Genetic disruption of sod1 gene causes glucose intolerance and impairs b-cell function

Diabetes

Volumn 62, Issue 12, 2013, Pages 4201-4207

  Muscogiuri, Giovanna ^a   Salmon, Adam B ^b,c   Aguayo Mazzucato, Cristina ^d   Li, Mengyao ^a   Balas, Bogdan ^a   Guardado Mendoza, Rodolfo ^a   Giaccari, Andrea ^e   Reddick, Robert L ^a   Reyna, Sara M ^a   Weir, Gordon ^d   DeFronzo, Ralph A ^a   Van Remmen, Holly ^b,c   Musi, Nicolas ^a,b,c  

^a University of Texas Health Science Center at San Antonio   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

^d JOSLIN DIABETES CENTER   (United States)

^e FONDAZIONE POLICLINICO UNIVERSITARIO A GEMELLI IRCCS   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; GLUCAGON; GLUCOSE; INSULIN;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; FAT INTAKE; GENE DISRUPTION; GLUCAGON BLOOD LEVEL; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE; GLUCOSE TOLERANCE TEST; HYPERGLYCEMIA; IMPAIRED GLUCOSE TOLERANCE; INSULIN BLOOD LEVEL; INSULIN RELEASE; INSULIN SENSITIVITY; LIPID DIET; MALE; MORPHOMETRICS; MOUSE; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL FUNCTION; PRIORITY JOURNAL; WILD TYPE;

ANIMALS; BLOOD GLUCOSE; DIET, HIGH-FAT; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; INSULIN; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; MALE; MICE; MICE, KNOCKOUT; OXIDATIVE STRESS; SUPEROXIDE DISMUTASE;

EID: 84891774835     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db13-0314     Document Type: Article

References (35)

1. Morrow JD. Quantification of isoprostanes as indices of oxidant stress and the risk of atherosclerosis in humans. Arterioscler Thromb Vasc Biol 2005; 25:279-286
2. Oranje WA, Wolffenbuttel BH. Lipid peroxidation and atherosclerosis in type II diabetes. J Lab Clin Med 1999;134:19-32
3. Park K, Gross M, Lee DH, et al. Oxidative stress and insulin resistance: the coronary artery risk development in young adults study. Diabetes Care 2009;32:1302-1307
4. Ogihara T, Asano T, Katagiri H, et al. Oxidative stress induces insulin resistance by activating the nuclear factor-kB pathway and disrupting normal subcellular distribution of phosphatidylinositol 3-kinase. Diabetologia 2004;47:794-805
5. Styskal J, Van Remmen H, Richardson A, Salmon AB. Oxidative stress and diabetes: what can we learn about insulin resistance from antioxidant mutant mouse models? Free Radic Biol Med 2012;52:46-58
6. Elchuri S, Oberley TD, Qi W, et al. CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life. Oncogene 2005;24:367-380
7. Muller FL, Song W, Liu Y, et al. Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophy. Free Radic Biol Med 2006;40:1993-2004
8. Liang H, Balas B, Tantiwong P, et al. Whole body overexpression of PGC-1a has opposite effects on hepatic and muscle insulin sensitivity. Am J Physiol Endocrinol Metab 2009;296:E945-E954
9. Bratthauer GL. The avidin-biotin complex (ABC) method and other avidinbiotin binding methods. Methods Mol Biol 2010;588:257-270
10. Mandarim-de-Lacerda CA. Stereological tools in biomedical research. An Acad Bras Cienc 2003;75:469-486
11. Gotoh M, Maki T, Satomi S, et al. Reproducible high yield of rat islets by stationary in vitro digestion following pancreatic ductal or portal venous collagenase injection. Transplantation 1987;43:725-730
12. Schuppin GT, Bonner-Weir S, Montana E, Kaiser N, Weir GC. Replication of adult pancreatic-beta cells cultured on bovine corneal endothelial cell extracellular matrix. In Vitro Cell Dev Biol Anim 1993;29A:339-344
13. Bhattacharya A, Lustgarten M, Shi Y, et al. Increased mitochondrial matrixdirected superoxide production by fatty acid hydroperoxides in skeletal muscle mitochondria. Free Radic Biol Med 2011;50:592-601
14. Zhou M, Diwu Z, Panchuk-Voloshina N, Haugland RP: A stable nonfluorescent derivative of resorufin for the fluorometric determination of trace hydrogen peroxide: applications in detecting the activity of phagocyte NADPH oxidase and other oxidases. Anal Biochem. 1997;253:162-168
15. Ghosh S, Lertwattanarak R, Lefort N, et al. Reduction in reactive oxygen species production by mitochondria from elderly subjects with normal and impaired glucose tolerance. Diabetes 2011;60:2051-2060
16. Ward WF, Qi W, Van Remmen H, Zackert WE, Roberts LJ 2nd, Richardson A. Effects of age and caloric restriction on lipid peroxidation: measurement of oxidative stress by F2-isoprostane levels. J Gerontol A Biol Sci Med Sci 2005;60:847-851
17. Asplin CM, Werner PL, Halter JB, Hollander PM, Palmer JP. Autonomic nervous system control of glucagon secretion during neuroglucopenia. Endocrinology 1983;112:1585-1589
18. Evans JL, Maddux BA, Goldfine ID. The molecular basis for oxidative stress-induced insulin resistance. Antioxid Redox Signal 2005;7:1040-1052
19. Kozlovsky N, Rudich A, Potashnik R, Bashan N. Reactive oxygen species activate glucose transport in L6 myotubes. Free Radic Biol Med 1997;23: 859-869
20. Higaki Y, Mikami T, Fujii N, et al. Oxidative stress stimulates skeletal muscle glucose uptake through a phosphatidylinositol 3-kinase-dependent pathway. Am J Physiol Endocrinol Metab 2008;294:E889-E897
21. Folli F, Corradi D, Fanti P, et al. The role of oxidative stress in the pathogenesis of type 2 diabetes mellitus micro-and macrovascular complications: avenues for a mechanistic-based therapeutic approach. Curr Diabetes Rev 2011;7:313-324
22. Kim EK, Choi EJ. Pathological roles of MAPK signaling pathways in human diseases. Biochim Biophys Acta 2010;1802:396-405
23. Sigala I, Zacharatos P, Toumpanakis D, et al. MAPKs and NF-kB differentially regulate cytokine expression in the diaphragm in response to resistive breathing: the role of oxidative stress. Am J Physiol Regul Integr Comp Physiol 2011;300:R1152-R1162
24. Ferrannini E, Simonson DC, Katz LD, et al. The disposal of an oral glucose load in patients with non-insulin-dependent diabetes. Metabolism 1988;37: 79-85
25. Abruzzo PM, Esposito F, Marchionni C, et al. Moderate exercise training induces ROS-related adaptations to skeletal muscles. Int J Sports Med 2013;34:676-687
26. McClung JP, Roneker CA, Mu W, et al. Development of insulin resistance and obesity in mice overexpressing cellular glutathione peroxidase. Proc Natl Acad Sci U S A 2004;101:8852-8857
27. Goldstein BJ, Mahadev K, Wu X. Redox paradox: insulin action is facilitated by insulin-stimulated reactive oxygen species with multiple potential signaling targets. Diabetes 2005;54:311-321
28. Kaneto H, Fujii J, Myint T, et al. Reducing sugars trigger oxidative modification and apoptosis in pancreatic beta-cells by provoking oxidative stress through the glycation reaction. Biochem J 1996; 320:855-863
29. Kaneto H, Kajimoto Y, Miyagawa J, et al. Beneficial effects of antioxidants in diabetes: possible protection of pancreatic beta-cells against glucose toxicity. Diabetes 1999;48:2398-2406
30. Ihara Y, Toyokuni S, Uchida K, et al. Hyperglycemia causes oxidative stress in pancreatic beta-cells of GK rats, a model of type 2 diabetes. Diabetes 1999;48:927-932
31. Tiedge M, Lortz S, Drinkgern J, Lenzen S. Relation between antioxidant enzyme gene expression and antioxidative defense status of insulinproducing cells. Diabetes 1997;46:1733-1742
32. Tanaka Y, Tran PO, Harmon J, Robertson RP. A role for glutathione peroxidase in protecting pancreatic beta cells against oxidative stress in a model of glucose toxicity. Proc Natl Acad Sci U S A 2002;99:12363-12368
33. Babu DA, Deering TG, Mirmira RG. A feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis. Mol Genet Metab 2007;92:43-55
34. Wang X, Vatamaniuk MZ, Roneker CA, et al. Knockouts of SOD1 and GPX1 exert different impacts on murine islet function and pancreatic integrity. Antioxid Redox Signal 2011;14:391-401
35. Hamilton RT, Bhattacharya A, Walsh ME, et al. Elevated protein carbonylation, and misfolding in sciatic nerve from db/db and Sod1(-/-) mice: plausible link between oxidative stress and demyelination. PLoS ONE 2013;8:e65725