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Volumn 67, Issue 1, 2013, Pages 199-206

Gambogic Acid Sensitizes Ovarian Cancer Cells to Doxorubicin Through ROS-Mediated Apoptosis

Author keywords

Doxorubicin; Gambogic acid; Ovarian cancer; ROS; Synergistic effect

Indexed keywords

MUS;

EID: 84883456542     PISSN: 10859195     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12013-013-9534-7     Document Type: Article
Times cited : (42)

References (50)
  • 1
    • 4344684641 scopus 로고    scopus 로고
    • Proteomics and ovarian cancer: implications for diagnosis and treatment: a critical review of the recent literature
    • Posadas, E. M., Davidson, B., & Kohn, E. C. (2004). Proteomics and ovarian cancer: implications for diagnosis and treatment: a critical review of the recent literature. Current Opinion in Oncology, 16, 478-484.
    • (2004) Current Opinion in Oncology , vol.16 , pp. 478-484
    • Posadas, E.M.1    Davidson, B.2    Kohn, E.C.3
  • 5
    • 39749171410 scopus 로고    scopus 로고
    • Early events in the pathogenesis of epithelial ovarian cancer
    • Landen, C. N, Jr, Birrer, M. J., & Sood, A. K. (2008). Early events in the pathogenesis of epithelial ovarian cancer. Journal of Clinical Oncology, 26, 995-1005.
    • (2008) Journal of Clinical Oncology , vol.26 , pp. 995-1005
    • Landen Jr., C.N.1    Birrer, M.J.2    Sood, A.K.3
  • 6
  • 7
    • 0035013358 scopus 로고    scopus 로고
    • The clinical utility of liposomal doxorubicin in recurrent ovarian cancer
    • Campos, S. M., Penson, R. T., Mays, A. R., et al. (2001). The clinical utility of liposomal doxorubicin in recurrent ovarian cancer. Gynecologic Oncology, 81, 206-212.
    • (2001) Gynecologic Oncology , vol.81 , pp. 206-212
    • Campos, S.M.1    Penson, R.T.2    Mays, A.R.3
  • 8
    • 79960104514 scopus 로고    scopus 로고
    • Gambogic acid inhibits STAT3 phosphorylation through activation of protein tyrosine phosphatase SHP-1: potential role in proliferation and apoptosis
    • Prasad, S., Pandey, M. K., Yadav, V. R., & Aggarwal, B. B. (2011). Gambogic acid inhibits STAT3 phosphorylation through activation of protein tyrosine phosphatase SHP-1: potential role in proliferation and apoptosis. Cancer prevention research (Philadelphia, Pa.), 4, 1084-1094.
    • (2011) Cancer Prevention Research (Philadelphia, Pa.) , vol.4 , pp. 1084-1094
    • Prasad, S.1    Pandey, M.K.2    Yadav, V.R.3    Aggarwal, B.B.4
  • 9
    • 0036964816 scopus 로고    scopus 로고
    • Chemopreventive agents induce suppression of nuclear factor-kappaB leading to chemosensitization
    • Bharti, A. C., & Aggarwal, B. B. (2002). Chemopreventive agents induce suppression of nuclear factor-kappaB leading to chemosensitization. Annals of the New York Academy of Sciences, 973, 392-395.
    • (2002) Annals of the New York Academy of Sciences , vol.973 , pp. 392-395
    • Bharti, A.C.1    Aggarwal, B.B.2
  • 10
    • 34047249406 scopus 로고    scopus 로고
    • Anti-inflammatory, analgesic and antipyretic activities of the extract of gamboge from Garcinia hanburyi Hook f
    • Panthong, A., Norkaew, P., Kanjanapothi, D., et al. (2007). Anti-inflammatory, analgesic and antipyretic activities of the extract of gamboge from Garcinia hanburyi Hook f. Journal of Ethnopharmacology, 111, 335-340.
    • (2007) Journal of Ethnopharmacology , vol.111 , pp. 335-340
    • Panthong, A.1    Norkaew, P.2    Kanjanapothi, D.3
  • 11
    • 34548679604 scopus 로고    scopus 로고
    • Differential apoptotic induction of gambogic acid, a novel anticancer natural product, on hepatoma cells and normal hepatocytes
    • Yang, Y., Yang, L., You, Q. D., et al. (2007). Differential apoptotic induction of gambogic acid, a novel anticancer natural product, on hepatoma cells and normal hepatocytes. Cancer Letters, 256, 259-266.
    • (2007) Cancer Letters , vol.256 , pp. 259-266
    • Yang, Y.1    Yang, L.2    You, Q.D.3
  • 12
    • 0347320714 scopus 로고    scopus 로고
    • Discovery, characterization and SAR of gambogic acid as a potent apoptosis inducer by a HTS assay
    • Zhang, H. Z., Kasibhatla, S., Wang, Y., et al. (2004). Discovery, characterization and SAR of gambogic acid as a potent apoptosis inducer by a HTS assay. Bioorganic & Medicinal Chemistry, 12, 309-317.
    • (2004) Bioorganic & Medicinal Chemistry , vol.12 , pp. 309-317
    • Zhang, H.Z.1    Kasibhatla, S.2    Wang, Y.3
  • 13
    • 23844463880 scopus 로고    scopus 로고
    • Anticancer effect and apoptosis induction of gambogic acid in human gastric cancer line BGC-823
    • Liu, W., Guo, Q. L., You, Q. D., et al. (2005). Anticancer effect and apoptosis induction of gambogic acid in human gastric cancer line BGC-823. World Journal of Gastroenterology, 11, 3655-3659.
    • (2005) World Journal of Gastroenterology , vol.11 , pp. 3655-3659
    • Liu, W.1    Guo, Q.L.2    You, Q.D.3
  • 14
    • 55749086025 scopus 로고    scopus 로고
    • Gambogic acid mediates apoptosis as a p53 inducer through down-regulation of mdm2 in wild-type p53-expressing cancer cells
    • Gu, H., Wang, X., Rao, S., et al. (2008). Gambogic acid mediates apoptosis as a p53 inducer through down-regulation of mdm2 in wild-type p53-expressing cancer cells. Molecular Cancer Therapeutics, 7, 3298-3305.
    • (2008) Molecular Cancer Therapeutics , vol.7 , pp. 3298-3305
    • Gu, H.1    Wang, X.2    Rao, S.3
  • 15
    • 2942629656 scopus 로고    scopus 로고
    • General gambogic acids inhibited growth of human hepatoma SMMC-7721 cells in vitro and in nude mice
    • Guo, Q. L., You, Q. D., Wu, Z. Q., et al. (2004). General gambogic acids inhibited growth of human hepatoma SMMC-7721 cells in vitro and in nude mice. Acta Pharmacologica Sinica, 25, 769-774.
    • (2004) Acta Pharmacologica Sinica , vol.25 , pp. 769-774
    • Guo, Q.L.1    You, Q.D.2    Wu, Z.Q.3
  • 16
    • 35349029248 scopus 로고    scopus 로고
    • Gambogic acid, a novel ligand for transferrin receptor, potentiates TNF-induced apoptosis through modulation of the nuclear factor-kappaB signaling pathway
    • Pandey, M. K., Sung, B., Ahn, K. S., et al. (2007). Gambogic acid, a novel ligand for transferrin receptor, potentiates TNF-induced apoptosis through modulation of the nuclear factor-kappaB signaling pathway. Blood, 110, 3517-3525.
    • (2007) Blood , vol.110 , pp. 3517-3525
    • Pandey, M.K.1    Sung, B.2    Ahn, K.S.3
  • 17
    • 40949101023 scopus 로고    scopus 로고
    • Gambogic acid inhibits angiogenesis and prostate tumor growth by suppressing vascular endothelial growth factor receptor 2 signaling
    • Yi, T., Yi, Z., Cho, S. G., et al. (2008). Gambogic acid inhibits angiogenesis and prostate tumor growth by suppressing vascular endothelial growth factor receptor 2 signaling. Cancer Research, 68, 1843-1850.
    • (2008) Cancer Research , vol.68 , pp. 1843-1850
    • Yi, T.1    Yi, Z.2    Cho, S.G.3
  • 18
    • 34047133853 scopus 로고    scopus 로고
    • Gambogic acid-induced G2/M phase cell-cycle arrest via disturbing CDK7-mediated phosphorylation of CDC2/p34 in human gastric carcinoma BGC-823 cells
    • Yu, J., Guo, Q. L., You, Q. D., et al. (2007). Gambogic acid-induced G2/M phase cell-cycle arrest via disturbing CDK7-mediated phosphorylation of CDC2/p34 in human gastric carcinoma BGC-823 cells. Carcinogenesis, 28, 632-638.
    • (2007) Carcinogenesis , vol.28 , pp. 632-638
    • Yu, J.1    Guo, Q.L.2    You, Q.D.3
  • 19
    • 58149218002 scopus 로고    scopus 로고
    • Synergistic effect of 5-fluorouracil with gambogic acid on BGC-823 human gastric carcinoma
    • Wang, J., Liu, W., Zhao, Q., et al. (2009). Synergistic effect of 5-fluorouracil with gambogic acid on BGC-823 human gastric carcinoma. Toxicology, 256, 135-140.
    • (2009) Toxicology , vol.256 , pp. 135-140
    • Wang, J.1    Liu, W.2    Zhao, Q.3
  • 20
    • 84862496532 scopus 로고    scopus 로고
    • Enhancement of anticancer efficacy of chemotherapeutics by gambogic acid against gastric cancer cells
    • Zou, Z. Y., Wei, J., Li, X. L., et al. (2012). Enhancement of anticancer efficacy of chemotherapeutics by gambogic acid against gastric cancer cells. Cancer Biotherapy and Radiopharmaceuticals, 27, 299-306.
    • (2012) Cancer Biotherapy and Radiopharmaceuticals , vol.27 , pp. 299-306
    • Zou, Z.Y.1    Wei, J.2    Li, X.L.3
  • 21
    • 78651460233 scopus 로고    scopus 로고
    • Gambogic acid enhances proteasome inhibitor-induced anticancer activity
    • Huang, H., Chen, D., Li, S., et al. (2011). Gambogic acid enhances proteasome inhibitor-induced anticancer activity. Cancer Letters, 301, 221-228.
    • (2011) Cancer Letters , vol.301 , pp. 221-228
    • Huang, H.1    Chen, D.2    Li, S.3
  • 22
    • 0023019005 scopus 로고
    • Use of MTT colorimetric assay to measure cell activation
    • Gerlier, D., & Thomasset, N. (1986). Use of MTT colorimetric assay to measure cell activation. Journal of Immunological Methods, 94, 57-63.
    • (1986) Journal of Immunological Methods , vol.94 , pp. 57-63
    • Gerlier, D.1    Thomasset, N.2
  • 23
    • 77954176768 scopus 로고    scopus 로고
    • Marked anti-tumour activity of the combination of YM155, a novel survivin suppressant, and platinum-based drugs
    • Iwasa, T., Okamoto, I., Takezawa, K., et al. (2010). Marked anti-tumour activity of the combination of YM155, a novel survivin suppressant, and platinum-based drugs. British Journal of Cancer, 103, 36-42.
    • (2010) British Journal of Cancer , vol.103 , pp. 36-42
    • Iwasa, T.1    Okamoto, I.2    Takezawa, K.3
  • 24
    • 70349736107 scopus 로고    scopus 로고
    • Resveratrol suppresses growth of human ovarian cancer cells in culture and in a murine xenograft model: eukaryotic elongation factor 1A2 as a potential target
    • Lee, M. H., Choi, B. Y., Kundu, J. K., et al. (2009). Resveratrol suppresses growth of human ovarian cancer cells in culture and in a murine xenograft model: eukaryotic elongation factor 1A2 as a potential target. Cancer Research, 69, 7449-7458.
    • (2009) Cancer Research , vol.69 , pp. 7449-7458
    • Lee, M.H.1    Choi, B.Y.2    Kundu, J.K.3
  • 26
    • 80051547640 scopus 로고    scopus 로고
    • Intraperitoneal administration of novel doxorubicin loaded polymeric delivery systems against peritoneal carcinomatosis: experimental study in a murine model of ovarian cancer
    • Colombo, P. E., Boustta, M., Poujol, S., et al. (2011). Intraperitoneal administration of novel doxorubicin loaded polymeric delivery systems against peritoneal carcinomatosis: experimental study in a murine model of ovarian cancer. Gynecologic Oncology, 122, 632-640.
    • (2011) Gynecologic Oncology , vol.122 , pp. 632-640
    • Colombo, P.E.1    Boustta, M.2    Poujol, S.3
  • 27
    • 0021118703 scopus 로고
    • Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors
    • Chou, T. C., & Talalay, P. (1984). Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Advances in Enzyme Regulation, 22, 27-55.
    • (1984) Advances in Enzyme Regulation , vol.22 , pp. 27-55
    • Chou, T.C.1    Talalay, P.2
  • 28
    • 79957777942 scopus 로고    scopus 로고
    • Tetrathiomolybdate induces doxorubicin sensitivity in resistant tumor cell lines
    • Kim, K. K., Kawar, N. M., Singh, R. K., et al. (2011). Tetrathiomolybdate induces doxorubicin sensitivity in resistant tumor cell lines. Gynecologic Oncology, 122, 183-189.
    • (2011) Gynecologic Oncology , vol.122 , pp. 183-189
    • Kim, K.K.1    Kawar, N.M.2    Singh, R.K.3
  • 29
    • 67349089550 scopus 로고    scopus 로고
    • Reactive oxygen species accumulation contributes to gambogic acid-induced apoptosis in human hepatoma SMMC-7721 cells
    • Nie, F., Zhang, X., Qi, Q., et al. (2009). Reactive oxygen species accumulation contributes to gambogic acid-induced apoptosis in human hepatoma SMMC-7721 cells. Toxicology, 260, 60-67.
    • (2009) Toxicology , vol.260 , pp. 60-67
    • Nie, F.1    Zhang, X.2    Qi, Q.3
  • 30
    • 33646394582 scopus 로고    scopus 로고
    • Doxorubicin-DNA adducts induce a non-topoisomerase II-mediated form of cell death
    • Swift, L. P., Rephaeli, A., Nudelman, A., et al. (2006). Doxorubicin-DNA adducts induce a non-topoisomerase II-mediated form of cell death. Cancer Research, 66, 4863-4871.
    • (2006) Cancer Research , vol.66 , pp. 4863-4871
    • Swift, L.P.1    Rephaeli, A.2    Nudelman, A.3
  • 31
    • 0033006172 scopus 로고    scopus 로고
    • A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin
    • Gewirtz, D. A. (1999). A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin. Biochemical Pharmacology, 57, 727-741.
    • (1999) Biochemical Pharmacology , vol.57 , pp. 727-741
    • Gewirtz, D.A.1
  • 32
    • 4544295035 scopus 로고    scopus 로고
    • Fenretinide induces sustained-activation of JNK/p38 MAPK and apoptosis in a reactive oxygen species-dependent manner in neuroblastoma cells
    • Osone, S., Hosoi, H., Kuwahara, Y., et al. (2004). Fenretinide induces sustained-activation of JNK/p38 MAPK and apoptosis in a reactive oxygen species-dependent manner in neuroblastoma cells. International Journal of Cancer, 112, 219-224.
    • (2004) International Journal of Cancer , vol.112 , pp. 219-224
    • Osone, S.1    Hosoi, H.2    Kuwahara, Y.3
  • 33
    • 0038482086 scopus 로고    scopus 로고
    • Sustained activation of JNK/p38 MAPK pathways in response to cisplatin leads to Fas ligand induction and cell death in ovarian carcinoma cells
    • Mansouri, A., Ridgway, L. D., Korapati, A. L., et al. (2003). Sustained activation of JNK/p38 MAPK pathways in response to cisplatin leads to Fas ligand induction and cell death in ovarian carcinoma cells. Journal of Biological Chemistry, 278, 19245-19256.
    • (2003) Journal of Biological Chemistry , vol.278 , pp. 19245-19256
    • Mansouri, A.1    Ridgway, L.D.2    Korapati, A.L.3
  • 34
    • 79961139784 scopus 로고    scopus 로고
    • Management strategies for recurrent platinum-resistant ovarian cancer
    • Naumann, R. W., & Coleman, R. L. (2011). Management strategies for recurrent platinum-resistant ovarian cancer. Drugs, 71, 1397-1412.
    • (2011) Drugs , vol.71 , pp. 1397-1412
    • Naumann, R.W.1    Coleman, R.L.2
  • 35
    • 48049101768 scopus 로고    scopus 로고
    • Phase I human tolerability trial of gambogic acid
    • Wang, J., & Zhou, Z. (2007). Phase I human tolerability trial of gambogic acid. Chinese Journal of New Drugs, 16, 79-82.
    • (2007) Chinese Journal of New Drugs , vol.16 , pp. 79-82
    • Wang, J.1    Zhou, Z.2
  • 36
    • 70349773507 scopus 로고    scopus 로고
    • Gambogic acid reduced bcl-2 expression via p53 in human breast MCF-7 cancer cells
    • Gu, H., Rao, S., Zhao, J., et al. (2009). Gambogic acid reduced bcl-2 expression via p53 in human breast MCF-7 cancer cells. Journal of Cancer Research and Clinical Oncology, 135, 1777-1782.
    • (2009) Journal of Cancer Research and Clinical Oncology , vol.135 , pp. 1777-1782
    • Gu, H.1    Rao, S.2    Zhao, J.3
  • 37
    • 9644266405 scopus 로고    scopus 로고
    • Gambogic acid induces apoptosis and regulates expressions of Bax and Bcl-2 protein in human gastric carcinoma MGC-803 cells
    • Zhao, L., Guo, Q. L., You, Q. D., et al. (2004). Gambogic acid induces apoptosis and regulates expressions of Bax and Bcl-2 protein in human gastric carcinoma MGC-803 cells. Biological & Pharmaceutical Bulletin, 27, 998-1003.
    • (2004) Biological & Pharmaceutical Bulletin , vol.27 , pp. 998-1003
    • Zhao, L.1    Guo, Q.L.2    You, Q.D.3
  • 38
    • 59149095869 scopus 로고    scopus 로고
    • Gambogic acid induces apoptosis by regulating the expression of Bax and Bcl-2 and enhancing caspase-3 activity in human malignant melanoma A375 cells
    • Xu, X., Liu, Y., Wang, L., et al. (2009). Gambogic acid induces apoptosis by regulating the expression of Bax and Bcl-2 and enhancing caspase-3 activity in human malignant melanoma A375 cells. International Journal of Dermatology, 48, 186-192.
    • (2009) International Journal of Dermatology , vol.48 , pp. 186-192
    • Xu, X.1    Liu, Y.2    Wang, L.3
  • 39
    • 77954761399 scopus 로고    scopus 로고
    • Gambogic acid triggers DNA damage signaling that induces p53/p21(Waf1/CIP1) activation through the ATR-Chk1 pathway
    • Rong, J. J., Hu, R., Song, X. M., et al. (2010). Gambogic acid triggers DNA damage signaling that induces p53/p21(Waf1/CIP1) activation through the ATR-Chk1 pathway. Cancer Letters, 296, 55-64.
    • (2010) Cancer Letters , vol.296 , pp. 55-64
    • Rong, J.J.1    Hu, R.2    Song, X.M.3
  • 40
    • 40849094400 scopus 로고    scopus 로고
    • Gambogic acid, a potent inhibitor of survivin, reverses docetaxel resistance in gastric cancer cells
    • Wang, T., Wei, J., Qian, X., et al. (2008). Gambogic acid, a potent inhibitor of survivin, reverses docetaxel resistance in gastric cancer cells. Cancer Letters, 262, 214-222.
    • (2008) Cancer Letters , vol.262 , pp. 214-222
    • Wang, T.1    Wei, J.2    Qian, X.3
  • 41
    • 46449099079 scopus 로고    scopus 로고
    • Microtubule depolymerization and phosphorylation of c-Jun N-terminal kinase-1 and p38 were involved in gambogic acid induced cell cycle arrest and apoptosis in human breast carcinoma MCF-7 cells
    • Chen, J., Gu, H. Y., Lu, N., et al. (2008). Microtubule depolymerization and phosphorylation of c-Jun N-terminal kinase-1 and p38 were involved in gambogic acid induced cell cycle arrest and apoptosis in human breast carcinoma MCF-7 cells. Life Sciences, 83, 103-109.
    • (2008) Life Sciences , vol.83 , pp. 103-109
    • Chen, J.1    Gu, H.Y.2    Lu, N.3
  • 42
    • 67649995348 scopus 로고    scopus 로고
    • Gambogic acid induces G0/G1 arrest and apoptosis involving inhibition of SRC-3 and inactivation of Akt pathway in K562 leukemia cells
    • Li, R., Chen, Y., Zeng, L. L., et al. (2009). Gambogic acid induces G0/G1 arrest and apoptosis involving inhibition of SRC-3 and inactivation of Akt pathway in K562 leukemia cells. Toxicology, 262, 98-105.
    • (2009) Toxicology , vol.262 , pp. 98-105
    • Li, R.1    Chen, Y.2    Zeng, L.L.3
  • 44
    • 67650071137 scopus 로고    scopus 로고
    • Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
    • Trachootham, D., Alexandre, J., & Huang, P. (2009). Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? Nature Reviews Drug Discovery, 8, 579-591.
    • (2009) Nature Reviews Drug Discovery , vol.8 , pp. 579-591
    • Trachootham, D.1    Alexandre, J.2    Huang, P.3
  • 45
    • 0024352416 scopus 로고
    • Adriamycin activation and oxygen free radical formation in human breast tumor cells: protective role of glutathione peroxidase in adriamycin resistance
    • Sinha, B. K., Mimnaugh, E. G., Rajagopalan, S., & Myers, C. E. (1989). Adriamycin activation and oxygen free radical formation in human breast tumor cells: protective role of glutathione peroxidase in adriamycin resistance. Cancer Research, 49, 3844-3848.
    • (1989) Cancer Research , vol.49 , pp. 3844-3848
    • Sinha, B.K.1    Mimnaugh, E.G.2    Rajagopalan, S.3    Myers, C.E.4
  • 47
    • 84863595623 scopus 로고    scopus 로고
    • Melatonin potentiates chemotherapy-induced cytotoxicity and apoptosis in rat pancreatic tumor cells
    • Uguz, A. C., Cig, B., Espino, J., et al. (2012). Melatonin potentiates chemotherapy-induced cytotoxicity and apoptosis in rat pancreatic tumor cells. Journal of Pineal Research, 53, 91-98.
    • (2012) Journal of Pineal Research , vol.53 , pp. 91-98
    • Uguz, A.C.1    Cig, B.2    Espino, J.3
  • 48
    • 78149278340 scopus 로고    scopus 로고
    • Sildenafil increases chemotherapeutic efficacy of doxorubicin in prostate cancer and ameliorates cardiac dysfunction
    • Das, A., Durrant, D., Mitchell, C., et al. (2010). Sildenafil increases chemotherapeutic efficacy of doxorubicin in prostate cancer and ameliorates cardiac dysfunction. Proceedings of the National Academy of Sciences USA, 107, 18202-18207.
    • (2010) Proceedings of the National Academy of Sciences USA , vol.107 , pp. 18202-18207
    • Das, A.1    Durrant, D.2    Mitchell, C.3
  • 49
    • 0032080283 scopus 로고    scopus 로고
    • Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1
    • Saitoh, M., Nishitoh, H., Fujii, M., et al. (1998). Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO Journal, 17, 2596-2606.
    • (1998) EMBO Journal , vol.17 , pp. 2596-2606
    • Saitoh, M.1    Nishitoh, H.2    Fujii, M.3
  • 50
    • 33747081043 scopus 로고    scopus 로고
    • Toxicological studies of gambogic acid and its potential targets in experimental animals
    • Guo, Q., Qi, Q., You, Q., et al. (2006). Toxicological studies of gambogic acid and its potential targets in experimental animals. Basic & Clinical Pharmacology & Toxicology, 99, 178-184.
    • (2006) Basic & Clinical Pharmacology & Toxicology , vol.99 , pp. 178-184
    • Guo, Q.1    Qi, Q.2    You, Q.3


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