-
1
-
-
84880187571
-
Tau protein, the paired helical filament and Alzheimer's disease
-
Goedert M, Klug A, Crowther RA: Tau protein, the paired helical filament and Alzheimer's disease. J Alzheimers Dis 2006; 9: 195-207.
-
(2006)
J Alzheimers Dis
, vol.9
, pp. 195-207
-
-
Goedert, M.1
Klug, A.2
Crowther, R.A.3
-
2
-
-
46749113005
-
Tau-based treatment strategies in neurodegenerative diseases
-
Schneider A, Mandelkow E: Tau-based treatment strategies in neurodegenerative diseases. Neurotherapeutics 2008; 5: 443-457.
-
(2008)
Neurotherapeutics
, vol.5
, pp. 443-457
-
-
Schneider, A.1
Mandelkow, E.2
-
3
-
-
17944382037
-
Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP
-
Lewis J, Dickson DW, Lin WL, Chisholm L, Corral A, Jones G, Yen SH, Sahara N, Skipper L, Yager D, Eckman C, Hardy J, Hutton M, McGowan E: Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP. Science 2001; 293: 1487-1491.
-
(2001)
Science
, vol.293
, pp. 1487-1491
-
-
Lewis, J.1
Dickson, D.W.2
Lin, W.L.3
Chisholm, L.4
Corral, A.5
Jones, G.6
Yen, S.H.7
Sahara, N.8
Skipper, L.9
Yager, D.10
Eckman, C.11
Hardy, J.12
Hutton, M.13
McGowan, E.14
-
4
-
-
0034718571
-
Structure, microtubule interactions, and paired helical filament aggregation by tau mutants of frontotemporal dementias
-
Barghorn S, Zheng-Fischhofer Q, Ackmann M, Biernat J, von Bergen M, Mandelkow EM, Mandelkow E: Structure, microtubule interactions, and paired helical filament aggregation by tau mutants of frontotemporal dementias. Biochemistry 2000; 39: 11714-11721.
-
(2000)
Biochemistry
, vol.39
, pp. 11714-11721
-
-
Barghorn, S.1
Zheng-Fischhofer, Q.2
Ackmann, M.3
Biernat, J.4
Von Bergen, M.5
Mandelkow, E.M.6
Mandelkow, E.7
-
5
-
-
38549129613
-
The potential for beta-structure in the repeat domain of tau protein determines aggregation, synaptic decay, neuronal loss, and coassembly with endogenous Tau in inducible mouse models of tauopathy
-
Mocanu MM, Nissen A, Eckermann K, Khlistunova I, Biernat J, Drexler D, Petrova O, Schönig K, Bujard H, Mandelkow E, Zhou L, Rune G, Mandelkow EM: The potential for beta-structure in the repeat domain of tau protein determines aggregation, synaptic decay, neuronal loss, and coassembly with endogenous Tau in inducible mouse models of tauopathy. J Neurosci 2008; 28: 737-748.
-
(2008)
J Neurosci
, vol.28
, pp. 737-748
-
-
Mocanu, M.M.1
Nissen, A.2
Eckermann, K.3
Khlistunova, I.4
Biernat, J.5
Drexler, D.6
Petrova, O.7
Schönig, K.8
Bujard, H.9
Mandelkow, E.10
Zhou, L.11
Rune, G.12
Mandelkow, E.M.13
-
6
-
-
35748954923
-
The beta-propensity of Tau determines aggregation and synaptic loss in inducible mouse models of Alzheimer tauopathy
-
Eckermann K, Mocanu MM, Khlistunova I, Biernat J, Nissen A, Hofmann A, Schönig K, Bujard H, Haemisch, A, Mandelkow E, Zhou L, Rune G, Mandelkow EM: The beta-propensity of Tau determines aggregation and synaptic loss in inducible mouse models of Alzheimer tauopathy. J Biol Chem 2007; 282: 31755-31765.
-
(2007)
J Biol Chem
, vol.282
, pp. 31755-31765
-
-
Eckermann, K.1
Mocanu, M.M.2
Khlistunova, I.3
Biernat, J.4
Nissen, A.5
Hofmann, A.6
Schönig, K.7
Bujard, H.8
Haemisch, A.9
Mandelkow, E.10
Zhou, L.11
Rune, G.12
Mandelkow, E.M.13
-
7
-
-
0036956875
-
Studying gene function in eukaryotes by conditional gene inactivation
-
Gossen M, Bujard H: Studying gene function in eukaryotes by conditional gene inactivation. Annu Rev Genet 2002; 36: 153-173.
-
(2002)
Annu Rev Genet
, vol.36
, pp. 153-173
-
-
Gossen, M.1
Bujard, H.2
-
8
-
-
0029807527
-
Control of memory formation through regulated expression of a CaMKII transgene
-
Mayford M, Bach ME, Huang YY, Wang L, Hawkins RD, Kandel ER: Control of memory formation through regulated expression of a CaMKII transgene. Science 1996; 274: 1678-1683.
-
(1996)
Science
, vol.274
, pp. 1678-1683
-
-
Mayford, M.1
Bach, M.E.2
Huang, Y.Y.3
Wang, L.4
Hawkins, R.D.5
Kandel, E.R.6
-
9
-
-
0035930625
-
Mutations of tau protein in frontotemporal dementia promote aggregation of paired helical filaments by enhancing local betastructure
-
von Bergen M, Barghorn S, Li L, Marx A, Biernat J, Mandelkow EM, Mandelkow E: Mutations of tau protein in frontotemporal dementia promote aggregation of paired helical filaments by enhancing local betastructure. J Biol Chem 2001; 276: 48165-48174.
-
(2001)
J Biol Chem
, vol.276
, pp. 48165-48174
-
-
Von Bergen, M.1
Barghorn, S.2
Li, L.3
Marx, A.4
Biernat, J.5
Mandelkow, E.M.6
Mandelkow, E.7
-
10
-
-
0032938625
-
Assembly of paired helical filaments from mouse tau: Implications for the neurofibrillary pathology in transgenic mouse models for Alzheimer's disease
-
Kampers T, Pangalos M, Geerts H, Wiech H, Mandelkow E: Assembly of paired helical filaments from mouse tau: implications for the neurofibrillary pathology in transgenic mouse models for Alzheimer's disease. FEBS Lett 1999; 451: 39-44.
-
(1999)
FEBS Lett
, vol.451
, pp. 39-44
-
-
Kampers, T.1
Pangalos, M.2
Geerts, H.3
Wiech, H.4
Mandelkow, E.5
-
11
-
-
45749151056
-
Animal models of Alzheimer's disease and frontotemporal dementia
-
Götz J, Ittner LM: Animal models of Alzheimer's disease and frontotemporal dementia. Nat Rev Neurosci 2008; 9: 532-544.
-
(2008)
Nat Rev Neurosci
, vol.9
, pp. 532-544
-
-
Götz, J.1
Ittner, L.M.2
-
12
-
-
0041803006
-
Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms
-
Andorfer C, Kress Y, Espinoza M, de Silva R, Tucker KL, Barde YA, Duff K, Davies P: Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms. J Neurochem 2003; 86: 582-590.
-
(2003)
J Neurochem
, vol.86
, pp. 582-590
-
-
Andorfer, C.1
Kress, Y.2
Espinoza, M.3
De Silva, R.4
Tucker, K.L.5
Barde, Y.A.6
Duff, K.7
Davies, P.8
-
13
-
-
0025292866
-
A preparation of Alzheimer paired helical filaments that displays distinct tau proteins by polyacrylamide gel electrophoresis
-
Greenberg SG, Davies P: A preparation of Alzheimer paired helical filaments that displays distinct tau proteins by polyacrylamide gel electrophoresis. Proc Natl Acad Sci USA 1990; 87: 5827-5831.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 5827-5831
-
-
Greenberg, S.G.1
Davies, P.2
-
14
-
-
70349987102
-
Tau fragmentation, aggregation and clearance: The dual role of lysosomal processing
-
Wang YP, Martinez-Vincente M, Krüger U, Kaushik S, Wong E, Mandelkow EM, Cuervo AM, Mandelkow E: Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing. Human Molec Gen 2009; 18: 4153-4170.
-
(2009)
Human Molec Gen
, vol.18
, pp. 4153-4170
-
-
Wang, Y.P.1
Martinez-Vincente, M.2
Krüger, U.3
Kaushik, S.4
Wong, E.5
Mandelkow, E.M.6
Cuervo, A.M.7
Mandelkow, E.8
-
15
-
-
61349145507
-
Development of tau aggregation inhibitors for Alzheimer's disease
-
Bulic B, Pickhardt M, Schmidt B, Mandelkow EM, Waldmann H, Mandelkow E: Development of tau aggregation inhibitors for Alzheimer's disease. Angew Chem Int Ed Engl 2009; 48: 1740-1752.
-
(2009)
Angew Chem Int Ed Engl
, vol.48
, pp. 1740-1752
-
-
Bulic, B.1
Pickhardt, M.2
Schmidt, B.3
Mandelkow, E.M.4
Waldmann, H.5
Mandelkow, E.6
|