Overexpression of thioredoxin-1 in transgenic mice attenuates Adriamycin-induced cardiotoxicity

Circulation

Volumn 106, Issue 11, 2002, Pages 1403-1409

  Shioji, Keisuke ^a   Kishimoto, Chiharu ^a   Nakamura, Hajime ^a   Masutani, Hiroshi ^a   Yuan, Zuyi ^a   Oka, Shin ichi ^a   Yodoi, Junji ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Antioxidants; Cardiomyopathy; Free radicals

Indexed keywords

CARBONYL DERIVATIVE; DOXORUBICIN; HYDROXYL RADICAL; LACTATE DEHYDROGENASE; RECOMBINANT PROTEIN; THIOREDOXIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOTOXICITY; CELL DAMAGE; CONTROLLED STUDY; DOSE RESPONSE; ELECTRON MICROSCOPY; HEART MUSCLE CELL; HEART PROTECTION; IMMUNOHISTOCHEMISTRY; MITOCHONDRION; MUSCLE FIBRIL; NEWBORN; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TRANSGENIC MOUSE; WESTERN BLOTTING;

ANIMALS; ANIMALS, NEWBORN; ANTINEOPLASTIC AGENTS; CARDIOMYOPATHIES; CARDIOTONIC AGENTS; CELLS, CULTURED; DOXORUBICIN; HYDROXYL RADICAL; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; MYOCARDIUM; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROTEINS; RATS; RATS, INBRED LEW; REACTIVE OXYGEN SPECIES; SURVIVAL ANALYSIS; THIOREDOXIN; UP-REGULATION;

EID: 0037056109     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000027817.55925.B4     Document Type: Article

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