Multiple, distributed interactions of μ-conotoxin PIIIA associated with broad targeting among voltage-gated sodium channels

Biochemistry

Volumn 50, Issue 1, 2011, Pages 116-124

  McArthur, Jeff R ^a   Ostroumov, Vitaly ^a   Al Sabi, Ahmed ^a   McMaster, Denis ^b   French, Robert J ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING AFFINITIES; C-TERMINUS; CONOTOXINS; DISTRIBUTED INTERACTION; ISOFORMS; RESIDUAL CURRENT; SEQUENCE CONSERVATION; SEQUENCE IDENTITY; SINGLE CHANNELS; SINGLE-CHANNEL; SKELETAL MUSCLE; SODIUM CHANNEL; WILD TYPES;

AMINO ACIDS; BINDING ENERGY; MUSCLE; SODIUM;

TOXIC MATERIALS;

ALANINE; ARGININE; CONOTOXIN; GLUTAMINE; HISTIDINE; VOLTAGE GATED CALCIUM CHANNEL;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING KINETICS; DISSOCIATION CONSTANT; MOLECULAR INTERACTION; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; STEADY STATE;

AMINO ACID SEQUENCE; ANIMALS; CONOTOXINS; CONUS SNAIL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUSCLE, SKELETAL; MUTATION; NAV1.2 VOLTAGE-GATED SODIUM CHANNEL; NAV1.4 VOLTAGE-GATED SODIUM CHANNEL; PROTEIN BINDING; RATS; SEQUENCE ALIGNMENT; SODIUM CHANNEL BLOCKERS;

EID: 78650902764     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi101316y     Document Type: Article

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