. Nielsen, J. Christiansen, E. K. Chan, and E. M. Tan. 2001. Aberrant expression of fetal RNA-binding protein p62 in liver cancer and liver cirrho sis. Am. J. Pathol. 159: 945-953.
-
(2001)
Am. J. Pathol.
, vol.159
, pp. 945-953
-
-
Lu, M.1
Nakamura, R.M.2
Dent, E.D.3
Zhang, J.Y.4
Nielsen, F.C.5
Christiansen, J.6
Chan, E.K.7
Tan, E.M.8
-
41
-
-
79958863581
-
Distinct regulation of adiponutrin/PNPLA3 gene expression by the transcription factors ChREBP and SREBP1c in mouse and human hepatocytes
-
Dubuquoy, C., C. Robichon, F. Lasnier, C. Langlois, I. Dugail, F. Foufelle, J. Girard, A. F. Burnol, C. Postic, and M. Moldes. 2011. Distinct regulation of adiponutrin/PNPLA3 gene expression by the transcription factors ChREBP and SREBP1c in mouse and human hepatocytes. J. Hepatol. 55: 145-153.
-
(2011)
J. Hepatol.
, vol.55
, pp. 145-153
-
-
Dubuquoy, C.1
Robichon, C.2
Lasnier, F.3
Langlois, C.4
Dugail, I.5
Foufelle, F.6
Girard, J.7
Burnol, A.F.8
Postic, C.9
Moldes, M.10
-
42
-
-
84862833343
-
Endoplasmic reticulum stressinduced JNK activation is a critical event leading to mitochondriamediated cell death caused by-lapachone treatment
-
Lee, H., M. T. Park, B. H. Choi, E. T. Oh, M. J. Song, J. Lee, C. Kim, B. U. Lim, and H. J. Park. 2011. Endoplasmic reticulum stressinduced JNK activation is a critical event leading to mitochondriamediated cell death caused by-lapachone treatment. PLoS ONE. 6: e21533.
-
(2011)
PLoS ONE.
, vol.6
-
-
Lee, H.1
Park, M.T.2
Choi, B.H.3
Oh, E.T.4
Song, M.J.5
Lee, J.6
Kim, C.7
Lim, B.U.8
Park, H.J.9
-
43
-
-
67349210047
-
Unsaturated fatty acids promote hepatoma proliferation and progression through downregula tion of the tumor suppressor PTEN
-
Vinciguerra, M., F. Carrozzino, M. Peyrou, S. Carlone, R. Montesano, R. Benelli, and M. Foti. 2009. Unsaturated fatty acids promote hepatoma proliferation and progression through downregula tion of the tumor suppressor PTEN. J. Hepatol. 50: 1132-1141.
-
(2009)
J. Hepatol.
, vol.50
, pp. 1132-1141
-
-
Vinciguerra, M.1
Carrozzino, F.2
Peyrou, M.3
Carlone, S.4
Montesano, R.5
Benelli, R.6
Foti, M.7
-
44
-
-
84871180269
-
Elovl5 regulates the mTORC2-Akt-FOXO1 pathway by controlling hepatic cis-vaccenic acid synthesis in diet-induced obese mice
-
Tripathy, S., and D. B. Jump. 2013. Elovl5 regulates the mTORC2-Akt-FOXO1 pathway by controlling hepatic cis-vaccenic acid synthesis in diet-induced obese mice. J. Lipid Res. 54: 71-84.
-
(2013)
J. Lipid Res.
, vol.54
, pp. 71-84
-
-
Tripathy, S.1
Jump, D.B.2
-
45
-
-
40749128979
-
IGF2: Epigenetic regulation and role in development and disease
-
Chao, W., and P. A. D Amore. 2008. IGF2: epigenetic regulation and role in development and disease. Cytokine Growth Factor Rev. 19: 111-120.
-
(2008)
Cytokine Growth Factor Rev.
, vol.19
, pp. 111-120
-
-
Chao, W.1
Damore, P.A.2
-
46
-
-
3843061127
-
Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver
-
Chen, G., G. Liang, J. Ou, J. L. Goldstein, and M. S. Brown. 2004. Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in live r. Proc. Natl. Acad. Sci. USA. 101: 11245-11250.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 11245-11250
-
-
Chen, G.1
Liang, G.2
Ou, J.3
Goldstein, J.L.4
Brown, M.S.5
-
47
-
-
40549135297
-
Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: Lessons from genetically engineered mice
-
Postic, C., and J. Girard. 2008. Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice. J. Clin. Invest. 118: 829-838.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 829-838
-
-
Postic, C.1
Girard, J.2
-
48
-
-
33749370739
-
Liver-specifi c inhibition of Ch REBP improves hepatic steatosis and insulin resistance in ob/ob mice
-
Dentin, R., F. Benhamed, I. Hainault, V. Fauveau, F. Foufelle, J. R. Dyck, J. Girard, and C. Postic. 2006. Liver-specifi c inhibition of Ch REBP improves hepatic steatosis and insulin resistance in ob/ob mice. Diabetes. 55: 2159-2170.
-
(2006)
Diabetes.
, vol.55
, pp. 2159-2170
-
-
Dentin, R.1
Benhamed, F.2
Hainault, I.3
Fauveau, V.4
Foufelle, F.5
Dyck, J.R.6
Girard, J.7
Postic, C.8
-
49
-
-
34548392209
-
Modulation of sterol regulatory element binding proteins (SREBPs) as potential treatments for non-alcoholic fatty liver disease (NAFLD)
-
Ahmed, M. H., and C. D. Byrne. 2007. Modulation of sterol regulatory element binding proteins (SREBPs) as potential treatments for non-alcoholic fatty liver disease (NAFLD). Drug Discov. Today. 12: 740-747.
-
(2007)
Drug Discov. Today.
, vol.12
, pp. 740-747
-
-
Ahmed, M.H.1
Byrne, C.D.2
-
50
-
-
0033570119
-
Increased levels of nuclear SREBP-1c associated with fatty livers in two mouse models of diabetes mellitus
-
Shimomura, I., Y. Bashmakov, and J. D. Horton. 1999. Increased levels of nuclear SREBP-1c associated with fatty livers in two mouse models of diabetes mellitus. J. Biol. Chem. 274: 30028-30032.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 30028-30032
-
-
Shimomura, I.1
Bashmakov, Y.2
Horton, J.D.3
-
51
-
-
34347406521
-
SREBP-1c transcription factor and lipid homeostasis: Clinical perspective
-
Ferré, P., and F. Foufelle. 2007. SREBP-1c transcription factor and lipid homeostasis: clinical perspective. Horm. Res. 68: 72-82.
-
(2007)
Horm. Res.
, vol.68
, pp. 72-82
-
-
Ferré, P.1
Foufelle, F.2
-
52
-
-
78650043469
-
Inhibitory effect of LXR activation on cell proliferation and cell cycle progression through lipogenic activity
-
Kim, K. H., G. Y. Lee, J. I. Kim, M. Ham, J. Won Lee, and J. B. Kim. 2010. Inhibitory effect of LXR activation on cell proliferation and cell cycle progression through lipogenic activity. J. Lipid Res. 51: 3425-3433.
-
(2010)
J. Lipid Res.
, vol.51
, pp. 3425-3433
-
-
Kim, K.H.1
Lee, G.Y.2
Kim, J.I.3
Ham, M.4
Won Lee, J.5
Kim, J.B.6
-
53
-
-
84878687762
-
Inhibition of LXR - /SREBP-1c-mediated hepatic steatosis by Jiang-Zhi granule
-
Wang, M., S. Sun, T. Wu, L. Zhang, H. Song, W. Hao, P. Zheng, L. Xing, and G. Ji. 2013. Inhibition of LXR - /SREBP-1c-mediated hepatic steatosis by Jiang-Zhi granule. Evid. Based Complement. Alternat. Med. 2013: 584634.
-
(2013)
Evid. Based Complement. Alternat. Med.
, vol.2013
, pp. 584634
-
-
Wang, M.1
Sun, S.2
Wu, T.3
Zhang, L.4
Song, H.5
Hao, W.6
Zheng, P.7
Xing, L.8
Ji, G.9
-
54
-
-
0035047709
-
Identifi cation of liver X receptor-retinoid X recep tor as an activator of the sterol regulatory element-binding protein 1c gene promoter
-
Yoshikawa T.,H. Shimano,M. Amemiya-Kudo,N. Yahagi,A.H. Hasty,T. Matsuzaka,H. Okazaki,Y. Tamura,Y. Iizuka,K. Ohashi,et al,2001, Identifi cation of liver X receptor-retinoid X recep tor as an activator of the sterol regulatory element-binding protein 1c gene promoter. Mol. Cell. Biol.21, 2991-3000.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 2991-3000
-
-
Yoshikawa, T.1
Shimano, H.2
Amemiya-Kudo, M.3
Yahagi, N.4
Hasty, A.H.5
Matsuzaka, T.6
Okazaki, H.7
Tamura, Y.8
Iizuka, Y.9
Ohashi, K.10
-
55
-
-
0030961960
-
Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells
-
Shimomura, I., H. Shimano, J. D. Horton, J. L. Goldstein, and M. S. Brown. 1997. Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells. J. Clin. Invest. 99: 838-845.
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 838-845
-
-
Shimomura, I.1
Shimano, H.2
Horton, J.D.3
Goldstein, J.L.4
Brown, M.S.5
-
56
-
-
0035852770
-
Expression of sterol regulatory element-binding protein 1c (SREBP-1c) mRNA in rat hepatoma cells requires endogenous LXR ligands
-
DeBose-Boyd, R. A., J. Ou, J. L. Goldstein, and M. S. Brown. 2001. Expression of sterol regulatory element-binding protein 1c (SREBP-1c) mRNA in rat hepatoma cells requires endogenous LXR ligands. Proc. Natl. Acad. Sci. USA. 98: 1477-1482.
-
(2001)
Proc. Natl. Acad. Sci. USA.
, vol.98
, pp. 1477-1482
-
-
De Bose-Boyd, R.A.1
Ou, J.2
Goldstein, J.L.3
Brown, M.S.4
-
57
-
-
0034669025
-
Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors
-
Repa, J. J., G. Liang, J. Ou, Y. Bashmakov, J. M. Lobaccaro, I. Shimomura, B. Shan, M. S. Brown, J. L. Goldstein, and D. J. Mangelsdorf. 2000. Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta. Genes Dev. 14: 2819-2830.
-
(2000)
LXRalpha and LXRbeta. Genes Dev.
, vol.14
, pp. 2819-2830
-
-
Repa, J.J.1
Liang, G.2
Ou, J.3
Bashmakov, Y.4
Lobaccaro, J.M.5
Shimomura, I.6
Shan, B.7
Brown, M.S.8
Goldstein, J.L.9
Mangelsdorf, D.J.10
-
58
-
-
42149148782
-
IGF-1 induces SREBP-1 expression and lipogenesis in SEB-1 sebocytes via activation of the phosphoinositide 3-kinase/Akt pathway
-
Smith, T. M., K. Gilliland, G. A. Clawson, and D. Thiboutot. 2008. IGF-1 induces SREBP-1 expression and lipogenesis in SEB-1 sebocytes via activation of the phosphoinositide 3-kinase/Akt pathway. J. Invest. Dermatol. 128: 1286-1293.
-
(2008)
J. Invest. Dermatol.
, vol.128
, pp. 1286-1293
-
-
Smith, T.M.1
Gilliland, K.2
Clawson, G.A.3
Thiboutot, D.4
-
59
-
-
33745896223
-
Defi ciency of carbohydrate-activated transcription factor ChREBP prevents obesity and improves plasma glucose control in leptin-defi cient (ob/ob) mice
-
Iizuka, K., B. Miller, and K. Uyeda. 2006. Defi ciency of carbohydrate-activated transcription factor ChREBP prevents obesity and improves plasma glucose control in leptin-defi cient (ob/ob) mice. Am. J. Physiol. Endocrino l. Metab. 291: E358-E364.
-
(2006)
Am. J. Physiol. Endocrino L. Metab.
, vol.291
-
-
Iizuka, K.1
Miller, B.2
Uyeda, K.3
-
60
-
-
84893451810
-
ChREBP, a glucoseresponsive transcriptional factor, enhances glucose metabolism to support biosynthesis in human cytomegalovir us-infected cells
-
Yu, Y., T. G. Maguire, and J. C. Alwine. 2014. ChREBP, a glucoseresponsive transcriptional factor, enhances glucose metabolism to support biosynthesis in human cytomegalovir us-infected cells. Proc. Natl. Acad. Sci. USA. 111: 1951-1956.
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 1951-1956
-
-
Yu, Y.1
Maguire, T.G.2
Alwine, J.C.3
-
61
-
-
40549125618
-
ChREBP, but not LXRs, is required for the induction of glucose-regulated genes in mouse liver
-
Denechaud, P. D., P. Bossard, J. M. Lobaccaro, L. Millatt, B. Staels, J. Girard, and C. Postic. 2008. ChREBP, but not LXRs, is required for the induction of glucose-regulated genes in mouse liver. J. Clin. Invest. 118: 956-964.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 956-964
-
-
Denechaud, P.D.1
Bossard, P.2
Lobaccaro, J.M.3
Millatt, L.4
Staels, B.5
Girard, J.6
Postic, C.7
-
62
-
-
61849095626
-
Enhanced free cholesterol, SREBP-2 and StAR expression in human NASH
-
Caballero, F., A. Fernandez, A. M. De Lacy, J. C. Fernandez-Checa, J. Caballeria, and C. Garcia-Ruiz. 2009. Enhanced free cholesterol, SREBP-2 and StAR expression in human NASH. J. Hepatol. 50: 789-796.
-
(2009)
J. Hepatol.
, vol.50
, pp. 789-796
-
-
Caballero, F.1
Fernandez, A.2
De Lacy, A.M.3
Fernandez-Checa, J.C.4
Caballeria, J.5
Garcia-Ruiz, C.6
-
63
-
-
18244382304
-
Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
-
Donnelly, K. L., C. I. Smith, S. J. Schwarzenberg, J. Jessurun, M. D. Boldt, and E. J. Parks. 2005. Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J. Clin. Invest. 115: 1343-1351.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 1343-1351
-
-
Donnelly, K.L.1
Smith, C.I.2
Schwarzenberg, S.J.3
Jessurun, J.4
Boldt, M.D.5
Parks, E.J.6
-
64
-
-
22544480378
-
" New" hepatic fat activates PPARalpha to maintain glucose, lipid, and cholesterol homeostasis
-
Chakravarthy, M. V., Z. Pan, Y. Zhu, K. Tordjman, J. G. Schneider, T. Coleman, J. Turk, and C. F. Semenkovich. 2005. " New" hepatic fat activates PPARalpha to maintain glucose, lipid, and cholesterol homeostasis. Cell Metab. 1: 309-322.
-
(2005)
Cell Metab.
, vol.1
, pp. 309-322
-
-
Chakravarthy, M.V.1
Pan, Z.2
Zhu, Y.3
Tordjman, K.4
Schneider, J.G.5
Coleman, T.6
Turk, J.7
Semenkovich, C.F.8
-
65
-
-
84873295485
-
TSC22D4 is a molecular outpu t of hepatic wasting metabolism
-
Jones, A., K. Friedrich, M. Rohm, M. Schäfer, C. Algire, P. Kulozik, O. Seibert, K. Müller-Decker, T. Sijmonsma, D. Strzoda, et al. 2013. TSC22D4 is a molecular outpu t of hepatic wasting metabolism. EMBO Mol. Med. 5: 294-308.
-
(2013)
EMBO Mol. Med.
, vol.5
, pp. 294-308
-
-
Jones, A.1
Friedrich, K.2
Rohm, M.3
Schäfer, M.4
Algire, C.5
Kulozik, P.6
Seibert, O.7
Müller-Decker, K.8
Sijmonsma, T.9
Strzoda, D.10
-
66
-
-
33646812161
-
Fenofi brate, a peroxisome proliferator-activated receptor alpha agonist, reduces hepatic steatosis and lipid peroxidation in fatty liver Shionogi mice with hereditary fatty liver
-
Harano, Y., K. Yasui, T. Toyama, T. Nakajima, H. Mitsuyoshi, M. Mimani, T. Hirasawa, Y. Itoh, and T. Okanoue. 2006. Fenofi brate, a peroxisome proliferator-activated receptor alpha agonist, reduces hepatic steatosis and lipid peroxidation in fatty liver Shionogi mice with hereditary fatty liver. Liver Int. 26: 613-620.
-
(2006)
Liver Int.
, vol.26
, pp. 613-620
-
-
Harano, Y.1
Yasui, K.2
Toyama, T.3
Nakajima, T.4
Mitsuyoshi, H.5
Mimani, M.6
Hirasawa, T.7
Itoh, Y.8
Okanoue, T.9
-
67
-
-
0034806134
-
Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoAinduced inhibition of fatty acid oxidation and cytotoxicity
-
Thupari , J. N., M. L. Pinn, and F. P. Kuhajda. 2001. Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoAinduced inhibition of fatty acid oxidation and cytotoxicity. Biochem. Biophys. Res. Commun. 285: 217- 223.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.285
, pp. 217-223
-
-
Thupari, J.N.1
Pinn, M.L.2
Kuhajda, F.P.3
-
68
-
-
43249086785
-
Mammalian long-chain acyl-CoA synthetases
-
Soupene, E., and F. A. Kuypers. 2008. Mammalian long-chain acyl-CoA synthetases. Exp. Biol. Med. (Maywood). 233: 507-521.
-
(2008)
Exp. Biol. Med. (Maywood
, vol.233
, pp. 507-521
-
-
Soupene, E.1
Kuypers, F.A.2
-
69
-
-
0025237826
-
Acute hormonal control of acetyl-CoA carboxylase. The roles of insulin, glucagon, and epinephrine
-
Mabrouk, G. M., I. M. Helmy, K. G. Thampy, and S. J. Wakil. 1990. Acute hormonal control of acetyl-CoA carboxylase. The roles of insulin, glucagon, and epinephrine. J. Biol. Chem. 265: 6330-6338.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 6330-6338
-
-
Mabrouk, G.M.1
Helmy, I.M.2
Thampy, K.G.3
Wakil, S.J.4
-
70
-
-
0031043030
-
The mitochondrial carnitine palmitoyltransferase system. from concept to molecular analysis
-
McGarry, J. D., and N. F. Brown. 1997. The mitochondrial carnitine palmitoyltransferase system. From concept to molecular analysis. Eur. J. Biochem. 244: 1-14.
-
(1997)
Eur. J. Biochem.
, vol.244
, pp. 1-14
-
-
Mc Garry, J.D.1
Brown, N.F.2
-
71
-
-
54049150442
-
Molecular mechanisms and therapeutic targets in steatosis and steatohepatitis
-
Anderson, N., and J. Borlak. 2008. Molecular mechanisms and therapeutic targets in steatosis and steatohepatitis. Pharmacol. Rev. 60: 311-357.
-
(2008)
Pharmacol. Rev.
, vol.60
, pp. 311-357
-
-
Anderson, N.1
Borlak, J.2
-
73
-
-
21744460524
-
Transcrip t and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis
-
Lelliott, C. J., M. Lopez, R. K. Curtis, N. Parker, M. Laudes, G. Yeo, M. Jimenez-Linan, J. Grosse, A. K. Saha, D. Wiggins, et al. 2005. Transcrip t and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis. FASEB J. 19: 1108-1119.
-
(2005)
FASEB J.
, vol.19
, pp. 1108-1119
-
-
Lelliott, C.J.1
Lopez, M.2
Curtis, R.K.3
Parker, N.4
Laudes, M.5
Yeo, G.6
Jimenez-Linan, M.7
Grosse, J.8
Saha, A.K.9
Wiggins, D.10
|