Cytotoxic effect of gambogic acid on SH-SY5Y neuroblastoma cells is mediated by intrinsic caspase-dependent signaling pathway

Molecular and Cellular Biochemistry

Volumn 377, Issue 1-2, 2013, Pages 187-196

  Rahman, Md Ataur ^a   Kim, Nam Ho ^a   Huh, Sung Oh ^a  

^a Hallym University   (South Korea)

Author keywords

Anticancer; Apoptosis; Bcl 2 family; Caspase; Gambogic acid; Neuroblastoma

Indexed keywords

CASPASE; CASPASE 3; CASPASE 9; FAS ANTIGEN; FAS LIGAND; GAMBOGIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE; PROCASPASE 9; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN KINASE B; PROTEIN MCL 1;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL DAMAGE; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; DENSITOMETRY; DNA FRAGMENTATION; DOWN REGULATION; DRUG CYTOTOXICITY; FIBROBLAST; HUMAN; HUMAN CELL; IC 50; INCUBATION TIME; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; TUMOR CELL; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 3; CASPASE 9; CELL LINE, TUMOR; CELL SHAPE; CELL SURVIVAL; DNA FRAGMENTATION; DRUGS, CHINESE HERBAL; ENZYME ACTIVATION; FIBROBLASTS; GLYCOGEN SYNTHASE KINASE 3; HUMANS; NEUROBLASTOMA; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; XANTHONES;

CLUSIACEAE; GARCINIA HANBURYI;

EID: 84875642285     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-013-1584-z     Document Type: Article

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