Overexpression of glutathione peroxidase 4 prevents β-cell dysfunction induced by prolonged elevation of lipids in vivo

American Journal of Physiology - Endocrinology and Metabolism

Volumn 305, Issue 2, 2013, Pages

  Koulajian, Khajag ^a   Ivovic, Alexander ^a   Ye, Kaitai ^a   Desai, Tejas ^a   Shah, Anu ^a,b,c   George Fantus, I ^a,b,c,g   Ran, Qitao ^d,e,f   Giacca, Adria ^a,g  

^a UNIVERSITY OF TORONTO   (Canada)

^b MOUNT SINAI HOSPITAL   (Canada)

^c UNIVERSITY HEALTH NETWORK   (Canada)

^d Mays Cancer Center at UT Health San Antonio   (United States)

^e UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^f SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

^g UNIVERSITY OF TORONTO   (Canada)

Author keywords

Glutathione peroxidase 4; In vivo; Lipid peroxide; Lipotoxicity; Oxidative stress; cell dysfunction

Indexed keywords

C PEPTIDE; LIPID PEROXIDE; MALONALDEHYDE; OLEIC ACID; PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE PEROXIDASE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL PROTECTION; CELL STRUCTURE; CONTROLLED STUDY; EX VIVO STUDY; HYPERGLYCEMIA; IN VITRO STUDY; IN VIVO STUDY; INSULIN RESISTANCE; LIPID PEROXIDATION; MALE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 84880144523     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00481.2012     Document Type: Article

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