Thioredoxin 1 overexpression extends mainly the earlier part of life span in mice

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 66 A, Issue 12, 2011, Pages 1286-1299

  Pérez, Viviana I ^a,b   Cortez, Lisa A ^a   Lew, Christie M ^a   Rodriguez, Marisela ^a   Webb, Celeste R ^a   Van Remmen, Holly ^a,b,c   Chaudhuri, Asish ^a,c,d   Qi, Wenbo ^a   Lee, Shuko ^c   Bokov, Alex ^a   Fok, Wilson ^b   Jones, Dean ^e   Richardson, Arlan ^a,b,c   Yodoi, Junji ^f   Zhang, Yiqiang ^a   Tominaga, Kaoru ^a,b   Hubbard, Gene B ^a,b   Ikeno, Yuji ^a,b,c  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b Mays Cancer Center at UT Health San Antonio   (United States)

^c SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

^d Department of Biochemistry ^*  (United States)

^e EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f KYOTO UNIVERSITY   (Japan)

Author keywords

Aging; Oxidative stress; Protein carbonylation; Thioredoxin; Transgenic mouse

Indexed keywords

MUS; MUS MUSCULUS;

8 OXO 7 HYDRODEOXYGUANOSINE; 8-OXO-7-HYDRODEOXYGUANOSINE; ANTIOXIDANT; APOPTOSIS SIGNAL REGULATING KINASE 1; DEOXYGUANOSINE; DIQUAT; DRUG DERIVATIVE; GLRX PROTEIN, MOUSE; GLUTAREDOXIN; GLUTATHIONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MAP3K5 PROTEIN, MOUSE; THIOREDOXIN; TXN1 PROTEIN, MOUSE; TXN2 PROTEIN, MOUSE;

AGING; ANIMAL; ARTICLE; BIOLOGICAL MODEL; C57BL MOUSE; FEMALE; GENETICS; LIPID PEROXIDATION; LIVER; LONGEVITY; MALE; METABOLISM; MOUSE; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PATHOLOGY; PHYSIOLOGY; SEXUAL DEVELOPMENT; TRANSGENIC MOUSE; UPREGULATION;

AGING; ANIMALS; ANTIOXIDANTS; DEOXYGUANOSINE; DIQUAT; FEMALE; GLUTAREDOXINS; GLUTATHIONE; LIPID PEROXIDATION; LIVER; LONGEVITY; MALE; MAP KINASE KINASE KINASE 5; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MODELS, BIOLOGICAL; NF-KAPPA B; OXIDATION-REDUCTION; OXIDATIVE STRESS; SEX CHARACTERISTICS; THIOREDOXINS; UP-REGULATION;

EID: 81055144368     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/glr125     Document Type: Article

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