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Volumn 45, Issue 9, 2010, Pages 4343-4353

Studies on chemical modification and biology of a natural product, gambogic acid (II): Synthesis and bioevaluation of gambogellic acid and its derivatives from gambogic acid as antitumor agents

(7) Wang, Jinxin a Ma, Junhai a You, Qidong a Zhao, Li a Wang, Fan a Li, Chong a Guo, Qinglong a

a CHINA PHARMACEUTICAL UNIVERSITY (China)

Author keywords

Antitumor activity; Apoptosis; Gambogellic acid; Gambogic acid; Oxygenation

Indexed keywords

(32,33) EPOXY 40 METHYL GAMBOGELLIC ACID 30 CARBOXYLIC METHYL ESTER 37 ENE; (38,40) EPOXY 33 CHLOROGAMBOGELLIC ACID; (38,40) EPOXY GAMBOGELLIC ACID 30 CARBOXYLIC METHYL ESTER; (9,10) DIHYDROXYL 33 CHLOROGAMBOGELLIC ACID; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 33 CHLOROGAMBOGELLIC ACID; 33 CHLOROGAMBOGELLIC ACID 30 CARBOXYLIC METHYL ESTER; 34 HYDROXYMETHYL GAMBOGELLIC ACID 30 CARBOXYLIC METHYL ESTER; 36 KETONE (38,40) DI HYDROGEN 33 CHLOROGAMBOGELLIC ACID; 4.1.1034 HYDROXYMETHYL GAMBOGELLIC ACID 30 CARBOXYLIC METHYL ESTER 37 ENE; 40 METHYL GAMBOGELLIC ACID 30 CARBOXYLIC METHYL ESTER 37 ENE; 40 METHYL GAMBOGELLIC ACID 37 ENE 6 AND GAMBOGELLIC ACID; ANNEXIN; ANTINEOPLASTIC AGENT; GAMBOGELLIC ACID 30 CARBOXYLIC METHYL ESTER; GAMBOGIC ACID; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL ASSAY; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MORPHOLOGY; OBSERVATION; STRUCTURE ACTIVITY RELATION;

ANNEXIN A5; ANTINEOPLASTIC AGENTS; APOPTOSIS; BIOLOGICAL PRODUCTS; CELL LINE, TUMOR; HUMANS; INHIBITORY CONCENTRATION 50; STRUCTURE-ACTIVITY RELATIONSHIP; XANTHONES;

EID: 77955549408 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2010.04.037 Document Type: Article

Times cited : (29)

References (31)

1
- 77955550924
- Jiangxi Med
- The Cooperation of Gambogia Anticancer Investigation vol. 3 1982 Jiangxi Med pp. 1-6
- (1982) The Cooperation of Gambogia Anticancer Investigation , vol.3

2
- 31844445117
- H. Auterhoff, H. Frauendorf, W. Liesenklas, and C. Schwandt Arch. Pharm. 295 1962 833 846
- (1962) Arch. Pharm. , vol.295 , pp. 833-846
- Auterhoff, H.¹ Frauendorf, H.² Liesenklas, W.³ Schwandt, C.⁴

3
- 84989029929
- L.J. Lin, L.Z. Lin, J.M. Pezzuto, and G.A. Cordell Magn. Reson. Chem. 31 1993 340 348
- (1993) Magn. Reson. Chem. , vol.31 , pp. 340-348
- Lin, L.J.¹ Lin, L.Z.² Pezzuto, J.M.³ Cordell, G.A.⁴

4
- 0030087854
- J. Asano, K. Chiba, M. Tada, and T. Yoshii Phytochemistry 41 1996 815 820
- (1996) Phytochemistry , vol.41 , pp. 815-820
- Asano, J.¹ Chiba, K.² Tada, M.³ Yoshii, T.⁴

5
- 85066230955
- W. Liesenklas, and H. Auterhoff Arch. Pharm. Ber. Dtsch. Pharm. Ges. 299 1966 97
- (1966) Arch. Pharm. Ber. Dtsch. Pharm. Ges. , vol.299 , pp. 97
- Liesenklas, W.¹ Auterhoff, H.²

6
- 9644266405
- L. Zhao, Q.L. Guo, Q.D. You, Z.Q. Wu, and H.Y. Gu Biol. Pharm. Bull. 27 2004 998 1003
- (2004) Biol. Pharm. Bull. , vol.27 , pp. 998-1003
- Zhao, L.¹ Guo, Q.L.² You, Q.D.³ Wu, Z.Q.⁴ Gu, H.Y.⁵

7
- 23844463880
- W. Liu, Q.L. Guo, Q.D. You, L. Zhao, H.Y. Gu, and S.T. Yuan World J. Gastroenterol. 11 2005 3655 3659
- (2005) World J. Gastroenterol. , vol.11 , pp. 3655-3659
- Liu, W.¹ Guo, Q.L.² You, Q.D.³ Zhao, L.⁴ Gu, H.Y.⁵ Yuan, S.T.⁶

8
- 20344405555
- Z.Q. Wu, Q.L. Guo, Q.D. You, L. Zhao, and H.Y. Gu Biol. Pharm. Bull. 27 2004 1769 1774
- (2004) Biol. Pharm. Bull. , vol.27 , pp. 1769-1774
- Wu, Z.Q.¹ Guo, Q.L.² You, Q.D.³ Zhao, L.⁴ Gu, H.Y.⁵

9
- 2942629656
- Q.L. Guo, Q.D. You, Z.Q. Wu, S.T. Yuan, and L. Zhao Acta Pharmacol. Sin. 25 2004 769 773
- (2004) Acta Pharmacol. Sin. , vol.25 , pp. 769-773
- Guo, Q.L.¹ You, Q.D.² Wu, Z.Q.³ Yuan, S.T.⁴ Zhao, L.⁵

10
- 24744435348
- S. Kasibhatla, K.A. Jessen, S. Maliartchouk, J.Y. Wang, N.M. English, J. Drewe, L. Qiu, S.P. Archer, A.E. Ponce, N. Sirisoma, S.C. Jiang, H.Z. Zhang, K.R. Gehlsen, S.X. Cai, D.R. Green, and B. Tseng Proc. Natl. Acad. Sci. U.S.A. 102 2005 12095 12100
- (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 12095-12100
- Kasibhatla, S.¹ Jessen, K.A.² Maliartchouk, S.³ Wang, J.Y.⁴ English, N.M.⁵ Drewe, J.⁶ Qiu, L.⁷ Archer, S.P.⁸ Ponce, A.E.⁹ Sirisoma, N.¹⁰ Jiang, S.C.¹¹ Zhang, H.Z.¹² Gehlsen, K.R.¹³ Cai, S.X.¹⁴ Green, D.R.¹⁵ Tseng, B.¹⁶

11
- 35349029248
- M.K. Pandey, B. Sung, K.S. Ahn, A.B. Kunnumakkara, M.M. Chaturvedi, and B.B. Aggarwal Blood 110 2007 3517 3525
- (2007) Blood , vol.110 , pp. 3517-3525
- Pandey, M.K.¹ Sung, B.² Ahn, K.S.³ Kunnumakkara, A.B.⁴ Chaturvedi, M.M.⁵ Aggarwal, B.B.⁶

12
- 58249123414
- E. Ortiz-Sánchez1, T.R. Daniels, G. Helguera, O. Martinez-Maza, B. Bonavida, and M.L. Peniche Leukemia 23 2009 59 62
- (2009) Leukemia , vol.23 , pp. 59-62
- Ortiz-Sánchezl, E.¹ Daniels, T.R.² Helguera, G.³ Martinez-Maza, O.⁴ Bonavida, B.⁵ Peniche, M.L.⁶

13
- 34047133853
- J. Yu, Q.L. Guo, and Q.D. You Carcinogenesis 28 2007 632 638
- (2007) Carcinogenesis , vol.28 , pp. 632-638
- Yu, J.¹ Guo, Q.L.² You, Q.D.³

14
- 31844434032
- Q.L. Guo, S.S. Lin, and Q.D. You Life Sci. 78 2006 1238 1245
- (2006) Life Sci. , vol.78 , pp. 1238-1245
- Guo, Q.L.¹ Lin, S.S.² You, Q.D.³

15
- 33745698235
- J. Yu, Q.L. Guo, and Q.D. You Cancer Chemother. Pharmacol. 58 2006 434 443
- (2006) Cancer Chemother. Pharmacol. , vol.58 , pp. 434-443
- Yu, J.¹ Guo, Q.L.² You, Q.D.³

16
- 35348952483
- N. Lu, Y. Yang, Q.D. You, Y. Ling, Y. Gao, H.Y. Gu, L. Zhao, X.T. Wang, and Q.L. Guo Cancer Lett. 258 2007 80 89
- (2007) Cancer Lett. , vol.258 , pp. 80-89
- Lu, N.¹ Yang, Y.² You, Q.D.³ Ling, Y.⁴ Gao, Y.⁵ Gu, H.Y.⁶ Zhao, L.⁷ Wang, X.T.⁸ Guo, Q.L.⁹

17
- 34548679604
- Y. Yang, L. Yang, Q.D. You, F.F. Nie, H.Y. Gu, L. Zhao, X.T. Wang, and Q.L. Guo Cancer Lett. 256 2007 259 266
- (2007) Cancer Lett. , vol.256 , pp. 259-266
- Yang, Y.¹ Yang, L.² You, Q.D.³ Nie, F.F.⁴ Gu, H.Y.⁵ Zhao, L.⁶ Wang, X.T.⁷ Guo, Q.L.⁸

18
- 51749101694
- H.Y. Gu, Q.D. You, W. Liu, Y. Yang, L. Zhao, Q. Qi, J. Zhao, J. Wang, N. Lu, H. Ling, Q.L. Guo, and X.T. Wang Int. Immunopharmacol. 8 2008 1493 1497
- (2008) Int. Immunopharmacol. , vol.8 , pp. 1493-1497
- Gu, H.Y.¹ You, Q.D.² Liu, W.³ Yang, Y.⁴ Zhao, L.⁵ Qi, Q.⁶ Zhao, J.⁷ Wang, J.⁸ Lu, N.⁹ Ling, H.¹⁰ Guo, Q.L.¹¹ Wang, X.T.¹²

19
- 46449099079
- J. Chen, H.Y. Gu, N. Lu, Y. Yang, W. Liu, Q. Qi, J.J. Rong, X.T. Wang, Q.D. You, and Q.L. Guo Life Sci. 83 (2008 103
- (2008) Life Sci. , vol.83 , pp. 103
- Chen, J.¹ Gu, H.Y.² Lu, N.³ Yang, Y.⁴ Liu, W.⁵ Qi, Q.⁶ Rong, J.J.⁷ Wang, X.T.⁸ You, Q.D.⁹ Guo, Q.L.¹⁰

20
- 56949096780
- Q. Qi, H.Y. Gu, Y. Yang, N. Lu, J. Zhao, W. Liu, H. Ling, Q.D. You, X.T. Wang, and Q.L. Guo J. Mol. Med. 86 2008 1367 1377
- (2008) J. Mol. Med. , vol.86 , pp. 1367-1377
- Qi, Q.¹ Gu, H.Y.² Yang, Y.³ Lu, N.⁴ Zhao, J.⁵ Liu, W.⁶ Ling, H.⁷ You, Q.D.⁸ Wang, X.T.⁹ Guo, Q.L.¹⁰

21
- 55749086025
- H.Y. Gu, X.T. Wang, S.Y. Rao, J. Wang, J. Zhao, F.L. Ren, R. Mu, Y. Yang, Q. Qi, W. Liu, N. Lu, H. Ling, Q.D. You, and Q.L. Guo Mol Cancer Ther. 7 2008 3298 3346
- (2008) Mol Cancer Ther. , vol.7 , pp. 3298-3346
- Gu, H.Y.¹ Wang, X.T.² Rao, S.Y.³ Wang, J.⁴ Zhao, J.⁵ Ren, F.L.⁶ Mu, R.⁷ Yang, Y.⁸ Qi, Q.⁹ Liu, W.¹⁰ Lu, N.¹¹ Ling, H.¹² You, Q.D.¹³ Guo, Q.L.¹⁴

22
- 64249157689
- J.X. Wang, L. Zhao, Y. Hu, Q.L. Guo, L. Zhang, X.J. Wang, N.G. Li, and Q.D. You Eur. J. Med. Chem. 44 2009 2611 2620
- (2009) Eur. J. Med. Chem. , vol.44 , pp. 2611-2620
- Wang, J.X.¹ Zhao, L.² Hu, Y.³ Guo, Q.L.⁴ Zhang, L.⁵ Wang, X.J.⁶ Li, N.G.⁷ You, Q.D.⁸

23
- 0001052053
- W.I. Ollis, M.V.J. Ramsay, and I.O. Sutherland Tetrahedron 21 1965 1453 1460
- (1965) Tetrahedron , vol.21 , pp. 1453-1460
- Ollis, W.I.¹ Ramsay, M.V.J.² Sutherland, I.O.³

24
- 23144431568
- F. Feng, W.Y. Liu, Y.S. Chen, Q.L. Guo, and Q.D. You J. Chin. Pharma. Uni. 36 2005 302 305
- (2005) J. Chin. Pharma. Uni. , vol.36 , pp. 302-305
- Feng, F.¹ Liu, W.Y.² Chen, Y.S.³ Guo, Q.L.⁴ You, Q.D.⁵

25
- 0015878639
- D. Brewster, M. Myers, and P. Ormerod J. Chem. Soc. Perkin Trans I. 1973 2796 2801
- (1973) J. Chem. Soc. Perkin Trans I. , pp. 2796-2801
- Brewster, D.¹ Myers, M.² Ormerod, P.³

26
- 33947293504
- U.T. Bhalerao, and H. Rapoport J. Am. Chem. Soc. 93 1971 4835 4840
- (1971) J. Am. Chem. Soc. , vol.93 , pp. 4835-4840
- Bhalerao, U.T.¹ Rapoport, H.²

27
- 0025030673
- J.E. McMurry, and R.G. Dushin J. Am. Chem. Soc. 112 1990 6942 6947
- (1990) J. Am. Chem. Soc. , vol.112 , pp. 6942-6947
- McMurry, J.E.¹ Dushin, R.G.²

28
- 0001386463
- N.K.N. Yee, and R.M. Coates J. Org. Chem. 57 1992 4598 4603
- (1992) J. Org. Chem. , vol.57 , pp. 4598-4603
- Yee, N.K.N.¹ Coates, R.M.²

29
- 0347320714
- H.Z. Zhang, S. Kasibhatla, Y. Wang, J. Herich, J. Guastella, B. Tseng, J. Drewe, and S.X. Cai Bioorg. Med. Chem. 12 2004 309 317
- (2004) Bioorg. Med. Chem. , vol.12 , pp. 309-317
- Zhang, H.Z.¹ Kasibhatla, S.² Wang, Y.³ Herich, J.⁴ Guastella, J.⁵ Tseng, B.⁶ Drewe, J.⁷ Cai, S.X.⁸

30
- 2942519394
- Q.L. Guo, L. Zhao, and Q.D. You Chin. J. Nat. Med. 2 2004 106 110
- (2004) Chin. J. Nat. Med. , vol.2 , pp. 106-110
- Guo, Q.L.¹ Zhao, L.² You, Q.D.³

31
- 64249117068
- M.F. Florian, A.J. Claude, and A. Markus Appl. Environ. Microbiol. 65 1999 3727 3729
- (1999) Appl. Environ. Microbiol. , vol.65 , pp. 3727-3729
- Florian, M.F.¹ Claude, A.J.² Markus, A.³

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