-
1
-
-
0037198749
-
Chronic hepatitis B
-
Lok A.S. Chronic hepatitis B. N Engl J Med 346 (2002) 1682-1683
-
(2002)
N Engl J Med
, vol.346
, pp. 1682-1683
-
-
Lok, A.S.1
-
2
-
-
20444426467
-
Hepatic steatosis in chronic hepatitis B and C: predictors, distribution and effect on fibrosis
-
Gordon A., McLean C.A., Pedersen J.S., Bailey M.J., and Roberts S.K. Hepatic steatosis in chronic hepatitis B and C: predictors, distribution and effect on fibrosis. J Hepatol 43 (2005) 38-44
-
(2005)
J Hepatol
, vol.43
, pp. 38-44
-
-
Gordon, A.1
McLean, C.A.2
Pedersen, J.S.3
Bailey, M.J.4
Roberts, S.K.5
-
4
-
-
0037714524
-
Hepatic steatosis is a risk factor for hepatocellular carcinoma in patients with chronic hepatitis C virus infection
-
Ohata K., Hamasaki K., Toriyama K., Matsumoto K., Saeki A., Yanagi K., Abiru S., Nakagawa Y., Shigeno M., Miyazoe S., Ichikawa T., Ishikawa H., Nakao K., and Eguchi K. Hepatic steatosis is a risk factor for hepatocellular carcinoma in patients with chronic hepatitis C virus infection. Cancer 97 (2003) 3036-3043
-
(2003)
Cancer
, vol.97
, pp. 3036-3043
-
-
Ohata, K.1
Hamasaki, K.2
Toriyama, K.3
Matsumoto, K.4
Saeki, A.5
Yanagi, K.6
Abiru, S.7
Nakagawa, Y.8
Shigeno, M.9
Miyazoe, S.10
Ichikawa, T.11
Ishikawa, H.12
Nakao, K.13
Eguchi, K.14
-
5
-
-
23044439383
-
cDNA microarray analysis of HBV transgenic mouse liver identifies genes in lipid biosynthetic and growth control pathways affected by HBV
-
Hajjou M., Norel R., Carver R., Marion P., Cullen J., Rogler L.E., and Rogler C.E. cDNA microarray analysis of HBV transgenic mouse liver identifies genes in lipid biosynthetic and growth control pathways affected by HBV. J Med Virol 77 (2005) 57-65
-
(2005)
J Med Virol
, vol.77
, pp. 57-65
-
-
Hajjou, M.1
Norel, R.2
Carver, R.3
Marion, P.4
Cullen, J.5
Rogler, L.E.6
Rogler, C.E.7
-
6
-
-
3142582066
-
The hepatitis B virus X protein inhibits secretion of apolipoprotein B by enhancing the expression of N-acetylglucosaminyltransferase III
-
Kang S.K., Chung T.W., Lee J.Y., Lee Y.C., Morton R.E., and Kim C.H. The hepatitis B virus X protein inhibits secretion of apolipoprotein B by enhancing the expression of N-acetylglucosaminyltransferase III. J Biol Chem 279 (2004) 28106-28112
-
(2004)
J Biol Chem
, vol.279
, pp. 28106-28112
-
-
Kang, S.K.1
Chung, T.W.2
Lee, J.Y.3
Lee, Y.C.4
Morton, R.E.5
Kim, C.H.6
-
7
-
-
0027490174
-
SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene
-
Yokoyama C., Wang X., Briggs M.R., Admon A., Wu J., Hua X., Goldstein J.L., and Brown M.S. SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene. Cell 75 (1993) 187-197
-
(1993)
Cell
, vol.75
, pp. 187-197
-
-
Yokoyama, C.1
Wang, X.2
Briggs, M.R.3
Admon, A.4
Wu, J.5
Hua, X.6
Goldstein, J.L.7
Brown, M.S.8
-
8
-
-
0030941803
-
The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
-
Goldstein J.L., and Brown M.S. The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell 89 (1997) 331-340
-
(1997)
Cell
, vol.89
, pp. 331-340
-
-
Goldstein, J.L.1
Brown, M.S.2
-
9
-
-
0028225462
-
SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis
-
Wang X., Sato R., Brown M.S., Hua X., and Goldstein J.L. SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis. Cell 77 (1994) 53-62
-
(1994)
Cell
, vol.77
, pp. 53-62
-
-
Wang, X.1
Sato, R.2
Brown, M.S.3
Hua, X.4
Goldstein, J.L.5
-
10
-
-
0030907175
-
Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells
-
Shimano H., Horton J.D., Shimomura I., Hammer R.E., Brown M.S., and Goldstein J.L. Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells. J Clin Invest 99 (1997) 846-854
-
(1997)
J Clin Invest
, vol.99
, pp. 846-854
-
-
Shimano, H.1
Horton, J.D.2
Shimomura, I.3
Hammer, R.E.4
Brown, M.S.5
Goldstein, J.L.6
-
11
-
-
0028180070
-
mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer
-
Tontonoz P., Hu E., Graves R.A., Budavari A.I., and Spiegelman B.M. mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer. Genes Dev 8 (1994) 1224-1234
-
(1994)
Genes Dev
, vol.8
, pp. 1224-1234
-
-
Tontonoz, P.1
Hu, E.2
Graves, R.A.3
Budavari, A.I.4
Spiegelman, B.M.5
-
12
-
-
0028641559
-
Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor
-
Tontonoz P., Hu E., and Spiegelman B.M. Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor. Cell 79 (1994) 1147-1156
-
(1994)
Cell
, vol.79
, pp. 1147-1156
-
-
Tontonoz, P.1
Hu, E.2
Spiegelman, B.M.3
-
13
-
-
0141446024
-
Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass
-
Gavrilova O., Haluzik M., Matsusue K., Cutson J.J., Johnson L., Dietz K.R., Nicol C.J., Vinson C., Gonzalez F.J., and Reitman M.L. Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass. J Biol Chem 278 (2003) 34268-34276
-
(2003)
J Biol Chem
, vol.278
, pp. 34268-34276
-
-
Gavrilova, O.1
Haluzik, M.2
Matsusue, K.3
Cutson, J.J.4
Johnson, L.5
Dietz, K.R.6
Nicol, C.J.7
Vinson, C.8
Gonzalez, F.J.9
Reitman, M.L.10
-
14
-
-
0346003777
-
Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor gamma1 (PPARgamma1) overexpression
-
Yu S., Matsusue K., Kashireddy P., Cao W.Q., Yeldandi V., Yeldandi A.V., Rao M.S., Gonzalez F.J., and Reddy J.K. Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor gamma1 (PPARgamma1) overexpression. J Biol Chem 278 (2003) 498-505
-
(2003)
J Biol Chem
, vol.278
, pp. 498-505
-
-
Yu, S.1
Matsusue, K.2
Kashireddy, P.3
Cao, W.Q.4
Yeldandi, V.5
Yeldandi, A.V.6
Rao, M.S.7
Gonzalez, F.J.8
Reddy, J.K.9
-
15
-
-
19444383246
-
PPARgamma2 regulates lipogenesis and lipid accumulation in steatotic hepatocytes
-
Schadinger S.E., Bucher N.L., Schreiber B.M., and Farmer S.R. PPARgamma2 regulates lipogenesis and lipid accumulation in steatotic hepatocytes. Am J Physiol 288 (2005) E1195-E1205
-
(2005)
Am J Physiol
, vol.288
-
-
Schadinger, S.E.1
Bucher, N.L.2
Schreiber, B.M.3
Farmer, S.R.4
-
16
-
-
0032489437
-
Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor alpha (PPARalpha)
-
Aoyama T., Peters J.M., Iritani N., Nakajima T., Furihata K., Hashimoto T., and Gonzalez F.J. Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor alpha (PPARalpha). J Biol Chem 273 (1998) 5678-5684
-
(1998)
J Biol Chem
, vol.273
, pp. 5678-5684
-
-
Aoyama, T.1
Peters, J.M.2
Iritani, N.3
Nakajima, T.4
Furihata, K.5
Hashimoto, T.6
Gonzalez, F.J.7
-
17
-
-
0032699670
-
Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting
-
Kersten S., Seydoux J., Peters J.M., Gonzalez F.J., Desvergne B., and Wahli W. Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting. J Clin Invest 103 (1999) 1489-1498
-
(1999)
J Clin Invest
, vol.103
, pp. 1489-1498
-
-
Kersten, S.1
Seydoux, J.2
Peters, J.M.3
Gonzalez, F.J.4
Desvergne, B.5
Wahli, W.6
-
18
-
-
0033594980
-
A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders
-
Leone T.C., Weinheimer C.J., and Kelly D.P. A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders. Proc Natl Acad Sci U S A 96 (1999) 7473-7478
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 7473-7478
-
-
Leone, T.C.1
Weinheimer, C.J.2
Kelly, D.P.3
-
19
-
-
0033058294
-
Incidence of hepatocellular carcinoma in transgenic mice expressing the hepatitis B virus X-protein
-
Yu D.Y., Moon H.B., Son J.K., Jeong S., Yu S.L., Yoon H., Han Y.M., Lee C.S., Park J.S., Lee C.H., Hyun B.H., Murakami S., and Lee K.K. Incidence of hepatocellular carcinoma in transgenic mice expressing the hepatitis B virus X-protein. J Hepatol 31 (1999) 123-132
-
(1999)
J Hepatol
, vol.31
, pp. 123-132
-
-
Yu, D.Y.1
Moon, H.B.2
Son, J.K.3
Jeong, S.4
Yu, S.L.5
Yoon, H.6
Han, Y.M.7
Lee, C.S.8
Park, J.S.9
Lee, C.H.10
Hyun, B.H.11
Murakami, S.12
Lee, K.K.13
-
20
-
-
4444349833
-
Selective coactivator interactions in gene activation by SREBP-1a and -1c
-
Toth J.I., Datta S., Athanikar J.N., Freedman L.P., and Osborne T.F. Selective coactivator interactions in gene activation by SREBP-1a and -1c. Mol Cell Biol 24 (2004) 8288-8300
-
(2004)
Mol Cell Biol
, vol.24
, pp. 8288-8300
-
-
Toth, J.I.1
Datta, S.2
Athanikar, J.N.3
Freedman, L.P.4
Osborne, T.F.5
-
21
-
-
0028875426
-
Sterol regulation of fatty acid synthase promoter. Coordinate feedback regulation of two major lipid pathways
-
Bennett M.K., Lopez J.M., Sanchez H.B., and Osborne T.F. Sterol regulation of fatty acid synthase promoter. Coordinate feedback regulation of two major lipid pathways. J Biol Chem 270 (1995) 25578-25583
-
(1995)
J Biol Chem
, vol.270
, pp. 25578-25583
-
-
Bennett, M.K.1
Lopez, J.M.2
Sanchez, H.B.3
Osborne, T.F.4
-
22
-
-
0142182771
-
Hepatitis B virus X protein regulates transactivation activity and protein stability of the cancer-amplified transcription coactivator ASC-2
-
Kong H.J., Park M.J., Hong S., Yu H.J., Lee Y.C., Choi Y.H., and Cheong J. Hepatitis B virus X protein regulates transactivation activity and protein stability of the cancer-amplified transcription coactivator ASC-2. Hepatology 38 (2003) 1258-1266
-
(2003)
Hepatology
, vol.38
, pp. 1258-1266
-
-
Kong, H.J.1
Park, M.J.2
Hong, S.3
Yu, H.J.4
Lee, Y.C.5
Choi, Y.H.6
Cheong, J.7
-
23
-
-
0035958854
-
Functional interaction of bZIP proteins and the large subunit of replication factor C in liver and adipose cells
-
Hong S., Park S.J., Kong H.J., Shuman J.D., and Cheong J. Functional interaction of bZIP proteins and the large subunit of replication factor C in liver and adipose cells. J Biol Chem 276 (2001) 28098-28105
-
(2001)
J Biol Chem
, vol.276
, pp. 28098-28105
-
-
Hong, S.1
Park, S.J.2
Kong, H.J.3
Shuman, J.D.4
Cheong, J.5
-
24
-
-
0034816729
-
Regulation of activating transcription factor-2 in early stage of the adipocyte differentiation program
-
Lee M.Y., Kong H.J., and Cheong J. Regulation of activating transcription factor-2 in early stage of the adipocyte differentiation program. Biochem Biophys Res Commun 281 (2001) 1241-1247
-
(2001)
Biochem Biophys Res Commun
, vol.281
, pp. 1241-1247
-
-
Lee, M.Y.1
Kong, H.J.2
Cheong, J.3
-
25
-
-
0018618705
-
A morphologic classification of proliferative and neoplastic hepatic lesions in mice
-
Frith C.H., and Ward J.M. A morphologic classification of proliferative and neoplastic hepatic lesions in mice. J Environ Pathol Toxicol 3 (1979) 329-351
-
(1979)
J Environ Pathol Toxicol
, vol.3
, pp. 329-351
-
-
Frith, C.H.1
Ward, J.M.2
-
26
-
-
0034235363
-
Regulation of sterol regulatory-element binding protein 1 gene expression in liver: role of insulin and protein kinase B/cAkt
-
Fleischmann M., and Iynedjian P.B. Regulation of sterol regulatory-element binding protein 1 gene expression in liver: role of insulin and protein kinase B/cAkt. Biochem J 349 (2000) 13-17
-
(2000)
Biochem J
, vol.349
, pp. 13-17
-
-
Fleischmann, M.1
Iynedjian, P.B.2
-
27
-
-
10744228468
-
Hepatic Akt activation induces marked hypoglycemia, hepatomegaly, and hypertriglyceridemia with sterol regulatory element binding protein involvement
-
Ono H., Shimano H., Katagiri H., Yahagi N., Sakoda H., Onishi Y., Anai M., Ogihara T., Fujishiro M., Viana A.Y., Fukushima Y., Abe M., Shojima N., Kikuchi M., Yamada N., Oka Y., and Asano T. Hepatic Akt activation induces marked hypoglycemia, hepatomegaly, and hypertriglyceridemia with sterol regulatory element binding protein involvement. Diabetes 52 (2003) 2905-2913
-
(2003)
Diabetes
, vol.52
, pp. 2905-2913
-
-
Ono, H.1
Shimano, H.2
Katagiri, H.3
Yahagi, N.4
Sakoda, H.5
Onishi, Y.6
Anai, M.7
Ogihara, T.8
Fujishiro, M.9
Viana, A.Y.10
Fukushima, Y.11
Abe, M.12
Shojima, N.13
Kikuchi, M.14
Yamada, N.15
Oka, Y.16
Asano, T.17
-
28
-
-
0035907311
-
The hepatitis B virus-X protein activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade
-
Lee Y.I., Kang-Park S., Do S.I., and Lee Y.I. The hepatitis B virus-X protein activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade. J Biol Chem 276 (2001) 16969-16977
-
(2001)
J Biol Chem
, vol.276
, pp. 16969-16977
-
-
Lee, Y.I.1
Kang-Park, S.2
Do, S.I.3
Lee, Y.I.4
-
29
-
-
85047694402
-
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
-
Horie Y., Suzuki A., Kataoka E., Sasaki T., Hamada K., Sasaki J., Mizuno K., Hasegawa G., Kishimoto H., Iizuka M., Naito M., Enomoto K., Watanabe S., Mak T.W., and Nakano T. Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas. J Clin Invest 113 (2004) 1774-1783
-
(2004)
J Clin Invest
, vol.113
, pp. 1774-1783
-
-
Horie, Y.1
Suzuki, A.2
Kataoka, E.3
Sasaki, T.4
Hamada, K.5
Sasaki, J.6
Mizuno, K.7
Hasegawa, G.8
Kishimoto, H.9
Iizuka, M.10
Naito, M.11
Enomoto, K.12
Watanabe, S.13
Mak, T.W.14
Nakano, T.15
-
30
-
-
0036007024
-
C/EBPalpha induces adipogenesis through PPARgamma: a unified pathway
-
Rosen E.D., Hsu C.H., Wang X., Sakai S., Freeman M.W., Gonzalez F.J., and Spiegelman B.M. C/EBPalpha induces adipogenesis through PPARgamma: a unified pathway. Genes Dev 16 (2002) 22-26
-
(2002)
Genes Dev
, vol.16
, pp. 22-26
-
-
Rosen, E.D.1
Hsu, C.H.2
Wang, X.3
Sakai, S.4
Freeman, M.W.5
Gonzalez, F.J.6
Spiegelman, B.M.7
-
31
-
-
4043077961
-
Molecular mediators of hepatic steatosis and liver injury
-
Browning J.D., and Horton J.D. Molecular mediators of hepatic steatosis and liver injury. J Clin Invest 114 (2004) 147-152
-
(2004)
J Clin Invest
, vol.114
, pp. 147-152
-
-
Browning, J.D.1
Horton, J.D.2
-
32
-
-
0031800754
-
Liver biopsy is a useful predictor of response to interferon therapy in chronic hepatitis C
-
Kaserer K., Fiedler R., Steindl P., Muller C.H., Wrba F., and Ferenci P. Liver biopsy is a useful predictor of response to interferon therapy in chronic hepatitis C. Histopathology 32 (1998) 454-461
-
(1998)
Histopathology
, vol.32
, pp. 454-461
-
-
Kaserer, K.1
Fiedler, R.2
Steindl, P.3
Muller, C.H.4
Wrba, F.5
Ferenci, P.6
-
33
-
-
0034857085
-
Steatosis in chronic hepatitis C: can weight reduction improve therapeutic efficacy?
-
Giannini E., Ceppa P., and Testa R. Steatosis in chronic hepatitis C: can weight reduction improve therapeutic efficacy?. J Hepatol 35 (2001) 432-433
-
(2001)
J Hepatol
, vol.35
, pp. 432-433
-
-
Giannini, E.1
Ceppa, P.2
Testa, R.3
-
34
-
-
0034753082
-
Hepatitis B virus X protein: a multifunctional viral regulator
-
Murakami S. Hepatitis B virus X protein: a multifunctional viral regulator. J Gastroenterol 36 (2001) 651-660
-
(2001)
J Gastroenterol
, vol.36
, pp. 651-660
-
-
Murakami, S.1
-
35
-
-
0034773404
-
Role of AMP-activated protein kinase in mechanism of metformin action
-
Zhou G., Myers R., Li Y., Chen Y., Shen X., Fenyk-Melody J., Wu M., Ventre J., Doebber T., Fujii N., Musi N., Hirshman M.F., Goodyear L.J., and Moller D.E. Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest 108 (2001) 1167-1174
-
(2001)
J Clin Invest
, vol.108
, pp. 1167-1174
-
-
Zhou, G.1
Myers, R.2
Li, Y.3
Chen, Y.4
Shen, X.5
Fenyk-Melody, J.6
Wu, M.7
Ventre, J.8
Doebber, T.9
Fujii, N.10
Musi, N.11
Hirshman, M.F.12
Goodyear, L.J.13
Moller, D.E.14
-
36
-
-
30844448578
-
KGF induces lipogenic genes through a PI3K and JNK/SREBP-1 pathway in H292 cells
-
Chang Y., Wang J., Lu X., Thewke D.P., and Mason R.J. KGF induces lipogenic genes through a PI3K and JNK/SREBP-1 pathway in H292 cells. J Lipid Res 46 (2005) 2624-2635
-
(2005)
J Lipid Res
, vol.46
, pp. 2624-2635
-
-
Chang, Y.1
Wang, J.2
Lu, X.3
Thewke, D.P.4
Mason, R.J.5
-
37
-
-
0344972105
-
ADD1/SREBP-1c mediates insulin-induced gene expression linked to the MAP kinase pathway
-
Kotzka J., Muller-Wieland D., Koponen A., Njamen D., Kremer L., Roth G., Munck M., Knebel B., and Krone W. ADD1/SREBP-1c mediates insulin-induced gene expression linked to the MAP kinase pathway. Biochem Biophys Res Commun 249 (1998) 375-379
-
(1998)
Biochem Biophys Res Commun
, vol.249
, pp. 375-379
-
-
Kotzka, J.1
Muller-Wieland, D.2
Koponen, A.3
Njamen, D.4
Kremer, L.5
Roth, G.6
Munck, M.7
Knebel, B.8
Krone, W.9
-
38
-
-
2542546650
-
Hepatitis B virus X protein is essential for the activation of Wnt/beta-catenin signaling in hepatoma cells
-
Cha M.Y., Kim C.M., Park Y.M., and Ryu W.S. Hepatitis B virus X protein is essential for the activation of Wnt/beta-catenin signaling in hepatoma cells. Hepatology 39 (2004) 1683-1693
-
(2004)
Hepatology
, vol.39
, pp. 1683-1693
-
-
Cha, M.Y.1
Kim, C.M.2
Park, Y.M.3
Ryu, W.S.4
-
39
-
-
0029587224
-
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
-
Cross D.A., Alessi D.R., Cohen P., Andjelkovich M., and Hemmings B.A. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378 (1995) 785-789
-
(1995)
Nature
, vol.378
, pp. 785-789
-
-
Cross, D.A.1
Alessi, D.R.2
Cohen, P.3
Andjelkovich, M.4
Hemmings, B.A.5
-
40
-
-
10644281006
-
Regulatory role of glycogen synthase kinase 3 for transcriptional activity of ADD1/SREBP1c
-
Kim K.H., Song M.J., Yoo E.J., Choe S.S., Park S.D., and Kim J.B. Regulatory role of glycogen synthase kinase 3 for transcriptional activity of ADD1/SREBP1c. J Biol Chem 279 (2004) 51999-52006
-
(2004)
J Biol Chem
, vol.279
, pp. 51999-52006
-
-
Kim, K.H.1
Song, M.J.2
Yoo, E.J.3
Choe, S.S.4
Park, S.D.5
Kim, J.B.6
-
41
-
-
0034019329
-
Dietary choline restriction causes complex I dysfunction and increased H(2)O(2) generation in liver mitochondria
-
Hensley K., Kotake Y., Sang H., Pye Q.N., Wallis G.L., Kolker L.M., Tabatabaie T., Stewart C.A., Konishi Y., Nakae D., and Floyd R.A. Dietary choline restriction causes complex I dysfunction and increased H(2)O(2) generation in liver mitochondria. Carcinogenesis 21 (2000) 983-989
-
(2000)
Carcinogenesis
, vol.21
, pp. 983-989
-
-
Hensley, K.1
Kotake, Y.2
Sang, H.3
Pye, Q.N.4
Wallis, G.L.5
Kolker, L.M.6
Tabatabaie, T.7
Stewart, C.A.8
Konishi, Y.9
Nakae, D.10
Floyd, R.A.11
-
42
-
-
0036652185
-
Oxidative stress in the pathogenesis of nonalcoholic fatty liver disease, in rats fed with a choline-deficient diet
-
Oliveira C.P., da Costa Gayotto L.C., Tatai C., Della Bina B.I., Janiszew-ski M., Lima E.S., Abdalla D.S., Lopasso F.P., Laurindo F.R., and Laudanna A.A. Oxidative stress in the pathogenesis of nonalcoholic fatty liver disease, in rats fed with a choline-deficient diet. J Cell Mol Med 6 (2002) 399-406
-
(2002)
J Cell Mol Med
, vol.6
, pp. 399-406
-
-
Oliveira, C.P.1
da Costa Gayotto, L.C.2
Tatai, C.3
Della Bina, B.I.4
Janiszew-ski, M.5
Lima, E.S.6
Abdalla, D.S.7
Lopasso, F.P.8
Laurindo, F.R.9
Laudanna, A.A.10
-
43
-
-
0742306111
-
CYP2E1: from ASH to NASH
-
Lieber C.S. CYP2E1: from ASH to NASH. Hepatol Res 28 (2004) 1-11
-
(2004)
Hepatol Res
, vol.28
, pp. 1-11
-
-
Lieber, C.S.1
-
44
-
-
0035991444
-
In situ detection of lipid peroxidation and oxidative DNA damage in non-alcoholic fatty liver diseases
-
Seki S., Kitada T., Yamada T., Sakaguchi H., Nakatani K., and Wakasa K. In situ detection of lipid peroxidation and oxidative DNA damage in non-alcoholic fatty liver diseases. J Hepatol 37 (2002) 56-62
-
(2002)
J Hepatol
, vol.37
, pp. 56-62
-
-
Seki, S.1
Kitada, T.2
Yamada, T.3
Sakaguchi, H.4
Nakatani, K.5
Wakasa, K.6
-
45
-
-
0034659814
-
Mitochondrial adaptations to obesity-related oxidant stress
-
Yang S., Zhu H., Li Y., Lin H., Gabrielson K., Trush M.A., and Diehl A.M. Mitochondrial adaptations to obesity-related oxidant stress. Arch Biochem Biophys 378 (2000) 259-268
-
(2000)
Arch Biochem Biophys
, vol.378
, pp. 259-268
-
-
Yang, S.1
Zhu, H.2
Li, Y.3
Lin, H.4
Gabrielson, K.5
Trush, M.A.6
Diehl, A.M.7
-
46
-
-
0034774463
-
Mitochondrially associated hepatitis B virus X protein constitutively activates transcription factors STAT-3 and NF-kappa B via oxidative stress
-
Waris G., Huh K.W., and Siddiqui A.R. Mitochondrially associated hepatitis B virus X protein constitutively activates transcription factors STAT-3 and NF-kappa B via oxidative stress. Mol Cell Biol 21 (2001) 7721-7730
-
(2001)
Mol Cell Biol
, vol.21
, pp. 7721-7730
-
-
Waris, G.1
Huh, K.W.2
Siddiqui, A.R.3
-
47
-
-
0038158319
-
Hepatitis B virus X protein induces cell death by causing loss of mitochondrial membrane potential
-
Shirakata Y., and Koike K. Hepatitis B virus X protein induces cell death by causing loss of mitochondrial membrane potential. J Biol Chem 278 (2003) 22071-22078
-
(2003)
J Biol Chem
, vol.278
, pp. 22071-22078
-
-
Shirakata, Y.1
Koike, K.2
-
48
-
-
2442452762
-
Human hepatitis B virus-X protein alters mitochondrial function and physiology in human liver cells
-
Lee Y.I., Hwang J.M., Im J.H., Lee Y.I., Kim N.S., Kim D.G., Yu D.Y., Moon H.B., and Park S.K. Human hepatitis B virus-X protein alters mitochondrial function and physiology in human liver cells. J Biol Chem 279 (2004) 15460-15471
-
(2004)
J Biol Chem
, vol.279
, pp. 15460-15471
-
-
Lee, Y.I.1
Hwang, J.M.2
Im, J.H.3
Lee, Y.I.4
Kim, N.S.5
Kim, D.G.6
Yu, D.Y.7
Moon, H.B.8
Park, S.K.9
-
49
-
-
0036708287
-
Hepatitis B virus X protein induced expression of interleukin 18 (IL-18): a potential mechanism for liver injury caused by hepatitis B virus (HBV) infection
-
Lee M.O., Choi Y.H., Shin E.C., Kang H.J., Kim Y.M., Jeong S.Y., Seong J.K., Yu D.Y., Cho H., Park J.H., and Kim S.J. Hepatitis B virus X protein induced expression of interleukin 18 (IL-18): a potential mechanism for liver injury caused by hepatitis B virus (HBV) infection. J Hepatol 37 (2002) 380-386
-
(2002)
J Hepatol
, vol.37
, pp. 380-386
-
-
Lee, M.O.1
Choi, Y.H.2
Shin, E.C.3
Kang, H.J.4
Kim, Y.M.5
Jeong, S.Y.6
Seong, J.K.7
Yu, D.Y.8
Cho, H.9
Park, J.H.10
Kim, S.J.11
-
50
-
-
14944374003
-
Impaired expression of the peroxisome proliferator-activated receptor alpha during hepatitis C virus infection
-
Dharancy S., Malapel M., Perlemuter G., Roskams T., Cheng Y., Dubuquoy L., Podevin P., Conti F., Canva V., Philippe D., Gambiez L., Mathurin P., Paris J.C., Schoonjans K., Calmus Y., Pol S., Auwerx J., and Desreumaux P. Impaired expression of the peroxisome proliferator-activated receptor alpha during hepatitis C virus infection. Gastroenterology 128 (2005) 334-342
-
(2005)
Gastroenterology
, vol.128
, pp. 334-342
-
-
Dharancy, S.1
Malapel, M.2
Perlemuter, G.3
Roskams, T.4
Cheng, Y.5
Dubuquoy, L.6
Podevin, P.7
Conti, F.8
Canva, V.9
Philippe, D.10
Gambiez, L.11
Mathurin, P.12
Paris, J.C.13
Schoonjans, K.14
Calmus, Y.15
Pol, S.16
Auwerx, J.17
Desreumaux, P.18
-
51
-
-
0028970387
-
Retinoid X receptor alpha transactivates the hepatitis B virus enhancer 1 element by forming a heterodimeric complex with the peroxisome proliferator-activated receptor
-
Huan B., Kosovsky M.J., and Siddiqui A. Retinoid X receptor alpha transactivates the hepatitis B virus enhancer 1 element by forming a heterodimeric complex with the peroxisome proliferator-activated receptor. J Virol 69 (1995) 547-551
-
(1995)
J Virol
, vol.69
, pp. 547-551
-
-
Huan, B.1
Kosovsky, M.J.2
Siddiqui, A.3
-
52
-
-
0032710927
-
In vivo regulation of hepatitis B virus replication by peroxisome proliferators
-
Guidotti L.G., Eggers C.M., Raney A.K., Chi S.Y., Peters J.M., Gonzalez F.J., and McLachlan A. In vivo regulation of hepatitis B virus replication by peroxisome proliferators. J Virol 73 (1999) 10377-10386
-
(1999)
J Virol
, vol.73
, pp. 10377-10386
-
-
Guidotti, L.G.1
Eggers, C.M.2
Raney, A.K.3
Chi, S.Y.4
Peters, J.M.5
Gonzalez, F.J.6
McLachlan, A.7
-
53
-
-
0035169616
-
Critical roles of nuclear receptor response elements in replication of hepatitis B virus
-
Yu X., and Mertz J.E. Critical roles of nuclear receptor response elements in replication of hepatitis B virus. J Virol 75 (2001) 11354-11364
-
(2001)
J Virol
, vol.75
, pp. 11354-11364
-
-
Yu, X.1
Mertz, J.E.2
-
54
-
-
0345212927
-
Hepatitis B virus (HBV) particles are produced in a cell culture system by transient expression of transfected HBV DNA
-
Yaginuma K., Shirakata Y., Kobayashi M., and Koike K. Hepatitis B virus (HBV) particles are produced in a cell culture system by transient expression of transfected HBV DNA. Proc Natl Acad Sci U S A 84 (1987) 2678-2682
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, pp. 2678-2682
-
-
Yaginuma, K.1
Shirakata, Y.2
Kobayashi, M.3
Koike, K.4
-
55
-
-
0035861455
-
Calcium signaling by HBx protein in hepatitis B virus DNA replication
-
Bouchard M.J., Wang L.H., and Schneider R.J. Calcium signaling by HBx protein in hepatitis B virus DNA replication. Science 294 (2001) 2376-2378
-
(2001)
Science
, vol.294
, pp. 2376-2378
-
-
Bouchard, M.J.1
Wang, L.H.2
Schneider, R.J.3
-
56
-
-
16544364359
-
Inhibition of cellular proteasome activities enhances hepadnavirus replication in an HBX-dependent manner
-
Zhang Z., Protzer U., Hu Z., Jacob J., and Liang T.J. Inhibition of cellular proteasome activities enhances hepadnavirus replication in an HBX-dependent manner. J Virol 78 (2004) 4566-4572
-
(2004)
J Virol
, vol.78
, pp. 4566-4572
-
-
Zhang, Z.1
Protzer, U.2
Hu, Z.3
Jacob, J.4
Liang, T.J.5
-
57
-
-
0036171745
-
Enhancement of hepatitis B virus replication by its X protein in transgenic mice
-
Xu Z., Yen T.S., Wu L., Madden C.R., Tan W., Slagle B.L., and Ou J.H. Enhancement of hepatitis B virus replication by its X protein in transgenic mice. J Virol 76 (2002) 2579-2584
-
(2002)
J Virol
, vol.76
, pp. 2579-2584
-
-
Xu, Z.1
Yen, T.S.2
Wu, L.3
Madden, C.R.4
Tan, W.5
Slagle, B.L.6
Ou, J.H.7
-
58
-
-
34247595862
-
Enhancement of hepatitis B virus replication by the regulatory X protein in vitro and in vivo
-
[Epub ahead of print]
-
Keasler V.V., Hodgson A.J., Madden C.R., and Slagle B.L. Enhancement of hepatitis B virus replication by the regulatory X protein in vitro and in vivo. J Virol (2006) [Epub ahead of print]
-
(2006)
J Virol
-
-
Keasler, V.V.1
Hodgson, A.J.2
Madden, C.R.3
Slagle, B.L.4
-
59
-
-
33644882808
-
Peroxisome proliferator-activated receptor-alpha and -gamma mRNA levels are reduced in chronic hepatitis C with steatosis and genotype 3 infection
-
de Gottardi A., Pazienza V., Pugnale P., Bruttin F., Rubbia-Brandt L., Juge-Aubry C.E., Meier C.A., Hadengue A., and Negro F. Peroxisome proliferator-activated receptor-alpha and -gamma mRNA levels are reduced in chronic hepatitis C with steatosis and genotype 3 infection. Aliment Pharmacol Ther 23 (2006) 107-114
-
(2006)
Aliment Pharmacol Ther
, vol.23
, pp. 107-114
-
-
de Gottardi, A.1
Pazienza, V.2
Pugnale, P.3
Bruttin, F.4
Rubbia-Brandt, L.5
Juge-Aubry, C.E.6
Meier, C.A.7
Hadengue, A.8
Negro, F.9
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