-
1
-
-
0142059890
-
Molecular mechanism for a role of SHP2 in epidermal growth factor receptor signaling
-
Agazie Y.M., Hayman M.J. Molecular mechanism for a role of SHP2 in epidermal growth factor receptor signaling. Mol Cell Biol 2003, 23:7875-7886.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 7875-7886
-
-
Agazie, Y.M.1
Hayman, M.J.2
-
2
-
-
0025201012
-
The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins
-
Ballester R., Marchuk D., Boguski M., Saulino A., Letcher R., Wigler M., et al. The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins. Cell 1990, 63:851-859.
-
(1990)
Cell
, vol.63
, pp. 851-859
-
-
Ballester, R.1
Marchuk, D.2
Boguski, M.3
Saulino, A.4
Letcher, R.5
Wigler, M.6
-
3
-
-
84859169877
-
The cancer cell line encyclopedia enables predictive modelling of anticancer drug sensitivity
-
Barretina J., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., et al. The cancer cell line encyclopedia enables predictive modelling of anticancer drug sensitivity. Nature 2012, 483:603-607.
-
(2012)
Nature
, vol.483
, pp. 603-607
-
-
Barretina, J.1
Caponigro, G.2
Stransky, N.3
Venkatesan, K.4
Margolin, A.A.5
Kim, S.6
-
4
-
-
0026521070
-
Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients
-
Basu T.N., Gutmann D.H., Fletcher J.A., Glover T.W., Collins F.S., Downward J. Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients. Nature 1992, 356:713-715.
-
(1992)
Nature
, vol.356
, pp. 713-715
-
-
Basu, T.N.1
Gutmann, D.H.2
Fletcher, J.A.3
Glover, T.W.4
Collins, F.S.5
Downward, J.6
-
5
-
-
84894113785
-
Acquired resistance to dasatinib in lung Cancer cell lines conferred by DDR2 gatekeeper mutation and NF1 loss
-
Beauchamp E.M., Woods B.A., Dulak A.M., Tan L., Xu C., Gray N.S., et al. Acquired resistance to dasatinib in lung Cancer cell lines conferred by DDR2 gatekeeper mutation and NF1 loss. Mol Cancer Ther 2014, 13:475-482.
-
(2014)
Mol Cancer Ther
, vol.13
, pp. 475-482
-
-
Beauchamp, E.M.1
Woods, B.A.2
Dulak, A.M.3
Tan, L.4
Xu, C.5
Gray, N.S.6
-
6
-
-
10844295905
-
Androgen-induced differentiation and tumorigenicity of human prostate epithelial cells
-
Berger R., Febbo P.G., Majumder P.K., Zhao J.J., Mukherjee S., Signoretti S., et al. Androgen-induced differentiation and tumorigenicity of human prostate epithelial cells. Cancer Res 2004, 64:8867-8875.
-
(2004)
Cancer Res
, vol.64
, pp. 8867-8875
-
-
Berger, R.1
Febbo, P.G.2
Majumder, P.K.3
Zhao, J.J.4
Mukherjee, S.5
Signoretti, S.6
-
7
-
-
0037451803
-
GAPs galore! A survey of putative Ras superfamily GTPase activating proteins in man and Drosophila
-
Bernards A. GAPs galore! A survey of putative Ras superfamily GTPase activating proteins in man and Drosophila. Biochim Biophys Acta 2003, 1603:47-82.
-
(2003)
Biochim Biophys Acta
, vol.1603
, pp. 47-82
-
-
Bernards, A.1
-
8
-
-
3042796979
-
GAP control: regulating the regulators of small GTPases
-
Bernards A., Settleman J. GAP control: regulating the regulators of small GTPases. Trends Cell Biol 2004, 14:377-385.
-
(2004)
Trends Cell Biol
, vol.14
, pp. 377-385
-
-
Bernards, A.1
Settleman, J.2
-
9
-
-
24944582633
-
GAPs in growth factor signalling
-
Bernards A., Settleman J. GAPs in growth factor signalling. Growth Factors 2005, 23:143-149.
-
(2005)
Growth Factors
, vol.23
, pp. 143-149
-
-
Bernards, A.1
Settleman, J.2
-
10
-
-
34249018367
-
GEFs and GAPs: critical elements in the control of small G proteins
-
Bos J.L., Rehmann H., Wittinghofer A. GEFs and GAPs: critical elements in the control of small G proteins. Cell 2007, 129:865-877.
-
(2007)
Cell
, vol.129
, pp. 865-877
-
-
Bos, J.L.1
Rehmann, H.2
Wittinghofer, A.3
-
11
-
-
84875586467
-
Neurofibromatosis-1 gene deletions and mutations in de novo adult acute myeloid leukemia
-
Boudry-Labis E., Roche-Lestienne C., Nibourel O., Boissel N., Terre C., Perot C., et al. Neurofibromatosis-1 gene deletions and mutations in de novo adult acute myeloid leukemia. Am J Hematol 2013, 88:306-311.
-
(2013)
Am J Hematol
, vol.88
, pp. 306-311
-
-
Boudry-Labis, E.1
Roche-Lestienne, C.2
Nibourel, O.3
Boissel, N.4
Terre, C.5
Perot, C.6
-
12
-
-
15744404625
-
Hyaluronan-CD44 interaction with IQGAP1 promotes Cdc42 and ERK signaling, leading to actin binding, Elk-1/estrogen receptor transcriptional activation, and ovarian cancer progression
-
Bourguignon L.Y., Gilad E., Rothman K., Peyrollier K. Hyaluronan-CD44 interaction with IQGAP1 promotes Cdc42 and ERK signaling, leading to actin binding, Elk-1/estrogen receptor transcriptional activation, and ovarian cancer progression. JBiol Chem 2005, 280:11961-11972.
-
(2005)
JBiol Chem
, vol.280
, pp. 11961-11972
-
-
Bourguignon, L.Y.1
Gilad, E.2
Rothman, K.3
Peyrollier, K.4
-
13
-
-
34548328245
-
Germline loss-of-function mutations in SPRED1 cause a neurofibromatosis 1-like phenotype
-
Brems H., Chmara M., Sahbatou M., Denayer E., Taniguchi K., Kato R., et al. Germline loss-of-function mutations in SPRED1 cause a neurofibromatosis 1-like phenotype. Nat Genet 2007, 39:1120-1126.
-
(2007)
Nat Genet
, vol.39
, pp. 1120-1126
-
-
Brems, H.1
Chmara, M.2
Sahbatou, M.3
Denayer, E.4
Taniguchi, K.5
Kato, R.6
-
14
-
-
0029784514
-
The Ras GTPase-activating-protein-related human protein IQGAP2 harbors a potential actin binding domain and interacts with calmodulin and Rho family GTPases
-
Brill S., Li S., Lyman C.W., Church D.M., Wasmuth J.J., Weissbach L., et al. The Ras GTPase-activating-protein-related human protein IQGAP2 harbors a potential actin binding domain and interacts with calmodulin and Rho family GTPases. Mol Cell Biol 1996, 16:4869-4878.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 4869-4878
-
-
Brill, S.1
Li, S.2
Lyman, C.W.3
Church, D.M.4
Wasmuth, J.J.5
Weissbach, L.6
-
15
-
-
84873844410
-
Sustained MEK inhibition abrogates myeloproliferative disease in Nf1 mutant mice
-
Chang T., Krisman K., Theobald E.H., Xu J., Akutagawa J., Lauchle J.O., et al. Sustained MEK inhibition abrogates myeloproliferative disease in Nf1 mutant mice. JClin Invest 2013, 123:335-339.
-
(2013)
JClin Invest
, vol.123
, pp. 335-339
-
-
Chang, T.1
Krisman, K.2
Theobald, E.H.3
Xu, J.4
Akutagawa, J.5
Lauchle, J.O.6
-
16
-
-
20444475352
-
Down-regulation of human DAB2IP gene expression mediated by polycomb Ezh2 complex and histone deacetylase in prostate cancer
-
Chen H., Tu S.W., Hsieh J.T. Down-regulation of human DAB2IP gene expression mediated by polycomb Ezh2 complex and histone deacetylase in prostate cancer. JBiol Chem 2005, 280:22437-22444.
-
(2005)
JBiol Chem
, vol.280
, pp. 22437-22444
-
-
Chen, H.1
Tu, S.W.2
Hsieh, J.T.3
-
17
-
-
85028113437
-
Translating p53 into the clinic
-
Cheok C.F., Verma C.S., Baselga J., Lane D.P. Translating p53 into the clinic. Nat Rev Clin Oncol 2011, 8:25-37.
-
(2011)
Nat Rev Clin Oncol
, vol.8
, pp. 25-37
-
-
Cheok, C.F.1
Verma, C.S.2
Baselga, J.3
Lane, D.P.4
-
18
-
-
0035936783
-
NF1 tumor suppressor gene function: narrowing the GAP
-
Cichowski K., Jacks T. NF1 tumor suppressor gene function: narrowing the GAP. Cell 2001, 104:593-604.
-
(2001)
Cell
, vol.104
, pp. 593-604
-
-
Cichowski, K.1
Jacks, T.2
-
19
-
-
0037443055
-
Dynamic regulation of the Ras pathway via proteolysis of the NF1 tumor suppressor
-
Cichowski K., Santiago S., Jardim M., Johnson B.W., Jacks T. Dynamic regulation of the Ras pathway via proteolysis of the NF1 tumor suppressor. Genes Dev 2003, 17:449-454.
-
(2003)
Genes Dev
, vol.17
, pp. 449-454
-
-
Cichowski, K.1
Santiago, S.2
Jardim, M.3
Johnson, B.W.4
Jacks, T.5
-
20
-
-
0032763861
-
Mouse models of tumor development in neurofibromatosis type 1
-
Cichowski K., Shih T.S., Schmitt E., Santiago S., Reilly K., McLaughlin M.E., et al. Mouse models of tumor development in neurofibromatosis type 1. Science 1999, 286:2172-2176.
-
(1999)
Science
, vol.286
, pp. 2172-2176
-
-
Cichowski, K.1
Shih, T.S.2
Schmitt, E.3
Santiago, S.4
Reilly, K.5
McLaughlin, M.E.6
-
21
-
-
0027456990
-
Invivo binding properties of SH2 domains from GTPase-activating protein and phosphatidylinositol 3-kinase
-
Cooper J.A., Kashishian A. Invivo binding properties of SH2 domains from GTPase-activating protein and phosphatidylinositol 3-kinase. Mol Cell Biol 1993, 13:1737-1745.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 1737-1745
-
-
Cooper, J.A.1
Kashishian, A.2
-
22
-
-
33845292259
-
Anegative feedback signaling network underlies oncogene-induced senescence
-
Courtois-Cox S., Genther Williams S.M., Reczek E.E., Johnson B.W., McGillicuddy L.T., Johannessen C.M., et al. Anegative feedback signaling network underlies oncogene-induced senescence. Cancer Cell 2006, 10:459-472.
-
(2006)
Cancer Cell
, vol.10
, pp. 459-472
-
-
Courtois-Cox, S.1
Genther Williams, S.M.2
Reczek, E.E.3
Johnson, B.W.4
McGillicuddy, L.T.5
Johannessen, C.M.6
-
23
-
-
33645831773
-
Anovel bipartite phospholipid-binding module in the neurofibromatosis type 1 protein
-
D'Angelo I., Welti S., Bonneau F., Scheffzek K. Anovel bipartite phospholipid-binding module in the neurofibromatosis type 1 protein. EMBO Rep 2006, 7:174-179.
-
(2006)
EMBO Rep
, vol.7
, pp. 174-179
-
-
D'Angelo, I.1
Welti, S.2
Bonneau, F.3
Scheffzek, K.4
-
24
-
-
16844375160
-
Proteomic analysis reveals hyperactivation of the mammalian target of rapamycin pathway in neurofibromatosis 1-associated human and mouse brain tumors
-
Dasgupta B., Yi Y., Chen D.Y., Weber J.D., Gutmann D.H. Proteomic analysis reveals hyperactivation of the mammalian target of rapamycin pathway in neurofibromatosis 1-associated human and mouse brain tumors. Cancer Res 2005, 65:2755-2760.
-
(2005)
Cancer Res
, vol.65
, pp. 2755-2760
-
-
Dasgupta, B.1
Yi, Y.2
Chen, D.Y.3
Weber, J.D.4
Gutmann, D.H.5
-
25
-
-
84887992179
-
Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genome
-
Davoli T., Xu A.W., Mengwasser K.E., Sack L.M., Yoon J.C., Park P.J., et al. Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genome. Cell 2013, 155:948-962.
-
(2013)
Cell
, vol.155
, pp. 948-962
-
-
Davoli, T.1
Xu, A.W.2
Mengwasser, K.E.3
Sack, L.M.4
Yoon, J.C.5
Park, P.J.6
-
26
-
-
84899698299
-
Reduced NF1 expression confers resistance to EGFR inhibition in lung cancer
-
de Bruin E.C., Cowell C.F., Warne P.H., Jiang M., Saunders R.E., Melnick M.A., et al. Reduced NF1 expression confers resistance to EGFR inhibition in lung cancer. Cancer Discov 2014, 4:606-619.
-
(2014)
Cancer Discov
, vol.4
, pp. 606-619
-
-
de Bruin, E.C.1
Cowell, C.F.2
Warne, P.H.3
Jiang, M.4
Saunders, R.E.5
Melnick, M.A.6
-
27
-
-
80052557069
-
Exploiting cancer cell vulnerabilities to develop a combination therapy for ras-driven tumors
-
De Raedt T., Walton Z., Yecies J.L., Li D., Chen Y., Malone C.F., et al. Exploiting cancer cell vulnerabilities to develop a combination therapy for ras-driven tumors. Cancer Cell 2011, 20:400-413.
-
(2011)
Cancer Cell
, vol.20
, pp. 400-413
-
-
De Raedt, T.1
Walton, Z.2
Yecies, J.L.3
Li, D.4
Chen, Y.5
Malone, C.F.6
-
28
-
-
0026528368
-
Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis
-
DeClue J.E., Papageorge A.G., Fletcher J.A., Diehl S.R., Ratner N., Vass W.C., et al. Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis. Cell 1992, 69:265-273.
-
(1992)
Cell
, vol.69
, pp. 265-273
-
-
DeClue, J.E.1
Papageorge, A.G.2
Fletcher, J.A.3
Diehl, S.R.4
Ratner, N.5
Vass, W.C.6
-
29
-
-
54549094903
-
Somatic mutations affect key pathways in lung adenocarcinoma
-
Ding L., Getz G., Wheeler D.A., Mardis E.R., McLellan M.D., Cibulskis K., et al. Somatic mutations affect key pathways in lung adenocarcinoma. Nature 2008, 455:1069-1075.
-
(2008)
Nature
, vol.455
, pp. 1069-1075
-
-
Ding, L.1
Getz, G.2
Wheeler, D.A.3
Mardis, E.R.4
McLellan, M.D.5
Cibulskis, K.6
-
30
-
-
33749251431
-
Overexpression and diffuse expression pattern of IQGAP1 at invasion fronts are independent prognostic parameters in ovarian carcinomas
-
Dong P., Nabeshima K., Nishimura N., Kawakami T., Hachisuga T., Kawarabayashi T., et al. Overexpression and diffuse expression pattern of IQGAP1 at invasion fronts are independent prognostic parameters in ovarian carcinomas. Cancer Lett 2006, 243:120-127.
-
(2006)
Cancer Lett
, vol.243
, pp. 120-127
-
-
Dong, P.1
Nabeshima, K.2
Nishimura, N.3
Kawakami, T.4
Hachisuga, T.5
Kawarabayashi, T.6
-
31
-
-
20244385825
-
Aberrant promoter methylation in human DAB2 interactive protein (hDAB2IP) gene in gastrointestinal tumour
-
Dote H., Toyooka S., Tsukuda K., Yano M., Ota T., Murakami M., et al. Aberrant promoter methylation in human DAB2 interactive protein (hDAB2IP) gene in gastrointestinal tumour. Br J Cancer 2005, 92:1117-1125.
-
(2005)
Br J Cancer
, vol.92
, pp. 1117-1125
-
-
Dote, H.1
Toyooka, S.2
Tsukuda, K.3
Yano, M.4
Ota, T.5
Murakami, M.6
-
32
-
-
12144286741
-
Aberrant promoter methylation in human DAB2 interactive protein (hDAB2IP) gene in breast cancer
-
Dote H., Toyooka S., Tsukuda K., Yano M., Ouchida M., Doihara H., et al. Aberrant promoter methylation in human DAB2 interactive protein (hDAB2IP) gene in breast cancer. Clin Cancer Res 2004, 10:2082-2089.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 2082-2089
-
-
Dote, H.1
Toyooka, S.2
Tsukuda, K.3
Yano, M.4
Ouchida, M.5
Doihara, H.6
-
33
-
-
0347362524
-
Capillary malformation-arteriovenous malformation, a new clinical and genetic disorder caused by RASA1 mutations
-
Eerola I., Boon L.M., Mulliken J.B., Burrows P.E., Dompmartin A., Watanabe S., et al. Capillary malformation-arteriovenous malformation, a new clinical and genetic disorder caused by RASA1 mutations. Am J Hum Genet 2003, 73:1240-1249.
-
(2003)
Am J Hum Genet
, vol.73
, pp. 1240-1249
-
-
Eerola, I.1
Boon, L.M.2
Mulliken, J.B.3
Burrows, P.E.4
Dompmartin, A.5
Watanabe, S.6
-
34
-
-
0033560298
-
Increased mitogenicity of an alphabeta heterodimeric PDGF receptor complex correlates with lack of RasGAP binding
-
Ekman S., Thuresson E.R., Heldin C.H., Ronnstrand L. Increased mitogenicity of an alphabeta heterodimeric PDGF receptor complex correlates with lack of RasGAP binding. Oncogene 1999, 18:2481-2488.
-
(1999)
Oncogene
, vol.18
, pp. 2481-2488
-
-
Ekman, S.1
Thuresson, E.R.2
Heldin, C.H.3
Ronnstrand, L.4
-
35
-
-
0030859462
-
Identification of an actin cytoskeletal complex that includes IQGAP and the Cdc42 GTPase
-
Erickson J.W., Cerione R.A., Hart M.J. Identification of an actin cytoskeletal complex that includes IQGAP and the Cdc42 GTPase. JBiol Chem 1997, 272:24443-24447.
-
(1997)
JBiol Chem
, vol.272
, pp. 24443-24447
-
-
Erickson, J.W.1
Cerione, R.A.2
Hart, M.J.3
-
36
-
-
0026652899
-
Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways
-
Fantl W.J., Escobedo J.A., Martin G.A., Turck C.W., del Rosario M., McCormick F., et al. Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways. Cell 1992, 69:413-423.
-
(1992)
Cell
, vol.69
, pp. 413-423
-
-
Fantl, W.J.1
Escobedo, J.A.2
Martin, G.A.3
Turck, C.W.4
del Rosario, M.5
McCormick, F.6
-
37
-
-
1642573162
-
PKA phosphorylation and 14-3-3 interaction regulate the function of neurofibromatosis type I tumor suppressor, neurofibromin
-
Feng L., Yunoue S., Tokuo H., Ozawa T., Zhang D., Patrakitkomjorn S., et al. PKA phosphorylation and 14-3-3 interaction regulate the function of neurofibromatosis type I tumor suppressor, neurofibromin. FEBS Lett 2004, 557:275-282.
-
(2004)
FEBS Lett
, vol.557
, pp. 275-282
-
-
Feng, L.1
Yunoue, S.2
Tokuo, H.3
Ozawa, T.4
Zhang, D.5
Patrakitkomjorn, S.6
-
38
-
-
78651330430
-
COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer
-
Forbes S.A., Bindal N., Bamford S., Cole C., Kok C.Y., Beare D., et al. COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer. Nucleic Acids Res 2011, 39:D945-D950.
-
(2011)
Nucleic Acids Res
, vol.39
-
-
Forbes, S.A.1
Bindal, N.2
Bamford, S.3
Cole, C.4
Kok, C.Y.5
Beare, D.6
-
39
-
-
0027454104
-
Nonsense mutations in the C-terminal SH2 region of the GTPase activating protein (GAP) gene in human tumours
-
Friedman E., Gejman P.V., Martin G.A., McCormick F. Nonsense mutations in the C-terminal SH2 region of the GTPase activating protein (GAP) gene in human tumours. Nat Genet 1993, 5:242-247.
-
(1993)
Nat Genet
, vol.5
, pp. 242-247
-
-
Friedman, E.1
Gejman, P.V.2
Martin, G.A.3
McCormick, F.4
-
40
-
-
0033543551
-
Cdc42 and Rac1 regulate the interaction of IQGAP1 with beta-catenin
-
Fukata M., Kuroda S., Nakagawa M., Kawajiri A., Itoh N., Shoji I., et al. Cdc42 and Rac1 regulate the interaction of IQGAP1 with beta-catenin. JBiol Chem 1999, 274:26044-26050.
-
(1999)
JBiol Chem
, vol.274
, pp. 26044-26050
-
-
Fukata, M.1
Kuroda, S.2
Nakagawa, M.3
Kawajiri, A.4
Itoh, N.5
Shoji, I.6
-
41
-
-
18444369936
-
Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170
-
Fukata M., Watanabe T., Noritake J., Nakagawa M., Yamaga M., Kuroda S., et al. Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170. Cell 2002, 109:873-885.
-
(2002)
Cell
, vol.109
, pp. 873-885
-
-
Fukata, M.1
Watanabe, T.2
Noritake, J.3
Nakagawa, M.4
Yamaga, M.5
Kuroda, S.6
-
42
-
-
0033555967
-
Activation of mitogen-activated protein kinase associated with prostate cancer progression
-
Gioeli D., Mandell J.W., Petroni G.R., Frierson H.F., Weber M.J. Activation of mitogen-activated protein kinase associated with prostate cancer progression. Cancer Res 1999, 59:279-284.
-
(1999)
Cancer Res
, vol.59
, pp. 279-284
-
-
Gioeli, D.1
Mandell, J.W.2
Petroni, G.R.3
Frierson, H.F.4
Weber, M.J.5
-
43
-
-
0034708076
-
Aneurofibromatosis-1-regulated pathway is required for learning in Drosophila
-
Guo H.F., Tong J., Hannan F., Luo L., Zhong Y. Aneurofibromatosis-1-regulated pathway is required for learning in Drosophila. Nature 2000, 403:895-898.
-
(2000)
Nature
, vol.403
, pp. 895-898
-
-
Guo, H.F.1
Tong, J.2
Hannan, F.3
Luo, L.4
Zhong, Y.5
-
44
-
-
0032590071
-
IQGAP1 integrates Ca2+/calmodulin and Cdc42 signaling
-
Ho Y.D., Joyal J.L., Li Z., Sacks D.B. IQGAP1 integrates Ca2+/calmodulin and Cdc42 signaling. JBiol Chem 1999, 274:464-470.
-
(1999)
JBiol Chem
, vol.274
, pp. 464-470
-
-
Ho, Y.D.1
Joyal, J.L.2
Li, Z.3
Sacks, D.B.4
-
45
-
-
84864258996
-
Alandscape of driver mutations in melanoma
-
Hodis E., Watson I.R., Kryukov G.V., Arold S.T., Imielinski M., Theurillat J.P., et al. Alandscape of driver mutations in melanoma. Cell 2012, 150:251-263.
-
(2012)
Cell
, vol.150
, pp. 251-263
-
-
Hodis, E.1
Watson, I.R.2
Kryukov, G.V.3
Arold, S.T.4
Imielinski, M.5
Theurillat, J.P.6
-
46
-
-
84881508723
-
Identifying the Ubiquitin Ligase complex that regulates the NF1 tumor suppressor and Ras
-
Hollstein P.E., Cichowski K. Identifying the Ubiquitin Ligase complex that regulates the NF1 tumor suppressor and Ras. Cancer Discov 2013, 3:880-893.
-
(2013)
Cancer Discov
, vol.3
, pp. 880-893
-
-
Hollstein, P.E.1
Cichowski, K.2
-
47
-
-
77955038485
-
NF1 is a tumor suppressor in neuroblastoma that determines retinoic acid response and disease outcome
-
Holzel M., Huang S., Koster J., Ora I., Lakeman A., Caron H., et al. NF1 is a tumor suppressor in neuroblastoma that determines retinoic acid response and disease outcome. Cell 2010, 142:218-229.
-
(2010)
Cell
, vol.142
, pp. 218-229
-
-
Holzel, M.1
Huang, S.2
Koster, J.3
Ora, I.4
Lakeman, A.5
Caron, H.6
-
48
-
-
65549165975
-
Genetic alterations and oncogenic pathways associated with breast cancer subtypes
-
Hu X., Stern H.M., Ge L., O'Brien C., Haydu L., Honchell C.D., et al. Genetic alterations and oncogenic pathways associated with breast cancer subtypes. Mol Cancer Res 2009, 7:511-522.
-
(2009)
Mol Cancer Res
, vol.7
, pp. 511-522
-
-
Hu, X.1
Stern, H.M.2
Ge, L.3
O'Brien, C.4
Haydu, L.5
Honchell, C.D.6
-
49
-
-
0029897881
-
Phosphorylation of neurofibromatosis type 1 gene product (neurofibromin) by cAMP-dependent protein kinase
-
Izawa I., Tamaki N., Saya H. Phosphorylation of neurofibromatosis type 1 gene product (neurofibromin) by cAMP-dependent protein kinase. FEBS Lett 1996, 382:53-59.
-
(1996)
FEBS Lett
, vol.382
, pp. 53-59
-
-
Izawa, I.1
Tamaki, N.2
Saya, H.3
-
50
-
-
0028307836
-
Tumour predisposition in mice heterozygous for a targeted mutation in Nf1
-
Jacks T., Shih T.S., Schmitt E.M., Bronson R.T., Bernards A., Weinberg R.A. Tumour predisposition in mice heterozygous for a targeted mutation in Nf1. Nat Genet 1994, 7:353-361.
-
(1994)
Nat Genet
, vol.7
, pp. 353-361
-
-
Jacks, T.1
Shih, T.S.2
Schmitt, E.M.3
Bronson, R.T.4
Bernards, A.5
Weinberg, R.A.6
-
51
-
-
84877351889
-
IQGAP1 scaffold-kinase interaction blockade selectively targets RAS-MAP kinase-driven tumors
-
Jameson K.L., Mazur P.K., Zehnder A.M., Zhang J., Zarnegar B., Sage J., et al. IQGAP1 scaffold-kinase interaction blockade selectively targets RAS-MAP kinase-driven tumors. Nat Med 2013, 19:626-630.
-
(2013)
Nat Med
, vol.19
, pp. 626-630
-
-
Jameson, K.L.1
Mazur, P.K.2
Zehnder, A.M.3
Zhang, J.4
Zarnegar, B.5
Sage, J.6
-
52
-
-
58049220349
-
BRAF activation initiates but does not maintain invasive prostate adenocarcinoma
-
Jeong J.H., Wang Z., Guimaraes A.S., Ouyang X., Figueiredo J.L., Ding Z., et al. BRAF activation initiates but does not maintain invasive prostate adenocarcinoma. PLoS One 2008, 3:e3949.
-
(2008)
PLoS One
, vol.3
-
-
Jeong, J.H.1
Wang, Z.2
Guimaraes, A.S.3
Ouyang, X.4
Figueiredo, J.L.5
Ding, Z.6
-
53
-
-
84873809147
-
MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors
-
Jessen W.J., Miller S.J., Jousma E., Wu J., Rizvi T.A., Brundage M.E., et al. MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors. JClin Invest 2013, 123:340-347.
-
(2013)
JClin Invest
, vol.123
, pp. 340-347
-
-
Jessen, W.J.1
Miller, S.J.2
Jousma, E.3
Wu, J.4
Rizvi, T.A.5
Brundage, M.E.6
-
54
-
-
34547619642
-
Epigenetic silencing of a Ca(2+)-regulated Ras GTPase-activating protein RASAL defines a new mechanism of Ras activation in human cancers
-
Jin H., Wang X., Ying J., Wong A.H., Cui Y., Srivastava G., et al. Epigenetic silencing of a Ca(2+)-regulated Ras GTPase-activating protein RASAL defines a new mechanism of Ras activation in human cancers. Proc Natl Acad Sci U S A 2007, 104:12353-12358.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 12353-12358
-
-
Jin, H.1
Wang, X.2
Ying, J.3
Wong, A.H.4
Cui, Y.5
Srivastava, G.6
-
55
-
-
38749103163
-
IQGAP2 inactivation through aberrant promoter methylation and promotion of invasion in gastric cancer cells
-
Jin S.H., Akiyama Y., Fukamachi H., Yanagihara K., Akashi T., Yuasa Y. IQGAP2 inactivation through aberrant promoter methylation and promotion of invasion in gastric cancer cells. Int J Cancer 2008, 122:1040-1046.
-
(2008)
Int J Cancer
, vol.122
, pp. 1040-1046
-
-
Jin, S.H.1
Akiyama, Y.2
Fukamachi, H.3
Yanagihara, K.4
Akashi, T.5
Yuasa, Y.6
-
56
-
-
20844435467
-
The NF1 tumor suppressor critically regulates TSC2 and mTOR
-
Johannessen C.M., Reczek E.E., James M.F., Brems H., Legius E., Cichowski K. The NF1 tumor suppressor critically regulates TSC2 and mTOR. Proc Natl Acad Sci U S A 2005, 102:8573-8578.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 8573-8578
-
-
Johannessen, C.M.1
Reczek, E.E.2
James, M.F.3
Brems, H.4
Legius, E.5
Cichowski, K.6
-
57
-
-
38549102668
-
The loss of Nf1 transiently promotes self-renewal but not tumorigenesis by neural crest stem cells
-
Joseph N.M., Mosher J.T., Buchstaller J., Snider P., McKeever P.E., Lim M., et al. The loss of Nf1 transiently promotes self-renewal but not tumorigenesis by neural crest stem cells. Cancer Cell 2008, 13:129-140.
-
(2008)
Cancer Cell
, vol.13
, pp. 129-140
-
-
Joseph, N.M.1
Mosher, J.T.2
Buchstaller, J.3
Snider, P.4
McKeever, P.E.5
Lim, M.6
-
59
-
-
0025274965
-
Binding of GAP to activated PDGF receptors
-
Kazlauskas A., Ellis C., Pawson T., Cooper J.A. Binding of GAP to activated PDGF receptors. Science 1990, 247:1578-1581.
-
(1990)
Science
, vol.247
, pp. 1578-1581
-
-
Kazlauskas, A.1
Ellis, C.2
Pawson, T.3
Cooper, J.A.4
-
60
-
-
2942568167
-
Modulation of signalling by Sprouty: a developing story
-
Kim H.J., Bar-Sagi D. Modulation of signalling by Sprouty: a developing story. Nat Rev Mol Cell Biol 2004, 5:441-450.
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 441-450
-
-
Kim, H.J.1
Bar-Sagi, D.2
-
61
-
-
20444426889
-
Agenetic screen identifies PITX1 as a suppressor of RAS activity and tumorigenicity
-
Kolfschoten I.G., van Leeuwen B., Berns K., Mullenders J., Beijersbergen R.L., Bernards R., et al. Agenetic screen identifies PITX1 as a suppressor of RAS activity and tumorigenicity. Cell 2005, 121:849-858.
-
(2005)
Cell
, vol.121
, pp. 849-858
-
-
Kolfschoten, I.G.1
van Leeuwen, B.2
Berns, K.3
Mullenders, J.4
Beijersbergen, R.L.5
Bernards, R.6
-
62
-
-
0032763415
-
Deletions of the INK4A gene occur in malignant peripheral nerve sheath tumors but not in neurofibromas
-
Kourea H.P., Orlow I., Scheithauer B.W., Cordon-Cardo C., Woodruff J.M. Deletions of the INK4A gene occur in malignant peripheral nerve sheath tumors but not in neurofibromas. Am J Pathol 1999, 155:1855-1860.
-
(1999)
Am J Pathol
, vol.155
, pp. 1855-1860
-
-
Kourea, H.P.1
Orlow, I.2
Scheithauer, B.W.3
Cordon-Cardo, C.4
Woodruff, J.M.5
-
63
-
-
84865684161
-
Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma
-
Krauthammer M., Kong Y., Ha B.H., Evans P., Bacchiocchi A., McCusker J.P., et al. Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma. Nat Genet 2012, 44:1006-1014.
-
(2012)
Nat Genet
, vol.44
, pp. 1006-1014
-
-
Krauthammer, M.1
Kong, Y.2
Ha, B.H.3
Evans, P.4
Bacchiocchi, A.5
McCusker, J.P.6
-
64
-
-
0032493903
-
Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-cadherin- mediated cell-cell adhesion
-
Kuroda S., Fukata M., Nakagawa M., Fujii K., Nakamura T., Ookubo T., et al. Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-cadherin- mediated cell-cell adhesion. Science 1998, 281:832-835.
-
(1998)
Science
, vol.281
, pp. 832-835
-
-
Kuroda, S.1
Fukata, M.2
Nakagawa, M.3
Fujii, K.4
Nakamura, T.5
Ookubo, T.6
-
65
-
-
84865254848
-
Mechanisms of acquired resistance to targeted cancer therapies
-
Lackner M.R., Wilson T.R., Settleman J. Mechanisms of acquired resistance to targeted cancer therapies. Future Oncol 2012, 8:999-1014.
-
(2012)
Future Oncol
, vol.8
, pp. 999-1014
-
-
Lackner, M.R.1
Wilson, T.R.2
Settleman, J.3
-
66
-
-
0033799930
-
Loss of neurofibromin is associated with activation of RAS/MAPK and PI3-K/AKT signaling in a neurofibromatosis 1 astrocytoma
-
Lau N., Feldkamp M.M., Roncari L., Loehr A.H., Shannon P., Gutmann D.H., et al. Loss of neurofibromin is associated with activation of RAS/MAPK and PI3-K/AKT signaling in a neurofibromatosis 1 astrocytoma. JNeuropathol Exp Neurol 2000, 59:759-767.
-
(2000)
JNeuropathol Exp Neurol
, vol.59
, pp. 759-767
-
-
Lau, N.1
Feldkamp, M.M.2
Roncari, L.3
Loehr, A.H.4
Shannon, P.5
Gutmann, D.H.6
-
67
-
-
79959910771
-
Susceptible stages in Schwann cells for NF1-associated plexiform neurofibroma development
-
Le L.Q., Liu C., Shipman T., Chen Z., Suter U., Parada L.F. Susceptible stages in Schwann cells for NF1-associated plexiform neurofibroma development. Cancer Res 2011, 71:4686-4695.
-
(2011)
Cancer Res
, vol.71
, pp. 4686-4695
-
-
Le, L.Q.1
Liu, C.2
Shipman, T.3
Chen, Z.4
Suter, U.5
Parada, L.F.6
-
68
-
-
0028146806
-
TP53 mutations are frequent in malignant NF1 tumors
-
Legius E., Dierick H., Wu R., Hall B.K., Marynen P., Cassiman J.J., et al. TP53 mutations are frequent in malignant NF1 tumors. Genes Chromosom Cancer 1994, 10:250-255.
-
(1994)
Genes Chromosom Cancer
, vol.10
, pp. 250-255
-
-
Legius, E.1
Dierick, H.2
Wu, R.3
Hall, B.K.4
Marynen, P.5
Cassiman, J.J.6
-
69
-
-
0027468594
-
Somatic deletion of the neurofibromatosis type 1 gene in a neurofibrosarcoma supports a tumour suppressor gene hypothesis
-
Legius E., Marchuk D.A., Collins F.S., Glover T.W. Somatic deletion of the neurofibromatosis type 1 gene in a neurofibrosarcoma supports a tumour suppressor gene hypothesis. Nat Genet 1993, 3:122-126.
-
(1993)
Nat Genet
, vol.3
, pp. 122-126
-
-
Legius, E.1
Marchuk, D.A.2
Collins, F.S.3
Glover, T.W.4
-
70
-
-
0033861175
-
Ras activation in human breast cancer
-
von Lintig F.C., Dreilinger A.D., Varki N.M., Wallace A.M., Casteel D.E., Boss G.R. Ras activation in human breast cancer. Breast Cancer Res Treat 2000, 62:51-62.
-
(2000)
Breast Cancer Res Treat
, vol.62
, pp. 51-62
-
-
von Lintig, F.C.1
Dreilinger, A.D.2
Varki, N.M.3
Wallace, A.M.4
Casteel, D.E.5
Boss, G.R.6
-
71
-
-
84890466783
-
Identification of RASAL1 as a major tumor suppressor gene in thyroid cancer
-
Liu D., Yang C., Bojdani E., Murugan A.K., Xing M. Identification of RASAL1 as a major tumor suppressor gene in thyroid cancer. JNatl Cancer Inst 2013, 105:1617-1627.
-
(2013)
JNatl Cancer Inst
, vol.105
, pp. 1617-1627
-
-
Liu, D.1
Yang, C.2
Bojdani, E.3
Murugan, A.K.4
Xing, M.5
-
72
-
-
34547796898
-
Molecular dissection of isolated disease features in mosaic neurofibromatosis type 1
-
Maertens O., De Schepper S., Vandesompele J., Brems H., Heyns I., Janssens S., et al. Molecular dissection of isolated disease features in mosaic neurofibromatosis type 1. Am J Hum Genet 2007, 81:243-251.
-
(2007)
Am J Hum Genet
, vol.81
, pp. 243-251
-
-
Maertens, O.1
De Schepper, S.2
Vandesompele, J.3
Brems, H.4
Heyns, I.5
Janssens, S.6
-
73
-
-
84876037369
-
Elucidating distinct roles for NF1 in melanomagenesis
-
Maertens O., Johnson B., Hollstein P., Frederick D.T., Cooper Z.A., Messiaen L., et al. Elucidating distinct roles for NF1 in melanomagenesis. Cancer Discov 2013, 3:338-349.
-
(2013)
Cancer Discov
, vol.3
, pp. 338-349
-
-
Maertens, O.1
Johnson, B.2
Hollstein, P.3
Frederick, D.T.4
Cooper, Z.A.5
Messiaen, L.6
-
74
-
-
0036554734
-
Immunohistochemical demonstration of phospho-Akt in high Gleason grade prostate cancer
-
Malik S.N., Brattain M., Ghosh P.M., Troyer D.A., Prihoda T., Bedolla R., et al. Immunohistochemical demonstration of phospho-Akt in high Gleason grade prostate cancer. Clin Cancer Res 2002, 8:1168-1171.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1168-1171
-
-
Malik, S.N.1
Brattain, M.2
Ghosh, P.M.3
Troyer, D.A.4
Prihoda, T.5
Bedolla, R.6
-
75
-
-
0025630506
-
The tyrosine phosphorylated carboxyterminus of the EGF receptor is a binding site for GAP and PLC-gamma
-
Margolis B., Li N., Koch A., Mohammadi M., Hurwitz D.R., Zilberstein A., et al. The tyrosine phosphorylated carboxyterminus of the EGF receptor is a binding site for GAP and PLC-gamma. EMBO J 1990, 9:4375-4380.
-
(1990)
EMBO J
, vol.9
, pp. 4375-4380
-
-
Margolis, B.1
Li, N.2
Koch, A.3
Mohammadi, M.4
Hurwitz, D.R.5
Zilberstein, A.6
-
76
-
-
0025251137
-
The GAP-related domain of the neurofibromatosis type 1 gene product interacts with ras p21
-
Martin G.A., Viskochil D., Bollag G., McCabe P.C., Crosier W.J., Haubruck H., et al. The GAP-related domain of the neurofibromatosis type 1 gene product interacts with ras p21. Cell 1990, 63:843-849.
-
(1990)
Cell
, vol.63
, pp. 843-849
-
-
Martin, G.A.1
Viskochil, D.2
Bollag, G.3
McCabe, P.C.4
Crosier, W.J.5
Haubruck, H.6
-
77
-
-
79959861743
-
Perinatal or adult Nf1 inactivation using tamoxifen-inducible PlpCre each cause neurofibroma formation
-
Mayes D.A., Rizvi T.A., Cancelas J.A., Kolasinski N.T., Ciraolo G.M., Stemmer-Rachamimov A.O., et al. Perinatal or adult Nf1 inactivation using tamoxifen-inducible PlpCre each cause neurofibroma formation. Cancer Res 2011, 71:4675-4685.
-
(2011)
Cancer Res
, vol.71
, pp. 4675-4685
-
-
Mayes, D.A.1
Rizvi, T.A.2
Cancelas, J.A.3
Kolasinski, N.T.4
Ciraolo, G.M.5
Stemmer-Rachamimov, A.O.6
-
78
-
-
34247866468
-
IQGAP1 and IGFBP2: valuable biomarkers for determining prognosis in glioma patients
-
McDonald K.L., O'Sullivan M.G., Parkinson J.F., Shaw J.M., Payne C.A., Brewer J.M., et al. IQGAP1 and IGFBP2: valuable biomarkers for determining prognosis in glioma patients. JNeuropathol Exp Neurol 2007, 66:405-417.
-
(2007)
JNeuropathol Exp Neurol
, vol.66
, pp. 405-417
-
-
McDonald, K.L.1
O'Sullivan, M.G.2
Parkinson, J.F.3
Shaw, J.M.4
Payne, C.A.5
Brewer, J.M.6
-
79
-
-
67649321430
-
Proteasomal and genetic inactivation of the NF1 tumor suppressor in gliomagenesis
-
McGillicuddy L.T., Fromm J.A., Hollstein P.E., Kubek S., Beroukhim R., De Raedt T., et al. Proteasomal and genetic inactivation of the NF1 tumor suppressor in gliomagenesis. Cancer Cell 2009, 16:44-54.
-
(2009)
Cancer Cell
, vol.16
, pp. 44-54
-
-
McGillicuddy, L.T.1
Fromm, J.A.2
Hollstein, P.E.3
Kubek, S.4
Beroukhim, R.5
De Raedt, T.6
-
80
-
-
84883618312
-
The RasGAP gene, RASAL2, is a tumor and metastasis suppressor
-
McLaughlin S.K., Olsen S.N., Dake B., De Raedt T., Lim E., Bronson R.T., et al. The RasGAP gene, RASAL2, is a tumor and metastasis suppressor. Cancer Cell 2013, 24:365-378.
-
(2013)
Cancer Cell
, vol.24
, pp. 365-378
-
-
McLaughlin, S.K.1
Olsen, S.N.2
Dake, B.3
De Raedt, T.4
Lim, E.5
Bronson, R.T.6
-
81
-
-
84857377978
-
Genome-wide functional screen identifies a compendium of genes affecting sensitivity to tamoxifen
-
Mendes-Pereira A.M., Sims D., Dexter T., Fenwick K., Assiotis I., Kozarewa I., et al. Genome-wide functional screen identifies a compendium of genes affecting sensitivity to tamoxifen. Proc Natl Acad Sci U S A 2012, 109:2730-2735.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 2730-2735
-
-
Mendes-Pereira, A.M.1
Sims, D.2
Dexter, T.3
Fenwick, K.4
Assiotis, I.5
Kozarewa, I.6
-
82
-
-
77749297990
-
An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-kappaB
-
Min J., Zaslavsky A., Fedele G., McLaughlin S.K., Reczek E.E., De Raedt T., et al. An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-kappaB. Nat Med 2010, 16:286-294.
-
(2010)
Nat Med
, vol.16
, pp. 286-294
-
-
Min, J.1
Zaslavsky, A.2
Fedele, G.3
McLaughlin, S.K.4
Reczek, E.E.5
De Raedt, T.6
-
83
-
-
0034691562
-
Potential prognostic value of mitogen-activated protein kinase activity for disease-free survival of primary breast cancer patients
-
Mueller H., Flury N., Eppenberger-Castori S., Kueng W., David F., Eppenberger U. Potential prognostic value of mitogen-activated protein kinase activity for disease-free survival of primary breast cancer patients. Int J Cancer 2000, 89:384-388.
-
(2000)
Int J Cancer
, vol.89
, pp. 384-388
-
-
Mueller, H.1
Flury, N.2
Eppenberger-Castori, S.3
Kueng, W.4
David, F.5
Eppenberger, U.6
-
84
-
-
0037039718
-
Immunohistochemical analysis of IQGAP1 expression in human colorectal carcinomas: its overexpression in carcinomas and association with invasion fronts
-
Nabeshima K., Shimao Y., Inoue T., Koono M. Immunohistochemical analysis of IQGAP1 expression in human colorectal carcinomas: its overexpression in carcinomas and association with invasion fronts. Cancer Lett 2002, 176:101-109.
-
(2002)
Cancer Lett
, vol.176
, pp. 101-109
-
-
Nabeshima, K.1
Shimao, Y.2
Inoue, T.3
Koono, M.4
-
85
-
-
0032762784
-
Malignant transformation of neurofibromas in neurofibromatosis 1 is associated with CDKN2A/p16 inactivation
-
Nielsen G.P., Stemmer-Rachamimov A.O., Ino Y., Moller M.B., Rosenberg A.E., Louis D.N. Malignant transformation of neurofibromas in neurofibromatosis 1 is associated with CDKN2A/p16 inactivation. Am J Pathol 1999, 155:1879-1884.
-
(1999)
Am J Pathol
, vol.155
, pp. 1879-1884
-
-
Nielsen, G.P.1
Stemmer-Rachamimov, A.O.2
Ino, Y.3
Moller, M.B.4
Rosenberg, A.E.5
Louis, D.N.6
-
86
-
-
84899513979
-
Loss of NF1 in cutaneous melanoma is associated with RAS activation and MEK dependence
-
Nissan M.H., Pratilas C.A., Jones A.M., Ramirez R., Won H., Liu C., et al. Loss of NF1 in cutaneous melanoma is associated with RAS activation and MEK dependence. Cancer Res 2014, 74:2340-2350.
-
(2014)
Cancer Res
, vol.74
, pp. 2340-2350
-
-
Nissan, M.H.1
Pratilas, C.A.2
Jones, A.M.3
Ramirez, R.4
Won, H.5
Liu, C.6
-
87
-
-
59849104569
-
Decreased expression of the RAS-GTPase activating protein RASAL1 is associated with colorectal tumor progression
-
Ohta M., Seto M., Ijichi H., Miyabayashi K., Kudo Y., Mohri D., et al. Decreased expression of the RAS-GTPase activating protein RASAL1 is associated with colorectal tumor progression. Gastroenterology 2009, 136:206-216.
-
(2009)
Gastroenterology
, vol.136
, pp. 206-216
-
-
Ohta, M.1
Seto, M.2
Ijichi, H.3
Miyabayashi, K.4
Kudo, Y.5
Mohri, D.6
-
88
-
-
42049109923
-
Activator protein-1 transcription factors are associated with progression and recurrence of prostate cancer
-
Ouyang X., Jessen W.J., Al-Ahmadie H., Serio A.M., Lin Y., Shih W.J., et al. Activator protein-1 transcription factors are associated with progression and recurrence of prostate cancer. Cancer Res 2008, 68:2132-2144.
-
(2008)
Cancer Res
, vol.68
, pp. 2132-2144
-
-
Ouyang, X.1
Jessen, W.J.2
Al-Ahmadie, H.3
Serio, A.M.4
Lin, Y.5
Shih, W.J.6
-
89
-
-
52949127312
-
An integrated genomic analysis of human glioblastoma multiforme
-
Parsons D.W., Jones S., Zhang X., Lin J.C., Leary R.J., Angenendt P., et al. An integrated genomic analysis of human glioblastoma multiforme. Science 2008, 321:1807-1812.
-
(2008)
Science
, vol.321
, pp. 1807-1812
-
-
Parsons, D.W.1
Jones, S.2
Zhang, X.3
Lin, J.C.4
Leary, R.J.5
Angenendt, P.6
-
92
-
-
2342424547
-
IQGAP1 binds ERK2 and modulates its activity
-
Roy M., Li Z., Sacks D.B. IQGAP1 binds ERK2 and modulates its activity. JBiol Chem 2004, 279:17329-17337.
-
(2004)
JBiol Chem
, vol.279
, pp. 17329-17337
-
-
Roy, M.1
Li, Z.2
Sacks, D.B.3
-
93
-
-
24344491858
-
IQGAP1 is a scaffold for mitogen-activated protein kinase signaling
-
Roy M., Li Z., Sacks D.B. IQGAP1 is a scaffold for mitogen-activated protein kinase signaling. Mol Cell Biol 2005, 25:7940-7952.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 7940-7952
-
-
Roy, M.1
Li, Z.2
Sacks, D.B.3
-
94
-
-
0034639937
-
Genetic and cellular defects contributing to benign tumor formation in neurofibromatosis type 1
-
Rutkowski J.L., Wu K., Gutmann D.H., Boyer P.J., Legius E. Genetic and cellular defects contributing to benign tumor formation in neurofibromatosis type 1. Hum Mol Genet 2000, 9:1059-1066.
-
(2000)
Hum Mol Genet
, vol.9
, pp. 1059-1066
-
-
Rutkowski, J.L.1
Wu, K.2
Gutmann, D.H.3
Boyer, P.J.4
Legius, E.5
-
95
-
-
39749108409
-
Development of hepatocellular carcinoma in Iqgap2-deficient mice is IQGAP1 dependent
-
Schmidt V.A., Chiariello C.S., Capilla E., Miller F., Bahou W.F. Development of hepatocellular carcinoma in Iqgap2-deficient mice is IQGAP1 dependent. Mol Cell Biol 2008, 28:1489-1502.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 1489-1502
-
-
Schmidt, V.A.1
Chiariello, C.S.2
Capilla, E.3
Miller, F.4
Bahou, W.F.5
-
96
-
-
84888001513
-
Anew world of Polycombs: unexpected partnerships and emerging functions
-
Schwartz Y.B., Pirrotta V. Anew world of Polycombs: unexpected partnerships and emerging functions. Nat Rev Genet 2013, 14:853-864.
-
(2013)
Nat Rev Genet
, vol.14
, pp. 853-864
-
-
Schwartz, Y.B.1
Pirrotta, V.2
-
97
-
-
0034642298
-
Schwann cells harbor the somatic NF1 mutation in neurofibromas: evidence of two different Schwann cell subpopulations
-
Serra E., Rosenbaum T., Winner U., Aledo R., Ars E., Estivill X., et al. Schwann cells harbor the somatic NF1 mutation in neurofibromas: evidence of two different Schwann cell subpopulations. Hum Mol Genet 2000, 9:3055-3064.
-
(2000)
Hum Mol Genet
, vol.9
, pp. 3055-3064
-
-
Serra, E.1
Rosenbaum, T.2
Winner, U.3
Aledo, R.4
Ars, E.5
Estivill, X.6
-
98
-
-
79551497868
-
Reduced expression of RAS protein activator like-1 in gastric cancer
-
Seto M., Ohta M., Ikenoue T., Sugimoto T., Asaoka Y., Tada M., et al. Reduced expression of RAS protein activator like-1 in gastric cancer. Int J Cancer 2011, 128:1293-1302.
-
(2011)
Int J Cancer
, vol.128
, pp. 1293-1302
-
-
Seto, M.1
Ohta, M.2
Ikenoue, T.3
Sugimoto, T.4
Asaoka, Y.5
Tada, M.6
-
99
-
-
0027979146
-
Loss of the normal NF1 allele from the bone marrow of children with type 1 neurofibromatosis and malignant myeloid disorders
-
Shannon K.M., O'Connell P., Martin G.A., Paderanga D., Olson K., Dinndorf P., et al. Loss of the normal NF1 allele from the bone marrow of children with type 1 neurofibromatosis and malignant myeloid disorders. NEngl J Med 1994, 330:597-601.
-
(1994)
NEngl J Med
, vol.330
, pp. 597-601
-
-
Shannon, K.M.1
O'Connell, P.2
Martin, G.A.3
Paderanga, D.4
Olson, K.5
Dinndorf, P.6
-
100
-
-
34547106591
-
Pten inactivation and the emergence of androgen-independent prostate cancer
-
Shen M.M., Abate-Shen C. Pten inactivation and the emergence of androgen-independent prostate cancer. Cancer Res 2007, 67:6535-6538.
-
(2007)
Cancer Res
, vol.67
, pp. 6535-6538
-
-
Shen, M.M.1
Abate-Shen, C.2
-
101
-
-
55949136562
-
Roles of the EZH2 histone methyltransferase in cancer epigenetics
-
Simon J.A., Lange C.A. Roles of the EZH2 histone methyltransferase in cancer epigenetics. Mutat Res 2008, 647:21-29.
-
(2008)
Mutat Res
, vol.647
, pp. 21-29
-
-
Simon, J.A.1
Lange, C.A.2
-
102
-
-
0030946366
-
Hyperexpression of mitogen-activated protein kinase in human breast cancer
-
Sivaraman V.S., Wang H., Nuovo G.J., Malbon C.C. Hyperexpression of mitogen-activated protein kinase in human breast cancer. JClin Invest 1997, 99:1478-1483.
-
(1997)
JClin Invest
, vol.99
, pp. 1478-1483
-
-
Sivaraman, V.S.1
Wang, H.2
Nuovo, G.J.3
Malbon, C.C.4
-
103
-
-
33749993417
-
The consensus coding sequences of human breast and colorectal cancers
-
Sjoblom T., Jones S., Wood L.D., Parsons D.W., Lin J., Barber T.D., et al. The consensus coding sequences of human breast and colorectal cancers. Science 2006, 314:268-274.
-
(2006)
Science
, vol.314
, pp. 268-274
-
-
Sjoblom, T.1
Jones, S.2
Wood, L.D.3
Parsons, D.W.4
Lin, J.5
Barber, T.D.6
-
104
-
-
84860217431
-
The functions and regulation of the PTEN tumour suppressor
-
Song M.S., Salmena L., Pandolfi P.P. The functions and regulation of the PTEN tumour suppressor. Nat Rev Mol Cell Biol 2012, 13:283-296.
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 283-296
-
-
Song, M.S.1
Salmena, L.2
Pandolfi, P.P.3
-
105
-
-
84863643200
-
Ashared molecular mechanism underlies the human rasopathies Legius syndrome and Neurofibromatosis-1
-
Stowe I.B., Mercado E.L., Stowe T.R., Bell E.L., Oses-Prieto J.A., Hernandez H., et al. Ashared molecular mechanism underlies the human rasopathies Legius syndrome and Neurofibromatosis-1. Genes Dev 2012, 26:1421-1426.
-
(2012)
Genes Dev
, vol.26
, pp. 1421-1426
-
-
Stowe, I.B.1
Mercado, E.L.2
Stowe, T.R.3
Bell, E.L.4
Oses-Prieto, J.A.5
Hernandez, H.6
-
106
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
TCGA
-
TCGA Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 2008, 455:1061-1068.
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
-
107
-
-
79959838081
-
Integrated genomic analyses of ovarian carcinoma
-
TCGA
-
TCGA Integrated genomic analyses of ovarian carcinoma. Nature 2011, 474:609-615.
-
(2011)
Nature
, vol.474
, pp. 609-615
-
-
-
108
-
-
84877028141
-
Comprehensive molecular portraits of human breast tumours
-
TCGA
-
TCGA Comprehensive molecular portraits of human breast tumours. Nature 2012, 490:61-70.
-
(2012)
Nature
, vol.490
, pp. 61-70
-
-
-
109
-
-
0035815448
-
Phosphorylation of neurofibromin by cAMP-dependent protein kinase is regulated via a cellular association of N(G),N(G)-dimethylarginine dimethylaminohydrolase
-
Tokuo H., Yunoue S., Feng L., Kimoto M., Tsuji H., Ono T., et al. Phosphorylation of neurofibromin by cAMP-dependent protein kinase is regulated via a cellular association of N(G),N(G)-dimethylarginine dimethylaminohydrolase. FEBS Lett 2001, 494:48-53.
-
(2001)
FEBS Lett
, vol.494
, pp. 48-53
-
-
Tokuo, H.1
Yunoue, S.2
Feng, L.3
Kimoto, M.4
Tsuji, H.5
Ono, T.6
-
110
-
-
0036159132
-
Neurofibromin regulates G protein-stimulated adenylyl cyclase activity
-
Tong J., Hannan F., Zhu Y., Bernards A., Zhong Y. Neurofibromin regulates G protein-stimulated adenylyl cyclase activity. Nat Neurosci 2002, 5:95-96.
-
(2002)
Nat Neurosci
, vol.5
, pp. 95-96
-
-
Tong, J.1
Hannan, F.2
Zhu, Y.3
Bernards, A.4
Zhong, Y.5
-
111
-
-
0024212303
-
Molecular cloning of two types of GAP complementary DNA from human placenta
-
Trahey M., Wong G., Halenbeck R., Rubinfeld B., Martin G.A., Ladner M., et al. Molecular cloning of two types of GAP complementary DNA from human placenta. Science 1988, 242:1697-1700.
-
(1988)
Science
, vol.242
, pp. 1697-1700
-
-
Trahey, M.1
Wong, G.2
Halenbeck, R.3
Rubinfeld, B.4
Martin, G.A.5
Ladner, M.6
-
112
-
-
84901434983
-
-
Neurofibromatosis Type 1, (Berlin Heidelberg: Springer-Verlag)
-
Upadhyaya, M., and Cooper, D. N. (2012). Neurofibromatosis Type 1, (Berlin Heidelberg: Springer-Verlag).
-
(2012)
-
-
Upadhyaya, M.1
Cooper, D.N.2
-
113
-
-
84891894051
-
The genetic landscape of clinical resistance to RAF inhibition in metastatic melanoma
-
Van Allen E.M., Wagle N., Sucker A., Treacy D.J., Johannessen C.M., Goetz E.M., et al. The genetic landscape of clinical resistance to RAF inhibition in metastatic melanoma. Cancer Discov 2014, 4:94-109.
-
(2014)
Cancer Discov
, vol.4
, pp. 94-109
-
-
Van Allen, E.M.1
Wagle, N.2
Sucker, A.3
Treacy, D.J.4
Johannessen, C.M.5
Goetz, E.M.6
-
114
-
-
0032786494
-
Mouse tumor model for neurofibromatosis type 1
-
Vogel K.S., Klesse L.J., Velasco-Miguel S., Meyers K., Rushing E.J., Parada L.F. Mouse tumor model for neurofibromatosis type 1. Science 1999, 286:2176-2179.
-
(1999)
Science
, vol.286
, pp. 2176-2179
-
-
Vogel, K.S.1
Klesse, L.J.2
Velasco-Miguel, S.3
Meyers, K.4
Rushing, E.J.5
Parada, L.F.6
-
115
-
-
0023681723
-
Cloning of bovine GAP and its interaction with oncogenic ras p21
-
Vogel U.S., Dixon R.A., Schaber M.D., Diehl R.E., Marshall M.S., Scolnick E.M., et al. Cloning of bovine GAP and its interaction with oncogenic ras p21. Nature 1988, 335:90-93.
-
(1988)
Nature
, vol.335
, pp. 90-93
-
-
Vogel, U.S.1
Dixon, R.A.2
Schaber, M.D.3
Diehl, R.E.4
Marshall, M.S.5
Scolnick, E.M.6
-
116
-
-
84888253172
-
Genetic and functional studies implicate synaptic overgrowth and ring gland cAMP/PKA signaling defects in the Drosophila melanogaster neurofibromatosis-1 growth deficiency
-
Walker J.A., Gouzi J.Y., Long J.B., Huang S., Maher R.C., Xia H., et al. Genetic and functional studies implicate synaptic overgrowth and ring gland cAMP/PKA signaling defects in the Drosophila melanogaster neurofibromatosis-1 growth deficiency. PLoS Genet 2013, 9:e1003958.
-
(2013)
PLoS Genet
, vol.9
-
-
Walker, J.A.1
Gouzi, J.Y.2
Long, J.B.3
Huang, S.4
Maher, R.C.5
Xia, H.6
-
117
-
-
33947319976
-
IQGAP3, a novel effector of Rac1 and Cdc42, regulates neurite outgrowth
-
Wang S., Watanabe T., Noritake J., Fukata M., Yoshimura T., Itoh N., et al. IQGAP3, a novel effector of Rac1 and Cdc42, regulates neurite outgrowth. JCell Sci 2007, 120:567-577.
-
(2007)
JCell Sci
, vol.120
, pp. 567-577
-
-
Wang, S.1
Watanabe, T.2
Noritake, J.3
Fukata, M.4
Yoshimura, T.5
Itoh, N.6
-
118
-
-
84892749369
-
Genetic screens in human cells using the CRISPR-Cas9 system
-
Wang T., Wei J.J., Sabatini D.M., Lander E.S. Genetic screens in human cells using the CRISPR-Cas9 system. Science 2014, 343:80-84.
-
(2014)
Science
, vol.343
, pp. 80-84
-
-
Wang, T.1
Wei, J.J.2
Sabatini, D.M.3
Lander, E.S.4
-
119
-
-
84886290834
-
Overexpression of IQGAP1 in human pancreatic cancer
-
Wang X.X., Li X.Z., Zhai L.Q., Liu Z.R., Chen X.J., Pei Y. Overexpression of IQGAP1 in human pancreatic cancer. Hepatobiliary Pancreat Dis Int 2013, 12:540-545.
-
(2013)
Hepatobiliary Pancreat Dis Int
, vol.12
, pp. 540-545
-
-
Wang, X.X.1
Li, X.Z.2
Zhai, L.Q.3
Liu, Z.R.4
Chen, X.J.5
Pei, Y.6
-
120
-
-
0028033549
-
Identification of a human rasGAP-related protein containing calmodulin-binding motifs
-
Weissbach L., Settleman J., Kalady M.F., Snijders A.J., Murthy A.E., Yan Y.X., et al. Identification of a human rasGAP-related protein containing calmodulin-binding motifs. JBiol Chem 1994, 269:20517-20521.
-
(1994)
JBiol Chem
, vol.269
, pp. 20517-20521
-
-
Weissbach, L.1
Settleman, J.2
Kalady, M.F.3
Snijders, A.J.4
Murthy, A.E.5
Yan, Y.X.6
-
121
-
-
33846396338
-
The sec14 homology module of neurofibromin binds cellular glycerophospholipids: mass spectrometry and structure of a lipid complex
-
Welti S., Fraterman S., D'Angelo I., Wilm M., Scheffzek K. The sec14 homology module of neurofibromin binds cellular glycerophospholipids: mass spectrometry and structure of a lipid complex. JMol Biol 2007, 366:551-562.
-
(2007)
JMol Biol
, vol.366
, pp. 551-562
-
-
Welti, S.1
Fraterman, S.2
D'Angelo, I.3
Wilm, M.4
Scheffzek, K.5
-
122
-
-
67349198476
-
IQGAPs in cancer: a family of scaffold proteins underlying tumorigenesis
-
White C.D., Brown M.D., Sacks D.B. IQGAPs in cancer: a family of scaffold proteins underlying tumorigenesis. FEBS Lett 2009, 583:1817-1824.
-
(2009)
FEBS Lett
, vol.583
, pp. 1817-1824
-
-
White, C.D.1
Brown, M.D.2
Sacks, D.B.3
-
123
-
-
84856219974
-
IQGAP1 and its binding proteins control diverse biological functions
-
White C.D., Erdemir H.H., Sacks D.B. IQGAP1 and its binding proteins control diverse biological functions. Cell Signal 2012, 24:826-834.
-
(2012)
Cell Signal
, vol.24
, pp. 826-834
-
-
White, C.D.1
Erdemir, H.H.2
Sacks, D.B.3
-
124
-
-
77958137062
-
IQGAP1 and IQGAP2 are reciprocally altered in hepatocellular carcinoma
-
White C.D., Khurana H., Gnatenko D.V., Li Z., Odze R.D., Sacks D.B., et al. IQGAP1 and IQGAP2 are reciprocally altered in hepatocellular carcinoma. BMC Gastroenterol 2010, 10:125.
-
(2010)
BMC Gastroenterol
, vol.10
, pp. 125
-
-
White, C.D.1
Khurana, H.2
Gnatenko, D.V.3
Li, Z.4
Odze, R.D.5
Sacks, D.B.6
-
125
-
-
84875717480
-
Agenome-scale RNA interference screen implicates NF1 loss in resistance to RAF inhibition
-
Whittaker S.R., Theurillat J.P., Van Allen E., Wagle N., Hsiao J., Cowley G.S., et al. Agenome-scale RNA interference screen implicates NF1 loss in resistance to RAF inhibition. Cancer Discov 2013, 3:350-362.
-
(2013)
Cancer Discov
, vol.3
, pp. 350-362
-
-
Whittaker, S.R.1
Theurillat, J.P.2
Van Allen, E.3
Wagle, N.4
Hsiao, J.5
Cowley, G.S.6
-
126
-
-
38549108007
-
Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells
-
Wu J., Williams J.P., Rizvi T.A., Kordich J.J., Witte D., Meijer D., et al. Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells. Cancer Cell 2008, 13:105-116.
-
(2008)
Cancer Cell
, vol.13
, pp. 105-116
-
-
Wu, J.1
Williams, J.P.2
Rizvi, T.A.3
Kordich, J.J.4
Witte, D.5
Meijer, D.6
-
127
-
-
84899446436
-
The role of DAB2IP in androgen receptor activation during prostate cancer progression
-
Wu K., Liu J., Tseng S.F., Gore C., Ning Z., Sharifi N., et al. The role of DAB2IP in androgen receptor activation during prostate cancer progression. Oncogene 2014, 33:1954-1963.
-
(2014)
Oncogene
, vol.33
, pp. 1954-1963
-
-
Wu, K.1
Liu, J.2
Tseng, S.F.3
Gore, C.4
Ning, Z.5
Sharifi, N.6
-
128
-
-
77249104533
-
Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis
-
Xie D., Gore C., Liu J., Pong R.C., Mason R., Hao G., et al. Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis. Proc Natl Acad Sci U S A 2010, 107:2485-2490.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 2485-2490
-
-
Xie, D.1
Gore, C.2
Liu, J.3
Pong, R.C.4
Mason, R.5
Hao, G.6
-
129
-
-
0025244911
-
The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae
-
Xu G.F., Lin B., Tanaka K., Dunn D., Wood D., Gesteland R., et al. The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae. Cell 1990, 63:835-841.
-
(1990)
Cell
, vol.63
, pp. 835-841
-
-
Xu, G.F.1
Lin, B.2
Tanaka, K.3
Dunn, D.4
Wood, D.5
Gesteland, R.6
-
130
-
-
0026655421
-
Loss of NF1 alleles in phaeochromocytomas from patients with type I neurofibromatosis
-
Xu W., Mulligan L.M., Ponder M.A., Liu L., Smith B.A., Mathew C.G., et al. Loss of NF1 alleles in phaeochromocytomas from patients with type I neurofibromatosis. Genes Chromosom Cancer 1992, 4:337-342.
-
(1992)
Genes Chromosom Cancer
, vol.4
, pp. 337-342
-
-
Xu, W.1
Mulligan, L.M.2
Ponder, M.A.3
Liu, L.4
Smith, B.A.5
Mathew, C.G.6
-
131
-
-
62649119164
-
P120Ras-GAP binds the DLC1 Rho-GAP tumor suppressor protein and inhibits its RhoA GTPase and growth-suppressing activities
-
Yang X.Y., Guan M., Vigil D., Der C.J., Lowy D.R., Popescu N.C. p120Ras-GAP binds the DLC1 Rho-GAP tumor suppressor protein and inhibits its RhoA GTPase and growth-suppressing activities. Oncogene 2009, 28:1401-1409.
-
(2009)
Oncogene
, vol.28
, pp. 1401-1409
-
-
Yang, X.Y.1
Guan, M.2
Vigil, D.3
Der, C.J.4
Lowy, D.R.5
Popescu, N.C.6
-
132
-
-
8644278076
-
Aberrant promoter methylation of human DAB2 interactive protein (hDAB2IP) gene in lung cancers
-
Yano M., Toyooka S., Tsukuda K., Dote H., Ouchida M., Hanabata T., et al. Aberrant promoter methylation of human DAB2 interactive protein (hDAB2IP) gene in lung cancers. Int J Cancer 2005, 113:59-66.
-
(2005)
Int J Cancer
, vol.113
, pp. 59-66
-
-
Yano, M.1
Toyooka, S.2
Tsukuda, K.3
Dote, H.4
Ouchida, M.5
Hanabata, T.6
-
133
-
-
36349017912
-
Apolycomb repression signature in metastatic prostate cancer predicts cancer outcome
-
Yu J., Yu J., Rhodes D.R., Tomlins S.A., Cao X., Chen G., et al. Apolycomb repression signature in metastatic prostate cancer predicts cancer outcome. Cancer Res 2007, 67:10657-10663.
-
(2007)
Cancer Res
, vol.67
, pp. 10657-10663
-
-
Yu, J.1
Yu, J.2
Rhodes, D.R.3
Tomlins, S.A.4
Cao, X.5
Chen, G.6
-
134
-
-
7244253045
-
AIP1/DAB2IP, a novel member of the Ras-GAP family, transduces TRAF2-induced ASK1-JNK activation
-
Zhang H., Zhang R., Luo Y., D'Alessio A., Pober J.S., Min W. AIP1/DAB2IP, a novel member of the Ras-GAP family, transduces TRAF2-induced ASK1-JNK activation. JBiol Chem 2004, 279:44955-44965.
-
(2004)
JBiol Chem
, vol.279
, pp. 44955-44965
-
-
Zhang, H.1
Zhang, R.2
Luo, Y.3
D'Alessio, A.4
Pober, J.S.5
Min, W.6
-
135
-
-
84861469842
-
Low expression of DAB2IP contributes to malignant development and poor prognosis in hepatocellular carcinoma
-
Zhang X., Li N., Li X., Zhao W., Qiao Y., Liang L., et al. Low expression of DAB2IP contributes to malignant development and poor prognosis in hepatocellular carcinoma. JGastroenterol Hepatol 2012, 27:1117-1125.
-
(2012)
JGastroenterol Hepatol
, vol.27
, pp. 1117-1125
-
-
Zhang, X.1
Li, N.2
Li, X.3
Zhao, W.4
Qiao, Y.5
Liang, L.6
-
136
-
-
38549108547
-
Induction of abnormal proliferation by nonmyelinating schwann cells triggers neurofibroma formation
-
Zheng H., Chang L., Patel N., Yang J., Lowe L., Burns D.K., et al. Induction of abnormal proliferation by nonmyelinating schwann cells triggers neurofibroma formation. Cancer Cell 2008, 13:117-128.
-
(2008)
Cancer Cell
, vol.13
, pp. 117-128
-
-
Zheng, H.1
Chang, L.2
Patel, N.3
Yang, J.4
Lowe, L.5
Burns, D.K.6
-
137
-
-
0037012848
-
Neurofibromas in NF1: schwann cell origin and role of tumor environment
-
Zhu Y., Ghosh P., Charnay P., Burns D.K., Parada L.F. Neurofibromas in NF1: schwann cell origin and role of tumor environment. Science 2002, 296:920-922.
-
(2002)
Science
, vol.296
, pp. 920-922
-
-
Zhu, Y.1
Ghosh, P.2
Charnay, P.3
Burns, D.K.4
Parada, L.F.5
-
138
-
-
23644443053
-
Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma
-
Zhu Y., Guignard F., Zhao D., Liu L., Burns D.K., Mason R.P., et al. Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma. Cancer Cell 2005, 8:119-130.
-
(2005)
Cancer Cell
, vol.8
, pp. 119-130
-
-
Zhu, Y.1
Guignard, F.2
Zhao, D.3
Liu, L.4
Burns, D.K.5
Mason, R.P.6
|