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Volumn 2013, Issue , 2013, Pages

Inhibition of LXR α /SREBP-1c-mediated hepatic steatosis by Jiang-Zhi Granule

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CHINESE DRUG; CHOLESTEROL; JIANG ZHI GRANULE; LIVER X RECEPTOR ALPHA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 84878687762     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2013/584634     Document Type: Article
Times cited : (15)

References (41)
  • 1
    • 2342459634 scopus 로고    scopus 로고
    • Non-alcoholic steatohepatitis in the Asia-Pacific region: Future shock?
    • DOI 10.1111/j.1440-1746.2003.03252.x
    • Chitturi S., Farrell G. C., George J., Non-alcoholic steatohepatitis in the Asia-Pacific region: future shock? Journal of Gastroenterology and Hepatology 2004 19 4 368 374 2-s2.0-2342459634 10.1111/j.1440-1746.2003.03252.x (Pubitemid 38570185)
    • (2004) Journal of Gastroenterology and Hepatology , vol.19 , Issue.4 , pp. 368-374
    • Chitturi, S.1    Farrell, G.C.2    George, J.3
  • 2
    • 66749106254 scopus 로고    scopus 로고
    • Epidemiology and natural history of non-alcoholic fatty liver disease (NAFLD)
    • supplement 1 2-s2.0-66749106254
    • Bellentani S., Marino M., Epidemiology and natural history of non-alcoholic fatty liver disease (NAFLD). Annals of Hepatology 2009 8 supplement 1 S4 S8 2-s2.0-66749106254
    • (2009) Annals of Hepatology , vol.8
    • Bellentani, S.1    Marino, M.2
  • 3
    • 79955538697 scopus 로고    scopus 로고
    • Prevalence and etiology of abnormal liver tests in an adult population in Jilin, China
    • Zhang H., He S. M., Sun J., Prevalence and etiology of abnormal liver tests in an adult population in Jilin, China. International Journal of Medical Sciences 2011 8 3 254 262
    • (2011) International Journal of Medical Sciences , vol.8 , Issue.3 , pp. 254-262
    • Zhang, H.1    He, S.M.2    Sun, J.3
  • 4
    • 79952680445 scopus 로고    scopus 로고
    • Relationship between nonalcoholic fatty liver disease and metabolic syndrome
    • Chen S. H., He F., Zhou H. L., Wu H. R., Xia C., Li Y. M., Relationship between nonalcoholic fatty liver disease and metabolic syndrome. Journal of Digestive Diseases 2011 12 2 25 130
    • (2011) Journal of Digestive Diseases , vol.12 , Issue.2 , pp. 25-130
    • Chen, S.H.1    He, F.2    Zhou, H.L.3    Wu, H.R.4    Xia, C.5    Li, Y.M.6
  • 5
    • 0028875908 scopus 로고
    • The natural history of nonalcoholic fatty liver: A follow-up study
    • 2-s2.0-0028875908
    • Teli M. R., James O. F. W., Burt A. D., Bennett M. K., Day C. P., The natural history of nonalcoholic fatty liver: a follow-up study. Hepatology 1995 22 6 1714 1719 2-s2.0-0028875908
    • (1995) Hepatology , vol.22 , Issue.6 , pp. 1714-1719
    • Teli, M.R.1    James, O.F.W.2    Burt, A.D.3    Bennett, M.K.4    Day, C.P.5
  • 6
    • 0037129380 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease
    • Angulo P., Nonalcoholic fatty liver disease. The New England Journal of Medicine 2002 346 16 1221 1231
    • (2002) The New England Journal of Medicine , vol.346 , Issue.16 , pp. 1221-1231
    • Angulo, P.1
  • 7
    • 84878723686 scopus 로고    scopus 로고
    • Systematic review of treating nonalcoholic fatty liver with taking TCM orally: A clinical randomized controlled trial
    • Wei H. F., Ji G., Systematic review of treating nonalcoholic fatty liver with taking TCM orally: a clinical randomized controlled trial. China Journal of Traditional Chinese Medicine and Pharmacy 2012 27 5 1309 1314
    • (2012) China Journal of Traditional Chinese Medicine and Pharmacy , vol.27 , Issue.5 , pp. 1309-1314
    • Wei, H.F.1    Ji, G.2
  • 8
    • 73849139340 scopus 로고    scopus 로고
    • Distribution pattern of traditional Chinese medicine syndromes in 793 patients with fatty liver disease
    • 2-s2.0-73849139340 10.3736/jcim20090503
    • Wei H. F., Liu T., Xing L. J., Zheng P. Y., Ji G., Distribution pattern of traditional Chinese medicine syndromes in 793 patients with fatty liver disease. Journal of Chinese Integrative Medicine 2009 7 5 411 417 2-s2.0-73849139340 10.3736/jcim20090503
    • (2009) Journal of Chinese Integrative Medicine , vol.7 , Issue.5 , pp. 411-417
    • Wei, H.F.1    Liu, T.2    Xing, L.J.3    Zheng, P.Y.4    Ji, G.5
  • 9
    • 78650906278 scopus 로고    scopus 로고
    • Simultaneous determination of six components in the 'Jiang-Zhi' Granule by UPLC-MS analysis
    • Lu Y. L., Wang M., Zhang L., Simultaneous determination of six components in the 'Jiang-Zhi' Granule by UPLC-MS analysis. Chinese Journal of Natural Medicines 2010 8 6 449 455
    • (2010) Chinese Journal of Natural Medicines , vol.8 , Issue.6 , pp. 449-455
    • Lu, Y.L.1    Wang, M.2    Zhang, L.3
  • 10
    • 84863154904 scopus 로고    scopus 로고
    • Effect of Chinese medicine Jiangzhi granula on hepaticlipid of nonalcoholic fatty liver disease rats
    • Ma Z. S., Liu T., Zheng P. Y., Effect of Chinese medicine Jiangzhi granula on hepaticlipid of nonalcoholic fatty liver disease rats. Chinese Archives of Traditional Chinese Medicine 2007 25 4 942 944
    • (2007) Chinese Archives of Traditional Chinese Medicine , vol.25 , Issue.4 , pp. 942-944
    • Ma, Z.S.1    Liu, T.2    Zheng, P.Y.3
  • 11
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipides from animal tissues
    • 2-s2.0-70449158340
    • Folch J., Lees M., Slane Stanley G. H., A simple method for the isolation and purification of total lipides from animal tissues. The Journal of Biological Chemistry 1957 226 1 497 509 2-s2.0-70449158340
    • (1957) The Journal of Biological Chemistry , vol.226 , Issue.1 , pp. 497-509
    • Folch, J.1    Lees, M.2    Slane Stanley, G.H.3
  • 12
    • 56149098763 scopus 로고    scopus 로고
    • Alpha-lipoic acid decreases hepatic lipogenesis through adenosine monophosphate-activated protein kinase (AMPK)-dependent and AMPK-independent pathways
    • 2-s2.0-56149098763 10.1002/hep.22496
    • Park K. G., Min A. K., Koh E. H., Kim H. S., Kim M. O., Park H. S., Kim Y. D., Yoo T. S., Jang B. K., Hwang J. S., Kim J. B., Choi H. S., Park J. Y., Lee I. K., Lee K. U., Alpha-lipoic acid decreases hepatic lipogenesis through adenosine monophosphate-activated protein kinase (AMPK)-dependent and AMPK-independent pathways. Hepatology 2008 48 5 1477 1486 2-s2.0-56149098763 10.1002/hep.22496
    • (2008) Hepatology , vol.48 , Issue.5 , pp. 1477-1486
    • Park, K.G.1    Min, A.K.2    Koh, E.H.3    Kim, H.S.4    Kim, M.O.5    Park, H.S.6    Kim, Y.D.7    Yoo, T.S.8    Jang, B.K.9    Hwang, J.S.10    Kim, J.B.11    Choi, H.S.12    Park, J.Y.13    Lee, I.K.14    Lee, K.U.15
  • 13
    • 84865865516 scopus 로고    scopus 로고
    • Alpha-lipoic acid induces adipose triglyceride lipase expression and decreases intracellular lipid accumulation in HepG2 cells
    • Kuo Y. T., Lin T. H., Chen W. L., Lee H. M., Alpha-lipoic acid induces adipose triglyceride lipase expression and decreases intracellular lipid accumulation in HepG2 cells. European Journal of Pharmacology 2012 692 1-3 10 18
    • (2012) European Journal of Pharmacology , vol.692 , Issue.1-3 , pp. 10-18
    • Kuo, Y.T.1    Lin, T.H.2    Chen, W.L.3    Lee, H.M.4
  • 14
    • 84865539649 scopus 로고    scopus 로고
    • Inhibition of the activation of hepatic stellate cells by arundic acid via the induction of cytoglobin
    • Cui W., Wang M., Maegawa H., Inhibition of the activation of hepatic stellate cells by arundic acid via the induction of cytoglobin. Biochemical and Biophysical Research Communications 2012 425 3 642 648
    • (2012) Biochemical and Biophysical Research Communications , vol.425 , Issue.3 , pp. 642-648
    • Cui, W.1    Wang, M.2    Maegawa, H.3
  • 15
    • 77950355485 scopus 로고    scopus 로고
    • Characterization of high-fat, diet-induced, non-alcoholic steatohepatitis with fibrosis in rats
    • 2-s2.0-77950355485 10.1007/s10620-009-0815-3
    • Xu Z. J., Fan J. G., Ding X. D., Qiao L., Wang G. L., Characterization of high-fat, diet-induced, non-alcoholic steatohepatitis with fibrosis in rats. Digestive Diseases and Sciences 2010 55 4 931 940 2-s2.0-77950355485 10.1007/s10620-009-0815-3
    • (2010) Digestive Diseases and Sciences , vol.55 , Issue.4 , pp. 931-940
    • Xu, Z.J.1    Fan, J.G.2    Ding, X.D.3    Qiao, L.4    Wang, G.L.5
  • 17
    • 80052211344 scopus 로고    scopus 로고
    • The role of hepatic liver X receptor alpha- and sterol regulatory element binding protein-1c-mediated lipid disorder in the pathogenesis of non-alcoholic steatohepatitis in rats
    • Ai Z. L., Zhu C. H., Min M., The role of hepatic liver X receptor alpha- and sterol regulatory element binding protein-1c-mediated lipid disorder in the pathogenesis of non-alcoholic steatohepatitis in rats. Journal of International Medical Research 2011 39 4 1219 1229
    • (2011) Journal of International Medical Research , vol.39 , Issue.4 , pp. 1219-1229
    • Ai, Z.L.1    Zhu, C.H.2    Min, M.3
  • 18
    • 80054801450 scopus 로고    scopus 로고
    • Melatonin alleviates lipopolysaccharide-induced hepatic SREBP-1c activation and lipid accumulation in mice
    • Chen X., Zhang C., Zhao M., Melatonin alleviates lipopolysaccharide- induced hepatic SREBP-1c activation and lipid accumulation in mice. Journal of Pineal Research 2011 51 4 416 425
    • (2011) Journal of Pineal Research , vol.51 , Issue.4 , pp. 416-425
    • Chen, X.1    Zhang, C.2    Zhao, M.3
  • 19
    • 0037196119 scopus 로고    scopus 로고
    • An LC-MS method for analyzing total resveratrol in grape juice, cranberry juice, and in wine
    • DOI 10.1021/jf010812u
    • Wang Y., Catana F., Yang Y., Roderick R., Van Breemen R. B., An LC-MS method for analyzing total resveratrol in grape juice, cranberry juice, and in wine. Journal of Agricultural and Food Chemistry 2002 50 3 431 435 2-s2.0-0037196119 10.1021/jf010812u (Pubitemid 34106659)
    • (2002) Journal of Agricultural and Food Chemistry , vol.50 , Issue.3 , pp. 431-435
    • Wang, Y.1    Catana, F.2    Yang, Y.3    Roderick, R.4    Van Breemen, R.B.5
  • 20
    • 77956024825 scopus 로고    scopus 로고
    • Antiobesity and hypolipidemic effects of lotus leaf hot water extract with taurine supplementation in rats fed a high fat diet
    • 2-s2.0-77956024825 10.1186/1423-0127-17-S1-S42
    • Du H., You J. S., Zhao X., Park J. Y., Kim S. H., Chang K. J., Antiobesity and hypolipidemic effects of lotus leaf hot water extract with taurine supplementation in rats fed a high fat diet. Journal of Biomedical Science 2010 17 1, article S42 2-s2.0-77956024825 10.1186/1423-0127-17-S1-S42
    • (2010) Journal of Biomedical Science , vol.17 , Issue.ARTICLE S42
    • Du, H.1    You, J.S.2    Zhao, X.3    Park, J.Y.4    Kim, S.H.5    Chang, K.J.6
  • 21
    • 84862801973 scopus 로고    scopus 로고
    • Emerging approaches of traditional Chinese medicine formulas for the treatment of hyperlipidemia
    • Xie W., Zhao Y., Du L., Emerging approaches of traditional Chinese medicine formulas for the treatment of hyperlipidemia. Journal of Ethnopharmacology 2012 140 2 345 367
    • (2012) Journal of Ethnopharmacology , vol.140 , Issue.2 , pp. 345-367
    • Xie, W.1    Zhao, Y.2    Du, L.3
  • 22
    • 84878689764 scopus 로고    scopus 로고
    • Clinical study of "jiang zhi Granule" and behavioral intervention for nonalcoholic fatty liver disease of phlegm and blood-stasis syndrome
    • Wang M., Liu T., Wei H. F., Clinical study of "Jiang zhi Granule" and behavioral intervention for nonalcoholic fatty liver disease of phlegm and blood-stasis syndrome. Shanghai Zhong Yi Yao Za Zhi 2010 44 4 11 13
    • (2010) Shanghai Zhong Yi Yao Za Zhi , vol.44 , Issue.4 , pp. 11-13
    • Wang, M.1    Liu, T.2    Wei, H.F.3
  • 23
    • 37549061921 scopus 로고    scopus 로고
    • Guidelines for diagnosis and treatment of nonalcoholic fatty liver diseases
    • Liver And Alcoholic Liver Disease Study Group Of The Chinese Liver Disease Association F.
    • Fatty Liver and Alcoholic Liver Disease Study Group of the Chinese Liver Disease Association, Guidelines for diagnosis and treatment of nonalcoholic fatty liver diseases. Chinese Journal of Hepatology 2006 14 3 161 163
    • (2006) Chinese Journal of Hepatology , vol.14 , Issue.3 , pp. 161-163
  • 24
    • 77955500907 scopus 로고    scopus 로고
    • Dietary fat intake promotes the development of hepatic steatosis independently from excess caloric consumption in a murine model
    • 2-s2.0-77955500907 10.1016/j.metabol.2009.11.006
    • de Meijer V. E., Le H. D., Meisel J. A., Sharif M. R. A., Pan A., Nosé V., Puder M., Dietary fat intake promotes the development of hepatic steatosis independently from excess caloric consumption in a murine model. Metabolism 2010 59 8 1092 1105 2-s2.0-77955500907 10.1016/j.metabol.2009.11.006
    • (2010) Metabolism , vol.59 , Issue.8 , pp. 1092-1105
    • De Meijer, V.E.1    Le, H.D.2    Meisel, J.A.3    Sharif, M.R.A.4    Pan, A.5    Nosé, V.6    Puder, M.7
  • 25
    • 19944430411 scopus 로고    scopus 로고
    • Hyperlipidemic effects of dietary saturated fats mediated through PGC-1β coactivation of SREBP
    • DOI 10.1016/j.cell.2004.11.043, PII S009286740401147X
    • Lin J., Yang R., Tarr P. T., Wu P. H., Handschin C., Li S., Yang W., Pei L., Uldry M., Tontonoz P., Newgard C. B., Spiegelman B. M., Hyperlipidemic effects of dietary saturated fats mediated through PGC-1 β coactivation of SREBP. Cell 2005 120 2 261 273 2-s2.0-19944430411 10.1016/j.cell.2004.11.043 (Pubitemid 40174768)
    • (2005) Cell , vol.120 , Issue.2 , pp. 261-273
    • Lin, J.1    Yang, R.2    Tarr, P.T.3    Wu, P.-H.4    Handschin, C.5    Li, S.6    Yang, W.7    Pei, L.8    Uldry, M.9    Tontonoz, P.10    Newgard, C.B.11    Spiegelman, B.M.12
  • 26
    • 43249127067 scopus 로고    scopus 로고
    • Role of stearoyl-coenzyme A desaturase in regulating lipid metabolism
    • DOI 10.1097/MOL.0b013e3282f9b54d, PII 0004143320080600000006
    • Flowers M. T., Ntambi J. M., Role of stearoyl-coenzyme A desaturase in regulating lipid metabolism. Current Opinion in Lipidology 2008 19 3 248 256 2-s2.0-43249127067 10.1097/MOL.0b013e3282f9b54d (Pubitemid 351653562)
    • (2008) Current Opinion in Lipidology , vol.19 , Issue.3 , pp. 248-256
    • Flowers, M.T.1    Ntambi, J.M.2
  • 27
    • 70449370069 scopus 로고    scopus 로고
    • Long-term baicalin administration ameliorates metabolic disorders and hepatic steatosis in rats given a high-fat diet
    • 2-s2.0-70449370069 10.1038/aps.2009.150
    • Guo H. X., Liu D. H., Ma Y., Liu J. F., Wang Y., Du Z. Y., Wang X., Shen J. K., Peng H. L., Long-term baicalin administration ameliorates metabolic disorders and hepatic steatosis in rats given a high-fat diet. Acta Pharmacologica Sinica 2009 30 11 1505 1512 2-s2.0-70449370069 10.1038/aps.2009.150
    • (2009) Acta Pharmacologica Sinica , vol.30 , Issue.11 , pp. 1505-1512
    • Guo, H.X.1    Liu, D.H.2    Ma, Y.3    Liu, J.F.4    Wang, Y.5    Du, Z.Y.6    Wang, X.7    Shen, J.K.8    Peng, H.L.9
  • 28
    • 53349153430 scopus 로고    scopus 로고
    • Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease
    • 2-s2.0-53349153430 10.1111/j.1872-034X.2008.00382.x
    • Higuchi N., Kato M., Shundo Y., Tajiri H., Tanaka M., Yamashita N., Kohjima M., Kotoh K., Nakamuta M., Takayanagi R., Enjoji M., Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease. Hepatology Research 2008 38 11 1122 1129 2-s2.0-53349153430 10.1111/j.1872-034X.2008.00382.x
    • (2008) Hepatology Research , vol.38 , Issue.11 , pp. 1122-1129
    • Higuchi, N.1    Kato, M.2    Shundo, Y.3    Tajiri, H.4    Tanaka, M.5    Yamashita, N.6    Kohjima, M.7    Kotoh, K.8    Nakamuta, M.9    Takayanagi, R.10    Enjoji, M.11
  • 29
    • 33644651160 scopus 로고    scopus 로고
    • Liver X receptors as integrators of metabolic and inflammatory signaling
    • DOI 10.1172/JCI27883
    • Zelcer N., Tontonoz P., Liver X receptors as integrators of metabolic and inflammatory signaling. Journal of Clinical Investigation 2006 116 3 607 614 2-s2.0-33644651160 10.1172/JCI27883 (Pubitemid 43326865)
    • (2006) Journal of Clinical Investigation , vol.116 , Issue.3 , pp. 607-614
    • Zelcer, N.1    Tontonoz, P.2
  • 30
    • 0037324340 scopus 로고    scopus 로고
    • Reciprocal regulation of inflammation and lipid metabolism by liver X receptors
    • DOI 10.1038/nm820
    • Joseph S. B., Castrillo A., Laffitte B. A., Mangelsdorf D. J., Tontonoz P., Reciprocal regulation of inflammation and lipid metabolism by liver X receptors. Nature Medicine 2003 9 2 213 219 2-s2.0-0037324340 10.1038/nm820 (Pubitemid 36227724)
    • (2003) Nature Medicine , vol.9 , Issue.2 , pp. 213-219
    • Joseph, S.B.1    Castrillo, A.2    Laffitte, B.A.3    Mangelsdorf, D.J.4    Tontonoz, P.5
  • 31
    • 0037072732 scopus 로고    scopus 로고
    • Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles
    • 2-s2.0-0037072732 10.1074/jbc.M204887200
    • Grefhorst A., Elzinga B. M., Voshol P. J., Plösch T., Kok T., Bloks V. W., Van Der Sluijs F. H., Havekes L. M., Romijn J. A., Verkade H. J., Kuipers F., Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles. Journal of Biological Chemistry 2002 277 37 34182 34190 2-s2.0-0037072732 10.1074/jbc.M204887200
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.37 , pp. 34182-34190
    • Grefhorst, A.1    Elzinga, B.M.2    Voshol, P.J.3    Plösch, T.4    Kok, T.5    Bloks, V.W.6    Van Der Sluijs, F.H.7    Havekes, L.M.8    Romijn, J.A.9    Verkade, H.J.10    Kuipers, F.11
  • 32
    • 23444431623 scopus 로고    scopus 로고
    • Retinoid X receptor heterodimers in the metabolic syndrome
    • DOI 10.1056/NEJMra043590
    • Shulman A. I., Mangelsdorf D. J., Retinoid X receptor heterodimers in the metabolic syndrome. The New England Journal of Medicine 2005 353 6 604 615 2-s2.0-23444431623 10.1056/NEJMra043590 (Pubitemid 41138942)
    • (2005) New England Journal of Medicine , vol.353 , Issue.6 , pp. 604-615
    • Shulman, A.I.1    Mangelsdorf, D.J.2
  • 33
    • 0013199471 scopus 로고    scopus 로고
    • Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXRα
    • DOI 10.1016/S0092-8674(00)81432-4
    • Peet D. J., Turley S. D., Ma W., Janowski B. A., Lobaccaro J. M. A., Hammer R. E., Mangelsdorf D. J., Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR α Cell 1998 93 5 693 704 2-s2.0-0013199471 10.1016/S0092-8674(00)81432-4 (Pubitemid 28257577)
    • (1998) Cell , vol.93 , Issue.5 , pp. 693-704
    • Peet, D.J.1    Turley, S.D.2    Ma, W.3    Janowski, B.A.4    Lobaccaro, J.-M.A.5    Hammer, R.E.6    Mangelsdorf, D.J.7
  • 34
    • 68049091095 scopus 로고    scopus 로고
    • LXR α activation perturbs hepatic insulin signaling and stimulates production of apolipoprotein B-containing lipoproteins
    • 2-s2.0-68049091095 10.1152/ajpgi.90546.2008
    • Basciano H., Miller A., Baker C., Naples M., Adeli K., LXR α activation perturbs hepatic insulin signaling and stimulates production of apolipoprotein B-containing lipoproteins. The American Journal of Physiology 2009 297 2 G323 G332 2-s2.0-68049091095 10.1152/ajpgi.90546.2008
    • (2009) The American Journal of Physiology , vol.297 , Issue.2
    • Basciano, H.1    Miller, A.2    Baker, C.3    Naples, M.4    Adeli, K.5
  • 35
    • 23744496757 scopus 로고    scopus 로고
    • Adipose development: From stem cell to adipocyte
    • DOI 10.1080/10409230591008189
    • Otto T. C., Lane M. D., Adipose development: from stem cell to adipocyte. Critical Reviews in Biochemistry and Molecular Biology 2005 40 4 229 242 (Pubitemid 41140883)
    • (2005) Critical Reviews in Biochemistry and Molecular Biology , vol.40 , Issue.4 , pp. 229-242
    • Otto, T.C.1    Lane, M.D.2
  • 36
    • 0030961960 scopus 로고    scopus 로고
    • Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells
    • Shimomura I., Shimano H., Horton J. D., Goldstein J. L., Brown M. S., Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells. Journal of Clinical Investigation 1997 99 5 838 845 2-s2.0-0030961960 (Pubitemid 27123619)
    • (1997) Journal of Clinical Investigation , vol.99 , Issue.5 , pp. 838-845
    • Shimomura, I.1    Shimano, H.2    Horton, J.D.3    Goldstein, J.L.4    Brown, M.S.5
  • 37
    • 7044223211 scopus 로고    scopus 로고
    • Maintaining cholesterol homeostasis: Sterol regulatory element-binding proteins
    • Weber L. W., Boll M., Stampfl A., Maintaining cholesterol homeostasis: sterol regulatory element-binding proteins. World Journal of Gastroenterology 2004 10 21 3081 3087 2-s2.0-7044223211 (Pubitemid 39419863)
    • (2004) World Journal of Gastroenterology , vol.10 , Issue.21 , pp. 3081-3087
    • Weber, L.W.1    Boll, M.2    Stampfl, A.3
  • 40
    • 0029797604 scopus 로고    scopus 로고
    • Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a
    • Shimano H., Horton J. D., Hammer R. E., Shimomura I., Brown M. S., Goldstein J. L., Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a. Journal of Clinical Investigation 1996 98 7 1575 1584 2-s2.0-0029797604 (Pubitemid 26327867)
    • (1996) Journal of Clinical Investigation , vol.98 , Issue.7 , pp. 1575-1584
    • Shimano, H.1    Horton, J.D.2    Hammer, R.E.3    Shimomura, I.4    Brown, M.S.5    Goldstein, J.L.6
  • 41
    • 0345448923 scopus 로고    scopus 로고
    • Polyunsaturated Fatty Acids Ameliorate Hepatic Steatosis in Obese Mice by SREBP-1 Suppression
    • DOI 10.1016/j.hep.2003.09.028
    • Sekiya M., Yahagi N., Matsuzaka T., Najima Y., Nakakuki M., Nagai R., Ishibashi S., Osuga J. I., Yamada N., Shimano H., Polyunsaturated fatty acids ameliorate hepatic steatosis in obese mice by SREBP-1 suppression. Hepatology 2003 38 6 1529 1539 2-s2.0-0345448923 10.1016/j.hep.2003.09.028 (Pubitemid 37466979)
    • (2003) Hepatology , vol.38 , Issue.6 , pp. 1529-1539
    • Sekiya, M.1    Yahagi, N.2    Matsuzaka, T.3    Najima, Y.4    Nakakuki, M.5    Nagai, R.6    Ishibashi, S.7    Osuga, J.-I.8    Yamada, N.9    Shimano, H.10


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