Silencing SOX2 induced mesenchymal-epithelial transition and its expression predicts liver and lymph node metastasis of CRC patients

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Han, Xu ^a   Fang, Xuefeng ^d   Lou, Xiaoyan ^a   Hua, Dasong ^a   Ding, Wenchao ^a   Foltz, Gregory ^b   Hood, Leroy ^c   Yuan, Ying ^d   Lin, Biaoyang ^a,b,e  

^a ZHEJIANG UNIVERSITY   (China)

^b SWEDISH MEDICAL CENTER   (United States)

^c INSTITUTE FOR SYSTEMS BIOLOGY   (United States)

^d THE SECOND AFFILIATED HOSPITAL OF ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^e UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE A; TRANSCRIPTION FACTOR SOX2; UVOMORULIN; VIMENTIN; WNT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CANCER PATIENT; CANCER PROGNOSIS; CARCINOGENESIS; CELL INVASION; CELL MIGRATION; CLINICAL ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; ENZYME ACTIVITY; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LIVER METASTASIS; LYMPH NODE METASTASIS; MOUSE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ANIMALS; BETA CATENIN; CELL LINE, TUMOR; CELL MOVEMENT; COLORECTAL NEOPLASMS; DOWN-REGULATION; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HUMANS; LIVER NEOPLASMS; LYMPHATIC METASTASIS; LYMPHOID ENHANCER-BINDING FACTOR 1; MATRIX METALLOPROTEINASE 2; MICE; NEOPLASM INVASIVENESS; SIGNAL TRANSDUCTION; SOXB1 TRANSCRIPTION FACTORS; TCF TRANSCRIPTION FACTORS;

EID: 84865106429     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0041335     Document Type: Article

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