Frataxin silencing inactivates mitochondrial complex i in NSC34 motoneuronal cells and alters glutathione homeostasis

International Journal of Molecular Sciences

Volumn 15, Issue 4, 2014, Pages 5789-5806

  Carletti, Barbara ^a   Piermarini, Emanuela ^a   Tozzi, Giulia ^a   Travaglini, Lorena ^a   Torraco, Alessandra ^a   Pastore, Anna ^a   Sparaco, Marco ^b   Petrillo, Sara ^a   Carrozzo, Rosalba ^a   Bertini, Enrico ^a   Piemonte, Fiorella ^a  

^a BAMBINO GESÙ CHILDREN S HOSPITAL   (Italy)

^b G RUMMO HOSPITAL   (Italy)

Author keywords

Friedreich's ataxia; Glutathione; Mitochondrial enzymes; Neurodegeneration; Oxidative stress

Indexed keywords

CITRATE SYNTHASE; CYTOCHROME C OXIDASE; FRATAXIN; GLUTATHIONE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SHORT HAIRPIN RNA; SUCCINATE DEHYDROGENASE (UBIQUINONE); TRANSCRIPTION FACTOR NRF2; UBIQUINOL CYTOCHROME C REDUCTASE; IRON BINDING PROTEIN; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CELL STRUCTURE; CELL VIABILITY ASSAY; CONTROLLED STUDY; ENZYME ACTIVITY; FRIEDREICH ATAXIA; GEL ELECTROPHORESIS; GENE SILENCING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOCYTOCHEMISTRY; MOTONEURON; MOUSE; NEURITE; NONHUMAN; PROTEIN HOMEOSTASIS; REAL TIME POLYMERASE CHAIN REACTION; RESPIRATORY CHAIN; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; CYTOLOGY; GENETICS; HOMEOSTASIS; METABOLISM; MITOCHONDRION; OXIDATIVE STRESS; PATHOLOGY; RNA INTERFERENCE; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; ELECTRON TRANSPORT COMPLEX I; FRIEDREICH ATAXIA; GLUTATHIONE; HOMEOSTASIS; IRON-BINDING PROTEINS; MICE; MITOCHONDRIA; MOTOR NEURONS; OXIDATIVE STRESS; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84898758220     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms15045789     Document Type: Article

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