Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoA-induced inhibition of fatty acid oxidation and cytotoxicity

Biochemical and Biophysical Research Communications

Volumn 285, Issue 2, 2001, Pages 217-223

  Thupari, Jagan N ^a   Pinn, Michael L ^a   Kuhajda, Francis P ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Acetyl CoA carboxylase; Cancer; Carnitine Palmitoyl transferase 1; Cerulenin; Etomoxir; Fatty acid synthase; Malonyl CoA

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; CARNITINE PALMITOYLTRANSFERASE; CERULENIN; ENZYME INHIBITOR; ETOMOXIR; FATTY ACID SYNTHASE; MALONYL COENZYME A;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ASSAY; ENZYME INHIBITION; FATTY ACID OXIDATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

EID: 0034806134     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.5146     Document Type: Article

References (24)