Cluvenone induces apoptosis via a direct target in mitochondria: A possible mechanism to circumvent chemo-resistance?

Investigational New Drugs

Volumn 30, Issue 5, 2012, Pages 1841-1848

  Guizzunti, Gianni ^a   Theodorakis, Emmanuel A ^b   Yu, Alice L ^b,c   Zurzolo, Chiara ^a   Batova, Ayse ^b  

^a INSTITUT PASTEUR   (France)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c GENOMICS RESEARCH CENTER   (Taiwan)

Author keywords

Apoptosis; Cluvenone; Garcinia; Mitocan; Mitochondria; Xanthone

Indexed keywords

BENZYLOXYCARBONYLLEUCYLGLUTAMYLHISTIDYLASPARTYL FLUOROMETHYL KETONE; CASPASE 9; CLUVENONE; CYTOCHROME C; GAMBOGIC ACID; UNCLASSIFIED DRUG; XANTHONE DERIVATIVE;

APOPTOSIS; ARTICLE; CANCER RESISTANCE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOSOL; DRUG CYTOTOXICITY; DRUG TARGETING; GARCINIA; HELA CELL; LEUKEMIA CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; PRIORITY JOURNAL;

APOPTOSIS; CASPASE 9; CELL LINE, TUMOR; CYTOCHROMES C; DRUG RESISTANCE, NEOPLASM; HELA CELLS; HUMANS; LEUKEMIA; MITOCHONDRIA; XANTHONES;

EID: 84867887208     PISSN: 01676997     EISSN: 15730646     Source Type: Journal    
DOI: 10.1007/s10637-011-9745-y     Document Type: Article

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