-
1
-
-
0345211578
-
Identification of human GC-box-binding zinc finger protein, a new Kruppel-like zinc finger protein, by the yeast one-hybrid screening with a GC-rich target sequence
-
1:CAS:528:DyaK1MXkt1ags7s%3D 10405178 10.1016/S0014-5793(99)00754-1
-
Lisowsky T, Polosa PL, Sagliano A, Roberti M, Gadaleta MN, Cantatore P (1999) Identification of human GC-box-binding zinc finger protein, a new Kruppel-like zinc finger protein, by the yeast one-hybrid screening with a GC-rich target sequence. FEBS Lett 453:369-374
-
(1999)
FEBS Lett
, vol.453
, pp. 369-374
-
-
Lisowsky, T.1
Polosa, P.L.2
Sagliano, A.3
Roberti, M.4
Gadaleta, M.N.5
Cantatore, P.6
-
2
-
-
0033584462
-
ZBP-99 defines a conserved family of transcription factors and regulates ornithine decarboxylase gene expression
-
1:CAS:528:DyaK1MXltFShu7o%3D 10448078 10.1006/bbrc.1999.1180
-
Law DJ, Du M, Law GL, Merchant JL (1999) ZBP-99 defines a conserved family of transcription factors and regulates ornithine decarboxylase gene expression. Biochem Biophys Res Commun 262:113-120
-
(1999)
Biochem Biophys Res Commun
, vol.262
, pp. 113-120
-
-
Law, D.J.1
Du, M.2
Law, G.L.3
Merchant, J.L.4
-
3
-
-
56249102803
-
The transcription factor Zfp281 controls embryonic stem cell pluripotency by direct activation and repression of target genes
-
1:CAS:528:DC%2BD1MXmsF2i 18757296 10.1634/stemcells.2008-0443
-
Wang ZX, Teh CH, Chan CM, Chu C, Rossbach M, Kunarso G, Allapitchay TB, Wong KY, Stanton LW (2008) The transcription factor Zfp281 controls embryonic stem cell pluripotency by direct activation and repression of target genes. Stem Cells 26:2791-2799
-
(2008)
Stem Cells
, vol.26
, pp. 2791-2799
-
-
Wang, Z.X.1
Teh, C.H.2
Chan, C.M.3
Chu, C.4
Rossbach, M.5
Kunarso, G.6
Allapitchay, T.B.7
Wong, K.Y.8
Stanton, L.W.9
-
4
-
-
84866854032
-
A genome-wide signature of glucocorticoid receptor binding in neuronal PC12 cells
-
1:CAS:528:DC%2BC3sXhvVOqsLw%3D 3519639 23031785 10.1186/1471-2202-13-118
-
Polman JA, Welten JE, Bosch DS, de Jonge RT, Balog J, van der Maarel SM, de Kloet ER, Datson NA (2012) A genome-wide signature of glucocorticoid receptor binding in neuronal PC12 cells. BMC Neurosci 13:118
-
(2012)
BMC Neurosci
, vol.13
, pp. 118
-
-
Polman, J.A.1
Welten, J.E.2
Bosch, D.S.3
De Jonge, R.T.4
Balog, J.5
Van Der Maarel, S.M.6
De Kloet, E.R.7
Datson, N.A.8
-
5
-
-
0034960978
-
ZBP-89 promotes growth arrest through stabilization of p53
-
1:CAS:528:DC%2BD3MXks1Gju7o%3D 87140 11416144 10.1128/MCB.21.14.4670- 4683.2001
-
Bai L, Merchant JL (2001) ZBP-89 promotes growth arrest through stabilization of p53. Mol Cell Biol 21:4670-4683
-
(2001)
Mol Cell Biol
, vol.21
, pp. 4670-4683
-
-
Bai, L.1
Merchant, J.L.2
-
6
-
-
2942736803
-
ZBP-89-induced apoptosis is p53-independent and requires JNK
-
1:CAS:528:DC%2BD2cXktVGjtrc%3D 14963412
-
Bai L, Yoon SO, King PD, Merchant JL (2004) ZBP-89-induced apoptosis is p53-independent and requires JNK. Cell Death Differ 11:663-673
-
(2004)
Cell Death Differ
, vol.11
, pp. 663-673
-
-
Bai, L.1
Yoon, S.O.2
King, P.D.3
Merchant, J.L.4
-
7
-
-
33750357137
-
The transcription factor ZBP-89 controls generation of the hematopoietic lineage in zebrafish and mouse embryonic stem cells
-
1:CAS:528:DC%2BD28XhtFels73F 16914492 10.1242/dev.02540
-
Li X, Xiong JW, Shelley CS, Park H, Arnaout MA (2006) The transcription factor ZBP-89 controls generation of the hematopoietic lineage in zebrafish and mouse embryonic stem cells. Development 133:3641-3650
-
(2006)
Development
, vol.133
, pp. 3641-3650
-
-
Li, X.1
Xiong, J.W.2
Shelley, C.S.3
Park, H.4
Arnaout, M.A.5
-
8
-
-
33749541089
-
Intestinal overexpression of ZNF148 suppresses ApcMin/+neoplasia
-
1:CAS:528:DC%2BD28XhtVKjtbzO 17019648 10.1007/s00335-006-0052-4
-
Law DJ, Labut EM, Merchant JL (2006) Intestinal overexpression of ZNF148 suppresses ApcMin/+neoplasia. Mamm Genome 17:999-1004
-
(2006)
Mamm Genome
, vol.17
, pp. 999-1004
-
-
Law, D.J.1
Labut, E.M.2
Merchant, J.L.3
-
9
-
-
0242577787
-
The nuclear abundance of transcription factors Sp1 and Sp3 depends on biotin in Jurkat cells
-
1:CAS:528:DC%2BD3sXovFKgsr4%3D 14608051
-
Griffin JB, Rodriguez-Melendez R, Zempleni J (2003) The nuclear abundance of transcription factors Sp1 and Sp3 depends on biotin in Jurkat cells. J Nutr 133:3409-3415
-
(2003)
J Nutr
, vol.133
, pp. 3409-3415
-
-
Griffin, J.B.1
Rodriguez-Melendez, R.2
Zempleni, J.3
-
10
-
-
0035945263
-
Selected base sequence outside the target binding site of zinc finger protein Sp1
-
1:CAS:528:DC%2BD38XmslWitg%3D%3D 97581 11812820 10.1093/nar/29.24.4920
-
Nagaoka M, Shiraishi Y, Sugiura Y (2001) Selected base sequence outside the target binding site of zinc finger protein Sp1. Nucleic Acids Res 29:4920-4929
-
(2001)
Nucleic Acids Res
, vol.29
, pp. 4920-4929
-
-
Nagaoka, M.1
Shiraishi, Y.2
Sugiura, Y.3
-
11
-
-
0034929708
-
Sp1 and kruppel-like factor family of transcription factors in cell growth regulation and cancer
-
1:CAS:528:DC%2BD3MXltVKmsbc%3D 11424081 10.1002/jcp.1111
-
Black AR, Black JD, Azizkhan-Clifford J (2001) Sp1 and kruppel-like factor family of transcription factors in cell growth regulation and cancer. J Cell Physiol 188:143-160
-
(2001)
J Cell Physiol
, vol.188
, pp. 143-160
-
-
Black, A.R.1
Black, J.D.2
Azizkhan-Clifford, J.3
-
12
-
-
58349101326
-
Genome-wide promoter analysis of the SOX4 transcriptional network in prostate cancer cells
-
1:CAS:528:DC%2BD1MXltFSnsg%3D%3D 2629396 19147588 10.1158/0008-5472.CAN- 08-3415
-
Scharer CD, McCabe CD, Ali-Seyed M, Berger MF, Bulyk ML, Moreno CS (2009) Genome-wide promoter analysis of the SOX4 transcriptional network in prostate cancer cells. Cancer Res 69:709-717
-
(2009)
Cancer Res
, vol.69
, pp. 709-717
-
-
Scharer, C.D.1
McCabe, C.D.2
Ali-Seyed, M.3
Berger, M.F.4
Bulyk, M.L.5
Moreno, C.S.6
-
13
-
-
84878983107
-
Sox4 is a master regulator of epithelial-mesenchymal transition by controlling Ezh2 expression and epigenetic reprogramming
-
1:CAS:528:DC%2BC3sXptFKmt7s%3D 23764001 10.1016/j.ccr.2013.04.020
-
Tiwari N, Tiwari VK, Waldmeier L, Balwierz PJ, Arnold P, Pachkov M, Meyer-Schaller N, Schubeler D, van Nimwegen E, Christofori G (2013) Sox4 is a master regulator of epithelial-mesenchymal transition by controlling Ezh2 expression and epigenetic reprogramming. Cancer Cell 23:768-783
-
(2013)
Cancer Cell
, vol.23
, pp. 768-783
-
-
Tiwari, N.1
Tiwari, V.K.2
Waldmeier, L.3
Balwierz, P.J.4
Arnold, P.5
Pachkov, M.6
Meyer-Schaller, N.7
Schubeler, D.8
Van Nimwegen, E.9
Christofori, G.10
-
14
-
-
84865767219
-
SOX4 induces epithelial-mesenchymal transition and contributes to breast cancer progression
-
1:CAS:528:DC%2BC38Xht1ygurnM 22787120 10.1158/0008-5472.CAN-12-1045
-
Zhang J, Liang Q, Lei Y, Yao M, Li L, Gao X, Feng J, Zhang Y, Gao H, Liu DX et al (2012) SOX4 induces epithelial-mesenchymal transition and contributes to breast cancer progression. Cancer Res 72:4597-4608
-
(2012)
Cancer Res
, vol.72
, pp. 4597-4608
-
-
Zhang, J.1
Liang, Q.2
Lei, Y.3
Yao, M.4
Li, L.5
Gao, X.6
Feng, J.7
Zhang, Y.8
Gao, H.9
Liu, D.X.10
-
15
-
-
34249947699
-
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
-
1:CAS:528:DC%2BD2sXls1Kit7o%3D 17525332 10.1126/science.1140321
-
Matsuoka S, Ballif BA, Smogorzewska A, McDonald ER 3rd, Hurov KE, Luo J, Bakalarski CE, Zhao Z, Solimini N, Lerenthal Y et al (2007) ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Science 316:1160-1166
-
(2007)
Science
, vol.316
, pp. 1160-1166
-
-
Matsuoka, S.1
Ballif, B.A.2
Smogorzewska, A.3
McDonald III, E.R.4
Hurov, K.E.5
Luo, J.6
Bakalarski, C.E.7
Zhao, Z.8
Solimini, N.9
Lerenthal, Y.10
-
16
-
-
33748120191
-
Recruitment of ataxia-telangiectasia mutated to the p21(waf1) promoter by ZBP-89 plays a role in mucosal protection
-
1:CAS:528:DC%2BD28XhtVKrurnI 16952553 10.1053/j.gastro.2006.06.014
-
Bai L, Kao JY, Law DJ, Merchant JL (2006) Recruitment of ataxia-telangiectasia mutated to the p21(waf1) promoter by ZBP-89 plays a role in mucosal protection. Gastroenterology 131:841-852
-
(2006)
Gastroenterology
, vol.131
, pp. 841-852
-
-
Bai, L.1
Kao, J.Y.2
Law, D.J.3
Merchant, J.L.4
-
17
-
-
34250183104
-
ATM phosphorylates ZBP-89 at Ser202 to potentiate p21waf1 induction by butyrate
-
1:CAS:528:DC%2BD2sXmsFyrs7o%3D 1994773 17560543 10.1016/j.bbrc.2007.05. 197
-
Bai L, Merchant JL (2007) ATM phosphorylates ZBP-89 at Ser202 to potentiate p21waf1 induction by butyrate. Biochem Biophys Res Commun 359:817-821
-
(2007)
Biochem Biophys Res Commun
, vol.359
, pp. 817-821
-
-
Bai, L.1
Merchant, J.L.2
-
18
-
-
80054891760
-
Zfp281 functions as a transcriptional repressor for pluripotency of mouse embryonic stem cells
-
1:CAS:528:DC%2BC3MXhs1ejsLfF 3272666 21915945 10.1002/stem.736
-
Fidalgo M, Shekar PC, Ang YS, Fujiwara Y, Orkin SH, Wang J (2011) Zfp281 functions as a transcriptional repressor for pluripotency of mouse embryonic stem cells. Stem Cells 29:1705-1716
-
(2011)
Stem Cells
, vol.29
, pp. 1705-1716
-
-
Fidalgo, M.1
Shekar, P.C.2
Ang, Y.S.3
Fujiwara, Y.4
Orkin, S.H.5
Wang, J.6
-
19
-
-
0037313817
-
Heterozygosity with respect to Zfp148 causes complete loss of fetal germ cells during mouse embryogenesis
-
1:CAS:528:DC%2BD3sXnsFSlug%3D%3D 12524542 10.1038/ng1072
-
Takeuchi A, Mishina Y, Miyaishi O, Kojima E, Hasegawa T, Isobe K (2003) Heterozygosity with respect to Zfp148 causes complete loss of fetal germ cells during mouse embryogenesis. Nat Genet 33:172-176
-
(2003)
Nat Genet
, vol.33
, pp. 172-176
-
-
Takeuchi, A.1
Mishina, Y.2
Miyaishi, O.3
Kojima, E.4
Hasegawa, T.5
Isobe, K.6
-
20
-
-
33644996746
-
An isoform of ZBP-89 predisposes the colon to colitis
-
1:CAS:528:DC%2BD28XjtFSrs7g%3D 1390687 16517939 10.1093/nar/gkl022
-
Law DJ, Labut EM, Adams RD, Merchant JL (2006) An isoform of ZBP-89 predisposes the colon to colitis. Nucleic Acids Res 34:1342-1350
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 1342-1350
-
-
Law, D.J.1
Labut, E.M.2
Adams, R.D.3
Merchant, J.L.4
-
21
-
-
84876708413
-
ZBP-89 regulates expression of tryptophan hydroxylase i and mucosal defense against Salmonella typhimurium in mice
-
1:CAS:528:DC%2BC3sXovVCjtLY%3D 23395646 10.1053/j.gastro.2013.01.057 1477 e1461-1469
-
Essien BE, Grasberger H, Romain RD, Law DJ, Veniaminova NA, Saqui-Salces M, El-Zaatari M, Tessier A, Hayes MM, Yang AC et al (2013) ZBP-89 regulates expression of tryptophan hydroxylase I and mucosal defense against Salmonella typhimurium in mice. Gastroenterology 144:1466-1477, 1477 e1461-1469
-
(2013)
Gastroenterology
, vol.144
, pp. 1466-1477
-
-
Essien, B.E.1
Grasberger, H.2
Romain, R.D.3
Law, D.J.4
Veniaminova, N.A.5
Saqui-Salces, M.6
El-Zaatari, M.7
Tessier, A.8
Hayes, M.M.9
Yang, A.C.10
-
22
-
-
84873529532
-
Zfp148 deficiency causes lung maturation defects and lethality in newborn mice that are rescued by deletion of p53 or antioxidant treatment
-
1:CAS:528:DC%2BC3sXivFGqu7s%3D 3566028 23405202 10.1371/journal.pone. 0055720
-
Sayin VI, Nilton A, Ibrahim MX, Agren P, Larsson E, Petit MM, Hulten LM, Stahlman M, Johansson BR, Bergo MO et al (2013) Zfp148 deficiency causes lung maturation defects and lethality in newborn mice that are rescued by deletion of p53 or antioxidant treatment. PLoS One 8:e55720
-
(2013)
PLoS One
, vol.8
, pp. 55720
-
-
Sayin, V.I.1
Nilton, A.2
Ibrahim, M.X.3
Agren, P.4
Larsson, E.5
Petit, M.M.6
Hulten, L.M.7
Stahlman, M.8
Johansson, B.R.9
Bergo, M.O.10
-
23
-
-
0035167812
-
The mouse snail gene encodes a key regulator of the epithelial- mesenchymal transition
-
1:CAS:528:DC%2BD3MXotl2gtbk%3D 99982 11689706 10.1128/MCB.21.23.8184- 8188.2001
-
Carver EA, Jiang R, Lan Y, Oram KF, Gridley T (2001) The mouse snail gene encodes a key regulator of the epithelial-mesenchymal transition. Mol Cell Biol 21:8184-8188
-
(2001)
Mol Cell Biol
, vol.21
, pp. 8184-8188
-
-
Carver, E.A.1
Jiang, R.2
Lan, Y.3
Oram, K.F.4
Gridley, T.5
-
24
-
-
32344434185
-
Generation of a Snail1 (Snai1) conditional null allele
-
1:CAS:528:DC%2BD28XhvFGmsb8%3D 16397867 10.1002/gene.20178
-
Murray SA, Carver EA, Gridley T (2006) Generation of a Snail1 (Snai1) conditional null allele. Genesis 44:7-11
-
(2006)
Genesis
, vol.44
, pp. 7-11
-
-
Murray, S.A.1
Carver, E.A.2
Gridley, T.3
-
25
-
-
84873050284
-
Regulatory networks defining EMT during cancer initiation and progression
-
23344542 10.1038/nrc3447
-
De Craene B, Berx G (2013) Regulatory networks defining EMT during cancer initiation and progression. Nat Rev Cancer 13:97-110
-
(2013)
Nat Rev Cancer
, vol.13
, pp. 97-110
-
-
De Craene, B.1
Berx, G.2
-
26
-
-
67650999875
-
The basics of epithelial-mesenchymal transition
-
1:CAS:528:DC%2BD1MXntVCjtr0%3D 2689101 19487818 10.1172/JCI39104
-
Kalluri R, Weinberg RA (2009) The basics of epithelial-mesenchymal transition. J Clin Invest 119:1420-1428
-
(2009)
J Clin Invest
, vol.119
, pp. 1420-1428
-
-
Kalluri, R.1
Weinberg, R.A.2
-
27
-
-
44449144396
-
Epithelial-mesenchymal transition: At the crossroads of development and tumor metastasis
-
1:CAS:528:DC%2BD1cXnsVCrs7g%3D 18539112 10.1016/j.devcel.2008.05.009
-
Yang J, Weinberg RA (2008) Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. Dev Cell 14:818-829
-
(2008)
Dev Cell
, vol.14
, pp. 818-829
-
-
Yang, J.1
Weinberg, R.A.2
-
28
-
-
34848826864
-
Epithelial-mesenchymal and mesenchymal-epithelial transitions in carcinoma progression
-
1:CAS:528:DC%2BD2sXhtFKnu7rE 17680632 10.1002/jcp.21223
-
Hugo H, Ackland ML, Blick T, Lawrence MG, Clements JA, Williams ED, Thompson EW (2007) Epithelial-mesenchymal and mesenchymal-epithelial transitions in carcinoma progression. J Cell Physiol 213:374-383
-
(2007)
J Cell Physiol
, vol.213
, pp. 374-383
-
-
Hugo, H.1
Ackland, M.L.2
Blick, T.3
Lawrence, M.G.4
Clements, J.A.5
Williams, E.D.6
Thompson, E.W.7
-
29
-
-
33645302628
-
The epithelial-mesenchymal transition: New insights in signaling, development, and disease
-
1:CAS:528:DC%2BD28XjtF2qsLs%3D 2063755 16567498 10.1083/jcb.200601018
-
Lee JM, Dedhar S, Kalluri R, Thompson EW (2006) The epithelial- mesenchymal transition: new insights in signaling, development, and disease. J Cell Biol 172:973-981
-
(2006)
J Cell Biol
, vol.172
, pp. 973-981
-
-
Lee, J.M.1
Dedhar, S.2
Kalluri, R.3
Thompson, E.W.4
-
30
-
-
63049123066
-
Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
-
1:CAS:528:DC%2BD1MXis1Chtb0%3D 19262571 10.1038/nrc2620
-
Polyak K, Weinberg RA (2009) Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat Rev Cancer 9:265-273
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 265-273
-
-
Polyak, K.1
Weinberg, R.A.2
-
31
-
-
0036595629
-
Epithelial-mesenchymal transitions in tumour progression
-
1:CAS:528:DC%2BD38Xksl2ltr8%3D 12189386 10.1038/nrc822
-
Thiery JP (2002) Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer 2:442-454
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 442-454
-
-
Thiery, J.P.1
-
32
-
-
33244463813
-
Complex networks orchestrate epithelial-mesenchymal transitions
-
1:CAS:528:DC%2BD28XhtlWltLg%3D 16493418 10.1038/nrm1835
-
Thiery JP, Sleeman JP (2006) Complex networks orchestrate epithelial-mesenchymal transitions. Nat Rev Mol Cell Biol 7:131-142
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 131-142
-
-
Thiery, J.P.1
Sleeman, J.P.2
-
33
-
-
0027296534
-
Epithelium-mesenchyme interconversion as example of epithelial plasticity
-
1:STN:280:DyaK3szht1Gntg%3D%3D 8323734 10.1111/j.1699-0463.1993.tb00109.x
-
Boyer B, Thiery JP (1993) Epithelium-mesenchyme interconversion as example of epithelial plasticity. APMIS 101:257-268
-
(1993)
APMIS
, vol.101
, pp. 257-268
-
-
Boyer, B.1
Thiery, J.P.2
-
34
-
-
34249289041
-
Snail, Zeb and bHLH factors in tumour progression: An alliance against the epithelial phenotype?
-
1:CAS:528:DC%2BD2sXls1Kjs70%3D 17508028 10.1038/nrc2131
-
Peinado H, Olmeda D, Cano A (2007) Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat Rev Cancer 7:415-428
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 415-428
-
-
Peinado, H.1
Olmeda, D.2
Cano, A.3
-
35
-
-
77957262381
-
Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes
-
1:CAS:528:DC%2BC3cXhtFaqurfK 2932589 20713713 10.1073/pnas.1004900107
-
Taube JH, Herschkowitz JI, Komurov K, Zhou AY, Gupta S, Yang J, Hartwell K, Onder TT, Gupta PB, Evans KW et al (2010) Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes. Proc Natl Acad Sci U S A 107:15449-15454
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 15449-15454
-
-
Taube, J.H.1
Herschkowitz, J.I.2
Komurov, K.3
Zhou, A.Y.4
Gupta, S.5
Yang, J.6
Hartwell, K.7
Onder, T.T.8
Gupta, P.B.9
Evans, K.W.10
-
36
-
-
84867578091
-
EMT-activating transcription factors in cancer: Beyond EMT and tumor invasiveness
-
1:CAS:528:DC%2BC38XhtlKltb7M 22945800 10.1007/s00018-012-1122-2
-
Sanchez-Tillo E, Liu Y, de Barrios O, Siles L, Fanlo L, Cuatrecasas M, Darling DS, Dean DC, Castells A, Postigo A (2012) EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness. Cell Mol Life Sci 69:3429-3456
-
(2012)
Cell Mol Life Sci
, vol.69
, pp. 3429-3456
-
-
Sanchez-Tillo, E.1
Liu, Y.2
De Barrios, O.3
Siles, L.4
Fanlo, L.5
Cuatrecasas, M.6
Darling, D.S.7
Dean, D.C.8
Castells, A.9
Postigo, A.10
-
37
-
-
67650996754
-
Biomarkers for epithelial-mesenchymal transitions
-
1:CAS:528:DC%2BD1MXntVCjtro%3D 2689132 19487819 10.1172/JCI36183
-
Zeisberg M, Neilson EG (2009) Biomarkers for epithelial-mesenchymal transitions. J Clin Invest 119:1429-1437
-
(2009)
J Clin Invest
, vol.119
, pp. 1429-1437
-
-
Zeisberg, M.1
Neilson, E.G.2
-
38
-
-
63049090100
-
Metastasis: From dissemination to organ-specific colonization
-
1:CAS:528:DC%2BD1MXjsFSrsr4%3D 19308067 10.1038/nrc2622
-
Nguyen DX, Bos PD, Massague J (2009) Metastasis: from dissemination to organ-specific colonization. Nat Rev Cancer 9:274-284
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 274-284
-
-
Nguyen, D.X.1
Bos, P.D.2
Massague, J.3
-
39
-
-
80054686286
-
Tumor metastasis: Molecular insights and evolving paradigms
-
1:CAS:528:DC%2BC3MXhtlaksb3N 3261217 22000009 10.1016/j.cell.2011.09.024
-
Valastyan S, Weinberg RA (2011) Tumor metastasis: molecular insights and evolving paradigms. Cell 147:275-292
-
(2011)
Cell
, vol.147
, pp. 275-292
-
-
Valastyan, S.1
Weinberg, R.A.2
-
40
-
-
84856102456
-
MiR-34 and SNAIL: Another double-negative feedback loop controlling cellular plasticity/EMT governed by p53
-
1:CAS:528:DC%2BC38XjtVSru7k%3D 22214667 10.4161/cc.11.2.18900
-
Brabletz T (2012) MiR-34 and SNAIL: another double-negative feedback loop controlling cellular plasticity/EMT governed by p53. Cell Cycle 11:215-216
-
(2012)
Cell Cycle
, vol.11
, pp. 215-216
-
-
Brabletz, T.1
-
41
-
-
33645294070
-
Oncomirs - MicroRNAs with a role in cancer
-
1:CAS:528:DC%2BD28XivVyqtrs%3D 16557279 10.1038/nrc1840
-
Esquela-Kerscher A, Slack FJ (2006) Oncomirs - microRNAs with a role in cancer. Nat Rev Cancer 6:259-269
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 259-269
-
-
Esquela-Kerscher, A.1
Slack, F.J.2
-
42
-
-
84866423871
-
MicroRNAs in the p53 network: Micromanagement of tumour suppression
-
1:CAS:528:DC%2BC38Xht1WktrvJ 22898542 10.1038/nrc3318
-
Hermeking H (2012) MicroRNAs in the p53 network: micromanagement of tumour suppression. Nat Rev Cancer 12:613-626
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 613-626
-
-
Hermeking, H.1
-
43
-
-
58249088751
-
MicroRNAs: Target recognition and regulatory functions
-
1:CAS:528:DC%2BD1MXhs1Kiuro%3D 3794896 19167326 10.1016/j.cell.2009.01. 002
-
Bartel DP (2009) MicroRNAs: target recognition and regulatory functions. Cell 136:215-233
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
44
-
-
60149095444
-
Most mammalian mRNAs are conserved targets of microRNAs
-
1:CAS:528:DC%2BD1MXptFWjuw%3D%3D 2612969 18955434 10.1101/gr.082701.108
-
Friedman RC, Farh KK, Burge CB, Bartel DP (2009) Most mammalian mRNAs are conserved targets of microRNAs. Genome Res 19:92-105
-
(2009)
Genome Res
, vol.19
, pp. 92-105
-
-
Friedman, R.C.1
Farh, K.K.2
Burge, C.B.3
Bartel, D.P.4
-
45
-
-
78751477191
-
Gene silencing by microRNAs: Contributions of translational repression and mRNA decay
-
1:CAS:528:DC%2BC3MXmsVelsw%3D%3D 21245828 10.1038/nrg2936
-
Huntzinger E, Izaurralde E (2011) Gene silencing by microRNAs: contributions of translational repression and mRNA decay. Nat Rev Genet 12:99-110
-
(2011)
Nat Rev Genet
, vol.12
, pp. 99-110
-
-
Huntzinger, E.1
Izaurralde, E.2
-
46
-
-
84888875112
-
SNAIL and miR-34a feed-forward regulation of ZNF281/ZBP99 promotes epithelial-mesenchymal transition
-
1:CAS:528:DC%2BC3sXhslWjtLrP 24185900 10.1038/emboj.2013.236
-
Hahn S, Jackstadt R, Siemens H, Hunten S, Hermeking H (2013) SNAIL and miR-34a feed-forward regulation of ZNF281/ZBP99 promotes epithelial-mesenchymal transition. EMBO J 32:3079-3095
-
(2013)
EMBO J
, vol.32
, pp. 3079-3095
-
-
Hahn, S.1
Jackstadt, R.2
Siemens, H.3
Hunten, S.4
Hermeking, H.5
-
47
-
-
84897561550
-
IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis
-
1:CAS:528:DC%2BC2cXmtVGgur4%3D 3973098 24642471 10.1172/JCI73531
-
Rokavec M, Oner MG, Li H, Jackstadt R, Jiang L, Lodygin D, Kaller M, Horst D, Ziegler PK, Schwitalla S et al (2014) IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis. J Clin Invest 124:1853-1867
-
(2014)
J Clin Invest
, vol.124
, pp. 1853-1867
-
-
Rokavec, M.1
Oner, M.G.2
Li, H.3
Jackstadt, R.4
Jiang, L.5
Lodygin, D.6
Kaller, M.7
Horst, D.8
Ziegler, P.K.9
Schwitalla, S.10
-
48
-
-
84897105479
-
MiR-34 cooperates with p53 in suppression of prostate cancer by joint regulation of stem cell compartment
-
1:CAS:528:DC%2BC2cXktlWgtrk%3D 3988786 24630988 10.1016/j.celrep.2014.02. 023
-
Cheng CY, Hwang CI, Corney DC, Flesken-Nikitin A, Jiang L, Oner GM, Munroe RJ, Schimenti JC, Hermeking H, Nikitin AY (2014) miR-34 cooperates with p53 in suppression of prostate cancer by joint regulation of stem cell compartment. Cell Rep 6:1000-1007
-
(2014)
Cell Rep
, vol.6
, pp. 1000-1007
-
-
Cheng, C.Y.1
Hwang, C.I.2
Corney, D.C.3
Flesken-Nikitin, A.4
Jiang, L.5
Oner, G.M.6
Munroe, R.J.7
Schimenti, J.C.8
Hermeking, H.9
Nikitin, A.Y.10
-
49
-
-
84896897599
-
A positive feedback between p53 and miR-34 miRNAs mediates tumor suppression
-
1:CAS:528:DC%2BC2cXlt1elsbo%3D 24532687 10.1101/gad.233585.113
-
Okada N, Lin CP, Ribeiro MC, Biton A, Lai G, He X, Bu P, Vogel H, Jablons DM, Keller AC et al (2014) A positive feedback between p53 and miR-34 miRNAs mediates tumor suppression. Genes Dev 28:438-450
-
(2014)
Genes Dev
, vol.28
, pp. 438-450
-
-
Okada, N.1
Lin, C.P.2
Ribeiro, M.C.3
Biton, A.4
Lai, G.5
He, X.6
Bu, P.7
Vogel, H.8
Jablons, D.M.9
Keller, A.C.10
-
50
-
-
84055184850
-
MiR-34 and SNAIL form a double-negative feedback loop to regulate epithelial-mesenchymal transitions
-
1:CAS:528:DC%2BC38XhvVKlurg%3D 22134354 10.4161/cc.10.24.18552
-
Siemens H, Jackstadt R, Hunten S, Kaller M, Menssen A, Gotz U, Hermeking H (2011) miR-34 and SNAIL form a double-negative feedback loop to regulate epithelial-mesenchymal transitions. Cell Cycle 10:4256-4271
-
(2011)
Cell Cycle
, vol.10
, pp. 4256-4271
-
-
Siemens, H.1
Jackstadt, R.2
Hunten, S.3
Kaller, M.4
Menssen, A.5
Gotz, U.6
Hermeking, H.7
-
51
-
-
33846929680
-
Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach
-
1:CAS:528:DC%2BD2sXnvFClsbw%3D 17314511 10.4161/cc.6.2.3742
-
Koch HB, Zhang R, Verdoodt B, Bailey A, Zhang CD, Yates JR 3rd, Menssen A, Hermeking H (2007) Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach. Cell Cycle 6:205-217
-
(2007)
Cell Cycle
, vol.6
, pp. 205-217
-
-
Koch, H.B.1
Zhang, R.2
Verdoodt, B.3
Bailey, A.4
Zhang, C.D.5
Yates III, J.R.6
Menssen, A.7
Hermeking, H.8
-
52
-
-
84873031758
-
ZNF281 knockdown induced osteogenic differentiation of human multipotent stem cells in vivo and in vitro
-
Seo KW, Roh KH, Bhandari DR, Park SB, Lee SK, Kang KS (2013) ZNF281 knockdown induced osteogenic differentiation of human multipotent stem cells in vivo and in vitro. Cell Transplant 22:29-40
-
(2013)
Cell Transplant
, vol.22
, pp. 29-40
-
-
Seo, K.W.1
Roh, K.H.2
Bhandari, D.R.3
Park, S.B.4
Lee, S.K.5
Kang, K.S.6
-
53
-
-
0346363757
-
Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex
-
Peinado H, Ballestar E, Esteller M, Cano A (2004) Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex. Mol Cell Biol 24:306-319
-
(2004)
Mol Cell Biol
, vol.24
, pp. 306-319
-
-
Peinado, H.1
Ballestar, E.2
Esteller, M.3
Cano, A.4
-
54
-
-
84892923276
-
P53-induced miR-15a/16-1 and AP4 form a double-negative feedback loop to regulate epithelial-mesenchymal transition and metastasis in colorectal cancer
-
1:CAS:528:DC%2BC2cXptVagtQ%3D%3D 24285725 10.1158/0008-5472.CAN-13-2203
-
Shi L, Jackstadt R, Siemens H, Li H, Kirchner T, Hermeking H (2014) p53-induced miR-15a/16-1 and AP4 form a double-negative feedback loop to regulate epithelial-mesenchymal transition and metastasis in colorectal cancer. Cancer Res 74:532-542
-
(2014)
Cancer Res
, vol.74
, pp. 532-542
-
-
Shi, L.1
Jackstadt, R.2
Siemens, H.3
Li, H.4
Kirchner, T.5
Hermeking, H.6
-
55
-
-
33751092246
-
A protein interaction network for pluripotency of embryonic stem cells
-
1:CAS:528:DC%2BD28Xht1SgtbzM 17093407 10.1038/nature05284
-
Wang J, Rao S, Chu J, Shen X, Levasseur DN, Theunissen TW, Orkin SH (2006) A protein interaction network for pluripotency of embryonic stem cells. Nature 444:364-368
-
(2006)
Nature
, vol.444
, pp. 364-368
-
-
Wang, J.1
Rao, S.2
Chu, J.3
Shen, X.4
Levasseur, D.N.5
Theunissen, T.W.6
Orkin, S.H.7
-
56
-
-
84867054759
-
Zfp281 mediates NANOG autorepression through recruitment of the NuRD complex and inhibits somatic cell reprogramming
-
Fidalgo M, Faiola F, Pereira CF, Ding J, Saunders A, Gingold J, Schaniel C, Lemischka IR, Silva JC, Wang J (2012) Zfp281 mediates NANOG autorepression through recruitment of the NuRD complex and inhibits somatic cell reprogramming. Proc Natl Acad Sci U S A, pp. 16202-16207
-
(2012)
Proc Natl Acad Sci U S A
, pp. 16202-16207
-
-
Fidalgo, M.1
Faiola, F.2
Pereira, C.F.3
Ding, J.4
Saunders, A.5
Gingold, J.6
Schaniel, C.7
Lemischka, I.R.8
Silva, J.C.9
Wang, J.10
-
57
-
-
79955781510
-
Identification of pluripotency genes in the fish medaka
-
1:CAS:528:DC%2BC3MXlsl2gsrs%3D 3088286 21547061 10.7150/ijbs.7.440
-
Wang D, Manali D, Wang T, Bhat N, Hong N, Li Z, Wang L, Yan Y, Liu R, Hong Y (2011) Identification of pluripotency genes in the fish medaka. Int J Biol Sci 7:440-451
-
(2011)
Int J Biol Sci
, vol.7
, pp. 440-451
-
-
Wang, D.1
Manali, D.2
Wang, T.3
Bhat, N.4
Hong, N.5
Li, Z.6
Wang, L.7
Yan, Y.8
Liu, R.9
Hong, Y.10
-
58
-
-
84877263242
-
A microRNA miR-34a-regulated bimodal switch targets notch in colon cancer stem cells
-
1:CAS:528:DC%2BC3sXmvF2ltbg%3D 3646336 23642368 10.1016/j.stem.2013.03. 002
-
Bu P, Chen KY, Chen JH, Wang L, Walters J, Shin YJ, Goerger JP, Sun J, Witherspoon M, Rakhilin N et al (2013) A microRNA miR-34a-regulated bimodal switch targets notch in colon cancer stem cells. Cell Stem Cell 12:602-615
-
(2013)
Cell Stem Cell
, vol.12
, pp. 602-615
-
-
Bu, P.1
Chen, K.Y.2
Chen, J.H.3
Wang, L.4
Walters, J.5
Shin, Y.J.6
Goerger, J.P.7
Sun, J.8
Witherspoon, M.9
Rakhilin, N.10
-
59
-
-
40749111551
-
A skin microRNA promotes differentiation by repressing 'stemness'
-
1:CAS:528:DC%2BD1cXjt1Gnu7Y%3D 18311128 10.1038/nature06642
-
Yi R, Poy MN, Stoffel M, Fuchs E (2008) A skin microRNA promotes differentiation by repressing 'stemness'. Nature 452:225-229
-
(2008)
Nature
, vol.452
, pp. 225-229
-
-
Yi, R.1
Poy, M.N.2
Stoffel, M.3
Fuchs, E.4
-
60
-
-
73049110243
-
The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
-
1:CAS:528:DC%2BD1MXhsV2gsLnM 19935649 10.1038/ncb1998
-
Wellner U, Schubert J, Burk UC, Schmalhofer O, Zhu F, Sonntag A, Waldvogel B, Vannier C, Darling D, zur Hausen A et al (2009) The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs. Nat Cell Biol 11:1487-1495
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1487-1495
-
-
Wellner, U.1
Schubert, J.2
Burk, U.C.3
Schmalhofer, O.4
Zhu, F.5
Sonntag, A.6
Waldvogel, B.7
Vannier, C.8
Darling, D.9
Zur Hausen, A.10
-
61
-
-
84901471917
-
Epigenetic silencing of microRNA-203 is required for EMT and cancer stem cell properties
-
3776231 24045437 10.1038/srep02687
-
Taube JH, Malouf GG, Lu E, Sphyris N, Vijay V, Ramachandran PP, Ueno KR, Gaur S, Nicoloso MS, Rossi S et al (2013) Epigenetic silencing of microRNA-203 is required for EMT and cancer stem cell properties. Sci Rep 3:2687
-
(2013)
Sci Rep
, vol.3
, pp. 2687
-
-
Taube, J.H.1
Malouf, G.G.2
Lu, E.3
Sphyris, N.4
Vijay, V.5
Ramachandran, P.P.6
Ueno, K.R.7
Gaur, S.8
Nicoloso, M.S.9
Rossi, S.10
-
62
-
-
84859720222
-
A novel network integrating a miRNA-203/SNAI1 feedback loop which regulates epithelial to mesenchymal transition
-
1:CAS:528:DC%2BC38Xmt1ehs70%3D 3325969 22514743 10.1371/journal.pone. 0035440
-
Moes M, Le Bechec A, Crespo I, Laurini C, Halavatyi A, Vetter G, Del Sol A, Friederich E (2012) A novel network integrating a miRNA-203/SNAI1 feedback loop which regulates epithelial to mesenchymal transition. PLoS One 7:e35440
-
(2012)
PLoS One
, vol.7
, pp. 35440
-
-
Moes, M.1
Le Bechec, A.2
Crespo, I.3
Laurini, C.4
Halavatyi, A.5
Vetter, G.6
Del Sol, A.7
Friederich, E.8
-
63
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
1:CAS:528:DC%2BD1cXmsVOru7w%3D 2728032 18485877 10.1016/j.cell.2008.03. 027
-
Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY, Brooks M, Reinhard F, Zhang CC, Shipitsin M et al (2008) The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133:704-715
-
(2008)
Cell
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
Eaton, E.N.4
Ayyanan, A.5
Zhou, A.Y.6
Brooks, M.7
Reinhard, F.8
Zhang, C.C.9
Shipitsin, M.10
-
64
-
-
14944357138
-
Wnt, stem cells and cancer in the intestine
-
1:CAS:528:DC%2BD2MXhtl2rs7s%3D 15715524 10.1042/BC20040094
-
Pinto D, Clevers H (2005) Wnt, stem cells and cancer in the intestine. Biol Cell 97:185-196
-
(2005)
Biol Cell
, vol.97
, pp. 185-196
-
-
Pinto, D.1
Clevers, H.2
-
65
-
-
39749092525
-
Current view: Intestinal stem cells and signaling
-
1:CAS:528:DC%2BD1cXktlehtb0%3D 18325394 10.1053/j.gastro.2008.01.079
-
Scoville DH, Sato T, He XC, Li L (2008) Current view: intestinal stem cells and signaling. Gastroenterology 134:849-864
-
(2008)
Gastroenterology
, vol.134
, pp. 849-864
-
-
Scoville, D.H.1
Sato, T.2
He, X.C.3
Li, L.4
-
66
-
-
25444495269
-
Opinion: Migrating cancer stem cells - An integrated concept of malignant tumour progression
-
1:CAS:528:DC%2BD2MXpsleksLw%3D 16148886 10.1038/nrc1694
-
Brabletz T, Jung A, Spaderna S, Hlubek F, Kirchner T (2005) Opinion: migrating cancer stem cells - an integrated concept of malignant tumour progression. Nat Rev Cancer 5:744-749
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 744-749
-
-
Brabletz, T.1
Jung, A.2
Spaderna, S.3
Hlubek, F.4
Kirchner, T.5
-
67
-
-
74249123570
-
The miR-34 family in cancer and apoptosis
-
1:CAS:528:DC%2BC3cXjt12jtQ%3D%3D 19461653 10.1038/cdd.2009.56
-
Hermeking H (2010) The miR-34 family in cancer and apoptosis. Cell Death Differ 17:193-199
-
(2010)
Cell Death Differ
, vol.17
, pp. 193-199
-
-
Hermeking, H.1
-
68
-
-
84873373140
-
Detection of miR-34a promoter methylation in combination with elevated expression of c-Met and beta-catenin predicts distant metastasis of colon cancer
-
1:CAS:528:DC%2BC3sXitVOhtLY%3D 23243217 10.1158/1078-0432.CCR-12-1703
-
Siemens H, Neumann J, Jackstadt R, Mansmann U, Horst D, Kirchner T, Hermeking H (2013) Detection of miR-34a promoter methylation in combination with elevated expression of c-Met and beta-catenin predicts distant metastasis of colon cancer. Clin Cancer Res 19:710-720
-
(2013)
Clin Cancer Res
, vol.19
, pp. 710-720
-
-
Siemens, H.1
Neumann, J.2
Jackstadt, R.3
Mansmann, U.4
Horst, D.5
Kirchner, T.6
Hermeking, H.7
-
69
-
-
0035964349
-
Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment
-
1:CAS:528:DC%2BD3MXmvFWiu7o%3D 56965 11526241 10.1073/pnas.171610498
-
Brabletz T, Jung A, Reu S, Porzner M, Hlubek F, Kunz-Schughart LA, Knuechel R, Kirchner T (2001) Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment. Proc Natl Acad Sci U S A 98:10356-10361
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 10356-10361
-
-
Brabletz, T.1
Jung, A.2
Reu, S.3
Porzner, M.4
Hlubek, F.5
Kunz-Schughart, L.A.6
Knuechel, R.7
Kirchner, T.8
-
70
-
-
84887101163
-
MicroRNAs and other non-coding RNAs as targets for anticancer drug development
-
1:CAS:528:DC%2BC3sXhs12ks73I 24172333 10.1038/nrd4140
-
Ling H, Fabbri M, Calin GA (2013) MicroRNAs and other non-coding RNAs as targets for anticancer drug development. Nat Rev Drug Discov 12:847-865
-
(2013)
Nat Rev Drug Discov
, vol.12
, pp. 847-865
-
-
Ling, H.1
Fabbri, M.2
Calin, G.A.3
-
71
-
-
84869219338
-
MiR-34 - A microRNA replacement therapy is headed to the clinic
-
1:CAS:528:DC%2BC3sXhtFSltL3I 3387671 22783274 10.3389/fgene.2012.00120
-
Bader AG (2012) miR-34 - a microRNA replacement therapy is headed to the clinic. Front Genet 3:120
-
(2012)
Front Genet
, vol.3
, pp. 120
-
-
Bader, A.G.1
-
72
-
-
84876301908
-
Differential localization of LGR5 and NANOG in clusters of colon cancer stem cells
-
1:CAS:528:DC%2BC38XhsFKgu7nP 23098761 10.1016/j.acthis.2012.09.003
-
Amsterdam A, Raanan C, Schreiber L, Freyhan O, Fabrikant Y, Melzer E, Givol D (2013) Differential localization of LGR5 and NANOG in clusters of colon cancer stem cells. Acta Histochem 115:320-329
-
(2013)
Acta Histochem
, vol.115
, pp. 320-329
-
-
Amsterdam, A.1
Raanan, C.2
Schreiber, L.3
Freyhan, O.4
Fabrikant, Y.5
Melzer, E.6
Givol, D.7
-
73
-
-
84882880865
-
Dysregulation of CDX1, CDX2 and SOX2 in patients with gastric cancer also affects the non-malignant mucosa
-
23613102 10.1136/jclinpath-2013-201448
-
Bornschein J, Toth K, Selgrad M, Kuester D, Wex T, Molnar B, Tulassay Z, Malfertheiner P (2013) Dysregulation of CDX1, CDX2 and SOX2 in patients with gastric cancer also affects the non-malignant mucosa. J Clin Pathol 66:819-822
-
(2013)
J Clin Pathol
, vol.66
, pp. 819-822
-
-
Bornschein, J.1
Toth, K.2
Selgrad, M.3
Kuester, D.4
Wex, T.5
Molnar, B.6
Tulassay, Z.7
Malfertheiner, P.8
-
74
-
-
84866161727
-
SOX2 gene regulates the transcriptional network of oncogenes and affects tumorigenesis of human lung cancer cells
-
1:CAS:528:DC%2BC38Xnslygs7k%3D 3352903 22615765 10.1371/journal.pone. 0036326
-
Chen S, Xu Y, Chen Y, Li X, Mou W, Wang L, Liu Y, Reisfeld RA, Xiang R, Lv D et al (2012) SOX2 gene regulates the transcriptional network of oncogenes and affects tumorigenesis of human lung cancer cells. PLoS One 7:e36326
-
(2012)
PLoS One
, vol.7
, pp. 36326
-
-
Chen, S.1
Xu, Y.2
Chen, Y.3
Li, X.4
Mou, W.5
Wang, L.6
Liu, Y.7
Reisfeld, R.A.8
Xiang, R.9
Lv, D.10
-
75
-
-
84866702740
-
Embryonic NANOG activity defines colorectal cancer stem cells and modulates through AP1- and TCF-dependent mechanisms
-
1:CAS:528:DC%2BC38XhsF2ntrfI 22851508 10.1002/stem.1182
-
Ibrahim EE, Babaei-Jadidi R, Saadeddin A, Spencer-Dene B, Hossaini S, Abuzinadah M, Li N, Fadhil W, Ilyas M, Bonnet D et al (2012) Embryonic NANOG activity defines colorectal cancer stem cells and modulates through AP1- and TCF-dependent mechanisms. Stem Cells 30:2076-2087
-
(2012)
Stem Cells
, vol.30
, pp. 2076-2087
-
-
Ibrahim, E.E.1
Babaei-Jadidi, R.2
Saadeddin, A.3
Spencer-Dene, B.4
Hossaini, S.5
Abuzinadah, M.6
Li, N.7
Fadhil, W.8
Ilyas, M.9
Bonnet, D.10
-
76
-
-
79251564420
-
Expression of the embryonic stem cell marker SOX2 in early-stage breast carcinoma
-
3038979 21276239 10.1186/1471-2407-11-42
-
Lengerke C, Fehm T, Kurth R, Neubauer H, Scheble V, Muller F, Schneider F, Petersen K, Wallwiener D, Kanz L et al (2011) Expression of the embryonic stem cell marker SOX2 in early-stage breast carcinoma. BMC Cancer 11:42
-
(2011)
BMC Cancer
, vol.11
, pp. 42
-
-
Lengerke, C.1
Fehm, T.2
Kurth, R.3
Neubauer, H.4
Scheble, V.5
Muller, F.6
Schneider, F.7
Petersen, K.8
Wallwiener, D.9
Kanz, L.10
-
77
-
-
84901190709
-
The pluripotency factor nanog promotes breast cancer tumorigenesis and metastasis
-
doi: 10.1038/onc.2013.209
-
Lu X, Mazur SJ, Lin T, Appella E, Xu Y (2013) The pluripotency factor nanog promotes breast cancer tumorigenesis and metastasis. Oncogene. doi: 10.1038/onc.2013.209
-
(2013)
Oncogene
-
-
Lu, X.1
Mazur, S.J.2
Lin, T.3
Appella, E.4
Xu, Y.5
-
78
-
-
77956224492
-
Evidence that SOX2 overexpression is oncogenic in the lung
-
2883553 20548776 10.1371/journal.pone.0011022
-
Lu Y, Futtner C, Rock JR, Xu X, Whitworth W, Hogan BL, Onaitis MW (2010) Evidence that SOX2 overexpression is oncogenic in the lung. PLoS One 5:e11022
-
(2010)
PLoS One
, vol.5
, pp. 11022
-
-
Lu, Y.1
Futtner, C.2
Rock, J.R.3
Xu, X.4
Whitworth, W.5
Hogan, B.L.6
Onaitis, M.W.7
-
79
-
-
84871778678
-
SOX2 redirects the developmental fate of the intestinal epithelium toward a premature gastric phenotype
-
1:CAS:528:DC%2BC38XhvFSitbbL 3523556 22679103 10.1093/jmcb/mjs030
-
Raghoebir L, Bakker ER, Mills JC, Swagemakers S, Kempen MB, Munck AB, Driegen S, Meijer D, Grosveld F, Tibboel D et al (2012) SOX2 redirects the developmental fate of the intestinal epithelium toward a premature gastric phenotype. J Mol Cell Biol 4:377-385
-
(2012)
J Mol Cell Biol
, vol.4
, pp. 377-385
-
-
Raghoebir, L.1
Bakker, E.R.2
Mills, J.C.3
Swagemakers, S.4
Kempen, M.B.5
Munck, A.B.6
Driegen, S.7
Meijer, D.8
Grosveld, F.9
Tibboel, D.10
-
80
-
-
20644444118
-
Sox2 expression in human stomach adenocarcinomas with gastric and gastric-and-intestinal-mixed phenotypes
-
1:STN:280:DC%2BD2M3mvV2itA%3D%3D 15910596 10.1111/j.1365-2559.2005.02170. x
-
Tsukamoto T, Mizoshita T, Mihara M, Tanaka H, Takenaka Y, Yamamura Y, Nakamura S, Ushijima T, Tatematsu M (2005) Sox2 expression in human stomach adenocarcinomas with gastric and gastric-and-intestinal-mixed phenotypes. Histopathology 46:649-658
-
(2005)
Histopathology
, vol.46
, pp. 649-658
-
-
Tsukamoto, T.1
Mizoshita, T.2
Mihara, M.3
Tanaka, H.4
Takenaka, Y.5
Yamamura, Y.6
Nakamura, S.7
Ushijima, T.8
Tatematsu, M.9
-
81
-
-
80052771936
-
CD133, OCT4, and NANOG in ulcerative colitis-associated colorectal cancer
-
1:CAS:528:DC%2BC3MXhtlGrtr3K 3406567 22848268
-
Yasuda H, Tanaka K, Okita Y, Araki T, Saigusa S, Toiyama Y, Yokoe T, Yoshiyama S, Kawamoto A, Inoue Y et al (2011) CD133, OCT4, and NANOG in ulcerative colitis-associated colorectal cancer. Oncol Lett 2:1065-1071
-
(2011)
Oncol Lett
, vol.2
, pp. 1065-1071
-
-
Yasuda, H.1
Tanaka, K.2
Okita, Y.3
Araki, T.4
Saigusa, S.5
Toiyama, Y.6
Yokoe, T.7
Yoshiyama, S.8
Kawamoto, A.9
Inoue, Y.10
-
82
-
-
84884204158
-
NANOG modulates stemness in human colorectal cancer
-
1:CAS:528:DC%2BC38XhsFeqs7rF 3556342 23085761 10.1038/onc.2012.461
-
Zhang J, Espinoza LA, Kinders RJ, Lawrence SM, Pfister TD, Zhou M, Veenstra TD, Thorgeirsson SS, Jessup JM (2013) NANOG modulates stemness in human colorectal cancer. Oncogene 32:4397-4405
-
(2013)
Oncogene
, vol.32
, pp. 4397-4405
-
-
Zhang, J.1
Espinoza, L.A.2
Kinders, R.J.3
Lawrence, S.M.4
Pfister, T.D.5
Zhou, M.6
Veenstra, T.D.7
Thorgeirsson, S.S.8
Jessup, J.M.9
-
83
-
-
77955722638
-
The human pluripotency gene NANOG/NANOGP8 is expressed in gastric cancer and associated with tumor development
-
1:CAS:528:DC%2BC3cXmsVKiu70%3D 3436456 22966326
-
Zhang J, Wang X, Chen B, Xiao Z, Li W, Lu Y, Dai J (2010) The human pluripotency gene NANOG/NANOGP8 is expressed in gastric cancer and associated with tumor development. Oncol Lett 1:457-463
-
(2010)
Oncol Lett
, vol.1
, pp. 457-463
-
-
Zhang, J.1
Wang, X.2
Chen, B.3
Xiao, Z.4
Li, W.5
Lu, Y.6
Dai, J.7
-
84
-
-
66349097526
-
Oct4, a novel marker for human gastric cancer
-
1:CAS:528:DC%2BD1MXpt1ehsrk%3D 19347886 10.1002/jso.21270
-
Chen Z, Xu WR, Qian H, Zhu W, Bu XF, Wang S, Yan YM, Mao F, Gu HB, Cao HL et al (2009) Oct4, a novel marker for human gastric cancer. J Surg Oncol 99:414-419
-
(2009)
J Surg Oncol
, vol.99
, pp. 414-419
-
-
Chen, Z.1
Xu, W.R.2
Qian, H.3
Zhu, W.4
Bu, X.F.5
Wang, S.6
Yan, Y.M.7
Mao, F.8
Gu, H.B.9
Cao, H.L.10
-
85
-
-
79955473848
-
Downregulation of transcription factor SOX2 in cancer stem cells suppresses growth and metastasis of lung cancer
-
1:CAS:528:DC%2BC3MXlt1Gkt7s%3D 3101944 21468047 10.1038/bjc.2011.94
-
Xiang R, Liao D, Cheng T, Zhou H, Shi Q, Chuang TS, Markowitz D, Reisfeld RA, Luo Y (2011) Downregulation of transcription factor SOX2 in cancer stem cells suppresses growth and metastasis of lung cancer. Br J Cancer 104:1410-1417
-
(2011)
Br J Cancer
, vol.104
, pp. 1410-1417
-
-
Xiang, R.1
Liao, D.2
Cheng, T.3
Zhou, H.4
Shi, Q.5
Chuang, T.S.6
Markowitz, D.7
Reisfeld, R.A.8
Luo, Y.9
-
86
-
-
84865106429
-
Silencing SOX2 induced mesenchymal-epithelial transition and its expression predicts liver and lymph node metastasis of CRC patients
-
1:CAS:528:DC%2BC38Xht1CnsL7P 3422347 22912670 10.1371/journal.pone. 0041335
-
Han X, Fang X, Lou X, Hua D, Ding W, Foltz G, Hood L, Yuan Y, Lin B (2012) Silencing SOX2 induced mesenchymal-epithelial transition and its expression predicts liver and lymph node metastasis of CRC patients. PLoS One 7:e41335
-
(2012)
PLoS One
, vol.7
, pp. 41335
-
-
Han, X.1
Fang, X.2
Lou, X.3
Hua, D.4
Ding, W.5
Foltz, G.6
Hood, L.7
Yuan, Y.8
Lin, B.9
-
87
-
-
84880637113
-
A signature for induced pluripotent stem cell-associated genes in colorectal cancer
-
23307247 10.1007/s12032-012-0426-2
-
Liu YH, Li Y, Liu XH, Sui HM, Liu YX, Xiao ZQ, Zheng P, Chen L, Yao S, Xing C et al (2013) A signature for induced pluripotent stem cell-associated genes in colorectal cancer. Med Oncol 30:426
-
(2013)
Med Oncol
, vol.30
, pp. 426
-
-
Liu, Y.H.1
Li, Y.2
Liu, X.H.3
Sui, H.M.4
Liu, Y.X.5
Xiao, Z.Q.6
Zheng, P.7
Chen, L.8
Yao, S.9
Xing, C.10
-
88
-
-
77953553879
-
Overexpression of NANOG predicts tumor progression and poor prognosis in colorectal cancer
-
1:CAS:528:DC%2BC3cXpt1Oms7s%3D 20026903 10.4161/cbt.9.4.10666
-
Meng HM, Zheng P, Wang XY, Liu C, Sui HM, Wu SJ, Zhou J, Ding YQ, Li JM (2010) Overexpression of NANOG predicts tumor progression and poor prognosis in colorectal cancer. Cancer Biol Ther 9:295-302
-
(2010)
Cancer Biol Ther
, vol.9
, pp. 295-302
-
-
Meng, H.M.1
Zheng, P.2
Wang, X.Y.3
Liu, C.4
Sui, H.M.5
Wu, S.J.6
Zhou, J.7
Ding, Y.Q.8
Li, J.M.9
-
89
-
-
84868618042
-
Nanog signaling in cancer promotes stem-like phenotype and immune evasion
-
1:CAS:528:DC%2BC38Xhs1CisL%2FO 3484451 23093782 10.1172/JCI64057
-
Noh KH, Kim BW, Song KH, Cho H, Lee YH, Kim JH, Chung JY, Hewitt SM, Seong SY, Mao CP et al (2012) Nanog signaling in cancer promotes stem-like phenotype and immune evasion. J Clin Invest 122:4077-4093
-
(2012)
J Clin Invest
, vol.122
, pp. 4077-4093
-
-
Noh, K.H.1
Kim, B.W.2
Song, K.H.3
Cho, H.4
Lee, Y.H.5
Kim, J.H.6
Chung, J.Y.7
Hewitt, S.M.8
Seong, S.Y.9
Mao, C.P.10
-
90
-
-
84869807785
-
OCT4 positively regulates Survivin expression to promote cancer cell proliferation and leads to poor prognosis in esophageal squamous cell carcinoma
-
1:CAS:528:DC%2BC38XhvVags7%2FE 3504152 23185410 10.1371/journal.pone. 0049693
-
Li C, Yan Y, Ji W, Bao L, Qian H, Chen L, Wu M, Chen H, Li Z, Su C (2012) OCT4 positively regulates Survivin expression to promote cancer cell proliferation and leads to poor prognosis in esophageal squamous cell carcinoma. PLoS One 7:e49693
-
(2012)
PLoS One
, vol.7
, pp. 49693
-
-
Li, C.1
Yan, Y.2
Ji, W.3
Bao, L.4
Qian, H.5
Chen, L.6
Wu, M.7
Chen, H.8
Li, Z.9
Su, C.10
-
91
-
-
84859108713
-
Role of the stemness factors SOX2, OCT3/4, and NANOG in gastric carcinoma
-
1:CAS:528:DC%2BC38Xks1Squ74%3D 21227461 10.1016/j.jss.2010.11.903
-
Matsuoka J, Yashiro M, Sakurai K, Kubo N, Tanaka H, Muguruma K, Sawada T, Ohira M, Hirakawa K (2012) Role of the stemness factors SOX2, OCT3/4, and NANOG in gastric carcinoma. J Surg Res 174:130-135
-
(2012)
J Surg Res
, vol.174
, pp. 130-135
-
-
Matsuoka, J.1
Yashiro, M.2
Sakurai, K.3
Kubo, N.4
Tanaka, H.5
Muguruma, K.6
Sawada, T.7
Ohira, M.8
Hirakawa, K.9
-
92
-
-
84864922025
-
Targeted silencing of the oncogenic transcription factor SOX2 in breast cancer
-
1:CAS:528:DC%2BC38XhtF2rsLvF 3413152 22561374 10.1093/nar/gks360
-
Stolzenburg S, Rots MG, Beltran AS, Rivenbark AG, Yuan X, Qian H, Strahl BD, Blancafort P (2012) Targeted silencing of the oncogenic transcription factor SOX2 in breast cancer. Nucleic Acids Res 40:6725-6740
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 6725-6740
-
-
Stolzenburg, S.1
Rots, M.G.2
Beltran, A.S.3
Rivenbark, A.G.4
Yuan, X.5
Qian, H.6
Strahl, B.D.7
Blancafort, P.8
-
93
-
-
27844461512
-
Epithelial-mesenchymal transition in development and cancer: Role of phosphatidylinositol 3′ kinase/AKT pathways
-
1:CAS:528:DC%2BD2MXht1Wis7vE 16288291 10.1038/sj.onc.1209091
-
Larue L, Bellacosa A (2005) Epithelial-mesenchymal transition in development and cancer: role of phosphatidylinositol 3′ kinase/AKT pathways. Oncogene 24:7443-7454
-
(2005)
Oncogene
, vol.24
, pp. 7443-7454
-
-
Larue, L.1
Bellacosa, A.2
-
94
-
-
79953276254
-
SnapShot: The epithelial-mesenchymal transition
-
Sleeman JP, Thiery JP (2011) SnapShot: the epithelial-mesenchymal transition. Cell 145(162):e161
-
(2011)
Cell
, vol.145
, Issue.162
, pp. 161
-
-
Sleeman, J.P.1
Thiery, J.P.2
-
95
-
-
43049103824
-
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
-
1:CAS:528:DC%2BD1cXltl2is7c%3D 18376396 10.1038/ncb1722
-
Gregory PA, Bert AG, Paterson EL, Barry SC, Tsykin A, Farshid G, Vadas MA, Khew-Goodall Y, Goodall GJ (2008) The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol 10:593-601
-
(2008)
Nat Cell Biol
, vol.10
, pp. 593-601
-
-
Gregory, P.A.1
Bert, A.G.2
Paterson, E.L.3
Barry, S.C.4
Tsykin, A.5
Farshid, G.6
Vadas, M.A.7
Khew-Goodall, Y.8
Goodall, G.J.9
-
96
-
-
84855729906
-
A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial-mesenchymal transition
-
1:CAS:528:DC%2BC3MXhsVeit7jP 3206336 22024162 10.1083/jcb.201103097
-
Kim NH, Kim HS, Li XY, Lee I, Choi HS, Kang SE, Cha SY, Ryu JK, Yoon D, Fearon ER et al (2011) A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial-mesenchymal transition. J Cell Biol 195:417-433
-
(2011)
J Cell Biol
, vol.195
, pp. 417-433
-
-
Kim, N.H.1
Kim, H.S.2
Li, X.Y.3
Lee, I.4
Choi, H.S.5
Kang, S.E.6
Cha, S.Y.7
Ryu, J.K.8
Yoon, D.9
Fearon, E.R.10
|