C-terminal turn stability determines assembly differences between Aβ40 and Aβ42

Journal of Molecular Biology

Volumn 425, Issue 2, 2013, Pages 292-308

  Roychaudhuri, Robin ^a   Yang, Mingfeng ^a   Deshpande, Atul ^b,c   Cole, Gregory M ^b,c   Frautschy, Sally ^b,c   Lomakin, Aleksey ^d   Benedek, George B ^d   Teplow, David B ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c VA GREATER LOS ANGELES HEALTHCARE SYSTEM   (United States)

^d Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

Alzheimer's disease; amyloid protein; hairpin

Indexed keywords

ALANINE; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; GLYCINE; ISOLEUCINE; VALINE;

ALZHEIMER DISEASE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CIRCULAR DICHROISM; CONTROLLED STUDY; CYTOTOXICITY; HYDROGEN BOND; HYDROPHOBICITY; MOLECULAR DYNAMICS; NEUROTOXICITY; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN CONFORMATION; PROTEIN FOLDING; RAT; SYNTHESIS;

EID: 84872113583     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2012.11.006     Document Type: Article

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