Mutational analysis of the structural organization of polyglutamine aggregates

Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 26, 2002, Pages 17014-17019

  Thakur, Ashwani K ^a   Wetzel, Ronald ^a  

^a UNIVERSITY OF TENNESSEE MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; PEPTIDE; POLYGLUTAMINE; PROTEIN ANTIBODY;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; HUMAN; HUNTINGTON CHOREA; MUTATIONAL ANALYSIS; NEUROPATHOLOGY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN FOLDING;

AMINO ACID SEQUENCE; KINETICS; MUTATION; PEPTIDES; PROTEIN FOLDING;

EID: 0037168642     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.252523899     Document Type: Article

References (37)

1. Karlin, S. & Burge, C. (1996) Proc. Natl. Acad. Sci. USA 93, 1560-1565.
2. Cummings, C. J. & Zoghbi, H. Y. (2000) Hum. Mol. Genet. 9, 909-916.
3. Myers, R. H., Marans, K. S. & MacDonald, M. E. (1998) in Genetic Instabilities and Hereditary Neurological Diseases, eds. Wells, R. D. & Warren, S. T. (Academic, San Diego), pp. 301-323.
4. Davies, S. W., Turmaine, M., Cozens, B. A., DiFiglia, M., Sharp, A. H., Ross, C. A., Scherzinger, E., Wanker, E. E., Mangiarini, L. & Bates, G. P. (1997) Cell 90, 537-548.
5. Paulson, H. L., Perez, M. K., Trottier, Y., Trojanowski, J. Q., Subramony, S. H., Das, S. S., Vig, P., Mandel, J. L., Fischbeck, K. H. & Pittman, R. N. (1997) Neuron 19, 333-344.
6. DiFiglia, M., Sapp, E., Chase, K. O., Davies, S. W., Bates, G. P., Vonsattel, J. P. & Aronin, N. (1997) Science 277, 1990-1993.
7. Tobin, A. J. & Signer, E. R. (2000) Trends Cell Biol. 10, 531-536.
8. Yang, W., Dunlap, J. R., Andrews, R. B. & Wetzel, R. (2002) Hum. Mol. Genet. 11, 2905-2917.
9. Scherzinger, E., Lurz, R., Turmaine, M., Mangiarini, L., Hollenbach, B., Hasenbank, R., Bates, G. P., Davies, S. W., Lehrach, H. & Wanker, E. E. (1997) Cell 90, 549-558.
10. Chen, S., Berthelier, V., Yang, W. & Wetzel, R. (2001) J. Mol. Biol. 311, 173-182.
11. Chen, S., Ferrone, F. & Wetzel, R. (2002) Proc. Natl. Acad. Sci. USA 99, 11884-11889.
12. Masino, L., Kelly, G., Leonard, K., Trottier, Y. & Pastore, A. (2002) FEBS Lett. 513, 267-272.
13. Bennett, M. J., Huey-Tubman, K. E., Herr, A. B., West, A. P., Ross, S. A. & Bjorkman, P. J. (2002) Proc. Natl. Acad. Sci. USA 99, 11634-11639.
14. Chen, S., Berthelier, V., Hamilton, J. B., O'Nuallain, B. & Wetzel, R. (2002) Biochemistry 41, 7391-7399.
15. Scherzinger, E., Sittler, A., Schweiger, K., Heiser, V., Lurz, R., Hasenbank, R., Bates, G. P., Lehrach, H. & Wanker, E. E. (1999) Proc. Natl. Acad. Sci. USA 96, 4604-4609.
16. Harper, J. D. & Lansbury, P. T., Jr. (1997) Annu. Rev. Biochem. 66, 385-407.
17. Inouye, H., Fraser, P. E. & Kirschner, D. A. (1993) Biophys. J. 64, 502-519.
18. Kheterpal, I., Williams, A., Murphy, C., Bledsoe, B. & Wetzel, R. (2001) Biochemistry 40, 11757-11767.
19. Egnaczyk, G. F., Greis, K. D., Stimson, E. R. & Maggio, J. E. (2001) Biochemistry 40, 11706-11714.
20. Kheterpal, I., Zhou, S., Cook, K. D. & Wetzel, R. (2000) Proc. Natl. Acad. Sci. USA 97, 13597-13601.
21. Esler, W. P., Stimson, E. R., Ghilardi, J. R., Lu, Y. A., Felix, A. M., Vinters, H. V., Mantyh, P. W., Lee, J. P. & Maggio, J. E. (1996) Biochemistry 35, 13914-13921.
22. Torok, M., Milton, S., Kayed, R., Wu, P., McIntire, T., Glabe, C. C. & Langen, R. (2002) J. Biol. Chem. 277, 40810-40815.
23. Venkatraman, J., Shankaramma, S. C. & Balaram, P. (2001) Chem. Rev. 101, 3131-3152.
24. Perutz, M. F., Finch, J. T., Berriman, J. & Lesk, A. (2002) Proc. Natl. Acad. Sci. USA 99, 5591-5595.
25. Wood, S. J., Wetzel, R., Martin, J. D. & Hurle, M. R. (1995) Biochemistry 34, 724-730.
26. Wigley, W. C., Corboy, M. J., Cutler, T. D., Thibodeau, P. H., Oldan, J., Lee, M. G., Rizo, J., Hunt, J. F. & Thomas, P. J. (2002) Nat. Struct. Biol. 9, 381-388.
27. Moriarty, D. F. & Raleigh, D. P. (1999) Biochemistry 38, 1811-1818.
28. Morimoto, A., Irie, K., Murakami, K., Ohigashi, H., Shindo, M., Nagao, M., Shimizu, T. & Shirasawa, T. (2002) Biochem. Biophys. Res. Commun. 295, 306-311.
29. Chen, S. & Wetzel, R. (2001) Protein Sci. 10, 887-891.
30. O'Nuallain, B. & Wetzel, R. (2002) Proc. Natl. Acad. Sci. USA 99, 1485-1490.
31. Stanger, H. E., Syud, F. A., Espinosa, J. F., Giriat, I., Muir, T. & Gellman, S. H. (2001) Proc. Natl. Acad. Sci. USA 98, 12015-12020.
32. Harper, J. D., Wong, S. S., Lieber, C. M. & Lansbury, P. T. (1997) Chem. Biol. 4, 119-125.
33. Walsh, D. M., Lomakin, A., Benedek, G. B., Condron, M. M. & Teplow, D. B. (1997) J. Biol. Chem. 272, 22364-22372.
34. Ferrone, F. (1999) Methods Enzymol. 309, 256-274.
35. Starikov, E. B., Lehrach, H. & Wanker, E. E. (1999) J. Biomol. Struct. Dyn. 17, 409-427.
36. Jenkins, J. & Pickersgill, R. (2001) Prog. Biophys. Mol. Biol. 77, 111-175.
37. Wetzel, R. (2002) Structure (London) 10, 1031-1036.