ROS-mediated autophagy induced by dysregulation of lipid metabolism plays a protective role in colorectal cancer cells treated with gambogic acid

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Zhang, Haiyuan ^a   Lei, Yunlong ^b   Yuan, Ping ^a   Li, Lingjun ^a   Luo, Chao ^a   Gao, Rui ^a   Tian, Jun ^a   Feng, Zuohua ^a   Nice, Edouard C ^c   Sun, Jun ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b CHONGQING MEDICAL UNIVERSITY   (China)

^c MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONATE 5 LIPOXYGENASE; GAMBOGIC ACID; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; ANTINEOPLASTIC AGENT; XANTHONE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER INHIBITION; COLORECTAL CANCER; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIPID METABOLISM; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION REDUCTION REACTION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; COLORECTAL NEOPLASMS; DRUG EFFECTS; METABOLISM; PHYSIOLOGY; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; AUTOPHAGY; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; HUMANS; LIPID METABOLISM; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; XANTHONES;

EID: 84901481056     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0096418     Document Type: Article

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