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Volumn 64, Issue 11, 2009, Pages 1114-1125

Overexpression of Mn superoxide dismutase does not increase life span in mice

Author keywords

Aging; Mn superoxide dismutase; Oxidative damage; Pathology

Indexed keywords

INVERTEBRATA; MAMMALIA; MUS;

EID: 70350439125     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/glp100     Document Type: Article
Times cited : (159)

References (67)
  • 1
    • 0015319592 scopus 로고
    • The biologic clock: The mitochondria?
    • Harman D. The biologic clock: the mitochondria? J Am Geriatr Soc. 1972; 20: 145-147.
    • (1972) J Am Geriatr Soc. , vol.20 , pp. 145-147
    • Harman, D.1
  • 2
    • 0031700784 scopus 로고    scopus 로고
    • The trail to superoxide dismutase
    • Fridovich I. The trail to superoxide dismutase. Protein Sci. 1998; 7: 2688-2690.
    • (1998) Protein Sci. , vol.7 , pp. 2688-2690
    • Fridovich, I.1
  • 3
    • 0033396970 scopus 로고    scopus 로고
    • Fundamental aspects of reactive oxygen species, or what ' s the matter with oxygen?
    • Fridovich I. Fundamental aspects of reactive oxygen species, or what ' s the matter with oxygen? Ann N Y Acad Sci. 1999; 893: 13-18.
    • (1999) Ann N y Acad Sci. , vol.893 , pp. 13-18
    • Fridovich, I.1
  • 4
    • 0034626747 scopus 로고    scopus 로고
    • Genetic pathways that regulate ageing in model organisms
    • Guarente L, Kenyon C. Genetic pathways that regulate ageing in model organisms. Nature. 2000; 408: 255-262.
    • (2000) Nature , vol.408 , pp. 255-262
    • Guarente, L.1    Kenyon, C.2
  • 5
    • 0036245337 scopus 로고    scopus 로고
    • Mechanisms of ageing: Public or private?
    • Partridge L, Gems D. Mechanisms of ageing: public or private? Nat Rev Genet. 2002; 3: 165-175.
    • (2002) Nat Rev Genet , vol.3 , pp. 165-175
    • Partridge, L.1    Gems, D.2
  • 6
    • 0032782364 scopus 로고    scopus 로고
    • The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans
    • Honda Y, Honda S. The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans. FASEB J. 1999; 13: 1385-1393.
    • (1999) FASEB J. , vol.13 , pp. 1385-1393
    • Honda, Y.1    Honda, S.2
  • 7
    • 0042092531 scopus 로고    scopus 로고
    • Genes that act downstream of DAF-16 to infl uence the lifespan of Caenorhabditis elegans
    • Murphy CT, McCarroll SA, Bargmann CI, et al. Genes that act downstream of DAF-16 to infl uence the lifespan of Caenorhabditis elegans. Nature. 2003; 424: 277-283.
    • (2003) Nature , vol.424 , pp. 277-283
    • Murphy, C.T.1    McCarroll, S.A.2    Bargmann, C.I.3
  • 8
    • 27844561111 scopus 로고    scopus 로고
    • Regulation of oxidative stress by the anti-aging hormone Klotho
    • Yamamoto M, Clark JD, Pastor JV, et al. Regulation of oxidative stress by the anti-aging hormone Klotho. J Biol Chem. 2005; 280: 38029-38034.
    • (2005) J Biol Chem. , vol.280 , pp. 38029-38034
    • Yamamoto, M.1    Clark, J.D.2    Pastor, J.V.3
  • 9
    • 34547097247 scopus 로고    scopus 로고
    • Brain IRS2 signaling coordinates life span and nutrient homeostasis
    • Taguchi A, Wartschow LM, White MF. Brain IRS2 signaling coordinates life span and nutrient homeostasis. Science. 2007; 317: 369-372.
    • (2007) Science , vol.317 , pp. 369-372
    • Taguchi, A.1    Wartschow, L.M.2    White, M.F.3
  • 10
    • 0034993409 scopus 로고    scopus 로고
    • Reduced levels of thyroid hormones, insulin, and glucose, and lower body core temperature in the growth hormone receptor/binding protein knockout mouse
    • Hauck SJ, Hunter WS, Danilovich N, Kopchick JJ, Bartke A. Reduced levels of thyroid hormones, insulin, and glucose, and lower body core temperature in the growth hormone receptor/binding protein knockout mouse. Exp Biol Med (Maywood). 2001; 226: 552-558.
    • (2001) Exp Biol Med (Maywood) , vol.226 , pp. 552-558
    • Hauck, S.J.1    Hunter, W.S.2    Danilovich, N.3    Kopchick, J.J.4    Bartke, A.5
  • 11
    • 18144391553 scopus 로고    scopus 로고
    • Estrogen, insulin, and dietary signals cooperatively regulate longevity signals to enhance resistance to oxidative stress in mice
    • Baba T, Shimizu T, Suzuki Y, et al. Estrogen, insulin, and dietary signals cooperatively regulate longevity signals to enhance resistance to oxidative stress in mice. J Biol Chem. 2005; 280: 16417-16426.
    • (2005) J Biol Chem. , vol.280 , pp. 16417-16426
    • Baba, T.1    Shimizu, T.2    Suzuki, Y.3
  • 12
    • 15844429977 scopus 로고    scopus 로고
    • Superoxide dismutase activity is essential for stationary phase survival in Saccharomyces cerevisiae. Mitochondrial production of toxic oxygen species in vivo
    • Longo VD, Gralla EB, Valentine JS. Superoxide dismutase activity is essential for stationary phase survival in Saccharomyces cerevisiae. Mitochondrial production of toxic oxygen species in vivo. J Biol Chem. 1996; 271: 12275-12280.
    • (1996) J Biol Chem. , vol.271 , pp. 12275-12280
    • Longo, V.D.1    Gralla, E.B.2    Valentine, J.S.3
  • 13
  • 14
    • 0035989388 scopus 로고    scopus 로고
    • Induced overexpression of mitochondrial Mn-superoxide dismutase extends the life span of adult Drosophila melanogaster
    • Sun J, Folk D, Bradley TJ, Tower J. Induced overexpression of mitochondrial Mn-superoxide dismutase extends the life span of adult Drosophila melanogaster. Genetics. 2002; 161: 661-672.
    • (2002) Genetics , vol.161 , pp. 661-672
    • Sun, J.1    Folk, D.2    Bradley, T.J.3    Tower, J.4
  • 15
    • 0029838063 scopus 로고    scopus 로고
    • Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutasedefi cient mice
    • Lebovitz RM, Zhang H, Vogel H, et al. Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutasedefi cient mice. Proc Natl Acad Sci U S A. 1996; 93: 9782-9787.
    • (1996) Proc Natl Acad Sci U S A. , vol.93 , pp. 9782-9787
    • Lebovitz, R.M.1    Zhang, H.2    Vogel, H.3
  • 16
    • 0028827252 scopus 로고
    • Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase
    • Li Y, Huang TT, Carlson EJ, et al. Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase. Nat Genet. 1995; 11: 376-381.
    • (1995) Nat Genet , vol.11 , pp. 376-381
    • Li, Y.1    Huang, T.T.2    Carlson, E.J.3
  • 17
    • 28644442428 scopus 로고    scopus 로고
    • SOD2 overexpression: Enhanced mitochondrial tolerance but absence of effect on UCP activity
    • Silva JP, Shabalina IG, Dufour E, et al. SOD2 overexpression: enhanced mitochondrial tolerance but absence of effect on UCP activity. EMBO J. 2005; 24: 4061-4070.
    • (2005) EMBO J. , vol.24 , pp. 4061-4070
    • Silva, J.P.1    Shabalina, I.G.2    Dufour, E.3
  • 18
    • 0035878691 scopus 로고    scopus 로고
    • Overexpression of mitochondrial manganese superoxide dismutase protects against radiation-induced cell death in the human hepatocellular carcinoma cell line HLE
    • Motoori S, Majima HJ, Ebara M, et al. Overexpression of mitochondrial manganese superoxide dismutase protects against radiation-induced cell death in the human hepatocellular carcinoma cell line HLE. Cancer Res. 2001; 61: 5382-5388.
    • (2001) Cancer Res. , vol.61 , pp. 5382-5388
    • Motoori, S.1    Majima, H.J.2    Ebara, M.3
  • 19
    • 0035887747 scopus 로고    scopus 로고
    • Strain-dependent high-level expression of a transgene for manganese superoxide dismutase is associated with growth retardation and decreased fertility
    • Raineri I, Carlson EJ, Gacayan R, et al. Strain-dependent high-level expression of a transgene for manganese superoxide dismutase is associated with growth retardation and decreased fertility. Free Radic Biol Med. 2001; 31: 1018-1030.
    • (2001) Free Radic Biol Med. , vol.31 , pp. 1018-1030
    • Raineri, I.1    Carlson, E.J.2    Gacayan, R.3
  • 20
    • 36949079555 scopus 로고
    • Biochemical and osmotic properties of skeletal muscle mitochondria
    • Chappell JB, Perry SV. Biochemical and osmotic properties of skeletal muscle mitochondria. Nature. 1954; 173: 1094-1095.
    • (1954) Nature , vol.173 , pp. 1094-1095
    • Chappell, J.B.1    Perry, S.V.2
  • 22
    • 10344221083 scopus 로고    scopus 로고
    • Complex III releases superoxide to both sides of the inner mitochondrial membrane
    • Muller FL, Liu Y, Van Remmen H. Complex III releases superoxide to both sides of the inner mitochondrial membrane. J Biol Chem. 2004; 279: 49064-49073.
    • (2004) J Biol Chem. , vol.279 , pp. 49064-49073
    • Muller, F.L.1    Liu, Y.2    Van Remmen, H.3
  • 23
    • 0033102629 scopus 로고    scopus 로고
    • Characterization of the antioxidant status of the heterozygous manganese superoxide dismutase knockout mouse
    • Van Remmen H, Salvador C, Yang H, Huang TT, Epstein CJ, Richardson A. Characterization of the antioxidant status of the heterozygous manganese superoxide dismutase knockout mouse. Arch Biochem Biophys. 1999; 363: 91-97.
    • (1999) Arch Biochem Biophys , vol.363 , pp. 91-97
    • Van Remmen, H.1    Salvador, C.2    Yang, H.3    Huang, T.T.4    Epstein, C.J.5    Richardson, A.6
  • 24
    • 0031573401 scopus 로고    scopus 로고
    • A stable nonfl uorescent derivative of resorufin for the fl uorometric determination of trace hydrogen peroxide: Applications in detecting the activity of phagocyte NADPH oxidase and other oxidases
    • Zhou M, Diwu Z, Panchuk-Voloshina N, Haugland RP. A stable nonfl uorescent derivative of resorufin for the fl uorometric determination of trace hydrogen peroxide: applications in detecting the activity of phagocyte NADPH oxidase and other oxidases. Anal Biochem. 1997; 253: 162-168.
    • (1997) Anal Biochem , vol.253 , pp. 162-168
    • Zhou, M.1    Diwu, Z.2    Panchuk-Voloshina, N.3    Haugland, R.P.4
  • 25
    • 0028239059 scopus 로고
    • Assays using horseradish peroxidase and phenolic substrates require superoxide dismutase for accurate determination of hydrogen peroxide production by neutrophils
    • Kettle AJ, Carr AC, Winterbourn CC. Assays using horseradish peroxidase and phenolic substrates require superoxide dismutase for accurate determination of hydrogen peroxide production by neutrophils. Free Radic Biol Med. 1994; 17: 161-164.
    • (1994) Free Radic Biol Med. , vol.17 , pp. 161-164
    • Kettle, A.J.1    Carr, A.C.2    Winterbourn, C.C.3
  • 26
    • 84953660531 scopus 로고
    • Reactivity of HO 2 - /O 2 - Radicals in aqueous solution
    • Bielski BHJ. Reactivity of HO 2 - /O 2 - radicals in aqueous solution. J Phys Chem Ref Data. 1985; 14: 1041-1091.
    • (1985) J Phys Chem Ref Data , vol.14 , pp. 1041-1091
    • Bielski, B.H.J.1
  • 27
    • 32244448364 scopus 로고    scopus 로고
    • Alterations in mitochondrial function, hydrogen peroxide release and oxidative damage in mouse hind-limb skeletal muscle during aging
    • Mansouri A, Muller FL, Liu Y, et al. Alterations in mitochondrial function, hydrogen peroxide release and oxidative damage in mouse hind-limb skeletal muscle during aging. Mech Ageing Dev. 2006; 127: 298-306.
    • (2006) Mech Ageing Dev. , vol.127 , pp. 298-306
    • Mansouri, A.1    Muller, F.L.2    Liu, Y.3
  • 29
    • 0036121191 scopus 로고    scopus 로고
    • Aconitase: Sensitive target and measure of superoxide
    • Gardner PR. Aconitase: sensitive target and measure of superoxide. Meth Enzymol. 2002; 349: 9-23.
    • (2002) Meth Enzymol , vol.349 , pp. 9-23
    • Gardner, P.R.1
  • 30
    • 0029064257 scopus 로고
    • Superoxide radical and iron modulate aconitase activity in mammalian cells
    • Gardner PR, Raineri I, Epstein LB, White CW. Superoxide radical and iron modulate aconitase activity in mammalian cells. J Biol Chem. 1995; 270: 13399-13405.
    • (1995) J Biol Chem. , vol.270 , pp. 13399-13405
    • Gardner, P.R.1    Raineri, I.2    Epstein, L.B.3    White, C.W.4
  • 31
    • 77957003282 scopus 로고
    • Mitochondrial respiratory control and the polarographic measurement of ADP: O ratios
    • Estabrook RW. Mitochondrial respiratory control and the polarographic measurement of ADP: O ratios. Meth Enzymol. 1974; 10: 41-47.
    • (1974) Meth Enzymol. , vol.10 , pp. 41-47
    • Estabrook, R.W.1
  • 32
    • 1842869830 scopus 로고    scopus 로고
    • Mass spectrometric quantification of F2-isoprostanes as indicators of oxidant stress
    • Morrow JD, Roberts LJ, II. Mass spectrometric quantification of F2-isoprostanes as indicators of oxidant stress. Methods Mol Biol. 2002; 186: 57-66.
    • (2002) Methods Mol Biol. , vol.186 , pp. 57-66
    • Morrow, J.D.1    Roberts II, L.J.2
  • 33
    • 23244442108 scopus 로고    scopus 로고
    • Effects of age and caloric restriction on lipid peroxidation: Measurement of oxidative stress by F2-isoprostane levels
    • Ward WF, Qi W, Van Remmen H, Zackert WE, Roberts JL, Richardson A. Effects of age and caloric restriction on lipid peroxidation: measurement of oxidative stress by F2-isoprostane levels. J. Gerontol. 2005; 60 ( 7 ): 847-851.
    • (2005) J. Gerontol. , vol.60 , Issue.7 , pp. 847-851
    • Ward, W.F.1    Qi, W.2    Van Remmen, H.3    Zackert, W.E.4    Roberts, J.L.5    Richardson, A.6
  • 35
    • 0023127085 scopus 로고
    • Use of fl uorescein hydrazide and fl uorescein thiosemicarbazide reagents for the fl uorometric determination of protein carbonyl groups and for the detection of oxidized protein on polyacrylamide gels
    • Ahn B, Rhee SG, Stadtman ER. Use of fl uorescein hydrazide and fl uorescein thiosemicarbazide reagents for the fl uorometric determination of protein carbonyl groups and for the detection of oxidized protein on polyacrylamide gels. Anal Biochem. 1987; 161: 245-257.
    • (1987) Anal Biochem. , vol.161 , pp. 245-257
    • Ahn, B.1    Rhee, S.G.2    Stadtman, E.R.3
  • 36
    • 0032211827 scopus 로고    scopus 로고
    • Overexpression of MnSOD protects against myocardial ischemia/reperfusion injury in transgenic mice
    • Chen Z, Siu B, Ho YS, et al. Overexpression of MnSOD protects against myocardial ischemia/reperfusion injury in transgenic mice. J Mol Cell Cardiol. 1998; 30: 2281-2289.
    • (1998) J Mol Cell Cardiol , vol.30 , pp. 2281-2289
    • Chen, Z.1    Siu, B.2    Ho, Y.S.3
  • 37
    • 0028108210 scopus 로고
    • Comparative in vitro effects of sodium arsenite and sodium arsenate on neuroblastoma cells
    • Repetto G, Sanz P, Repetto M. Comparative in vitro effects of sodium arsenite and sodium arsenate on neuroblastoma cells. Toxicology. 1994; 92: 143-153.
    • (1994) Toxicology , vol.92 , pp. 143-153
    • Repetto, G.1    Sanz, P.2    Repetto, M.3
  • 38
    • 0025841730 scopus 로고
    • Reduction in rate of occurrence of age related lesions in dietary restricted laboratory mice
    • Bronson RT, Lipman RD. Reduction in rate of occurrence of age related lesions in dietary restricted laboratory mice. Growth Dev Aging. 1991; 55: 169-184.
    • (1991) Growth Dev Aging , vol.55 , pp. 169-184
    • Bronson, R.T.1    Lipman, R.D.2
  • 39
    • 33646588683 scopus 로고    scopus 로고
    • Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of agedependent skeletal muscle atrophy
    • Muller FL, Song W, Liu Y, et al. Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of agedependent skeletal muscle atrophy. Free Radic Biol Med. 2006; 40: 1993-2004.
    • (2006) Free Radic Biol Med. , vol.40 , pp. 1993-2004
    • Muller, F.L.1    Song, W.2    Liu, Y.3
  • 40
    • 0026051958 scopus 로고
    • Skeletal muscle atrophy in old rats: Differential changes in the three fiber types
    • Holloszy JO, Chen M, Cartee GD, Young JC. Skeletal muscle atrophy in old rats: differential changes in the three fiber types. Mech Ageing Dev. 1991; 60: 199-213.
    • (1991) Mech Ageing Dev. , vol.60 , pp. 199-213
    • Holloszy, J.O.1    Chen, M.2    Cartee, G.D.3    Young, J.C.4
  • 41
    • 2442711771 scopus 로고    scopus 로고
    • Early-onset calorie restriction conserves fiber number in aging rat skeletal muscle
    • McKiernan SH, Bua E, McGorray J, Aiken J. Early-onset calorie restriction conserves fiber number in aging rat skeletal muscle. FASEB J. 2004; 18: 580-581.
    • (2004) FASEB J. , vol.18 , pp. 580-581
    • McKiernan, S.H.1    Bua, E.2    McGorray, J.3    Aiken, J.4
  • 42
    • 0032582489 scopus 로고    scopus 로고
    • Extended life-span and stress resistance in the Drosophila mutant methuselah
    • Lin YJ, Seroude L, Benzer S. Extended life-span and stress resistance in the Drosophila mutant methuselah. Science. 1998; 282: 943-946.
    • (1998) Science , vol.282 , pp. 943-946
    • Lin, Y.J.1    Seroude, L.2    Benzer, S.3
  • 43
    • 0042203536 scopus 로고    scopus 로고
    • Multiplex stress resistance in cells from long-lived dwarf mice
    • Murakami S, Salmon A, Miller RA. Multiplex stress resistance in cells from long-lived dwarf mice. FASEB J. 2003; 17: 1565-1566.
    • (2003) FASEB J. , vol.17 , pp. 1565-1566
    • Murakami, S.1    Salmon, A.2    Miller, R.A.3
  • 44
    • 38349105900 scopus 로고    scopus 로고
    • Complex i is the major site of mitochondrial superoxide production by paraquat
    • Cocheme HM, Murphy MP. Complex I is the major site of mitochondrial superoxide production by paraquat. J Biol Chem. 2008; 283: 1786-1798.
    • (2008) J Biol Chem. , vol.283 , pp. 1786-1798
    • Cocheme, H.M.1    Murphy, M.P.2
  • 45
    • 0015821035 scopus 로고
    • Bipyridylium quaternary salts and related compounds. V. Pulse radiolysis studies of the reaction of paraquat radical with oxygen. Implications for the mode of action of bipyridyl herbicides
    • Farrington JA, Ebert M, Land EJ, Fletcher K. Bipyridylium quaternary salts and related compounds. V. Pulse radiolysis studies of the reaction of paraquat radical with oxygen. Implications for the mode of action of bipyridyl herbicides. Biochim Biophys Acta. 1973; 314: 372-381.
    • (1973) Biochim Biophys Acta , vol.314 , pp. 372-381
    • Farrington, J.A.1    Ebert, M.2    Land, E.J.3    Fletcher, K.4
  • 48
    • 31344478502 scopus 로고    scopus 로고
    • Housing density does not infl uence the longevity effect of calorie restriction
    • Ikeno Y, Hubbard GB, Lee S, et al. Housing density does not infl uence the longevity effect of calorie restriction. J Gerontol A Biol Sci Med Sci. 2005; 60: 1510-1517.
    • (2005) J Gerontol A Biol Sci Med Sci. , vol.60 , pp. 1510-1517
    • Ikeno, Y.1    Hubbard, G.B.2    Lee, S.3
  • 49
    • 0019483336 scopus 로고
    • Morphologic classification and correlation of incidence of hyperplastic and neoplastic hematopoietic lesions in mice with age
    • Frith CH, Wiley LD. Morphologic classification and correlation of incidence of hyperplastic and neoplastic hematopoietic lesions in mice with age. J Gerontol. 1981; 36: 534-545.
    • (1981) J Gerontol. , vol.36 , pp. 534-545
    • Frith, C.H.1    Wiley, L.D.2
  • 50
    • 21144434217 scopus 로고    scopus 로고
    • Extension of murine lifespan by overexpression of catalase targeted to mitochondria
    • Schriner SE, Linford NJ, Martin GM, et al. Extension of murine lifespan by overexpression of catalase targeted to mitochondria. Science. 2005; 308 ( 5730 ): 1909-1911.
    • (2005) Science , vol.308 , Issue.5730 , pp. 1909-1911
    • Schriner, S.E.1    Linford, N.J.2    Martin, G.M.3
  • 51
    • 0035990351 scopus 로고    scopus 로고
    • Longevity genes in the nematode Caenorhabditis elegans also mediate increased resistance to stress and prevent disease
    • Johnson TE, Henderson S, Murakami S, et al. Longevity genes in the nematode Caenorhabditis elegans also mediate increased resistance to stress and prevent disease. J Inherit Metab Dis. 2002; 25: 197-206.
    • (2002) J Inherit Metab Dis. , vol.25 , pp. 197-206
    • Johnson, T.E.1    Henderson, S.2    Murakami, S.3
  • 52
    • 2942556985 scopus 로고    scopus 로고
    • Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress
    • Van Remmen H, Qi W, Sabia M, et al. Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress. Free Radic Biol Med. 2004; 36: 1625-1634.
    • (2004) Free Radic Biol Med. , vol.36 , pp. 1625-1634
    • Van Remmen, H.1    Qi, W.2    Sabia, M.3
  • 53
    • 0347664057 scopus 로고    scopus 로고
    • IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
    • Holzenberger M, Dupont J, Ducos B, et al. IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice. Nature. 2003; 421: 182-187.
    • (2003) Nature , vol.421 , pp. 182-187
    • Holzenberger, M.1    Dupont, J.2    Ducos, B.3
  • 54
    • 33846345418 scopus 로고    scopus 로고
    • Hippocampal long-term potentiation, memory, and longevity in mice that overexpress mitochondrial superoxide dismutase
    • Hu D, Cao P, Thiels E, et al. Hippocampal long-term potentiation, memory, and longevity in mice that overexpress mitochondrial superoxide dismutase. Neurobiol Learn Mem. 2007; 87: 372-384.
    • (2007) Neurobiol Learn Mem. , vol.87 , pp. 372-384
    • Hu, D.1    Cao, P.2    Thiels, E.3
  • 55
    • 49049104772 scopus 로고    scopus 로고
    • Estimating relative carbonyl levels in muscle microstructures by fl uorescence imaging
    • Feng J, Navratil M, Thompson LV, Arriaga EA. Estimating relative carbonyl levels in muscle microstructures by fl uorescence imaging. Anal Bioanal Chem. 2008; 391: 2591-2598.
    • (2008) Anal Bioanal Chem. , vol.391 , pp. 2591-2598
    • Feng, J.1    Navratil, M.2    Thompson, L.V.3    Arriaga, E.A.4
  • 56
    • 0015788469 scopus 로고
    • Lifespan and incidence of cancer and other diseases in selected long-lived inbred mice and their F 1 hybrids
    • Smith GS, Walford RL, Mickey MR. Lifespan and incidence of cancer and other diseases in selected long-lived inbred mice and their F 1 hybrids. J Natl Cancer Inst. 1973; 50: 1195-1213.
    • (1973) J Natl Cancer Inst. , vol.50 , pp. 1195-1213
    • Smith, G.S.1    Walford, R.L.2    Mickey, M.R.3
  • 57
    • 0013931405 scopus 로고
    • Longevity and gross pathology at death in 22 inbred mouse strains
    • Storer JB. Longevity and gross pathology at death in 22 inbred mouse strains. J Gerontol. 1966; 21: 404-409.
    • (1966) J Gerontol. , vol.21 , pp. 404-409
    • Storer, J.B.1
  • 59
    • 0016680125 scopus 로고
    • Gerontological data of C57BL/6J mice. I. Sex differences in survival curves
    • Kunstyr I, Leuenberger HG. Gerontological data of C57BL/6J mice. I. Sex differences in survival curves. J Gerontol. 1975; 30: 157-162.
    • (1975) J Gerontol. , vol.30 , pp. 157-162
    • Kunstyr, I.1    Leuenberger, H.G.2
  • 60
    • 12144288373 scopus 로고    scopus 로고
    • Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging
    • Van Remmen H, Ikeno Y, Hamilton M, et al. Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging. Physiol Genomics. 2003; 16: 29-37.
    • (2003) Physiol Genomics , vol.16 , pp. 29-37
    • Van Remmen, H.1    Ikeno, Y.2    Hamilton, M.3
  • 61
    • 0031742961 scopus 로고    scopus 로고
    • Manganese superoxide dismutase overexpression attenuates MPTP toxicity
    • Klivenyi P, St Clair D, Wermer M, et al. Manganese superoxide dismutase overexpression attenuates MPTP toxicity. Neurobiol Dis. 1998; 5: 253-258.
    • (1998) Neurobiol Dis. , vol.5 , pp. 253-258
    • Klivenyi, P.1    St Clair, D.2    Wermer, M.3
  • 62
    • 0033659765 scopus 로고    scopus 로고
    • Targeted neuronal gene expression and longevity in Drosophila
    • Phillips JP, Parkes TL, Hilliker AJ. Targeted neuronal gene expression and longevity in Drosophila. Exp Gerontol. 2000; 35: 1157-1164.
    • (2000) Exp Gerontol , vol.35 , pp. 1157-1164
    • Phillips, J.P.1    Parkes, T.L.2    Hilliker, A.J.3
  • 64
    • 53349153165 scopus 로고    scopus 로고
    • Reduction of age-associated pathology in old mice by overexpression of catalase in mitochondria
    • Treuting PM, Linford NJ, Knoblaugh SE, et al. Reduction of age-associated pathology in old mice by overexpression of catalase in mitochondria. J Gerontol A Biol Sci Med Sci. 2008; 63: 813-822.
    • (2008) J Gerontol A Biol Sci Med Sci. , vol.63 , pp. 813-822
    • Treuting, P.M.1    Linford, N.J.2    Knoblaugh, S.E.3
  • 65
    • 0036139524 scopus 로고    scopus 로고
    • Reactive oxygen species and signal transduction
    • Finkel T. Reactive oxygen species and signal transduction. IUBMB Life. 2001; 52: 3-6.
    • (2001) IUBMB Life , vol.52 , pp. 3-6
    • Finkel, T.1
  • 66
    • 0037458619 scopus 로고    scopus 로고
    • Voltage-dependent anion channels control the release of the superoxide anion from mitochondria to cytosol
    • Han D, Antunes F, Canali R, Rettori D, Cadenas E. Voltage-dependent anion channels control the release of the superoxide anion from mitochondria to cytosol. J Biol Chem. 2003; 278: 5557-5563.
    • (2003) J Biol Chem. , vol.278 , pp. 5557-5563
    • Han, D.1    Antunes, F.2    Canali, R.3    Rettori, D.4    Cadenas, E.5


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