ChREBP, a glucose-responsive transcriptional factor, enhances glucose metabolism to support biosynthesis in human cytomegalovirus-infected cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 5, 2014, Pages 1951-1956

  Yu, Yongjun ^a   Maguire, Tobi G ^a   Alwine, James C ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Glycolysis; Lipid synthesis; Viral pathogenesis

Indexed keywords

ACTIN; CARBOHYDRATE RESPONSE ELEMENET BINDING PROTEIN; CARBOHYDRATE RESPONSE ELEMENET BINDING PROTEIN BETA; CARBOHYDRATE RESPONSE ELEMENT BINDING PROTEIN ALPHA; GLUCOSE; GLUCOSE TRANSPORTER 2; GLUCOSE TRANSPORTER 4; LACTIC ACID; NUCLEOTIDE; PHOSPHOTRANSFERASE; PKR LIKE ENDOPLASMIC RETICULUM KINASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; ENZYME INDUCTION; FIBROBLAST; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; LIPID METABOLISM; LIPOGENESIS; METABOLIC REGULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; VIRUS CELL INTERACTION;

GLYCOLYSIS; LIPID SYNTHESIS; VIRAL PATHOGENESIS;

BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; EIF-2 KINASE; FIBROBLASTS; GENE EXPRESSION REGULATION; GLUCOSE; HUMANS; LIPOGENESIS; MALE; MODELS, BIOLOGICAL; NUCLEOTIDES; PROTEIN ISOFORMS; SIGNAL TRANSDUCTION; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRANSCRIPTION FACTORS;

EID: 84893451810     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1310779111     Document Type: Article

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