메뉴 건너뛰기




Volumn 12, Issue 5, 2013, Pages 540-545

Overexpression of IQGAP1 in human pancreatic cancer

Author keywords

Immunohistochemistry; IQGAP1; Pancreatic cancer; Tissue microarray

Indexed keywords

IQ MOTIF CONTAINING GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN 1; MESSENGER RNA; PARAFFIN;

EID: 84886290834     PISSN: 14993872     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1499-3872(13)60085-5     Document Type: Article
Times cited : (36)

References (34)
  • 1
    • 77950635816 scopus 로고    scopus 로고
    • Pancreatic cancer: Pathobiology, treatment options, and drug delivery
    • Li J, Wientjes MG, Au JL. Pancreatic cancer: pathobiology, treatment options, and drug delivery. AAPS J 2010;12:223-232.
    • (2010) AAPS J , vol.12 , pp. 223-232
    • Li, J.1    Wientjes, M.G.2    Au, J.L.3
  • 4
    • 84995748195 scopus 로고    scopus 로고
    • The clinical utility of serum CA 19-9 in the diagnosis, prognosis and management of pancreatic adenocarcinoma: An evidence based appraisal
    • Ballehaninna UK, Chamberlain RS. The clinical utility of serum CA 19-9 in the diagnosis, prognosis and management of pancreatic adenocarcinoma: An evidence based appraisal. J Gastrointest Oncol 2012;3:105-119.
    • (2012) J Gastrointest Oncol , vol.3 , pp. 105-119
    • Ballehaninna, U.K.1    Chamberlain, R.S.2
  • 5
    • 0037116623 scopus 로고    scopus 로고
    • Overexpression of pRB in human pancreatic carcinoma cells: Function in chemotherapy-induced apoptosis
    • Plath T, Peters M, Detjen K, Welzel M, von Marschall Z, Radke C, et al. Overexpression of pRB in human pancreatic carcinoma cells: function in chemotherapy-induced apoptosis. J Natl Cancer Inst 2002;94:129-142.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 129-142
    • Plath, T.1    Peters, M.2    Detjen, K.3    Welzel, M.4    von Marschall, Z.5    Radke, C.6
  • 6
    • 0033569824 scopus 로고    scopus 로고
    • K-ras mutations in duodenal aspirate without secretin stimulation for screening of pancreatic and biliary tract carcinoma
    • Watanabe H, Ha A, Hu YX, Ohtsubo K, Yamaguchi Y, Motoo Y, et al. K-ras mutations in duodenal aspirate without secretin stimulation for screening of pancreatic and biliary tract carcinoma. Cancer 1999;86:1441-1448.
    • (1999) Cancer , vol.86 , pp. 1441-1448
    • Watanabe, H.1    Ha, A.2    Hu, Y.X.3    Ohtsubo, K.4    Yamaguchi, Y.5    Motoo, Y.6
  • 7
    • 0032901753 scopus 로고    scopus 로고
    • Detection of mutations of p53 tumor suppressor gene in pancreatic juice and its application to diagnosis of patients with pancreatic cancer: Comparison with K-ras mutation
    • Yamaguchi Y, Watanabe H, Yrdiran S, Ohtsubo K, Motoo Y, Okai T, et al. Detection of mutations of p53 tumor suppressor gene in pancreatic juice and its application to diagnosis of patients with pancreatic cancer: comparison with K-ras mutation. Clin Cancer Res 1999;5:1147-1153.
    • (1999) Clin Cancer Res , vol.5 , pp. 1147-1153
    • Yamaguchi, Y.1    Watanabe, H.2    Yrdiran, S.3    Ohtsubo, K.4    Motoo, Y.5    Okai, T.6
  • 8
    • 0030795157 scopus 로고    scopus 로고
    • Frequent loss of p16 expression and its correlation with clinicopathological parameters in pancreatic carcinoma
    • Hu YX, Watanabe H, Ohtsubo K, Yamaguchi Y, Ha A, Okai T, et al. Frequent loss of p16 expression and its correlation with clinicopathological parameters in pancreatic carcinoma. Clin Cancer Res 1997;3:1473-1477.
    • (1997) Clin Cancer Res , vol.3 , pp. 1473-1477
    • Hu, Y.X.1    Watanabe, H.2    Ohtsubo, K.3    Yamaguchi, Y.4    Ha, A.5    Okai, T.6
  • 9
    • 0037343237 scopus 로고    scopus 로고
    • Overexpression of oncogenic STK15/BTAK/Aurora A kinase in human pancreatic cancer
    • Li D, Zhu J, Firozi PF, Abbruzzese JL, Evans DB, Cleary K, et al. Overexpression of oncogenic STK15/BTAK/Aurora A kinase in human pancreatic cancer. Clin Cancer Res 2003;9: 991-997.
    • (2003) Clin Cancer Res , vol.9 , pp. 991-997
    • Li, D.1    Zhu, J.2    Firozi, P.F.3    Abbruzzese, J.L.4    Evans, D.B.5    Cleary, K.6
  • 11
    • 0030969478 scopus 로고    scopus 로고
    • Overexpression of cyclin D1 in human pancreatic carcinoma is associated with poor prognosis
    • Gansauge S, Gansauge F, Ramadani M, Stobbe H, Rau B, Harada N, et al. Overexpression of cyclin D1 in human pancreatic carcinoma is associated with poor prognosis. Cancer Res 1997;57:1634-1637.
    • (1997) Cancer Res , vol.57 , pp. 1634-1637
    • Gansauge, S.1    Gansauge, F.2    Ramadani, M.3    Stobbe, H.4    Rau, B.5    Harada, N.6
  • 12
    • 0026020115 scopus 로고
    • Transforming growth factor alpha and epidermal growth factor in human pancreatic cancer
    • Barton CM, Hall PA, Hughes CM, Gullick WJ, Lemoine NR. Transforming growth factor alpha and epidermal growth factor in human pancreatic cancer. J Pathol 1991;163:111-116.
    • (1991) J Pathol , vol.163 , pp. 111-116
    • Barton, C.M.1    Hall, P.A.2    Hughes, C.M.3    Gullick, W.J.4    Lemoine, N.R.5
  • 13
    • 33646726750 scopus 로고    scopus 로고
    • IQGAP1 in cellular signaling: Bridging the GAP
    • Brown MD, Sacks DB. IQGAP1 in cellular signaling: bridging the GAP. Trends Cell Biol 2006;16:242-249.
    • (2006) Trends Cell Biol , vol.16 , pp. 242-249
    • Brown, M.D.1    Sacks, D.B.2
  • 14
    • 67349198476 scopus 로고    scopus 로고
    • IQGAPs in cancer: A family of scaffold proteins underlying tumorigenesis
    • White CD, Brown MD, Sacks DB. IQGAPs in cancer: a family of scaffold proteins underlying tumorigenesis. FEBS Lett 2009;583:1817-1824.
    • (2009) FEBS Lett , vol.583 , pp. 1817-1824
    • White, C.D.1    Brown, M.D.2    Sacks, D.B.3
  • 15
    • 0043093686 scopus 로고    scopus 로고
    • IQGAP proteins are integral components of cytoskeletal regulation
    • Briggs MW, Sacks DB. IQGAP proteins are integral components of cytoskeletal regulation. EMBO Rep 2003;4: 571-574.
    • (2003) EMBO Rep , vol.4 , pp. 571-574
    • Briggs, M.W.1    Sacks, D.B.2
  • 16
    • 77955833744 scopus 로고    scopus 로고
    • IQGAP1 is overexpressed in hepatocellular carcinoma and promotes cell proliferation by Akt activation
    • Chen F, Zhu HH, Zhou LF, Wu SS, Wang J, Chen Z. IQGAP1 is overexpressed in hepatocellular carcinoma and promotes cell proliferation by Akt activation. Exp Mol Med 2010;42:477-483.
    • (2010) Exp Mol Med , vol.42 , pp. 477-483
    • Chen, F.1    Zhu, H.H.2    Zhou, L.F.3    Wu, S.S.4    Wang, J.5    Chen, Z.6
  • 17
    • 77953395353 scopus 로고    scopus 로고
    • An emerging role for IQGAP1 in regulating protein traffic
    • Osman M. An emerging role for IQGAP1 in regulating protein traffic. ScientificWorldJournal 2010;10:944-953.
    • (2010) Scientific World Journal , vol.10 , pp. 944-953
    • Osman, M.1
  • 18
    • 0037039718 scopus 로고    scopus 로고
    • Immunohisto-chemical analysis of IQGAP1 expression in human colorectal carcinomas: Its overexpression in carcinomas and association with invasion fronts
    • Nabeshima K, Shimao Y, Inoue T, Koono M. Immunohisto-chemical analysis of IQGAP1 expression in human colorectal carcinomas: its overexpression in carcinomas and association with invasion fronts. Cancer Lett 2002;176:101-109.
    • (2002) Cancer Lett , vol.176 , pp. 101-109
    • Nabeshima, K.1    Shimao, Y.2    Inoue, T.3    Koono, M.4
  • 19
    • 77951247324 scopus 로고    scopus 로고
    • Overexpression of IQGAP1 in advanced colorectal cancer correlates with poor prognosis-critical role in tumor invasion
    • Hayashi H, Nabeshima K, Aoki M, Hamasaki M, Enatsu S, Yamauchi Y, et al. Overexpression of IQGAP1 in advanced colorectal cancer correlates with poor prognosis-critical role in tumor invasion. Int J Cancer 2010;126:2563-2574.
    • (2010) Int J Cancer , vol.126 , pp. 2563-2574
    • Hayashi, H.1    Nabeshima, K.2    Aoki, M.3    Hamasaki, M.4    Enatsu, S.5    Yamauchi, Y.6
  • 20
    • 0035869652 scopus 로고    scopus 로고
    • Localization of IQGAP1 is inversely correlated with intercellular adhesion mediated by e-cadherin in gastric cancers
    • Takemoto H, Doki Y, Shiozaki H, Imamura H, Utsunomiya T, Miyata H, et al. Localization of IQGAP1 is inversely correlated with intercellular adhesion mediated by e-cadherin in gastric cancers. Int J Cancer 2001;91:783-788.
    • (2001) Int J Cancer , vol.91 , pp. 783-788
    • Takemoto, H.1    Doki, Y.2    Shiozaki, H.3    Imamura, H.4    Utsunomiya, T.5    Miyata, H.6
  • 21
    • 42549116142 scopus 로고    scopus 로고
    • Combined analysis of Rac1, IQGAP1, Tiam1 and E-cadherin expression in gastric cancer
    • Walch A, Seidl S, Hermannstädter C, Rauser S, Deplazes J, Langer R, et al. Combined analysis of Rac1, IQGAP1, Tiam1 and E-cadherin expression in gastric cancer. Mod Pathol 2008;21:544-552.
    • (2008) Mod Pathol , vol.21 , pp. 544-552
    • Walch, A.1    Seidl, S.2    Hermannstädter, C.3    Rauser, S.4    Deplazes, J.5    Langer, R.6
  • 22
    • 33749251431 scopus 로고    scopus 로고
    • Overexpression and diffuse expression pattern of IQGAP1 at invasion fronts are independent prognostic parameters in ovarian carcinomas
    • Dong P, Nabeshima K, Nishimura N, Kawakami T, Hachisuga T, Kawarabayashi T, et al. Overexpression and diffuse expression pattern of IQGAP1 at invasion fronts are independent prognostic parameters in ovarian carcinomas. Cancer Lett 2006;243:120-127.
    • (2006) Cancer Lett , vol.243 , pp. 120-127
    • Dong, P.1    Nabeshima, K.2    Nishimura, N.3    Kawakami, T.4    Hachisuga, T.5    Kawarabayashi, T.6
  • 24
    • 38149036613 scopus 로고    scopus 로고
    • IQGAP1 stimulates proliferation and enhances tumorigenesis of human breast epithelial cells
    • Jadeski L, Mataraza JM, Jeong HW, Li Z, Sacks DB. IQGAP1 stimulates proliferation and enhances tumorigenesis of human breast epithelial cells. J Biol Chem 2008;283:1008-1017.
    • (2008) J Biol Chem , vol.283 , pp. 1008-1017
    • Jadeski, L.1    Mataraza, J.M.2    Jeong, H.W.3    Li, Z.4    Sacks, D.B.5
  • 27
    • 0032493903 scopus 로고    scopus 로고
    • Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-cadherin-mediated cell-cell adhesion
    • Kuroda S, Fukata M, Nakagawa M, Fujii K, Nakamura T, Ookubo T, et al. Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-cadherin-mediated cell-cell adhesion. Science 1998;281:832-835.
    • (1998) Science , vol.281 , pp. 832-835
    • Kuroda, S.1    Fukata, M.2    Nakagawa, M.3    Fujii, K.4    Nakamura, T.5    Ookubo, T.6
  • 28
    • 0033543551 scopus 로고    scopus 로고
    • Cdc42 and Rac1 regulate the interaction of IQGAP1 with beta-catenin
    • Fukata M, Kuroda S, Nakagawa M, Kawajiri A, Itoh N, Shoji I, et al. Cdc42 and Rac1 regulate the interaction of IQGAP1 with beta-catenin. J Biol Chem 1999;274:26044-26050.
    • (1999) J Biol Chem , vol.274 , pp. 26044-26050
    • Fukata, M.1    Kuroda, S.2    Nakagawa, M.3    Kawajiri, A.4    Itoh, N.5    Shoji, I.6
  • 29
    • 0036510761 scopus 로고    scopus 로고
    • IQGAP1-mediated stimulation of transcriptional co-activation by beta-catenin is modulated by calmodulin
    • Briggs MW, Li Z, Sacks DB. IQGAP1-mediated stimulation of transcriptional co-activation by beta-catenin is modulated by calmodulin. J Biol Chem 2002;277:7453-7465.
    • (2002) J Biol Chem , vol.277 , pp. 7453-7465
    • Briggs, M.W.1    Li, Z.2    Sacks, D.B.3
  • 31
    • 24344491858 scopus 로고    scopus 로고
    • IQGAP1 is a scaffold for mitogen-activated protein kinase signaling
    • Roy M, Li Z, Sacks DB. IQGAP1 is a scaffold for mitogen-activated protein kinase signaling. Mol Cell Biol 2005;25: 7940-7952.
    • (2005) Mol Cell Biol , vol.25 , pp. 7940-7952
    • Roy, M.1    Li, Z.2    Sacks, D.B.3
  • 32
    • 2342424547 scopus 로고    scopus 로고
    • IQGAP1 binds ERK2 and modulates its activity
    • Roy M, Li Z, Sacks DB. IQGAP1 binds ERK2 and modulates its activity. J Biol Chem 2004;279:17329-17337.
    • (2004) J Biol Chem , vol.279 , pp. 17329-17337
    • Roy, M.1    Li, Z.2    Sacks, D.B.3
  • 34
    • 10644281068 scopus 로고    scopus 로고
    • Interaction with IQGAP1 links APC to Rac1, Cdc42, and actin filaments during cell polarization and migration
    • Watanabe T, Wang S, Noritake J, Sato K, Fukata M, Takefuji M, et al. Interaction with IQGAP1 links APC to Rac1, Cdc42, and actin filaments during cell polarization and migration. Dev Cell 2004;7:871-883.
    • (2004) Dev Cell , vol.7 , pp. 871-883
    • Watanabe, T.1    Wang, S.2    Noritake, J.3    Sato, K.4    Fukata, M.5    Takefuji, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.