β-hairpin conformation of fibrillogenic peptides: Structure and α-β transition mechanism revealed by molecular dynamics simulations

Proteins: Structure, Function and Genetics

Volumn 57, Issue 1, 2004, Pages 198-204

  Daidone, Isabella ^a   Simona, Fabio ^b   Roccatano, Danilo ^c   Broglia, Ricardo A ^d   Tiana, Guido ^d   Colombo, Giorgio ^b   Di Nola, Alfredo ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b CNR   (Italy)

^c JACOBS UNIVERSITY BREMEN   (Germany)

^d UNIVERSITY OF MILAN   (Italy)

Author keywords

Conformational transition; A peptide; Amyloid diseases; Misfolding; Prion protein

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; AMYLOID BETA PROTEIN[12-28]; PRION PROTEIN; TRIFLUOROETHANOL; UNCLASSIFIED DRUG; WATER;

ALPHA HELIX; ALZHEIMER DISEASE; AMYLOIDOSIS; ARTICLE; CONFORMATIONAL TRANSITION; HYDROPHOBICITY; MOLECULAR DYNAMICS; PH; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE;

ANIMALS; COMPUTER SIMULATION; CRICETINAE; MESOCRICETUS; MODELS, CHEMICAL; PEPTIDE FRAGMENTS; PRIONS; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; SOFTWARE; SOLVENTS; TIME FACTORS; WATER;

EID: 4444267407     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/prot.20178     Document Type: Article

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