-
1
-
-
33645223892
-
Insulin-like growth factor-I stimulates H4II rat hepatoma cell proliferation: Dominant role of PI-3=K/Akt signaling
-
Alexia C, Fourmatgeat P, Delautier D, Groyer A. Insulin-like growth factor-I stimulates H4II rat hepatoma cell proliferation: dominant role of PI-3=K/Akt signaling. Exp Cell Res 312: 1142-1152, 2006.
-
(2006)
Exp Cell Res
, vol.312
, pp. 1142-1152
-
-
Alexia, C.1
Fourmatgeat, P.2
Delautier, D.3
Groyer, A.4
-
2
-
-
63449095969
-
Effects of lactational exposure to benzo[alpha] pyrene (B[alpha]P) on postnatal neurodevelopment, neuronal receptor gene expression and behaviour in mice
-
Bouayed J, Desor F, Rammal H, Kiemer AK, Tybl E, Schroeder H, Rychen G, Soulimani R. Effects of lactational exposure to benzo[alpha] pyrene (B[alpha]P) on postnatal neurodevelopment, neuronal receptor gene expression and behaviour in mice. Toxicology 259: 97-106, 2009.
-
(2009)
Toxicology
, vol.259
, pp. 97-106
-
-
Bouayed, J.1
Desor, F.2
Rammal, H.3
Kiemer, A.K.4
Tybl, E.5
Schroeder, H.6
Rychen, G.7
Soulimani, R.8
-
3
-
-
69849087670
-
Genomic and expression profiling of adrenocortical carcinoma: Application to diagnosis, prognosis and treatment
-
Bussey KJ, Demeure MJ. Genomic and expression profiling of adrenocortical carcinoma: application to diagnosis, prognosis and treatment. Future Oncol 5: 641-655, 2009.
-
(2009)
Future Oncol
, vol.5
, pp. 641-655
-
-
Bussey, K.J.1
Demeure, M.J.2
-
4
-
-
70350212686
-
Overactivation of the MEK/ERK pathway in liver tumor cells confers resistance to TGF-β-induced cell death through impairing up-regulation of the NADPH oxidase NOX4
-
Caja L, Sancho P, Bertran E, Iglesias-Serret D, Gil J, Fabregat I. Overactivation of the MEK/ERK pathway in liver tumor cells confers resistance to TGF-β-induced cell death through impairing up-regulation of the NADPH oxidase NOX4. Cancer Res 69: 7595-7602, 2009.
-
(2009)
Cancer Res
, vol.69
, pp. 7595-7602
-
-
Caja, L.1
Sancho, P.2
Bertran, E.3
Iglesias-Serret, D.4
Gil, J.5
Fabregat, I.6
-
5
-
-
0024211360
-
Differential expression of insulin-like growth factor II mRNA in human primary liver cancers, benign liver tumors, and liver cirrhosis
-
Cariani E, Lasserre C, Seurin D, Hamelin B, Kemeny F, Franco D, Czech MP, Ullrich A, Brechot C. Differential expression of insulin-like growth factor II mRNA in human primary liver cancers, benign liver tumors, and liver cirrhosis. Cancer Res 48: 6844-6849, 1988.
-
(1988)
Cancer Res
, vol.48
, pp. 6844-6849
-
-
Cariani, E.1
Lasserre, C.2
Seurin, D.3
Hamelin, B.4
Kemeny, F.5
Franco, D.6
Czech, M.P.7
Ullrich, A.8
Brechot, C.9
-
6
-
-
84856538959
-
The distribution of IGF2 and IMP3 in osteosarcoma and its relationship with angiogenesis
-
Chen P, Wang SJ, Wang HB, Ren P, Wang XQ, Liu WG, Gu WL, Li DQ, Zhang TG, Zhou CJ. The distribution of IGF2 and IMP3 in osteosarcoma and its relationship with angiogenesis. J Mol Histol 43: 63-70, 2012.
-
(2012)
J Mol Histol
, vol.43
, pp. 63-70
-
-
Chen, P.1
Wang, S.J.2
Wang, H.B.3
Ren, P.4
Wang, X.Q.5
Liu, W.G.6
Gu, W.L.7
Li, D.Q.8
Zhang, T.G.9
Zhou, C.J.10
-
7
-
-
81855222056
-
Insulin-like growth factor II mRNA-binding protein 3 expression predicts unfavorable prognosis in patients with neuroblastoma
-
Chen ST, Jeng YM, Chang CC, Chang HH, Huang MC, Juan HF, Hsu CH, Lee H, Liao YF, Lee YL, Hsu WM, Lai HS. Insulin-like growth factor II mRNA-binding protein 3 expression predicts unfavorable prognosis in patients with neuroblastoma. Cancer Sci: 2191-2198, 2011.
-
(2011)
Cancer Sci
, pp. 2191-2198
-
-
Chen, S.T.1
Jeng, Y.M.2
Chang, C.C.3
Chang, H.H.4
Huang, M.C.5
Juan, H.F.6
Hsu, C.H.7
Lee, H.8
Liao, Y.F.9
Lee, Y.L.10
Hsu, W.M.11
Lai, H.S.12
-
8
-
-
27744534653
-
Inhibition of PI3K/Akt signaling: An emerging paradigm for targeted cancer therapy
-
Chen YL, Law PY, Loh HH. Inhibition of PI3K/Akt signaling: an emerging paradigm for targeted cancer therapy. Curr Med Chem Anticancer Agents 5: 575-589, 2005.
-
(2005)
Curr Med Chem Anticancer Agents
, vol.5
, pp. 575-589
-
-
Chen, Y.L.1
Law, P.Y.2
Loh, H.H.3
-
9
-
-
77954435392
-
Loss of imprinting and marked gene elevation are 2 forms of aberrant IGF2 expression in colorectal cancer
-
Cheng YW, Idrees K, Shattock R, Khan SA, Zeng Z, Brennan CW, Paty P, Barany F. Loss of imprinting and marked gene elevation are 2 forms of aberrant IGF2 expression in colorectal cancer. Int J Cancer 127: 568-577, 2010.
-
(2010)
Int J Cancer
, vol.127
, pp. 568-577
-
-
Cheng, Y.W.1
Idrees, K.2
Shattock, R.3
Khan, S.A.4
Zeng, Z.5
Brennan, C.W.6
Paty, P.7
Barany, F.8
-
10
-
-
56449100049
-
The effect of doxorubicin on MEK-ERK signaling predicts its efficacy in HCC
-
Choi J, Yip-Schneider M, Albertin F, Wiesenauer C, Wang Y, Schmidt CM. The effect of doxorubicin on MEK-ERK signaling predicts its efficacy in HCC. J Surg Res 150: 219-226, 2008.
-
(2008)
J Surg Res
, vol.150
, pp. 219-226
-
-
Choi, J.1
Yip-Schneider, M.2
Albertin, F.3
Wiesenauer, C.4
Wang, Y.5
Schmidt, C.M.6
-
11
-
-
70449657762
-
IGF2 mRNAbinding protein 2: Biological function and putative role in type 2 diabetes
-
Christiansen J, Kolte AM, Hansen TVO, Nielsen FC. IGF2 mRNAbinding protein 2: biological function and putative role in type 2 diabetes. J Mol Endocrinol 43: 187-195, 2009.
-
(2009)
J Mol Endocrinol
, vol.43
, pp. 187-195
-
-
Christiansen, J.1
Kolte, A.M.2
Hansen, T.V.O.3
Nielsen, F.C.4
-
12
-
-
79959517565
-
Human fatty liver disease: Old questions and new insights
-
Cohen JC, Horton JD, Hobbs HH. Human fatty liver disease: old questions and new insights. Science 332: 1519-1523, 2011.
-
(2011)
Science
, vol.332
, pp. 1519-1523
-
-
Cohen, J.C.1
Horton, J.D.2
Hobbs, H.H.3
-
13
-
-
0034306450
-
Specificity and mechanism of action of some commonly used protein kinase inhibitors
-
Davies SP, Reddy H, Caivano M, Cohen P. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J 351: 95-105, 2000.
-
(2000)
Biochem J
, vol.351
, pp. 95-105
-
-
Davies, S.P.1
Reddy, H.2
Caivano, M.3
Cohen, P.4
-
14
-
-
33847631240
-
α-Lipoic acid as a directly binding activator of the insulin receptor: Protection from hepatocyte apoptosis
-
Diesel B, Kulhanek-Heinze S, Höltje M, Brandt B, Höltje HD, Vollmar AM, Kiemer AK. α-Lipoic acid as a directly binding activator of the insulin receptor: protection from hepatocyte apoptosis. Biochemistry 46: 2146-2155, 2007.
-
(2007)
Biochemistry
, vol.46
, pp. 2146-2155
-
-
Diesel, B.1
Kulhanek-Heinze, S.2
Höltje, M.3
Brandt, B.4
Höltje, H.D.5
Vollmar, A.M.6
Kiemer, A.K.7
-
15
-
-
34250814465
-
Expression of oncofetal RNA-binding protein CRD-BP/IMP1 predicts clinical outcome in colon cancer
-
Dimitriadis E, Trangas T, Milatos S, Foukas PG, Gioulbasanis I, Courtis N, Nielsen FC, Pandis N, Dafni U, Bardi G, Ioannidis P. Expression of oncofetal RNA-binding protein CRD-BP/IMP1 predicts clinical outcome in colon cancer. Int J Cancer 121: 486-494, 2007.
-
(2007)
Int J Cancer
, vol.121
, pp. 486-494
-
-
Dimitriadis, E.1
Trangas, T.2
Milatos, S.3
Foukas, P.G.4
Gioulbasanis, I.5
Courtis, N.6
Nielsen, F.C.7
Pandis, N.8
Dafni, U.9
Bardi, G.10
Ioannidis, P.11
-
16
-
-
34250892541
-
ERK1/2-dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl-1 and Bcl-xL
-
Ewings KE, Hadfield-Moorhouse K, Wiggins CM, Wickenden JA, Balmanno K, Gilley R, Degenhardt K, White E, Cook SJ. ERK1/2-dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl-1 and Bcl-xL. EMBO J 26: 2856-2867, 2007.
-
(2007)
EMBO J
, vol.26
, pp. 2856-2867
-
-
Ewings, K.E.1
Hadfield-Moorhouse, K.2
Wiggins, C.M.3
Wickenden, J.A.4
Balmanno, K.5
Gilley, R.6
Degenhardt, K.7
White, E.8
Cook, S.J.9
-
17
-
-
34247602670
-
Survival and apoptosis: A dysregulated balance in liver cancer
-
Fabregat I, Roncero C, Fernández M. Survival and apoptosis: a dysregulated balance in liver cancer. Liver Int 27: 155-162, 2007.
-
(2007)
Liver Int
, vol.27
, pp. 155-162
-
-
Fabregat, I.1
Roncero, C.2
Fernández, M.3
-
18
-
-
11844272574
-
Atrial natriuretic peptide induces mitogenactivated protein kinase phosphatase-1 in human endothelial cells via Rac1 and NAD(P)H oxidase/Nox2-activation
-
Fürst R, Brueckl C, Kuebler WM, Zahler S, Krötz F, Görlach A, Vollmar AM, Kiemer AK. Atrial natriuretic peptide induces mitogenactivated protein kinase phosphatase-1 in human endothelial cells via Rac1 and NAD(P)H oxidase/Nox2-activation. Circ Res 96: 43-53, 2005.
-
(2005)
Circ Res
, vol.96
, pp. 43-53
-
-
Fürst, R.1
Brueckl, C.2
Kuebler, W.M.3
Zahler, S.4
Krötz, F.5
Görlach, A.6
Vollmar, A.M.7
Kiemer, A.K.8
-
19
-
-
21044445452
-
Apoptosis: A mechanism of acute and chronic liver injury
-
Guicciardi ME, Gores GJ. Apoptosis: a mechanism of acute and chronic liver injury. Gut 54: 1024-1033, 2005.
-
(2005)
Gut
, vol.54
, pp. 1024-1033
-
-
Guicciardi, M.E.1
Gores, G.J.2
-
20
-
-
57749083495
-
Hepatitis B virus-induced hFGL2 transcription is dependent on c-Ets-2 and MAPK signal pathway
-
Han M, Yan W, Guo W, Xi D, Zhou Y, Li W, Gao S, Liu M, Levy G, Luo X, Ning Q. Hepatitis B virus-induced hFGL2 transcription is dependent on c-Ets-2 and MAPK signal pathway. J Biol Chem 283: 32715-32729, 2008.
-
(2008)
J Biol Chem
, vol.283
, pp. 32715-32729
-
-
Han, M.1
Yan, W.2
Guo, W.3
Xi, D.4
Zhou, Y.5
Li, W.6
Gao, S.7
Liu, M.8
Levy, G.9
Luo, X.10
Ning, Q.11
-
21
-
-
2942534884
-
Dwarfism and impaired gut development in insulin-like growth factor II mRNA-binding protein 1-deficient mice
-
Hansen TVO, Hammer NA, Nielsen J, Madsen M, Dalbaeck C, Wewer UM, Christiansen J, Nielsen FC. Dwarfism and impaired gut development in insulin-like growth factor II mRNA-binding protein 1-deficient mice. Mol Cell Biol 24: 4448-4464, 2004.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 4448-4464
-
-
Hansen, T.V.O.1
Hammer, N.A.2
Nielsen, J.3
Madsen, M.4
Dalbaeck, C.5
Wewer, U.M.6
Christiansen, J.7
Nielsen, F.C.8
-
22
-
-
70349568358
-
A lymphotoxin-driven pathway to hepatocellular carcinoma
-
Haybaeck J, Zeller N, Wolf MJ, Weber A, Wagner U, Kurrer MO, Bremer J, Iezzi G, Graf R, Clavien PA, Thimme R, Blum H, Nedospasov SA, Zatloukal K, Ramzan M, Ciesek S, Pietschmann T, Marche PN, Karin M, Kopf M, Browning JL, Aguzzi A, Heikenwalder M. A lymphotoxin-driven pathway to hepatocellular carcinoma. Cancer Cell 16: 295-308, 2009.
-
(2009)
Cancer Cell
, vol.16
, pp. 295-308
-
-
Haybaeck, J.1
Zeller, N.2
Wolf, M.J.3
Weber, A.4
Wagner, U.5
Kurrer, M.O.6
Bremer, J.7
Iezzi, G.8
Graf, R.9
Clavien, P.A.10
Thimme, R.11
Blum, H.12
Nedospasov, S.A.13
Zatloukal, K.14
Ramzan, M.15
Ciesek, S.16
Pietschmann, T.17
Marche, P.N.18
Karin, M.19
Kopf, M.20
Browning, J.L.21
Aguzzi, A.22
Heikenwalder, M.23
more..
-
23
-
-
77749252612
-
Medical oncology: IMP3 is a novel prognostic marker for colon cancer
-
Hutchinson L. Medical oncology: IMP3 is a novel prognostic marker for colon cancer. Nat Rev Clin Oncol 7: 123, 2010.
-
(2010)
Nat Rev Clin Oncol
, vol.7
, pp. 123
-
-
Hutchinson, L.1
-
24
-
-
2542473135
-
Over-expression of the mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK in hepatocellular carcinoma: Its role in tumor progression and apoptosis
-
Huynh H, Nguyen TTT, Chow KHP, Tan PH, Soo KC, Tran E. Over-expression of the mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK in hepatocellular carcinoma: Its role in tumor progression and apoptosis. BMC Gastroenterol 3: 19, 2003.
-
(2003)
BMC Gastroenterol
, vol.3
, pp. 19
-
-
Huynh, H.1
Nguyen, T.T.T.2
Chow, K.H.P.3
Tan, P.H.4
Soo, K.C.5
Tran, E.6
-
25
-
-
77954061302
-
Insulin-like growth factor II mRNA binding protein 3 (IMP3) is overexpressed in prostate cancer and correlates with higher Gleason scores
-
Ikenberg K, Fritzsche FR, Zuerrer-Haerdi U, Hofmann I, Hermanns T, Seifert H, Müntener M, Provenzano M, Sulser T, Behnke S, Gerhardt J, Mortezavi A, Wild P, Hofstädter F, Burger M, Moch H, Kristiansen G. Insulin-like growth factor II mRNA binding protein 3 (IMP3) is overexpressed in prostate cancer and correlates with higher Gleason scores. BMC Cancer 10: 341, 2010.
-
(2010)
BMC Cancer
, vol.10
, pp. 341
-
-
Ikenberg, K.1
Fritzsche, F.R.2
Zuerrer-Haerdi, U.3
Hofmann, I.4
Hermanns, T.5
Seifert, H.6
Müntener, M.7
Provenzano, M.8
Sulser, T.9
Behnke, S.10
Gerhardt, J.11
Mortezavi, A.12
Wild, P.13
Hofstädter, F.14
Burger, M.15
Moch, H.16
Kristiansen, G.17
-
26
-
-
54449087536
-
RNA-binding protein insulin-like growth factor II mRNA-binding protein 3 expression promotes tumor invasion and predicts early recurrence and poor prognosis in hepatocellular carcinoma
-
Jeng YM, Chang CC, Hu FC, Chou HY, Kao HL, Wang TH, Hsu HC. RNA-binding protein insulin-like growth factor II mRNA-binding protein 3 expression promotes tumor invasion and predicts early recurrence and poor prognosis in hepatocellular carcinoma. Hepatology 48: 1118-1127, 2008.
-
(2008)
Hepatology
, vol.48
, pp. 1118-1127
-
-
Jeng, Y.M.1
Chang, C.C.2
Hu, F.C.3
Chou, H.Y.4
Kao, H.L.5
Wang, T.H.6
Hsu, H.C.7
-
27
-
-
69949160176
-
Tumor-suppressive lipoxygenases inhibit the expression of c-myc mRNA coding region determinant-binding protein/ insulin-like growth factor II mRNA-binding protein 1 in human prostate carcinoma PC-3 cells
-
Kawakami Y, Kubota N, Ekuni N, Suzuki-Yamamoto T, Kimoto M, Yamashita H, Tsuji H, Yoshimoto T, Jisaka M, Tanaka J, Fujimura HF, Miwa Y, Takahashi Y. Tumor-suppressive lipoxygenases inhibit the expression of c-myc mRNA coding region determinant-binding protein/ insulin-like growth factor II mRNA-binding protein 1 in human prostate carcinoma PC-3 cells. Biosci Biotechnol Biochem 73: 1811-1817, 2009.
-
(2009)
Biosci Biotechnol Biochem
, vol.73
, pp. 1811-1817
-
-
Kawakami, Y.1
Kubota, N.2
Ekuni, N.3
Suzuki-Yamamoto, T.4
Kimoto, M.5
Yamashita, H.6
Tsuji, H.7
Yoshimoto, T.8
Jisaka, M.9
Tanaka, J.10
Fujimura, H.F.11
Miwa, Y.12
Takahashi, Y.13
-
28
-
-
36749086451
-
Expression of the RNA-binding protein IMP1 correlates with poor prognosis in ovarian carcinoma
-
Kobel M, Weidensdorfer D, Reinke C, Lederer M, Schmitt WD, Zeng K, Thomssen C, Hauptmann S, Huttelmaier S. Expression of the RNA-binding protein IMP1 correlates with poor prognosis in ovarian carcinoma. Oncogene 26: 7584-7589, 2007.
-
(2007)
Oncogene
, vol.26
, pp. 7584-7589
-
-
Kobel, M.1
Weidensdorfer, D.2
Reinke, C.3
Lederer, M.4
Schmitt, W.D.5
Zeng, K.6
Thomssen, C.7
Hauptmann, S.8
Huttelmaier, S.9
-
29
-
-
4344566974
-
Protein kinase A dependent signalling mediates antiapoptotic effects of the atrial natriuretic peptide in ischemic livers
-
Kulhanek-Heinze S, Gerbes AL, Gerwig T, Vollmar AM, Kiemer AK. Protein kinase A dependent signalling mediates antiapoptotic effects of the atrial natriuretic peptide in ischemic livers. J Hepatol 41: 414-420, 2004.
-
(2004)
J Hepatol
, vol.41
, pp. 414-420
-
-
Kulhanek-Heinze, S.1
Gerbes, A.L.2
Gerwig, T.3
Vollmar, A.M.4
Kiemer, A.K.5
-
30
-
-
34547469939
-
Raf kinases: Function, regulation and role in human cancer
-
Leicht DT, Balan V, Kaplun A, Singh-Gupta V, Kaplun L, Dobson M, Tzivion G. Raf kinases: function, regulation and role in human cancer. Biochim Biophys Acta 1773: 1196-1212, 2007.
-
(2007)
Biochim Biophys Acta
, vol.1773
, pp. 1196-1212
-
-
Leicht, D.T.1
Balan, V.2
Kaplun, A.3
Singh-Gupta, V.4
Kaplun, L.5
Dobson, M.6
Tzivion, G.7
-
31
-
-
74949105194
-
Insulin-like growth factor 2 and the insulin receptor, but not insulin, regulate fetal hepatic glycogen synthesis
-
Liang L, Guo WH, Esquiliano DR, Asai M, Rodriguez S, Giraud J, Kushner JA, White MF, Lopez MF. Insulin-like growth factor 2 and the insulin receptor, but not insulin, regulate fetal hepatic glycogen synthesis. Endocrinology 151: 741-747, 2010.
-
(2010)
Endocrinology
, vol.151
, pp. 741-747
-
-
Liang, L.1
Guo, W.H.2
Esquiliano, D.R.3
Asai, M.4
Rodriguez, S.5
Giraud, J.6
Kushner, J.A.7
White, M.F.8
Lopez, M.F.9
-
32
-
-
80052406934
-
RNA-binding protein insulin-like growth factor mRNA-binding protein 3 (IMP-3) promotes cell survival via insulin-like growth factor II signaling after ionizing radiation
-
Liao B, Hu Y, Brewer G. RNA-binding protein insulin-like growth factor mRNA-binding protein 3 (IMP-3) promotes cell survival via insulin-like growth factor II signaling after ionizing radiation. J Biol Chem 286: 31145-31152, 2011.
-
(2011)
J Biol Chem
, vol.286
, pp. 31145-31152
-
-
Liao, B.1
Hu, Y.2
Brewer, G.3
-
33
-
-
0030914080
-
Hepatocarcinogenesis in woodchuck hepatitis virus/c-myc mice: Sustained cell proliferation and biphasic activation of insulin-like growth factor II
-
Liu P, Terradillos O, Renard CA, Feldmann G, Buendia MA, Bernuau D. Hepatocarcinogenesis in woodchuck hepatitis virus/c-myc mice: sustained cell proliferation and biphasic activation of insulin-like growth factor II. Hepatology 25: 874-883, 1997.
-
(1997)
Hepatology
, vol.25
, pp. 874-883
-
-
Liu, P.1
Terradillos, O.2
Renard, C.A.3
Feldmann, G.4
Buendia, M.A.5
Bernuau, D.6
-
34
-
-
0034856833
-
Aberrant expression of fetal RNA-binding protein p62 in liver cancer and liver cirrhosis
-
Lu M, Nakamura RM, Dent ED, Zhang JY, Nielsen FC, Christiansen J, Chan EKL, Tan EM. Aberrant expression of fetal RNA-binding protein p62 in liver cancer and liver cirrhosis. Am J Pathol 159: 945-953, 2001.
-
(2001)
Am J Pathol
, vol.159
, pp. 945-953
-
-
Lu, M.1
Nakamura, R.M.2
Dent, E.D.3
Zhang, J.Y.4
Nielsen, F.C.5
Christiansen, J.6
Chan, E.K.L.7
Tan, E.M.8
-
35
-
-
22644433562
-
Expression and significance of tumor-related genes in HCC
-
Lu ZL, Luo DZ, Wen JM. Expression and significance of tumor-related genes in HCC. World J Gastroenterol 11: 3850-3854, 2005.
-
(2005)
World J Gastroenterol
, vol.11
, pp. 3850-3854
-
-
Lu, Z.L.1
Luo, D.Z.2
Wen, J.M.3
-
36
-
-
80051733060
-
One-step preservation of phosphoproteins and tissue morphology at room temperature for diagnostic and research specimens
-
Mueller C, Edmiston KH, Carpenter C, Gaffney E, Ryan C, Ward R, White S, Memeo L, Colarossi C, Petricoin EF III, Liotta LA, Espina V. One-step preservation of phosphoproteins and tissue morphology at room temperature for diagnostic and research specimens. PLoS ONE 6: e23780, 2011.
-
(2011)
PLoS ONE
, vol.6
-
-
Mueller, C.1
Edmiston, K.H.2
Carpenter, C.3
Gaffney, E.4
Ryan, C.5
Ward, R.6
White, S.7
Memeo, L.8
Colarossi, C.9
Petricoin III, E.F.10
Liotta, L.A.11
Espina, V.12
-
37
-
-
0027085619
-
The molecular and cellular biology of insulin-like growth factor II
-
Nielsen FC. The molecular and cellular biology of insulin-like growth factor II. Prog Growth Factor Res 4: 257-290, 1992.
-
(1992)
Prog Growth Factor Res
, vol.4
, pp. 257-290
-
-
Nielsen, F.C.1
-
39
-
-
0035575999
-
Apoptosis and proliferation in hepatocarcinogenesis related to cirrhosis
-
Park YN, Chae KJ, Kim YB, Park C, Theise N. Apoptosis and proliferation in hepatocarcinogenesis related to cirrhosis. Cancer 92: 2733-2738, 2001.
-
(2001)
Cancer
, vol.92
, pp. 2733-2738
-
-
Park, Y.N.1
Chae, K.J.2
Kim, Y.B.3
Park, C.4
Theise, N.5
-
41
-
-
77952646004
-
Identification of an autoantibody panel to separate lung cancer from smokers and nonsmokers
-
Rom WN, Goldberg JD, Addrizzo-Harris D, Watson HN, Khilkin M, Greenberg AK, Naidich DP, Crawford B, Eylers E, Liu D, Tan EM. Identification of an autoantibody panel to separate lung cancer from smokers and nonsmokers. BMC Cancer 10: 234, 2010.
-
(2010)
BMC Cancer
, vol.10
, pp. 234
-
-
Rom, W.N.1
Goldberg, J.D.2
Addrizzo-Harris, D.3
Watson, H.N.4
Khilkin, M.5
Greenberg, A.K.6
Naidich, D.P.7
Crawford, B.8
Eylers, E.9
Liu, D.10
Tan, E.M.11
-
42
-
-
0346725866
-
The role of the IGF axis in hepatocarcinogenesis
-
Scharf JG, Braulke T. The role of the IGF axis in hepatocarcinogenesis. Horm Metab Res 35: 685-693, 2003.
-
(2003)
Horm Metab Res
, vol.35
, pp. 685-693
-
-
Scharf, J.G.1
Braulke, T.2
-
43
-
-
0026635934
-
Reactivation of insulin-like growth factor II during hepatocarcinogenesis in transgenic mice suggests a role in malignant growth
-
Schirmacher P, Held WA, Yang D, Chisari FV, Rustum Y, Rogler CE. Reactivation of insulin-like growth factor II during hepatocarcinogenesis in transgenic mice suggests a role in malignant growth. Cancer Res 52: 2549-2556, 1992.
-
(1992)
Cancer Res
, vol.52
, pp. 2549-2556
-
-
Schirmacher, P.1
Held, W.A.2
Yang, D.3
Chisari, F.V.4
Rustum, Y.5
Rogler, C.E.6
-
44
-
-
36549013178
-
Activation of the ERK and AKT signalling pathway predicts poor prognosis in hepatocellular carcinoma and ERK activation in cancer tissue is associated with hepatitis C virus infection
-
Schmitz KJ, Wohlschlaeger J, Lang H, Sotiropoulos GC, Malago M, Steveling K, Reis H, Cicinnati VR, Schmid KW, Baba HA. Activation of the ERK and AKT signalling pathway predicts poor prognosis in hepatocellular carcinoma and ERK activation in cancer tissue is associated with hepatitis C virus infection. J Hepatol 48: 83-90, 2008.
-
(2008)
J Hepatol
, vol.48
, pp. 83-90
-
-
Schmitz, K.J.1
Wohlschlaeger, J.2
Lang, H.3
Sotiropoulos, G.C.4
Malago, M.5
Steveling, K.6
Reis, H.7
Cicinnati, V.R.8
Schmid, K.W.9
Baba, H.A.10
-
45
-
-
0015752890
-
Preparation of rat liver cells. III. Enzymatic requirements for tissue dispersion
-
Seglen PO. Preparation of rat liver cells. III. Enzymatic requirements for tissue dispersion. Exp Cell Res 82: 391-398, 1973.
-
(1973)
Exp Cell Res
, vol.82
, pp. 391-398
-
-
Seglen, P.O.1
-
46
-
-
77956198486
-
IGF2 is highly expressed in pediatric undifferentiated sarcomas and reveals two distinct cytoplasmic trafficking patterns
-
Somers GR, Michael HO, Pienkowska M, Shlien A, Malkin D, Ackerley C, Zielenska M. IGF2 is highly expressed in pediatric undifferentiated sarcomas and reveals two distinct cytoplasmic trafficking patterns. Pediatr Dev Pathol 13: 169-177, 2010.
-
(2010)
Pediatr Dev Pathol
, vol.13
, pp. 169-177
-
-
Somers, G.R.1
Michael, H.O.2
Pienkowska, M.3
Shlien, A.4
Malkin, D.5
Ackerley, C.6
Zielenska, M.7
-
47
-
-
5044228741
-
Mechanisms regulating the constitutive activation of the extracellular signal-regulated kinase (ERK) signaling pathway in ovarian cancer and the effect of ribonucleic acid interference for ERK1/2 on cancer cell proliferation
-
Steinmetz R, Wagoner HA, Zeng P, Hammond JR, Hannon TS, Meyers JL, Pescovitz OH. Mechanisms regulating the constitutive activation of the extracellular signal-regulated kinase (ERK) signaling pathway in ovarian cancer and the effect of ribonucleic acid interference for ERK1/2 on cancer cell proliferation. Mol Endocrinol 18: 2570-2582, 2004.
-
(2004)
Mol Endocrinol
, vol.18
, pp. 2570-2582
-
-
Steinmetz, R.1
Wagoner, H.A.2
Zeng, P.3
Hammond, J.R.4
Hannon, T.S.5
Meyers, J.L.6
Pescovitz, O.H.7
-
48
-
-
21344461266
-
The diversity expression of p62 in digestive system cancers
-
Su Y, Qian H, Zhang J, Wang S, Shi P, Peng X. The diversity expression of p62 in digestive system cancers. Clin Immunol 116: 118-123, 2005.
-
(2005)
Clin Immunol
, vol.116
, pp. 118-123
-
-
Su, Y.1
Qian, H.2
Zhang, J.3
Wang, S.4
Shi, P.5
Peng, X.6
-
49
-
-
44349169446
-
Influence of risk factors for metabolic syndrome and non-alcoholic fatty liver disease on the progression and prognosis of hepatocellular carcinoma
-
Takamatsu S, Noguchi N, Kudoh A, Nakamura N, Kawamura T, Teramoto K, Igari T, Arii S. Influence of risk factors for metabolic syndrome and non-alcoholic fatty liver disease on the progression and prognosis of hepatocellular carcinoma. Hepatogastroenterology 55: 609-614, 2008.
-
(2008)
Hepatogastroenterology
, vol.55
, pp. 609-614
-
-
Takamatsu, S.1
Noguchi, N.2
Kudoh, A.3
Nakamura, N.4
Kawamura, T.5
Teramoto, K.6
Igari, T.7
Arii, S.8
-
50
-
-
0036699940
-
Molecular pathogenesis of human hepatocellular carcinoma
-
Thorgeirsson SS, Grisham JW. Molecular pathogenesis of human hepatocellular carcinoma. Nat Genet 31: 339-346, 2002.
-
(2002)
Nat Genet
, vol.31
, pp. 339-346
-
-
Thorgeirsson, S.S.1
Grisham, J.W.2
-
51
-
-
77949875878
-
IGF activation in a molecular subclass of hepatocellular carcinoma and pre-clinical efficacy of IGF-1R blockage
-
Tovar V, Alsinet C, Villanueva A, Hoshida Y, Chiang DY, Solé M, Thung S, Moyano S, Toffanin S, Mínguez B, Cabellos L, Peix J, Schwartz M, Mazzaferro V, Bruix J, Llovet JM. IGF activation in a molecular subclass of hepatocellular carcinoma and pre-clinical efficacy of IGF-1R blockage. J Hepatol 52: 550-559, 2010.
-
(2010)
J Hepatol
, vol.52
, pp. 550-559
-
-
Tovar, V.1
Alsinet, C.2
Villanueva, A.3
Hoshida, Y.4
Chiang, D.Y.5
Solé, M.6
Thung, S.7
Moyano, S.8
Toffanin, S.9
Mínguez, B.10
Cabellos, L.11
Peix, J.12
Schwartz, M.13
Mazzaferro, V.14
Bruix, J.15
Llovet, J.M.16
-
52
-
-
79954648698
-
Overexpression of the IGF2-mRNA binding protein p62 in transgenic mice induces a steatotic phenotype
-
Tybl E, Shi FD, Kessler SM, Tierling S, Walter J, Bohle RM, Wieland S, Zhang J, Tan EM, Kiemer AK. Overexpression of the IGF2-mRNA binding protein p62 in transgenic mice induces a steatotic phenotype. J Hepatol 54: 994-1001, 2011.
-
(2011)
J Hepatol
, vol.54
, pp. 994-1001
-
-
Tybl, E.1
Shi, F.D.2
Kessler, S.M.3
Tierling, S.4
Walter, J.5
Bohle, R.M.6
Wieland, S.7
Zhang, J.8
Tan, E.M.9
Kiemer, A.K.10
-
53
-
-
77956627711
-
The role of signaling pathways in the development and treatment of hepatocellular carcinoma
-
Whittaker S, Marais R, Zhu AX. The role of signaling pathways in the development and treatment of hepatocellular carcinoma. Oncogene 29: 4989-5005, 2010.
-
(2010)
Oncogene
, vol.29
, pp. 4989-5005
-
-
Whittaker, S.1
Marais, R.2
Zhu, A.X.3
-
54
-
-
65549088474
-
Down-regulation of extracellular signal-regulated kinase 1/2 activity in P-glycoprotein-mediated multidrug resistant hepatocellular carcinoma cells
-
Yan F, Wang XM, Pan C, Ma QM. Down-regulation of extracellular signal-regulated kinase 1/2 activity in P-glycoprotein-mediated multidrug resistant hepatocellular carcinoma cells. World J Gastroenterol 15: 1443-1451, 2009.
-
(2009)
World J Gastroenterol
, vol.15
, pp. 1443-1451
-
-
Yan, F.1
Wang, X.M.2
Pan, C.3
Ma, Q.M.4
-
55
-
-
0037243999
-
A methylated oligonucleotide inhibits IGF2 expression and enhances survival in a model of hepatocellular carcinoma
-
Yao X, Hu JF, Daniels M, Shiran H, Zhou X, Yan H, Lu H, Zeng Z, Wang Q, Li T, Hoffman AR. A methylated oligonucleotide inhibits IGF2 expression and enhances survival in a model of hepatocellular carcinoma. J Clin Invest 111: 265-273, 2003.
-
(2003)
J Clin Invest
, vol.111
, pp. 265-273
-
-
Yao, X.1
Hu, J.F.2
Daniels, M.3
Shiran, H.4
Zhou, X.5
Yan, H.6
Lu, H.7
Zeng, Z.8
Wang, Q.9
Li, T.10
Hoffman, A.R.11
-
56
-
-
0033526101
-
A novel cytoplasmic protein with RNA-binding motifs is an autoantigen in human hepatocellular carcinoma
-
Zhang JY, Chan EKL, Peng XX, Tan EM. A novel cytoplasmic protein with RNA-binding motifs is an autoantigen in human hepatocellular carcinoma. J Exp Med 189: 1101-1110, 1999.
-
(1999)
J Exp Med
, vol.189
, pp. 1101-1110
-
-
Zhang, J.Y.1
Chan, E.K.L.2
Peng, X.X.3
Tan, E.M.4
-
57
-
-
1542509671
-
Autoantibodies to IGF-II mRNA binding protein p62 and overexpression of p62 in human hepatocellular carcinoma
-
Zhang J, Chan EKL. Autoantibodies to IGF-II mRNA binding protein p62 and overexpression of p62 in human hepatocellular carcinoma. Autoimmun Rev 1: 146-153, 2002.
-
(2002)
Autoimmun Rev
, vol.1
, pp. 146-153
-
-
Zhang, J.1
Chan, E.K.L.2
-
58
-
-
0034900847
-
Autoimmune responses to mRNA binding proteins p62 and Koc in diverse malignancies
-
Zhang JY, Chan EKL, Peng XX, Lu M, Wang X, Mueller F, Tan EM. Autoimmune responses to mRNA binding proteins p62 and Koc in diverse malignancies. Clin Immunol 100: 149-156, 2001.
-
(2001)
Clin Immunol
, vol.100
, pp. 149-156
-
-
Zhang, J.Y.1
Chan, E.K.L.2
Peng, X.X.3
Lu, M.4
Wang, X.5
Mueller, F.6
Tan, E.M.7
-
59
-
-
15044359246
-
Hepatitis C virus E2 protein promotes human hepatoma cell proliferation through the MAPK/ERK signaling pathway via cellular receptors
-
Zhao LJ, Wang L, Ren H, Cao J, Li L, Ke JS, Qi ZT. Hepatitis C virus E2 protein promotes human hepatoma cell proliferation through the MAPK/ERK signaling pathway via cellular receptors. Exp Cell Res 305: 23-32, 2005.
-
(2005)
Exp Cell Res
, vol.305
, pp. 23-32
-
-
Zhao, L.J.1
Wang, L.2
Ren, H.3
Cao, J.4
Li, L.5
Ke, J.S.6
Qi, Z.T.7
|