Zfp148 Deficiency Causes Lung Maturation Defects and Lethality in Newborn Mice That Are Rescued by Deletion of p53 or Antioxidant Treatment

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Sayin, Volkan I ^a,b   Nilton, Anna ^a   Ibrahim, Mohamed X ^b   Ågren, Pia ^a   Larsson, Erik ^a,b   Petit, Marleen M ^a,c   Hultén, Lillemor Mattsson ^a   Ståhlman, Marcus ^a   Johansson, Bengt R ^b   Bergo, Martin O ^b   Lindahl, Per ^a,b  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; BROXURIDINE; LUNG SURFACTANT; MESSENGER RNA; PROTEIN P53; REGULATOR PROTEIN; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN 148;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CYCLE ARREST; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRESS; CONTROLLED STUDY; DEVELOPMENTAL STAGE; FEMALE; GENE DELETION; GENE EXPRESSION REGULATION; GENOTYPE; GROWTH RETARDATION; LETHALITY; LIFESPAN; LUNG ALVEOLUS CELL; LUNG DEVELOPMENT; LUNG MALFORMATION; MALE; MOUSE; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; PRENATAL PERIOD; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATOR GENE; RESPIRATORY DISTRESS; ZINC FINGER PROTEIN 148 GENE;

ANIMALS; ANIMALS, NEWBORN; ANTIOXIDANTS; APOPTOSIS; BLOTTING, SOUTHERN; BLOTTING, WESTERN; CELL CYCLE; CELL PROLIFERATION; CELLS, CULTURED; DNA-BINDING PROTEINS; EMBRYO, MAMMALIAN; FEMALE; FIBROBLASTS; GENE DELETION; GENES, LETHAL; IMMUNOENZYME TECHNIQUES; LUNG; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OXIDATIVE STRESS; REAL-TIME POLYMERASE CHAIN REACTION; RESPIRATORY TRACT DISEASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84873529532     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0055720     Document Type: Article

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