Potential prognostic value of mitogen-activated protein kinase activity for disease-free survival of primary breast cancer patients

International Journal of Cancer

Volumn 89, Issue 4, 2000, Pages 384-388

  Mueller, Heinz ^a,b   Flury, Nathalie ^a   Eppenberger Castori, Serenella ^a   Kueng, Willy ^a   David, Françoise ^a   Eppenberger, Urs ^a  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

^b UNIVERSITY WOMEN S HOSPITAL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE;

ARTICLE; BREAST CANCER; CANCER RECURRENCE; CANCER SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; HUMAN; HUMAN TISSUE; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROGNOSIS;

BREAST; BREAST NEOPLASMS; DISEASE-FREE SURVIVAL; ENZYME ACTIVATION; FEMALE; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; NEOPLASM RECURRENCE, LOCAL; RETROSPECTIVE STUDIES; RISK FACTORS;

EID: 0034691562     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0215(20000720)89:4<384::AID-IJC11>3.0.CO;2-R     Document Type: Article

References (24)

1. ANDERSON, N.G., MALLER, J.L., TONKS, N.K. and STURGILL, T.W., Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase. Nature (Lond.), 343, 651-651 (1990).
2. CASTORIA, G., BARONE, M.V., DI DOMENICO, M., BILANCIO, A., AMETRANO, D., MIGLIACCIO, A. and AURICCHIO, F., Non-transcriptional action of oestradiol and progestin triggers DNA synthesis. EMBO J., 18, 2500-2510 (1999).
3. CLARK-LEWIS, I., SANGHERA, J.S. and PELECH, S.L., Definition of a consensus sequence for peptide substrate recognition by p44mpk, the meiosis-activated myelin basic protein kinase. J. biol. Chem., 266, 15180-15184 (1991).
4. COBB, H.H., BOULTON, T.G. and ROBBINS, D.J., Extracellular signal-regulated kinases: ERKs in progress. Cell Regul., 2, 965-978 (1991a).
5. COBB, M.H. and GOLDSMITH, E.J., How MAP kinases are regulated. J. biol. Chem., 270, 14843-14846 (1995).
6. COBB, M.H., ROBBINS, D.J. and BOULTON, T.G., ErKs, extracellular signal-regulated MAP-2 kinases. Curr. Opin. cell Biol., 3, 1025-1032 (1991b).
7. COWLEY, S., PATERSON, H., KEMP, P. and MARSHALL, C.J., Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell, 77, 841-852 (1994).
8. EPPENBERGER, U. and 12 OTHERS, Markers of tumor angiogenesis and proteolysis independently define high- and low-risk subsets of node-negative breast cancer patients. J. clin. Oncol., 16, 3129-3136 (1998).
9. FLURY, N., EPPENBERGER, U. and MUELLER, H., Tumor necrosis factor alpha modulates mitogen-activated protein kinase activity of epidermal growth factor-stimulated MCF-7 breast cancer cells. Europ. J. Biochem., 249, 421-426 (1997).
10. FORCE, T. and BONVENTRE, J.V., Growth factors and mitogen-activated protein kinases. Hypertension, 31, 152-161 (1998).
11. GUPTA, S.K., GALLEGO, C., JOHNSON, G.L. and HEASLEY, L.E., MAP kinase is constitutively activated in gip2 and src transformed rat la fibroblasts. J. Biol. Chem., 267, 7987-7990 (1992).
12. JANES, P.W., DALY, R.J., DEFAZIO, A. and SUTHERLAND, R.L., Activation of the Ras signalling pathway in human breast cancer cells overexpressing erbB-2. Oncogene, 9, 3601-3608 (1994).
13. KAULSA Y. K.K., MERTANI, H.C., TORNELL, J., MOREL, G., LEE, K.O. and LOBIE, P.E., Autocrine stimulation of human mammary carcinoma cell proliferation by human growth hormone. Exp. cell Res., 250, 35-50 (1999).
14. KENNEY, N.J., SAEKI, T., GOTTARDIS, M., KIM, N., GARCIA-MORALES, P., MARTIN, M.B., NORMANNO, N., CIARDIELLO, F., DAY, A., CUTLER, M.L. and SALOMON, D.S., Expression of transforming growth factor alpha antisense mRNA inhibits the estrogen-induced production of TGF alpha and estrogen-induced proliferation of estrogen-responsive human breast cancer cells. J. cell Physiol., 156, 497-514 (1993).
15. KIM-SCHULZE, S., LOWE, W.L. JR. and SCHNAPER, H.W., Estrogen stimulates delayed mitogen-activated protein kinase activity in human endothelial cells via an autocrine loop that involves basic fibroblast growth factor. Circulation, 98, 413-421 (1998).
16. MANSOUR, S.J., MATTEN, W.T., HERMANN, A.S., CANDIA, J.M., RONG, S., FUKASAWA, K., VANDE WOUDE, G.F. and AHN, N.G., Transformation of mammalian cells by constitutively active MAP kinase kinase. Science, 265, 966-970 (1994).
17. PELECH, S.L. and SANGHERA, J.S., MAP kinases: charting the regulatory pathways. Science, 257, 1355-1356 (1992).
18. RAZANDI, M., PEDRAM, A., GREENE, G.L. and LEVIN, E.R., Cell membrane and nuclear estrogen receptors (ERs) originate from a single transcript: studies of ERalpha and ERbeta expressed in Chinese hamster ovary cells. Mol. Endocrinol., 13, 307-319 (1999).
19. REDDY, K.B., YEE, D., HILSENBECK, S.G., COFFEY, R.J. and OSBORNE, C.K., Inhibition of estrogen-induced breast cancer cell proliferation by reduction in autocrine transforming growth factor alpha expression. Cell Growth Differentiation, 5, 1275-1282 (1994).
20. SCHLAEPPI, J.M., EPPENBERGER, U., MARTINY-BARON, G. and KUNG, W., Chemiluminescence immunoassay for vascular endothelial growth factor (vascular permeability factor) in tumor-tissue homogenates. Clin. Chem., 42, 1777-1784 (1996).
21. SEBOLT-LEOPOLD, J.S., DUDLEY, D.T., HERRERA, R., VAN BECELAERE, K., WILAND, A., GOWAN, R.C., TECLE, H., BARRETT, S.D., BRIDGES, A., PRZYBRANOWSKI, S., LEOPOLD, W.R. and SALTIEL, A.R., Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo [see comments]. Nature (Med.), 5, 810-816 (1999).
22. SEGER, R. and KREBS, E.G., The MAPK signaling cascade. FASEB J., 9, 726-735 (1995).
23. SIVARAMAN, V.S., WANG, H., NUOVO, G.J. and MALBON, C.C., Hyperexpression of mitogen-activated protein kinase in human breast cancer. J. clin. Invest., 99, 1478-1483 (1997).
24. VERHEIJ, M. and 12 OTHERS, Requirement for ceramide-initiated SAPK/ JNK signalling in stress-induced apoptosis. Nature (Lond.), 380, 75-79 1996.