Interactions of key charged residues contributing to selective block of neuronal sodium channels by μ-Conotoxin KIIIA

Molecular Pharmacology

Volumn 80, Issue 4, 2011, Pages 573-584

  McArthur, J R ^a   Singh, G ^b   McMaster, D ^a   Winkfein, R ^a   Tieleman, D P ^b   French, Robert J ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CONOTOXIN; MU CONOTOXIN KIIIA; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL;

AMINO TERMINAL SEQUENCE; ARTICLE; BRAIN; CONTROLLED STUDY; ELECTROPHYSIOLOGY; EPILEPSY; EXCITATION; GENE MUTATION; HEART ARRHYTHMIA; HEART MUSCLE; HUMAN; HUMAN CELL; MODULATION; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; MYOTONIA; NERVE CONDUCTION; PAIN; PERIPHERAL NERVE; PH; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; SIGNAL TRANSDUCTION; SODIUM CURRENT; SUBSTITUTION REACTION; TITRIMETRY; WILD TYPE;

AMINO ACID SEQUENCE; CONOTOXINS; DOSE-RESPONSE RELATIONSHIP, DRUG; HEK293 CELLS; HUMANS; MOLECULAR SEQUENCE DATA; NEURONS; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS;

EID: 80053200238     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.111.073460     Document Type: Article

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