IQGAP2 inactivation through aberrant promoter methylation and promotion of invasion in gastric cancer cells

International Journal of Cancer

Volumn 122, Issue 5, 2008, Pages 1040-1046

  Jin, Shun Hua ^a   Akiyama, Yoshimitsu ^a   Fukamachi, Hiroshi ^a   Yanagihara, Kazuyoshi ^b   Akashi, Takumi ^a   Yuasa, Yasuhito ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

Gastric cancer; Invasion; IQGAP2; Methylation; Prognosis

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; GENE PRODUCT; IQ MOTIF CONTAINING GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN 1; MESSENGER RNA; PROTEIN IQGAP2; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; IQGAP2 PROTEIN, HUMAN;

ADULT; ARTICLE; CANCER CELL CULTURE; CANCER INVASION; CANCER TISSUE; CELL ADHESION; CELL MIGRATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE; GENE INACTIVATION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IQGAP2 GENE; MALE; METASTASIS; METHYLATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FAMILY; SIGNAL TRANSDUCTION; STOMACH CANCER; STOMACH CARCINOGENESIS; DNA METHYLATION; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; KAPLAN MEIER METHOD; METABOLISM; MIDDLE AGED; MORTALITY; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH TUMOR; TUMOR CELL LINE;

CELL LINE, TUMOR; DNA METHYLATION; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HUMANS; IMMUNOHISTOCHEMISTRY; KAPLAN-MEIERS ESTIMATE; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; PROMOTER REGIONS (GENETICS); RAS GTPASE-ACTIVATING PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STOMACH NEOPLASMS; TRANSFECTION;

EID: 38749103163     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.23181     Document Type: Article

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