Molecular determinants for the subtype specificity of μ-conotoxin SIIIA targeting neuronal voltage-gated sodium channels

Neuropharmacology

Volumn 61, Issue 1-2, 2011, Pages 105-111

  Leipold, Enrico ^a   Markgraf, René ^a   Miloslavina, Alesia ^b   Kijas, Michael ^a   Schirmeyer, Jana ^a   Imhof, Diana ^b   Heinemann, Stefan H ^a  

^a JENA UNIVERSITY HOSPITAL   (Germany)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Conotoxin; Channel block; Pain; Receptor site 1; Voltage gated sodium channel

Indexed keywords

OMEGA CONOTOXIN; OMEGA CONOTOXIN SIIIA; SODIUM CHANNEL NAV1.4; SODIUM CHANNEL NAV1.5; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL;

ANIMAL CELL; ARTICLE; BINDING SITE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; DRUG TARGETING; HUMAN; HUMAN CELL; IC 50; NERVE CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PHARMACOLOGICAL BLOCKING; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CONOTOXINS; CONUS SNAIL; DRUG DELIVERY SYSTEMS; HEK293 CELLS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; NEURONS; RATS; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS;

EID: 79957868138     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2011.03.008     Document Type: Article

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