β-hairpin-mediated formation of structurally distinct multimers of neurotoxic prion peptides

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Gill, Andrew C ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLLEUCYLLYSYLHISTIDYLVALYLALANYLGLYCYLALANYLALANYLALANYLALANYLGLYCYLALANYLVALYLVALINE AMIDE; ACETYLLEUCYLLYSYLHISTIDYLVALYLALANYLGLYCYLALANYLALANYLVALYLALANYLVALYLVALINE AMIDE; ACETYLLYSYLTHREONYLASPARAGINYLLEUCYLLYSYLHISTIDYLVALYLALANYLGLYCYLALANYLALANYLALANYLALANYLGLYCYLALANYLVALYLVALYLGLYCYLGLYCYLLEUCYLGLYCINE AMIDE; ACETYLLYSYLTHREONYLASPARAGINYLLEUCYLLYSYLHISTIDYLVALYLALANYLGLYCYLALANYLALANYLVALYLALANYLGLYCYLALANYLVALYLVALYLGLYCYLGLYCLLEUCYLGLYCINE AMIDE; AMYLOID; BETA HAIRPIN PROTEIN; MONOMER; OLIGOMER; PRION PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CLUSTER ANALYSIS; CONTROLLED STUDY; CROSS LINKING; HYDROGEN BOND; MOLECULAR DYNAMICS; MONTE CARLO METHOD; MUTATIONAL ANALYSIS; NEUROTOXICITY; NONHUMAN; PATHOGENESIS; PREVALENCE; PRION DISEASE; PROTEIN ASSEMBLY; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN MISFOLDING; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; THERMODYNAMICS; THERMOSTABILITY;

AMINO ACID SEQUENCE; AMYLOID; COMPUTER SIMULATION; HUMANS; HYDROGEN BONDING; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MONTE CARLO METHOD; MUTATION; PEPTIDES; PRIONS; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; PRPC PROTEINS; THERMODYNAMICS;

EID: 84900311453     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0087354     Document Type: Article

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