메뉴 건너뛰기




Volumn 4, Issue 6, 2012, Pages 377-385

SOX2 redirects the developmental fate of the intestinal epithelium toward a premature gastric phenotype

Author keywords

Cdx2; gut development; Sox2

Indexed keywords

AQUAPORIN; TRANSCRIPTION FACTOR CDX2; TRANSCRIPTION FACTOR SOX2; TRANSCRIPTOME;

EID: 84871778678     PISSN: 16742788     EISSN: 17594685     Source Type: Journal    
DOI: 10.1093/jmcb/mjs030     Document Type: Article
Times cited : (45)

References (44)
  • 2
    • 0028879331 scopus 로고
    • Expression of Cdx-2 in the mouse embryo and placenta: Possible role in patterning of the extra-embryonic membranes
    • Beck, F., Erler, T., Russell, A., et al. (1995). Expression of Cdx-2 in the mouse embryo and placenta: possible role in patterning of the extra-embryonic membranes. Dev. Dyn. 204, 219-227.
    • (1995) Dev. Dyn. , vol.204 , pp. 219-227
    • Beck, F.1    Erler, T.2    Russell, A.3
  • 3
    • 53249125860 scopus 로고    scopus 로고
    • Multiple regulatory regions control the complex expression pattern of the mouse Cdx2 homeobox gene
    • 1247.e1-1247.e3
    • Benahmed, F., Gross, I., Gaunt, S.J., et al. (2008). Multiple regulatory regions control the complex expression pattern of the mouse Cdx2 homeobox gene. Gastroenterology 135, 1238-1247, 1247.e1-1247.e3.
    • (2008) Gastroenterology , vol.135 , pp. 1238-1247
    • Benahmed, F.1    Gross, I.2    Gaunt, S.J.3
  • 4
    • 0030937750 scopus 로고    scopus 로고
    • Homeosis and intestinal tumours in Cdx2 mutant mice
    • DOI 10.1038/386084a0
    • Chawengsaksophak, K., James, R., Hammond, V.E., et al. (1997). Homeosis and intestinal tumours in Cdx2 mutant mice. Nature 386, 84-87. (Pubitemid 27130925)
    • (1997) Nature , vol.386 , Issue.6620 , pp. 84-87
    • Chawiengsaksophak, K.1    James, R.2    Hammond, V.E.3    Kontgen, F.4    Beck, F.5
  • 6
    • 55049118409 scopus 로고    scopus 로고
    • Diverse adult stem cells share specific higher-order patterns of gene expression
    • Doherty, J.M., Geske, M.J., Stappenbeck, T.S., et al. (2008). Diverse adult stem cells share specific higher-order patterns of gene expression. Stem Cells 26, 2124-2130.
    • (2008) Stem Cells , vol.26 , pp. 2124-2130
    • Doherty, J.M.1    Geske, M.J.2    Stappenbeck, T.S.3
  • 7
    • 79957600785 scopus 로고    scopus 로고
    • Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes
    • Engelen, E., Akinci, U., Bryne, J.C., et al. (2011). Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes. Nat. Genet. 43, 607-611.
    • (2011) Nat. Genet. , vol.43 , pp. 607-611
    • Engelen, E.1    Akinci, U.2    Bryne, J.C.3
  • 8
    • 70349559758 scopus 로고    scopus 로고
    • Hippocampal development and neural stem cell maintenance require Sox2-dependent regulation of Shh
    • Favaro, R., Valotta, M., Ferri, A.L., et al. (2009). Hippocampal development and neural stem cell maintenance require Sox2-dependent regulation of Shh. Nat. Neurosci. 12, 1248-1256.
    • (2009) Nat. Neurosci. , vol.12 , pp. 1248-1256
    • Favaro, R.1    Valotta, M.2    Ferri, A.L.3
  • 9
    • 35648969554 scopus 로고    scopus 로고
    • Wnt/β-catenin is essential for intestinal homeostasis and maintenance of intestinal stem cells
    • DOI 10.1128/MCB.01034-07
    • Fevr, T., Robine, S., Louvard, D., et al. (2007). Wnt/beta-catenin is essential for intestinal homeostasis and maintenance of intestinal stem cells. Mol. Cell. Biol. 27, 7551-7559. (Pubitemid 350033660)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.21 , pp. 7551-7559
    • Fevr, T.1    Robine, S.2    Louvard, D.3    Huelsken, J.4
  • 10
    • 77953952170 scopus 로고    scopus 로고
    • Cdx2 regulates endo-lysosomal function and epithelial cell polarity
    • Gao, N., and Kaestner, K.H. (2010). Cdx2 regulates endo-lysosomal function and epithelial cell polarity. Genes Dev. 24, 1295-1305.
    • (2010) Genes Dev. , vol.24 , pp. 1295-1305
    • Gao, N.1    Kaestner, K.H.2
  • 11
    • 64549114508 scopus 로고    scopus 로고
    • Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2
    • Gao, N., White, P., and Kaestner, K.H. (2009). Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2. Dev. Cell 16, 588-599.
    • (2009) Dev. Cell , vol.16 , pp. 588-599
    • Gao, N.1    White, P.2    Kaestner, K.H.3
  • 12
    • 42649142250 scopus 로고    scopus 로고
    • Sox2 is important for two crucial processes in lung development: Branching morphogenesis and epithelial cell differentiation
    • Gontan, C., de Munck, A., Vermeij, M., et al. (2008). Sox2 is important for two crucial processes in lung development: branching morphogenesis and epithelial cell differentiation. Dev. Biol. 317, 296-309.
    • (2008) Dev. Biol. , vol.317 , pp. 296-309
    • Gontan, C.1    De Munck, A.2    Vermeij, M.3
  • 13
    • 65249126965 scopus 로고    scopus 로고
    • Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors
    • Gontan, C., Güttler, T., Engelen, E., et al. (2009). Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors. J. Cell Biol. 185, 27-34.
    • (2009) J. Cell Biol. , vol.185 , pp. 27-34
    • Gontan, C.1    Güttler, T.2    Engelen, E.3
  • 15
    • 0036829210 scopus 로고    scopus 로고
    • CDX2 regulates liver intestine-cadherin expression in normal and malignant colon epithelium and intestinal metaplasia
    • Hinoi, T., Lucas, P.C., Kuick, R., et al. (2002). CDX2 regulates liver intestine-cadherin expression in normal and malignant colon epithelium and intestinal metaplasia. Gastroenterology 123, 1565-1577. (Pubitemid 35231656)
    • (2002) Gastroenterology , vol.123 , Issue.5 , pp. 1565-1577
    • Hinoi, T.1    Lucas, P.C.2    Kuick, R.3    Hanash, S.4    Cho, K.R.5    Fearon, E.R.6
  • 16
    • 84863072227 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 2a plays a critical role in the formation of alveoli and surfactant
    • Huang, Y., Buscop-van Kempen, M., Boerema-de Munck, A., et al. (2012). Hypoxia-inducible factor 2a plays a critical role in the formation of alveoli and surfactant. Am. J. Respir. Cell Mol. Biol. 46, 224-232.
    • (2012) Am. J. Respir. Cell Mol. Biol. , vol.46 , pp. 224-232
    • Huang, Y.1    Buscop-Van Kempen, M.2    Boerema-De Munck, A.3
  • 17
    • 0031758247 scopus 로고    scopus 로고
    • Region-specific expression of chicken Sox2 in the developing gut and lung epithelium: Regulation by epithelial-mesenchymal interactions
    • DOI 10.1002/(SICI)1097-0177(199812)213:4<464::AID-AJA11>3.0.CO;2-Z
    • Ishii, Y., Rex, M., Scotting, P.J., et al. (1998). Region-specific expression of chicken Sox2 in the developing gut and lung epithelium: regulation by epi-thelial-mesenchymal interactions. Dev. Dyn. 213, 464-475. (Pubitemid 28546125)
    • (1998) Developmental Dynamics , vol.213 , Issue.4 , pp. 464-475
    • Ishii, Y.1    Rex, M.2    Scotting, P.J.3    Yasugi, S.4
  • 18
    • 39149130361 scopus 로고    scopus 로고
    • Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming
    • DOI 10.1016/j.cell.2008.01.015, PII S0092867408001153
    • Jaenisch, R., and Young, R. (2008). Stem cells, the molecular circuitry of plur-ipotency and nuclear reprogramming. Cell 132, 567-582. (Pubitemid 351253686)
    • (2008) Cell , vol.132 , Issue.4 , pp. 567-582
    • Jaenisch, R.1    Young, R.2
  • 19
    • 0025906410 scopus 로고
    • Homeobox gene expression in the intestinal epithelium of adult mice
    • James, R., and Kazenwadel, J. (1991). Homeobox gene expression in the intestinal epithelium of adult mice. J. Biol. Chem. 266, 3246-3251. (Pubitemid 21909201)
    • (1991) Journal of Biological Chemistry , vol.266 , Issue.5 , pp. 3246-3251
    • James, R.1    Kazenwadel, J.2
  • 20
    • 0028243649 scopus 로고
    • Structure of the murine homeo-box gene cdx-2. Expression in embryonic and adult intestinal epithelium
    • James, R., Erler, T., and Kazenwadel, J. (1994). Structure of the murine homeo-box gene cdx-2. Expression in embryonic and adult intestinal epithelium. J. Biol. Chem. 269, 15229-15237.
    • (1994) J. Biol. Chem. , vol.269 , pp. 15229-15237
    • James, R.1    Erler, T.2    Kazenwadel, J.3
  • 21
    • 76549093805 scopus 로고    scopus 로고
    • SOX-partner code for cell specification: Regulatory target selection and underlying molecular mechanisms
    • Kondoh, H., and Kamachi, Y. (2010). SOX-partner code for cell specification: regulatory target selection and underlying molecular mechanisms. Int. J. Biochem. Cell Biol. 42, 391-399.
    • (2010) Int. J. Biochem. Cell Biol. , vol.42 , pp. 391-399
    • Kondoh, H.1    Kamachi, Y.2
  • 22
    • 73949105534 scopus 로고    scopus 로고
    • Interactions between SOX factors and Wnt/beta-catenin signaling in development and disease
    • Kormish, J.D., Sinner, D., and Zorn, A.M. (2010). Interactions between SOX factors and Wnt/beta-catenin signaling in development and disease. Dev. Dyn. 239, 56-68.
    • (2010) Dev. Dyn. , vol.239 , pp. 56-68
    • Kormish, J.D.1    Sinner, D.2    Zorn, A.M.3
  • 23
    • 0034010701 scopus 로고    scopus 로고
    • Extensive gastric heterotopia of the small intestine resulting in massive gastrointestinal bleeding, bowel perforation, and death: Report a case and review of the literature
    • DOI 10.1007/s100249910036
    • Lambert, M.P., Heller, D.S., and Bethel, C. (2000). Extensive gastric heterotopia of the small intestine resulting in massive gastrointestinal bleeding, bowel perforation, and death: report of a case and review of the literature. Pediatr. Dev. Pathol. 3, 277-280. (Pubitemid 30232854)
    • (2000) Pediatric and Developmental Pathology , vol.3 , Issue.3 , pp. 277-280
    • Lambert, M.P.1    Heller, D.S.2    Bethel, C.3
  • 24
    • 0034162046 scopus 로고    scopus 로고
    • Developmental biology of gastrin and somatostatin cells in the antropyloric mucosa of the stomach
    • Larsson, L.I. (2000). Developmental biology of gastrin and somatostatin cells in the antropyloric mucosa of the stomach. Microsc. Res. Tech. 48, 272-281.
    • (2000) Microsc. Res. Tech. , vol.48 , pp. 272-281
    • Larsson, L.I.1
  • 25
    • 0035710746 scopus 로고    scopus 로고
    • -ΔΔCT method
    • DOI 10.1006/meth.2001.1262
    • Livak, K.J., and Schmittgen, T.D. (2001). Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)). Methods 25, 402-408. (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 27
    • 79551684935 scopus 로고    scopus 로고
    • Sox2 expression is maintained while gastric phenotype is completely lost in Cdx2-induced intestinal metaplastic mucosa
    • Mutoh, H., Sashikawa, M., and Sugano, K. (2011). Sox2 expression is maintained while gastric phenotype is completely lost in Cdx2-induced intestinal metaplastic mucosa. Differentiation 81, 92-98.
    • (2011) Differentiation , vol.81 , pp. 92-98
    • Mutoh, H.1    Sashikawa, M.2    Sugano, K.3
  • 28
    • 70349325798 scopus 로고    scopus 로고
    • Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors
    • Nishiyama, A., Xin, L., Sharov, A.A., et al. (2009). Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors. Cell Stem Cell 5, 420-433.
    • (2009) Cell Stem Cell , vol.5 , pp. 420-433
    • Nishiyama, A.1    Xin, L.2    Sharov, A.A.3
  • 29
    • 39649119479 scopus 로고    scopus 로고
    • Aberrant expression of SOX2 upregulates MUC5AC gastric foveolar mucin in mucinous cancers of the colorectum and related lesions
    • DOI 10.1002/ijc.23225
    • Park, E.T., Gum, J.R., Kakar, S., et al. (2008). Aberrant expression of SOX2 upre-gulates MUC5AC gastric foveolar mucin in mucinous cancers of the colorec-tum and related lesions. Int. J. Cancer 122, 1253-1260. (Pubitemid 351287224)
    • (2008) International Journal of Cancer , vol.122 , Issue.6 , pp. 1253-1260
    • Park, E.T.1    Gum, J.R.2    Kakar, S.3    Kwon, S.W.4    Deng, G.5    Kim, Y.S.6
  • 31
    • 69549090537 scopus 로고    scopus 로고
    • Multiple roles for Sox2 in the developing and adult mouse trachea
    • Que, J., Luo, X., Schwartz, R.J., et al. (2009). Multiple roles for Sox2 in the developing and adult mouse trachea. Development 136, 1899-1907.
    • (2009) Development , vol.136 , pp. 1899-1907
    • Que, J.1    Luo, X.2    Schwartz, R.J.3
  • 32
    • 48849098709 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factors in normal human lung development
    • Rajatapiti, P., van der Horst, I.W., de Rooij, J.D., et al. (2008). Expression of hypoxia-inducible factors in normal human lung development. Pediatr. Dev. Pathol. 11, 193-199.
    • (2008) Pediatr. Dev. Pathol. , vol.11 , pp. 193-199
    • Rajatapiti, P.1    Van Der Horst, I.W.2    De Rooij, J.D.3
  • 33
    • 33846489141 scopus 로고    scopus 로고
    • The maturation of mucus-secreting gastric epithelial progenitors into digestive-enzyme secreting zymogenic cells requires Mist1
    • DOI 10.1242/dev.02700
    • Ramsey, V.G., Doherty, J.M., Chen, C.C., et al. (2007). The maturation of mucus-secreting gastric epithelial progenitors into digestive-enzyme secreting zymogenic cells requires Mist1. Development 134, 211-222. (Pubitemid 46152721)
    • (2007) Development , vol.134 , Issue.1 , pp. 211-222
    • Ramsey, V.G.1    Doherty, J.M.2    Chen, C.C.3    Stappenbeck, T.S.4    Konieczny, S.F.5    Mills, J.C.6
  • 34
    • 67449084190 scopus 로고    scopus 로고
    • Generation of a tightly regulated doxycycline-inducible model for studying mouse intestinal biology
    • Roth, S., Franken, P., van Veelen, W., et al. (2009). Generation of a tightly regulated doxycycline-inducible model for studying mouse intestinal biology. Genesis 47, 7-13.
    • (2009) Genesis , vol.47 , pp. 7-13
    • Roth, S.1    Franken, P.2    Van Veelen, W.3
  • 35
    • 0034068788 scopus 로고    scopus 로고
    • The pathogenesis of duodenal gastric metaplasia: The role of local goblet cell transformation
    • DOI 10.1136/gut.46.5.632
    • Shaoul, R., Marcon, P., Okada, Y., et al. (2000). The pathogenesis of duodenal gastric metaplasia: the role of local goblet cell transformation. Gut 46, 632-638. (Pubitemid 30305779)
    • (2000) Gut , vol.46 , Issue.5 , pp. 632-638
    • Shaoul, R.1    Marcon, P.2    Okada, Y.3    Cutz, E.4    Forstner, G.5
  • 36
    • 58149262961 scopus 로고    scopus 로고
    • Transcriptional dynamics of endodermal organ formation
    • Sherwood, R.I., Chen, T.Y., and Melton, D.A. (2009). Transcriptional dynamics of endodermal organ formation. Dev. Dyn. 238, 29-42.
    • (2009) Dev. Dyn. , vol.238 , pp. 29-42
    • Sherwood, R.I.1    Chen, T.Y.2    Melton, D.A.3
  • 37
    • 84855464779 scopus 로고    scopus 로고
    • Cdx2 determines the fate of postnatal intestinal endoderm
    • Stringer, E.J., Duluc, I., Saandi, T., et al. (2012). Cdx2 determines the fate of postnatal intestinal endoderm. Development 139, 465-474.
    • (2012) Development , vol.139 , pp. 465-474
    • Stringer, E.J.1    Duluc, I.2    Saandi, T.3
  • 38
    • 33745147915 scopus 로고    scopus 로고
    • SOX2 is a dose-dependent regulator of retinal neural progenitor competence
    • Taranova, O.V., Magness, S.T., Fagan, B.M., et al. (2006). SOX2 is a dose-dependent regulator of retinal neural progenitor competence. Genes Dev. 20, 1187-1202.
    • (2006) Genes Dev. , vol.20 , pp. 1187-1202
    • Taranova, O.V.1    Magness, S.T.2    Fagan, B.M.3
  • 39
    • 77956988273 scopus 로고    scopus 로고
    • TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions
    • Verzi, M.P., Hatzis, P., Sulahian, R., et al. (2010). TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions. Proc. Natl Acad. Sci. USA 107, 15157-15162.
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 15157-15162
    • Verzi, M.P.1    Hatzis, P.2    Sulahian, R.3
  • 41
    • 0034093614 scopus 로고    scopus 로고
    • Early mouse endoderm is patterned by soluble factors from adjacent germ layers
    • Wells, J.M., and Melton, D.A. (2000). Early mouse endoderm is patterned by soluble factors from adjacent germ layers. Development 127, 1563-1572. (Pubitemid 30234914)
    • (2000) Development , vol.127 , Issue.8 , pp. 1563-1572
    • Wells, J.M.1    Melton, D.A.2
  • 42
    • 33646162880 scopus 로고    scopus 로고
    • Mutations in SOX2 cause anophthalmia-esophageal-genital (AEG) syndrome
    • Williamson, K.A., Hever, A.M., Rainger, J., et al. (2006). Mutations in SOX2 cause anophthalmia-esophageal-genital (AEG) syndrome. Hum. Mol. Genet. 15, 1413-1422.
    • (2006) Hum. Mol. Genet. , vol.15 , pp. 1413-1422
    • Williamson, K.A.1    Hever, A.M.2    Rainger, J.3
  • 44
    • 70350225535 scopus 로고    scopus 로고
    • Vertebrate endoderm development and organ formation
    • Zorn, A.M., and Wells, J.M. (2009). Vertebrate endoderm development and organ formation. Annu. Rev. Cell Dev. Biol. 25, 221-251.
    • (2009) Annu. Rev. Cell Dev. Biol. , vol.25 , pp. 221-251
    • Zorn, A.M.1    Wells, J.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.