Mechanism of μ-conotoxin PIIIA binding to the voltage-gated Na + channel NaV1.4

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Chen, Rong ^a   Robinson, Anna ^a   Chung, Shin Ho ^a  

^a AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ARGININE; CONOTOXIN; GLUTAMIC ACID; LYSINE; MU CONOTOXIN PIIIA; SODIUM CHANNEL NAV1.4; TETRODOTOXIN; UNCLASSIFIED DRUG; ION; MU-CONOTOXIN PIIIA; PROTEIN BINDING;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; DISSOCIATION CONSTANT; MOLECULAR DYNAMICS; MOLECULAR MODEL; MUTAGENESIS; PREDICTION; PROTEIN BINDING; TOXIN ANALYSIS; TOXIN STRUCTURE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HUMAN; METABOLISM; MOLECULAR DOCKING; MOLECULAR GENETICS; MUTATION; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; BINDING SITES; CONOTOXINS; HUMANS; IONS; MODELS, MOLECULAR; MOLECULAR DOCKING SIMULATION; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; MUTATION; NAV1.4 VOLTAGE-GATED SODIUM CHANNEL; PROTEIN BINDING; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84899829088     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0093267     Document Type: Article

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