메뉴 건너뛰기




Volumn 155, Issue 6, 1999, Pages 1855-1860

Deletions of the INK4A gene occur in malignant peripheral nerve sheath tumors but not in neurofibromas

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CANCER GENETICS; CLINICAL ARTICLE; CONTROLLED STUDY; GENE AMPLIFICATION; GENE DELETION; GENE MUTATION; HUMAN; HUMAN TISSUE; NERVE SHEATH TUMOR; NEUROFIBROMA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SINGLE STRAND CONFORMATION POLYMORPHISM; SOUTHERN BLOTTING;

EID: 0032763415     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)65504-6     Document Type: Article
Times cited : (140)

References (37)
  • 1
    • 0027769876 scopus 로고
    • A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK4
    • Serrano M, Hannon GJ, Beach D: A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK4. Nature 1993, 366:704-707
    • (1993) Nature , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3
  • 2
    • 0028168242 scopus 로고
    • INK4B is a potential effector of tgfb-induced cell cycle arrest
    • INK4B is a potential effector of TGFb-induced cell cycle arrest. Nature 1994, 371:257-261
    • (1994) Nature , vol.371 , pp. 257-261
    • Hannon, G.J.1    Beach, D.2
  • 6
    • 0029587551 scopus 로고
    • Alternative reading frames of the INK4A tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
    • Quelle DE, Zindy F, Ashmun RA, Sherr CJ: Alternative reading frames of the INK4A tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest. Cell 1995, 83:993-1000
    • (1995) Cell , vol.83 , pp. 993-1000
    • Quelle, D.E.1    Zindy, F.2    Ashmun, R.A.3    Sherr, C.J.4
  • 8
    • 0032549711 scopus 로고    scopus 로고
    • ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4A locus deletion impairs both the Rb and p53 tumor suppressor pathways
    • Zhang Y, Xiong Y, Yarbrough WG: ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4A locus deletion impairs both the Rb and p53 tumor suppressor pathways. Cell 1998, 92:725-734
    • (1998) Cell , vol.92 , pp. 725-734
    • Zhang, Y.1    Xiong, Y.2    Yarbrough, W.G.3
  • 9
    • 0028275733 scopus 로고
    • Deletions of cyclin-dependent kinase-4 inhibitor gene in multiple human cancers
    • Nobori T, Miura K, Wu DJ, Lois A, Takabayashi K, Carson DA: Deletions of cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature 1994, 368:753-756
    • (1994) Nature , vol.368 , pp. 753-756
    • Nobori, T.1    Miura, K.2    Wu, D.J.3    Lois, A.4    Takabayashi, K.5    Carson, D.A.6
  • 11
    • 0029901708 scopus 로고    scopus 로고
    • High frequency of aberrant p16(INK4A) expression in human breast cancer
    • Geradts J, Wilson PA: High frequency of aberrant p16(INK4A) expression in human breast cancer. Am J Pathol 1996, 149:15-20
    • (1996) Am J Pathol , vol.149 , pp. 15-20
    • Geradts, J.1    Wilson, P.A.2
  • 12
    • 0030783770 scopus 로고    scopus 로고
    • Among genes involved in RB dependent cell cycle regulatory cascade, the p16 tumor suppressor gene is frequently lost in the Ewing family of tumors
    • Kovar H, Jug G, Aryee DN, Zoubek A, Ambros P, Gryber B, Windhager R, Gadner H: Among genes involved in RB dependent cell cycle regulatory cascade, the p16 tumor suppressor gene is frequently lost in the Ewing family of tumors. Oncogene 1997, 15: 2225-2232
    • (1997) Oncogene , vol.15 , pp. 2225-2232
    • Kovar, H.1    Jug, G.2    Aryee, D.N.3    Zoubek, A.4    Ambros, P.5    Gryber, B.6    Windhager, R.7    Gadner, H.8
  • 13
    • 0030896090 scopus 로고    scopus 로고
    • Loss of heterozygosity on chromosome 9q21 (p16 gene) uncommon in soft tissue sarcomas
    • Schneider-Stock R, Radig K, Roessner A: Loss of heterozygosity on chromosome 9q21 (p16 gene) uncommon in soft tissue sarcomas. Mol Carcinog 1997, 18:63-65
    • (1997) Mol Carcinog , vol.18 , pp. 63-65
    • Schneider-Stock, R.1    Radig, K.2    Roessner, A.3
  • 16
    • 0030467624 scopus 로고    scopus 로고
    • The p16-cyclin D/Cdk4-pRb pathway as a functional unit frequently altered in melanoma pathogenesis
    • Bartkova J, Lukas J, Guldberg P, Alsner J, Kirkin AF, Zeuthen J, Bartek J: The p16-cyclin D/Cdk4-pRb pathway as a functional unit frequently altered in melanoma pathogenesis. Cancer Res 1996, 56:5475-5483
    • (1996) Cancer Res , vol.56 , pp. 5475-5483
    • Bartkova, J.1    Lukas, J.2    Guldberg, P.3    Alsner, J.4    Kirkin, A.F.5    Zeuthen, J.6    Bartek, J.7
  • 18
    • 0028652269 scopus 로고
    • CDKN2 (p16/ MTS1) gene deletion or CDK4 amplification occurs in the majority of glioblastomas
    • Schmidt EE, Ichimura K, Reinfenberger G, Collins P: CDKN2 (p16/ MTS1) gene deletion or CDK4 amplification occurs in the majority of glioblastomas. Cancer Res 1994, 54:6321-6324
    • (1994) Cancer Res , vol.54 , pp. 6321-6324
    • Schmidt, E.E.1    Ichimura, K.2    Reinfenberger, G.3    Collins, P.4
  • 19
    • 0028897307 scopus 로고
    • Homozygous deletions of the multiple tumor suppessor gene 1 in the progression of human astrocytomas
    • Walker DG, Duan W, Popovic EA, Kaye AH, Tomlinson FH, Lavin M: Homozygous deletions of the multiple tumor suppessor gene 1 in the progression of human astrocytomas. Cancer Res 1995, 55:20-23
    • (1995) Cancer Res , vol.55 , pp. 20-23
    • Walker, D.G.1    Duan, W.2    Popovic, E.A.3    Kaye, A.H.4    Tomlinson, F.H.5    Lavin, M.6
  • 24
    • 0025050425 scopus 로고
    • Malignant peripheral nerve sheath tumors of the buttock and lower extremity: A study of 43 cases
    • Hruban RH, Shiu MH, Senie RT, Woodruff JM: Malignant peripheral nerve sheath tumors of the buttock and lower extremity: a study of 43 cases. Cancer 1990, 66:1253-1265
    • (1990) Cancer , vol.66 , pp. 1253-1265
    • Hruban, R.H.1    Shiu, M.H.2    Senie, R.T.3    Woodruff, J.M.4
  • 25
    • 0032102426 scopus 로고    scopus 로고
    • Subdiaphragmatic and intrathoracic paraspinal malignant peripheral nerve sheath tumor: A clinicopathologic study of 25 patients and 26 tumors
    • Kourea HP, Bilsky MH, Leung DH, Lewis JJ, Woodruff JM: Subdiaphragmatic and intrathoracic paraspinal malignant peripheral nerve sheath tumor: a clinicopathologic study of 25 patients and 26 tumors. Cancer 1998, 82:2191-2203
    • (1998) Cancer , vol.82 , pp. 2191-2203
    • Kourea, H.P.1    Bilsky, M.H.2    Leung, D.H.3    Lewis, J.J.4    Woodruff, J.M.5
  • 28
    • 0029131833 scopus 로고
    • Immunohistochemical and molecular analysis of p53, MDM2, proliferating cell nuclear antigen and Ki67 in benign and malignant nerve sheath tumors
    • Kindblom LG, Ahlden M, Meis-Kindblom JM, Stenman G: Immunohistochemical and molecular analysis of p53, MDM2, proliferating cell nuclear antigen and Ki67 in benign and malignant nerve sheath tumors. Virchows Arch 1995, 427:19-26
    • (1995) Virchows Arch , vol.427 , pp. 19-26
    • Kindblom, L.G.1    Ahlden, M.2    Meis-Kindblom, J.M.3    Stenman, G.4
  • 29
    • 0029781715 scopus 로고    scopus 로고
    • p53 expression in neurofibroma, and malignant peripheral nerve sheath tumor: An immunohistochemical study of sporadic, and NF1-associated tumors
    • Halling KC, Scheithauer BW, Halling A, Nascimento AG, Ziesmer SC, Roche PC, Wollan PC: p53 expression in neurofibroma, and malignant peripheral nerve sheath tumor: an immunohistochemical study of sporadic, and NF1-associated tumors. Am J Clin Pathol 1996, 106:282-288
    • (1996) Am J Clin Pathol , vol.106 , pp. 282-288
    • Halling, K.C.1    Scheithauer, B.W.2    Halling, A.3    Nascimento, A.G.4    Ziesmer, S.C.5    Roche, P.C.6    Wollan, P.C.7
  • 31
    • 0024756969 scopus 로고
    • Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction
    • Orita M, Suzuki Y, Sekiya T, Hayashi K: Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction. Genomics 1989, 5:874-879
    • (1989) Genomics , vol.5 , pp. 874-879
    • Orita, M.1    Suzuki, Y.2    Sekiya, T.3    Hayashi, K.4
  • 34
    • 0029884472 scopus 로고    scopus 로고
    • Infrequent alterations of the p15, p16, CDK4 and cyclin d1 genes in non-astrocytic human brain tumors
    • Sato K, Schauble B, Kleihues P, Ohgaki H: Infrequent alterations of the p15, p16, CDK4 and cyclin D1 genes in non-astrocytic human brain tumors. Int J Cancer 1996, 66:305-308
    • (1996) Int J Cancer , vol.66 , pp. 305-308
    • Sato, K.1    Schauble, B.2    Kleihues, P.3    Ohgaki, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.